JP2006516888A5 - - Google Patents
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- Publication number
- JP2006516888A5 JP2006516888A5 JP2004561689A JP2004561689A JP2006516888A5 JP 2006516888 A5 JP2006516888 A5 JP 2006516888A5 JP 2004561689 A JP2004561689 A JP 2004561689A JP 2004561689 A JP2004561689 A JP 2004561689A JP 2006516888 A5 JP2006516888 A5 JP 2006516888A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- nucleic acid
- acid molecule
- disease
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 41
- 102000004196 processed proteins & peptides Human genes 0.000 claims 40
- 108090000765 processed proteins & peptides Proteins 0.000 claims 40
- 150000007523 nucleic acids Chemical class 0.000 claims 36
- 108020004707 nucleic acids Proteins 0.000 claims 35
- 102000039446 nucleic acids Human genes 0.000 claims 35
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 28
- 201000010099 disease Diseases 0.000 claims 23
- 238000000034 method Methods 0.000 claims 21
- 150000001875 compounds Chemical class 0.000 claims 16
- 230000000694 effects Effects 0.000 claims 11
- 239000003446 ligand Substances 0.000 claims 11
- 239000000523 sample Substances 0.000 claims 9
- 102000005741 Metalloproteases Human genes 0.000 claims 6
- 108010006035 Metalloproteases Proteins 0.000 claims 6
- 208000035475 disorder Diseases 0.000 claims 5
- 239000012634 fragment Substances 0.000 claims 5
- 230000035772 mutation Effects 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 208000023275 Autoimmune disease Diseases 0.000 claims 4
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 239000013068 control sample Substances 0.000 claims 4
- 208000027866 inflammatory disease Diseases 0.000 claims 4
- 239000002853 nucleic acid probe Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 238000009739 binding Methods 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 238000003745 diagnosis Methods 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 201000003883 Cystic fibrosis Diseases 0.000 claims 2
- 206010014561 Emphysema Diseases 0.000 claims 2
- 206010019663 Hepatic failure Diseases 0.000 claims 2
- 206010020772 Hypertension Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 230000001154 acute effect Effects 0.000 claims 2
- 230000001476 alcoholic effect Effects 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 2
- 230000000890 antigenic effect Effects 0.000 claims 2
- 230000001363 autoimmune Effects 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 208000019423 liver disease Diseases 0.000 claims 2
- 208000007903 liver failure Diseases 0.000 claims 2
- 231100000835 liver failure Toxicity 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 208000030159 metabolic disease Diseases 0.000 claims 2
- 238000012544 monitoring process Methods 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 230000001575 pathological effect Effects 0.000 claims 2
- 239000013610 patient sample Substances 0.000 claims 2
- 230000002062 proliferating effect Effects 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 230000001850 reproductive effect Effects 0.000 claims 2
- 208000023504 respiratory system disease Diseases 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 208000031295 Animal disease Diseases 0.000 claims 1
- 208000012239 Developmental disease Diseases 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 208000012902 Nervous system disease Diseases 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 230000004071 biological effect Effects 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 201000001119 neuropathy Diseases 0.000 claims 1
- 230000007823 neuropathy Effects 0.000 claims 1
- 208000033808 peripheral neuropathy Diseases 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0230006.9 | 2002-12-23 | ||
| GBGB0230006.9A GB0230006D0 (en) | 2002-12-23 | 2002-12-23 | Proteins |
| PCT/GB2003/005664 WO2004056983A2 (en) | 2002-12-23 | 2003-12-23 | Metalloprotease proteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006516888A JP2006516888A (ja) | 2006-07-13 |
| JP2006516888A5 true JP2006516888A5 (enExample) | 2007-02-22 |
| JP5053516B2 JP5053516B2 (ja) | 2012-10-17 |
Family
ID=9950313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004561689A Expired - Fee Related JP5053516B2 (ja) | 2002-12-23 | 2003-12-23 | メタロプロテアーゼタンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7557079B2 (enExample) |
| EP (1) | EP1583825B1 (enExample) |
| JP (1) | JP5053516B2 (enExample) |
| AT (1) | ATE526400T1 (enExample) |
| AU (1) | AU2003290342B2 (enExample) |
| CA (1) | CA2510066A1 (enExample) |
| ES (1) | ES2374392T3 (enExample) |
| GB (1) | GB0230006D0 (enExample) |
| IL (1) | IL169256A (enExample) |
| NO (1) | NO20053575L (enExample) |
| WO (1) | WO2004056983A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100183617A1 (en) * | 2005-02-23 | 2010-07-22 | University Of Virginia Patent Foundation | Compositions and methods for regulating sas1r |
| GB0921001D0 (en) | 2009-11-30 | 2010-01-13 | Aqua Bio Technology Asa | Products and uses |
| CN109957557B (zh) * | 2017-12-26 | 2023-01-06 | 广州市锐博生物科技有限公司 | Dna聚合酶及其制备方法 |
| CN114032252B (zh) * | 2021-11-01 | 2022-04-22 | 武汉爱博泰克生物科技有限公司 | 一种重组状态人源mmp-7蛋白的表达方法及应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030166902A1 (en) * | 2001-02-20 | 2003-09-04 | Yi Hu | Novel human protease and polynucleotides encoding the same |
| JP2004508021A (ja) | 2000-08-23 | 2004-03-18 | アプレラ コーポレーション | 単離ヒトプロテアーゼタンパク質、ヒトプロテアーゼタンパク質をコード化する核酸分子及びその使用 |
| CA2459140A1 (en) | 2001-09-14 | 2003-03-27 | Incyte Genomics, Inc. | Protein modification and maintenance molecules |
-
2002
- 2002-12-23 GB GBGB0230006.9A patent/GB0230006D0/en not_active Ceased
-
2003
- 2003-12-23 CA CA002510066A patent/CA2510066A1/en not_active Abandoned
- 2003-12-23 WO PCT/GB2003/005664 patent/WO2004056983A2/en not_active Ceased
- 2003-12-23 EP EP03782702A patent/EP1583825B1/en not_active Expired - Lifetime
- 2003-12-23 AU AU2003290342A patent/AU2003290342B2/en not_active Ceased
- 2003-12-23 JP JP2004561689A patent/JP5053516B2/ja not_active Expired - Fee Related
- 2003-12-23 ES ES03782702T patent/ES2374392T3/es not_active Expired - Lifetime
- 2003-12-23 US US10/539,847 patent/US7557079B2/en not_active Expired - Fee Related
- 2003-12-23 AT AT03782702T patent/ATE526400T1/de not_active IP Right Cessation
-
2005
- 2005-06-17 IL IL169256A patent/IL169256A/en not_active IP Right Cessation
- 2005-07-21 NO NO20053575A patent/NO20053575L/no not_active Application Discontinuation
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