JP2006516655A5 - - Google Patents
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- Publication number
- JP2006516655A5 JP2006516655A5 JP2006503409A JP2006503409A JP2006516655A5 JP 2006516655 A5 JP2006516655 A5 JP 2006516655A5 JP 2006503409 A JP2006503409 A JP 2006503409A JP 2006503409 A JP2006503409 A JP 2006503409A JP 2006516655 A5 JP2006516655 A5 JP 2006516655A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- cell
- protein
- toxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 claims 40
- 210000004027 cell Anatomy 0.000 claims 27
- 102000004169 proteins and genes Human genes 0.000 claims 10
- 108090000623 proteins and genes Proteins 0.000 claims 10
- 206010028980 Neoplasm Diseases 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 201000011510 cancer Diseases 0.000 claims 8
- 229940127089 cytotoxic agent Drugs 0.000 claims 8
- 239000003053 toxin Substances 0.000 claims 8
- 231100000765 toxin Toxicity 0.000 claims 8
- 239000002254 cytotoxic agent Substances 0.000 claims 6
- 231100000599 cytotoxic agent Toxicity 0.000 claims 6
- 229920001184 polypeptide Polymers 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 4
- 230000002401 inhibitory effect Effects 0.000 claims 4
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 230000012010 growth Effects 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 2
- 102000015833 Cystatin Human genes 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 239000002246 antineoplastic agent Substances 0.000 claims 2
- 230000003115 biocidal effect Effects 0.000 claims 2
- HXCHCVDVKSCDHU-LULTVBGHSA-N calicheamicin Chemical compound C1[C@H](OC)[C@@H](NCC)CO[C@H]1O[C@H]1[C@H](O[C@@H]2C\3=C(NC(=O)OC)C(=O)C[C@](C/3=C/CSSSC)(O)C#C\C=C/C#C2)O[C@H](C)[C@@H](NO[C@@H]2O[C@H](C)[C@@H](SC(=O)C=3C(=C(OC)C(O[C@H]4[C@@H]([C@H](OC)[C@@H](O)[C@H](C)O4)O)=C(I)C=3C)OC)[C@@H](O)C2)[C@@H]1O HXCHCVDVKSCDHU-LULTVBGHSA-N 0.000 claims 2
- 229930195731 calicheamicin Natural products 0.000 claims 2
- 230000030833 cell death Effects 0.000 claims 2
- 210000004978 chinese hamster ovary cell Anatomy 0.000 claims 2
- 108050004038 cystatin Proteins 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000003966 growth inhibitor Substances 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 230000001293 nucleolytic effect Effects 0.000 claims 2
- 238000001959 radiotherapy Methods 0.000 claims 2
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000010261 cell growth Effects 0.000 claims 1
- 238000001814 protein method Methods 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44539603P | 2003-02-05 | 2003-02-05 | |
| PCT/US2004/003607 WO2004071530A2 (en) | 2003-02-05 | 2004-02-05 | Identification of cellular polypeptides differentially expressed by tumor cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006516655A JP2006516655A (ja) | 2006-07-06 |
| JP2006516655A5 true JP2006516655A5 (enExample) | 2007-03-29 |
Family
ID=32869357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006503409A Withdrawn JP2006516655A (ja) | 2003-02-05 | 2004-02-05 | 腫瘍の診断と治療のための組成物と方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20040258696A1 (enExample) |
| EP (1) | EP1589997A2 (enExample) |
| JP (1) | JP2006516655A (enExample) |
| KR (1) | KR20050105459A (enExample) |
| AU (1) | AU2004211958A1 (enExample) |
| CA (1) | CA2515115A1 (enExample) |
| MX (1) | MXPA05008293A (enExample) |
| NZ (1) | NZ542206A (enExample) |
| WO (1) | WO2004071530A2 (enExample) |
| ZA (1) | ZA200506507B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105316405A (zh) * | 2003-07-17 | 2016-02-10 | 环太平洋生物技术有限公司 | 用于胃癌检测的标记物 |
| NZ568015A (en) | 2005-12-08 | 2012-03-30 | Medarex Inc | Human monoclonal antibodies to O8E |
| US20090011060A1 (en) * | 2007-07-06 | 2009-01-08 | Peter Koepke | Campsiandra angustifolia extract and methods of extracting and using such extract |
| US7879369B2 (en) | 2007-09-18 | 2011-02-01 | Selvamedica, Llc | Combretum laurifolium Mart. extract and methods of extracting and using such extract |
| US10260089B2 (en) | 2012-10-29 | 2019-04-16 | The Research Foundation Of The State University Of New York | Compositions and methods for recognition of RNA using triple helical peptide nucleic acids |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001016318A2 (en) * | 1999-09-01 | 2001-03-08 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6011012A (en) * | 1995-06-05 | 2000-01-04 | Human Genome Sciences, Inc. | Human cystatin E |
| WO2000052204A2 (en) * | 1999-02-22 | 2000-09-08 | Orntoft Torben F | Gene expression in bladder tumors |
| US6974667B2 (en) * | 2000-06-14 | 2005-12-13 | Gene Logic, Inc. | Gene expression profiles in liver cancer |
| JP2004502417A (ja) * | 2000-06-30 | 2004-01-29 | アムジェン インコーポレーテッド | Ｂ７様分子およびその使用 |
| EP1311662A2 (en) * | 2000-08-24 | 2003-05-21 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| US20030124579A1 (en) * | 2001-09-05 | 2003-07-03 | Eos Biotechnology, Inc. | Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer |
-
2004
- 2004-02-05 MX MXPA05008293A patent/MXPA05008293A/es not_active Application Discontinuation
- 2004-02-05 AU AU2004211958A patent/AU2004211958A1/en not_active Abandoned
- 2004-02-05 JP JP2006503409A patent/JP2006516655A/ja not_active Withdrawn
- 2004-02-05 NZ NZ542206A patent/NZ542206A/en unknown
- 2004-02-05 CA CA002515115A patent/CA2515115A1/en not_active Abandoned
- 2004-02-05 US US10/773,715 patent/US20040258696A1/en not_active Abandoned
- 2004-02-05 KR KR1020057014534A patent/KR20050105459A/ko not_active Withdrawn
- 2004-02-05 WO PCT/US2004/003607 patent/WO2004071530A2/en not_active Ceased
- 2004-02-05 EP EP04708670A patent/EP1589997A2/en not_active Withdrawn
-
2005
- 2005-08-15 ZA ZA200506507A patent/ZA200506507B/en unknown
-
2006
- 2006-01-18 US US11/335,394 patent/US20060147374A1/en not_active Abandoned
- 2006-01-23 US US11/338,537 patent/US20060140961A1/en not_active Abandoned
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