MXPA05008293A - Composiciones y metodos para el diagnostico y tratamiento de tumores. - Google Patents

Composiciones y metodos para el diagnostico y tratamiento de tumores.

Info

Publication number
MXPA05008293A
MXPA05008293A MXPA05008293A MXPA05008293A MXPA05008293A MX PA05008293 A MXPA05008293 A MX PA05008293A MX PA05008293 A MXPA05008293 A MX PA05008293A MX PA05008293 A MXPA05008293 A MX PA05008293A MX PA05008293 A MXPA05008293 A MX PA05008293A
Authority
MX
Mexico
Prior art keywords
compositions
tumor
diagnosis
treatment
methods
Prior art date
Application number
MXPA05008293A
Other languages
English (en)
Inventor
Zhang Zemin
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MXPA05008293A publication Critical patent/MXPA05008293A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion esta dirigida a la identificacion de varios polipeptidos celulares (y sus acidos nucleicos codificadores o fragmentos de los mimos) que son expresados a un grado mayor sobre la superficie de o por uno o mas tipos de celulas cancerigenas en comparacion con sobre la superficie de o por uno o mas tipo de celulas normales no cancerigenas. Alternativamente, dichos polipeptidos son expresados por celulas que producen y/o secretan polipeptidos que tienen un efecto potenciador o mejorador de crecimiento en celulas cancerigenas. De nuevo, alternativamente, dichos polipeptidos pueden ser no sobreexpresadas por celulas tumorales en comparacion con celulas normales del mismo tipo de tejido pero si pueden expresarse especificamente tanto por las celulas tumorales y como por las celulas normales de solo un numero unico o muy limitado de tipos de tejido (de preferencia tejidos que no son esenciales para la vida, por ejemplo, la prostata, etc.).
MXPA05008293A 2003-02-05 2004-02-05 Composiciones y metodos para el diagnostico y tratamiento de tumores. MXPA05008293A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44539603P 2003-02-05 2003-02-05
PCT/US2004/003607 WO2004071530A2 (en) 2003-02-05 2004-02-05 Identification of cellular polypeptides differentially expressed by tumor cells

Publications (1)

Publication Number Publication Date
MXPA05008293A true MXPA05008293A (es) 2005-10-18

Family

ID=32869357

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05008293A MXPA05008293A (es) 2003-02-05 2004-02-05 Composiciones y metodos para el diagnostico y tratamiento de tumores.

Country Status (10)

Country Link
US (3) US20040258696A1 (es)
EP (1) EP1589997A2 (es)
JP (1) JP2006516655A (es)
KR (1) KR20050105459A (es)
AU (1) AU2004211958A1 (es)
CA (1) CA2515115A1 (es)
MX (1) MXPA05008293A (es)
NZ (1) NZ542206A (es)
WO (1) WO2004071530A2 (es)
ZA (1) ZA200506507B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2532722C (en) * 2003-07-17 2016-10-04 Pacific Edge Biotechnology, Ltd. Cystatin sn (cst1) and other markers for detection of gastric cancer
NZ568015A (en) 2005-12-08 2012-03-30 Medarex Inc Human monoclonal antibodies to O8E
US20090011060A1 (en) * 2007-07-06 2009-01-08 Peter Koepke Campsiandra angustifolia extract and methods of extracting and using such extract
US7879369B2 (en) 2007-09-18 2011-02-01 Selvamedica, Llc Combretum laurifolium Mart. extract and methods of extracting and using such extract
US10260089B2 (en) 2012-10-29 2019-04-16 The Research Foundation Of The State University Of New York Compositions and methods for recognition of RNA using triple helical peptide nucleic acids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011012A (en) * 1995-06-05 2000-01-04 Human Genome Sciences, Inc. Human cystatin E
AU3316600A (en) * 1999-02-22 2000-09-21 Torben F. Orntoft Gene expression in bladder tumors
CA2380355A1 (en) * 1999-09-01 2001-03-08 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6974667B2 (en) * 2000-06-14 2005-12-13 Gene Logic, Inc. Gene expression profiles in liver cancer
MXPA02012749A (es) * 2000-06-30 2003-10-06 Amgen Inc Moleculas semejantes a b7 y sus usos.
EP1311662A2 (en) * 2000-08-24 2003-05-21 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US20030124579A1 (en) * 2001-09-05 2003-07-03 Eos Biotechnology, Inc. Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer

Also Published As

Publication number Publication date
US20040258696A1 (en) 2004-12-23
WO2004071530A3 (en) 2005-05-12
JP2006516655A (ja) 2006-07-06
AU2004211958A1 (en) 2004-08-26
US20060147374A1 (en) 2006-07-06
ZA200506507B (en) 2006-12-27
KR20050105459A (ko) 2005-11-04
NZ542206A (en) 2008-04-30
US20060140961A1 (en) 2006-06-29
CA2515115A1 (en) 2004-08-26
WO2004071530A2 (en) 2004-08-26
EP1589997A2 (en) 2005-11-02

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal