JP2006516098A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006516098A5 JP2006516098A5 JP2004562249A JP2004562249A JP2006516098A5 JP 2006516098 A5 JP2006516098 A5 JP 2006516098A5 JP 2004562249 A JP2004562249 A JP 2004562249A JP 2004562249 A JP2004562249 A JP 2004562249A JP 2006516098 A5 JP2006516098 A5 JP 2006516098A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- acid sequence
- iia1
- amino acid
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 150000007523 nucleic acids Chemical group 0.000 description 2
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42974302P | 2002-11-26 | 2002-11-26 | |
| US60/429,743 | 2002-11-26 | ||
| PCT/US2003/038172 WO2004056308A2 (en) | 2002-11-26 | 2003-11-26 | CHIMERIC AND HUMANIZED ANTIBODIES TO α5β1 INTEGRIN THAT MODULATE ANGIOGENESIS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011000939A Division JP2011120593A (ja) | 2002-11-26 | 2011-01-06 | 新脈管形成を調節するα5β1インテグリンへのキメラ及びヒト化抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006516098A JP2006516098A (ja) | 2006-06-22 |
| JP2006516098A5 true JP2006516098A5 (enExample) | 2006-11-02 |
| JP4741242B2 JP4741242B2 (ja) | 2011-08-03 |
Family
ID=32681936
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004562249A Expired - Lifetime JP4741242B2 (ja) | 2002-11-26 | 2003-11-26 | 新脈管形成を調節するα5β1インテグリンへのキメラ及びヒト化抗体 |
| JP2011000939A Pending JP2011120593A (ja) | 2002-11-26 | 2011-01-06 | 新脈管形成を調節するα5β1インテグリンへのキメラ及びヒト化抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011000939A Pending JP2011120593A (ja) | 2002-11-26 | 2011-01-06 | 新脈管形成を調節するα5β1インテグリンへのキメラ及びヒト化抗体 |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP1575516B1 (enExample) |
| JP (2) | JP4741242B2 (enExample) |
| KR (2) | KR20110140143A (enExample) |
| CN (1) | CN100369930C (enExample) |
| AU (1) | AU2003298783B2 (enExample) |
| BR (1) | BR0316670A (enExample) |
| CA (1) | CA2507099C (enExample) |
| ES (1) | ES2387985T3 (enExample) |
| MX (1) | MXPA05005558A (enExample) |
| NO (1) | NO20053101L (enExample) |
| NZ (1) | NZ540562A (enExample) |
| RU (1) | RU2346701C2 (enExample) |
| WO (1) | WO2004056308A2 (enExample) |
| ZA (1) | ZA200505114B (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY147019A (en) | 2002-03-13 | 2012-10-15 | Biogen Idec Inc | Anti-alpha v beta 6 antibodies |
| US7276589B2 (en) | 2002-11-26 | 2007-10-02 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
| EP1755659B1 (en) | 2004-03-24 | 2011-11-02 | Abbott Biotherapeutics Corp. | Use of anti-alpha5beta1 antibodies to inhibit cancer cell proliferation |
| US20060008415A1 (en) * | 2004-06-25 | 2006-01-12 | Protein Design Labs, Inc. | Stable liquid and lyophilized formulation of proteins |
| CN102875681A (zh) * | 2005-07-08 | 2013-01-16 | 拜奥根Idec马萨诸塞公司 | 抗-αvβ6抗体及其用途 |
| CA2646611A1 (en) * | 2006-03-21 | 2008-05-22 | Genentech, Inc. | Combinatorial therapy |
| CN101448858B (zh) * | 2006-03-21 | 2013-06-12 | 健泰科生物技术公司 | 牵涉α5β1拮抗剂的联合疗法 |
| CA2652886A1 (en) * | 2006-05-24 | 2007-11-29 | Bayer Schering Pharma Aktiengesellschaft | High affinity human and humanized anti-.alpha.5.beta.1 integrin function blocking antibodies with reduced immunogenicity |
| CN101563105B (zh) | 2006-07-10 | 2013-01-23 | 拜奥根Idec马萨诸塞公司 | 用于抑制smad4-缺陷癌症的组合物和方法 |
| EP2526967A1 (en) * | 2007-07-17 | 2012-11-28 | Merck Patent GmbH | Engineered anti-alpha v-integrin hybrid antibodies |
| WO2009018226A2 (en) * | 2007-07-27 | 2009-02-05 | Facet Biotech Corporation | Pharmaceutical combinations comprising a tyrosine kinase inhibitor and an antibody against integrin alpha 1 beta 5 (cd49e) |
| AR066170A1 (es) * | 2007-09-26 | 2009-07-29 | Genentech Inc | Anti integrina alfa 5 beta 1 |
| AU2009212442C1 (en) | 2008-02-05 | 2014-07-17 | Bristol-Myers Squibb Company | Alpha 5 - beta 1 antibodies and their uses |
| KR101054725B1 (ko) * | 2008-07-31 | 2011-08-05 | 재단법인서울대학교산학협력재단 | 세포외기질 성분을 함유하는 노화조절용 조성물 및 이를이용한 노화세포의 노화조절방법 |
| CA2748161A1 (en) * | 2008-12-23 | 2010-07-01 | Astrazeneca Ab | Targeted binding agents directed to .alpha.5.beta.1 and uses thereof |
| US20120114667A1 (en) | 2008-12-23 | 2012-05-10 | Medimmune Limited | TARGETED BINDING AGENTS DIRECTED TO a5BETA1 AND USES THEREOF |
| WO2010095031A2 (en) * | 2009-02-23 | 2010-08-26 | Glenmark Pharmaceuticals S.A. | Humanized antibodies that bind to cd19 and their uses |
| MA33210B1 (fr) * | 2009-03-25 | 2012-04-02 | Genentech Inc | Nouveaux anticorps anti-a5b1 et leurs utilisations |
| CN101638429B (zh) * | 2009-08-28 | 2012-01-25 | 南方医科大学 | 一种特异性识别细胞表面整合素α3β1的小分子肽 |
| CA2784278C (en) * | 2009-12-18 | 2019-02-26 | Novartis Ag | Wash solution and method for affinity chromatography |
| RU2015102845A (ru) * | 2010-02-23 | 2015-06-10 | Санофи | АНТИТЕЛА К ИНТЕГРИНУ α2 И ИХ ПРИМЕНЕНИЯ |
| SG192667A1 (en) | 2011-02-11 | 2013-09-30 | Merck Patent Gmbh | Anti-alpha-v integrin antibody for the treatment of prostate cancer |
| EP2834273B1 (en) * | 2012-04-05 | 2018-08-22 | F.Hoffmann-La Roche Ag | Bispecific antibodies against human tweak and human il17 and uses thereof |
| EP3530284B1 (en) | 2012-12-26 | 2023-10-25 | OncoSynergy, Inc. | Anti-integrin beta1 antibody compositions and methods of use thereof |
| US10035860B2 (en) | 2013-03-15 | 2018-07-31 | Biogen Ma Inc. | Anti-alpha V beta 6 antibodies and uses thereof |
| US10035859B2 (en) | 2013-03-15 | 2018-07-31 | Biogen Ma Inc. | Anti-alpha V beta 6 antibodies and uses thereof |
| JP7414529B2 (ja) | 2017-06-07 | 2024-01-16 | シファメド・ホールディングス・エルエルシー | 血管内流体移動デバイス、システム、および使用方法 |
| EP3710076B1 (en) | 2017-11-13 | 2023-12-27 | Shifamed Holdings, LLC | Intravascular fluid movement devices, systems, and methods of use |
| EP4085965A1 (en) | 2018-02-01 | 2022-11-09 | Shifamed Holdings, LLC | Intravascular blood pumps and methods of use and manufacture |
| WO2020028537A1 (en) | 2018-07-31 | 2020-02-06 | Shifamed Holdings, Llc | Intravascaular blood pumps and methods of use |
| US12220570B2 (en) | 2018-10-05 | 2025-02-11 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
| WO2021011473A1 (en) | 2019-07-12 | 2021-01-21 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
| WO2021016372A1 (en) | 2019-07-22 | 2021-01-28 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
| US12465748B2 (en) | 2019-08-07 | 2025-11-11 | Supira Medical, Inc. | Catheter blood pumps and collapsible pump housings |
| WO2021062260A1 (en) | 2019-09-25 | 2021-04-01 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible blood conduits |
| US11724089B2 (en) | 2019-09-25 | 2023-08-15 | Shifamed Holdings, Llc | Intravascular blood pump systems and methods of use and control thereof |
| US12102815B2 (en) | 2019-09-25 | 2024-10-01 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible pump housings |
| US12409310B2 (en) | 2019-12-11 | 2025-09-09 | Shifamed Holdings, Llc | Descending aorta and vena cava blood pumps |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4704366A (en) * | 1984-06-22 | 1987-11-03 | Bio-Rad Laboratories, Inc. | Process for binding IgG to protein A |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| US5618920A (en) | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4801687A (en) * | 1986-10-27 | 1989-01-31 | Bioprobe International, Inc. | Monoclonal antibody purification process using protein A |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| WO1992015683A1 (en) | 1991-03-06 | 1992-09-17 | MERCK Patent Gesellschaft mit beschränkter Haftung | Humanized and chimeric monoclonal antibodies |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| KR100252547B1 (ko) | 1991-09-05 | 2000-09-01 | 프레드 마리얀스키 | 폴리-또는 올리고누클레오티드의 세포로의 표적화된 전달 |
| CA2078539C (en) | 1991-09-18 | 2005-08-02 | Kenya Shitara | Process for producing humanized chimera antibody |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| GB9125979D0 (en) | 1991-12-06 | 1992-02-05 | Wellcome Found | Antibody |
| AU684041B2 (en) | 1992-02-19 | 1997-12-04 | Schering Corporation | Cloning and expression of humanized monoclonal antibodies against human interleukin-4 |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| WO1995022618A1 (en) | 1994-02-22 | 1995-08-24 | Dana-Farber Cancer Institute | Nucleic acid delivery system, method of synthesis and uses thereof |
| US5705154A (en) | 1995-03-08 | 1998-01-06 | Schering Corporation | Humanized monoclonal antibodies against human interleukin-4 |
| US5961955A (en) | 1997-06-03 | 1999-10-05 | Coulter Pharmaceutical, Inc. | Radioprotectant for peptides labeled with radioisotope |
| AU746662B2 (en) * | 1998-05-08 | 2002-05-02 | Regents Of The University Of California, The | Methods for detecting and inhibiting angiogenesis |
| US6852318B1 (en) * | 1998-05-08 | 2005-02-08 | The Regents Of The University Of California | Methods for detecting and inhibiting angiogenesis |
| US7285268B2 (en) * | 2002-11-26 | 2007-10-23 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
| US9111624B2 (en) | 2013-03-22 | 2015-08-18 | Katsuyuki Fujita | Semiconductor memory device |
-
2003
- 2003-11-26 KR KR1020117029575A patent/KR20110140143A/ko not_active Abandoned
- 2003-11-26 JP JP2004562249A patent/JP4741242B2/ja not_active Expired - Lifetime
- 2003-11-26 MX MXPA05005558A patent/MXPA05005558A/es active IP Right Grant
- 2003-11-26 RU RU2005120019/15A patent/RU2346701C2/ru active
- 2003-11-26 CN CNB2003801091807A patent/CN100369930C/zh not_active Expired - Lifetime
- 2003-11-26 NZ NZ540562A patent/NZ540562A/en not_active IP Right Cessation
- 2003-11-26 WO PCT/US2003/038172 patent/WO2004056308A2/en not_active Ceased
- 2003-11-26 CA CA2507099A patent/CA2507099C/en not_active Expired - Lifetime
- 2003-11-26 ES ES03796541T patent/ES2387985T3/es not_active Expired - Lifetime
- 2003-11-26 EP EP03796541A patent/EP1575516B1/en not_active Expired - Lifetime
- 2003-11-26 AU AU2003298783A patent/AU2003298783B2/en not_active Expired
- 2003-11-26 EP EP10012456A patent/EP2351583A1/en not_active Withdrawn
- 2003-11-26 KR KR1020057009577A patent/KR20050089151A/ko not_active Abandoned
- 2003-11-26 BR BR0316670-8A patent/BR0316670A/pt not_active IP Right Cessation
-
2005
- 2005-06-23 ZA ZA200505114A patent/ZA200505114B/en unknown
- 2005-06-24 NO NO20053101A patent/NO20053101L/no not_active Application Discontinuation
-
2011
- 2011-01-06 JP JP2011000939A patent/JP2011120593A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006516098A5 (enExample) | ||
| JP2007508034A5 (enExample) | ||
| JP2003515323A5 (enExample) | ||
| IL164966A0 (en) | 3?-Ä2Z)-Ä1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylideneÜhydrazinoÜ-2'-hydroxy-Ä1,1'-biphenylÜ-3-carboxylic acid bis-(monoethanolamine) | |
| WO2003093296A3 (en) | Kinase anchor protein muteins, peptides thereof, and related methods | |
| WO2003093306A3 (en) | Nucleic acids and proteins from streptococcus groups a & b | |
| EE200300100A (et) | Polüpeptiid, selle kodeerivat nukleotiidjärjestust sisaldav nukleiinhape, vektor ja peremeesrakk, meetod polüpeptiidi valmistamiseks ning farmatseutiline kompositsioon | |
| JP2005530695A5 (enExample) | ||
| JP2005529611A5 (enExample) | ||
| AU2003304180A8 (en) | Growth arrest specific gene 6 peptides, antibodies, compositions, methods and uses | |
| CA2361987A1 (en) | Goodpasture antigen binding protein | |
| IS7609A (is) | 2,5-tvíútskipt 3-merkaptópentansýra | |
| JP2003284553A5 (enExample) | ||
| JP2006515984A5 (enExample) | ||
| AU2003223923A1 (en) | Peptide nucleic acid conjugates with transporter peptides | |
| JP2005535281A5 (enExample) | ||
| PL379564A1 (pl) | Kwasy nukleinowe, proteiny i przeciwciała BTL-II | |
| JP2008545719A5 (enExample) | ||
| JP2006510360A5 (enExample) | ||
| JPH10210974A5 (enExample) | ||
| ZA200100332B (en) | Novel nucleotide sequences coding for the ptsH gene. | |
| WO2001087932A3 (en) | Seven transmembrane proteins and polynucleotides encoding the same | |
| AU2003216772A1 (en) | Nucleic acid molecule encoding a variant ddah 1 protein and uses thereof | |
| RU2002110800A (ru) | Искусственный белок-иммуноген TCI, содержащий множественные CTL-эпитопы основных антигенов ВИЧ-1, искусственный ген TCI, кодирующий полиэпитопный белок-иммуноген TCI | |
| JP2004500045A5 (enExample) |