JP2006516098A5 - - Google Patents
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- Publication number
- JP2006516098A5 JP2006516098A5 JP2004562249A JP2004562249A JP2006516098A5 JP 2006516098 A5 JP2006516098 A5 JP 2006516098A5 JP 2004562249 A JP2004562249 A JP 2004562249A JP 2004562249 A JP2004562249 A JP 2004562249A JP 2006516098 A5 JP2006516098 A5 JP 2006516098A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- acid sequence
- iia1
- amino acid
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 150000007523 nucleic acids Chemical group 0.000 description 2
Images
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42974302P | 2002-11-26 | 2002-11-26 | |
| US60/429,743 | 2002-11-26 | ||
| PCT/US2003/038172 WO2004056308A2 (en) | 2002-11-26 | 2003-11-26 | CHIMERIC AND HUMANIZED ANTIBODIES TO α5β1 INTEGRIN THAT MODULATE ANGIOGENESIS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011000939A Division JP2011120593A (ja) | 2002-11-26 | 2011-01-06 | 新脈管形成を調節するα5β1インテグリンへのキメラ及びヒト化抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006516098A JP2006516098A (ja) | 2006-06-22 |
| JP2006516098A5 true JP2006516098A5 (enExample) | 2006-11-02 |
| JP4741242B2 JP4741242B2 (ja) | 2011-08-03 |
Family
ID=32681936
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004562249A Expired - Lifetime JP4741242B2 (ja) | 2002-11-26 | 2003-11-26 | 新脈管形成を調節するα5β1インテグリンへのキメラ及びヒト化抗体 |
| JP2011000939A Pending JP2011120593A (ja) | 2002-11-26 | 2011-01-06 | 新脈管形成を調節するα5β1インテグリンへのキメラ及びヒト化抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011000939A Pending JP2011120593A (ja) | 2002-11-26 | 2011-01-06 | 新脈管形成を調節するα5β1インテグリンへのキメラ及びヒト化抗体 |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP1575516B1 (enExample) |
| JP (2) | JP4741242B2 (enExample) |
| KR (2) | KR20050089151A (enExample) |
| CN (1) | CN100369930C (enExample) |
| AU (1) | AU2003298783B2 (enExample) |
| BR (1) | BR0316670A (enExample) |
| CA (1) | CA2507099C (enExample) |
| ES (1) | ES2387985T3 (enExample) |
| MX (1) | MXPA05005558A (enExample) |
| NO (1) | NO20053101L (enExample) |
| NZ (1) | NZ540562A (enExample) |
| RU (1) | RU2346701C2 (enExample) |
| WO (1) | WO2004056308A2 (enExample) |
| ZA (1) | ZA200505114B (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY147019A (en) | 2002-03-13 | 2012-10-15 | Biogen Idec Inc | Anti-alpha v beta 6 antibodies |
| US7276589B2 (en) | 2002-11-26 | 2007-10-02 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
| ATE531388T1 (de) * | 2004-03-24 | 2011-11-15 | Abbott Biotherapeutics Corp | Verwendung von anti-alpha5beta1-antikörpern zur hemmung der krebszellproliferation |
| US20060008415A1 (en) * | 2004-06-25 | 2006-01-12 | Protein Design Labs, Inc. | Stable liquid and lyophilized formulation of proteins |
| CN102875681A (zh) * | 2005-07-08 | 2013-01-16 | 拜奥根Idec马萨诸塞公司 | 抗-αvβ6抗体及其用途 |
| ZA200807754B (en) * | 2006-03-21 | 2009-12-30 | Genentech Inc | Combinatorial therapy involving alpha5beta1 antagonists |
| AR060040A1 (es) * | 2006-03-21 | 2008-05-21 | Genentech Inc | Antagonistas de vefg y de alfa5 beta 1 |
| EP2032605A2 (en) * | 2006-05-24 | 2009-03-11 | Bayer Schering Pharma Aktiengesellschaft | HIGH AFFINITY HUMAN AND HUMANIZED ANTI-alpha5ß1 INTEGRIN FUNCTION BLOCKING ANTIBODIES WITH REDUCED IMMUNOGENICITY |
| BRPI0714381A2 (pt) | 2006-07-10 | 2013-03-05 | Biogen Idec Inc | composiÇÕes e mÉtodos para inibir crescimento de cÂnceres deficientes em smad4 |
| CN101687039B (zh) * | 2007-07-17 | 2014-04-16 | 默克专利有限公司 | 工程化抗αν-整联蛋白杂合抗体 |
| AU2008282331A1 (en) * | 2007-07-27 | 2009-02-05 | Facet Biotech Corporation | Pharmaceutical combinations comprising a tyrosine kinase inhibitor and an antibody against integrin alpha 1 beta 5 (CD49E) |
| AR066170A1 (es) * | 2007-09-26 | 2009-07-29 | Genentech Inc | Anti integrina alfa 5 beta 1 |
| WO2009100110A1 (en) | 2008-02-05 | 2009-08-13 | Medarex, Inc. | Alpha 5 - beta 1 antibodies and their uses |
| KR101054725B1 (ko) * | 2008-07-31 | 2011-08-05 | 재단법인서울대학교산학협력재단 | 세포외기질 성분을 함유하는 노화조절용 조성물 및 이를이용한 노화세포의 노화조절방법 |
| CA2748161A1 (en) * | 2008-12-23 | 2010-07-01 | Astrazeneca Ab | Targeted binding agents directed to .alpha.5.beta.1 and uses thereof |
| EP2379595A2 (en) | 2008-12-23 | 2011-10-26 | AstraZeneca AB | Targeted binding agents directed to 5 1 and uses thereof |
| CA2753158A1 (en) * | 2009-02-23 | 2010-08-26 | Glenmark Pharmaceuticals S.A. | Humanized antibodies that bind to cd19 and their uses |
| CN103755808B (zh) * | 2009-03-25 | 2016-02-10 | 霍夫曼-拉罗奇有限公司 | 抗-α5β1抗体及其应用 |
| CN101638429B (zh) * | 2009-08-28 | 2012-01-25 | 南方医科大学 | 一种特异性识别细胞表面整合素α3β1的小分子肽 |
| BR112012014937B1 (pt) * | 2009-12-18 | 2021-01-19 | Novartis Ag | método de produção de um anticorpo, fragmento de anticorpo ou proteína de fusão fc purificada usando uma matriz de cromatografia de afinidade |
| RU2545401C2 (ru) * | 2010-02-23 | 2015-03-27 | Санофи | Антитела к интегрину альфа-2 и их применения |
| ES2683347T3 (es) | 2011-02-11 | 2018-09-26 | Merck Patent Gmbh | Anticuerpo anti-integrina alfa-v para el tratamiento de cáncer de próstata |
| KR101674784B1 (ko) * | 2012-04-05 | 2016-11-09 | 에프. 호프만-라 로슈 아게 | 인간 tweak 및 인간 il17에 대한 이중특이적 항체 및 이의 용도 |
| RU2681994C2 (ru) * | 2012-12-26 | 2019-03-14 | Онкосинерджи, Инк. | КОМПОЗИЦИИ АНТИТЕЛА К ИНТЕГРИНУ β1 И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| WO2014143739A2 (en) | 2013-03-15 | 2014-09-18 | Biogen Idec Ma Inc. | Anti-alpha v beta 6 antibodies and uses thereof |
| US10035859B2 (en) | 2013-03-15 | 2018-07-31 | Biogen Ma Inc. | Anti-alpha V beta 6 antibodies and uses thereof |
| CN110944689B (zh) | 2017-06-07 | 2022-12-09 | 施菲姆德控股有限责任公司 | 血管内流体运动设备、系统和使用方法 |
| WO2019094963A1 (en) | 2017-11-13 | 2019-05-16 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| WO2019152875A1 (en) | 2018-02-01 | 2019-08-08 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US12161857B2 (en) | 2018-07-31 | 2024-12-10 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
| WO2020073047A1 (en) | 2018-10-05 | 2020-04-09 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
| US11964145B2 (en) | 2019-07-12 | 2024-04-23 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
| WO2021016372A1 (en) | 2019-07-22 | 2021-01-28 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
| EP4010046B1 (en) | 2019-08-07 | 2026-07-15 | Supira Medical, Inc. | Catheter blood pumps and collapsible pump housings |
| WO2021062270A1 (en) | 2019-09-25 | 2021-04-01 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible pump housings |
| EP4034192B1 (en) | 2019-09-25 | 2025-12-24 | Supira Medical, Inc. | Intravascular blood pump systems and methods of use and control thereof |
| EP4782050A1 (en) | 2019-09-25 | 2026-07-29 | Supira Medical, Inc. | Catheter blood pumps and collapsible blood conduits |
| EP4072650A4 (en) | 2019-12-11 | 2024-01-10 | Shifamed Holdings, LLC | Descending aorta and vena cava blood pumps |
| WO2021127503A1 (en) | 2019-12-19 | 2021-06-24 | Shifamed Holdings, Llc | Intravascular blood pumps, motors, and fluid control |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4704366A (en) * | 1984-06-22 | 1987-11-03 | Bio-Rad Laboratories, Inc. | Process for binding IgG to protein A |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| US5618920A (en) | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US4801687A (en) * | 1986-10-27 | 1989-01-31 | Bioprobe International, Inc. | Monoclonal antibody purification process using protein A |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| AU658396B2 (en) | 1991-03-06 | 1995-04-13 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Humanized and chimeric monoclonal antibodies |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| KR100252547B1 (ko) | 1991-09-05 | 2000-09-01 | 프레드 마리얀스키 | 폴리-또는 올리고누클레오티드의 세포로의 표적화된 전달 |
| CA2078539C (en) | 1991-09-18 | 2005-08-02 | Kenya Shitara | Process for producing humanized chimera antibody |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| GB9125979D0 (en) | 1991-12-06 | 1992-02-05 | Wellcome Found | Antibody |
| US5863537A (en) | 1992-02-19 | 1999-01-26 | Schering Corporation | Humanized monoclonal antibodies against human interleukin-4 |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| JPH10501681A (ja) | 1994-02-22 | 1998-02-17 | ダナ−ファーバー キャンサー インスティチュート | 核酸送達システムならびにその合成および使用方法 |
| US5705154A (en) | 1995-03-08 | 1998-01-06 | Schering Corporation | Humanized monoclonal antibodies against human interleukin-4 |
| US5961955A (en) | 1997-06-03 | 1999-10-05 | Coulter Pharmaceutical, Inc. | Radioprotectant for peptides labeled with radioisotope |
| WO1999058139A2 (en) * | 1998-05-08 | 1999-11-18 | The Regents Of The University Of California | Methods for detecting and inhibiting angiogenesis |
| US6852318B1 (en) * | 1998-05-08 | 2005-02-08 | The Regents Of The University Of California | Methods for detecting and inhibiting angiogenesis |
| US7285268B2 (en) * | 2002-11-26 | 2007-10-23 | Pdl Biopharma, Inc. | Chimeric and humanized antibodies to α5β1 integrin that modulate angiogenesis |
| US9111624B2 (en) | 2013-03-22 | 2015-08-18 | Katsuyuki Fujita | Semiconductor memory device |
-
2003
- 2003-11-26 MX MXPA05005558A patent/MXPA05005558A/es active IP Right Grant
- 2003-11-26 NZ NZ540562A patent/NZ540562A/en not_active IP Right Cessation
- 2003-11-26 EP EP03796541A patent/EP1575516B1/en not_active Expired - Lifetime
- 2003-11-26 WO PCT/US2003/038172 patent/WO2004056308A2/en not_active Ceased
- 2003-11-26 EP EP10012456A patent/EP2351583A1/en not_active Withdrawn
- 2003-11-26 AU AU2003298783A patent/AU2003298783B2/en not_active Expired
- 2003-11-26 BR BR0316670-8A patent/BR0316670A/pt not_active IP Right Cessation
- 2003-11-26 RU RU2005120019/15A patent/RU2346701C2/ru active
- 2003-11-26 CN CNB2003801091807A patent/CN100369930C/zh not_active Expired - Lifetime
- 2003-11-26 KR KR1020057009577A patent/KR20050089151A/ko not_active Abandoned
- 2003-11-26 CA CA2507099A patent/CA2507099C/en not_active Expired - Lifetime
- 2003-11-26 JP JP2004562249A patent/JP4741242B2/ja not_active Expired - Lifetime
- 2003-11-26 KR KR1020117029575A patent/KR20110140143A/ko not_active Abandoned
- 2003-11-26 ES ES03796541T patent/ES2387985T3/es not_active Expired - Lifetime
-
2005
- 2005-06-23 ZA ZA200505114A patent/ZA200505114B/en unknown
- 2005-06-24 NO NO20053101A patent/NO20053101L/no not_active Application Discontinuation
-
2011
- 2011-01-06 JP JP2011000939A patent/JP2011120593A/ja active Pending
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