JP2006516047A - マグネットクランプを備えた経皮アッセイ - Google Patents

マグネットクランプを備えた経皮アッセイ Download PDF

Info

Publication number
JP2006516047A
JP2006516047A JP2004548548A JP2004548548A JP2006516047A JP 2006516047 A JP2006516047 A JP 2006516047A JP 2004548548 A JP2004548548 A JP 2004548548A JP 2004548548 A JP2004548548 A JP 2004548548A JP 2006516047 A JP2006516047 A JP 2006516047A
Authority
JP
Japan
Prior art keywords
sample
assay device
transdermal
magnet
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004548548A
Other languages
English (en)
Japanese (ja)
Inventor
シマ,マイケル,ジェー.
チェン,ホンミン
ギョリ,ジェー.,リチャード
リーモ,アンソニー,ヴィー.
モナグル,ジュリー
ゴンザレス−ザガスティ,ジェイバー,ピー.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transform Pharmaceuticals Inc
Original Assignee
Transform Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/282,505 external-priority patent/US6852526B2/en
Application filed by Transform Pharmaceuticals Inc filed Critical Transform Pharmaceuticals Inc
Publication of JP2006516047A publication Critical patent/JP2006516047A/ja
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255Multi-well filtration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/08Investigating permeability, pore-volume, or surface area of porous materials
    • G01N15/0806Details, e.g. sample holders, mounting samples for testing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0609Holders integrated in container to position an object
    • B01L2300/0618Holders integrated in container to position an object for removable separation walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2004548548A 2002-10-28 2003-10-28 マグネットクランプを備えた経皮アッセイ Pending JP2006516047A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/282,505 US6852526B2 (en) 2000-07-14 2002-10-28 Transdermal assay with magnetic clamp
PCT/US2003/034262 WO2004040006A1 (en) 2002-10-28 2003-10-28 Transdermal assay with magnetic clamp

Publications (1)

Publication Number Publication Date
JP2006516047A true JP2006516047A (ja) 2006-06-15

Family

ID=34312013

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004548548A Pending JP2006516047A (ja) 2002-10-28 2003-10-28 マグネットクランプを備えた経皮アッセイ

Country Status (4)

Country Link
EP (1) EP1556501A4 (de)
JP (1) JP2006516047A (de)
AU (1) AU2003286736A1 (de)
WO (1) WO2004040006A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011500198A (ja) * 2007-10-17 2011-01-06 トランスファーマ メディカル リミテッド 溶出速度の検証
JP2011133417A (ja) * 2009-12-25 2011-07-07 Lvmc Inc 活性酸素種濃度測定用センサーを用いた皮膚化粧料用抗酸化物質の簡便なスクリーニング方法
JP2015219114A (ja) * 2014-05-19 2015-12-07 株式会社イントロテック 透過性試験装置

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005057031B4 (de) * 2005-11-25 2011-04-21 Innovent E.V. Technologieentwicklung Vorrichtung für Permeations-oder Stoffdurchgangsuntersuchungen
FR3100334B1 (fr) * 2019-09-03 2021-07-30 Fabre Pierre Dermo Cosmetique Dispositif pour la détermination automatisée du passage percutané et de la métabolisation d’une substance

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3551554A (en) 1968-08-16 1970-12-29 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active agents with dmso
US4317726A (en) * 1981-02-12 1982-03-02 The United States Of America As Represented By The Secretary Of The Army Microbial filter assembly
US4468321A (en) * 1982-03-12 1984-08-28 Gelman Sciences Inc. Filter device with magnetic filter clamp
US4537776A (en) 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4605670A (en) 1984-02-01 1986-08-12 Nitto Electric Industrial Co., Ltd. Method for percutaneously administering metoclopramide
US4863970A (en) 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US5006342A (en) 1986-12-22 1991-04-09 Cygnus Corporation Resilient transdermal drug delivery device
US4820720A (en) 1987-08-24 1989-04-11 Alza Corporation Transdermal drug composition with dual permeation enhancers
US4973468A (en) 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
US5306467A (en) * 1993-02-17 1994-04-26 Hamilton-Thorn Research Apparatus for measurement of cell concentration in a biological sample employing a magnetic slide loading apparatus
CA2174140C (en) 1993-10-28 2004-04-06 Kenneth L. Beattie Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
US5490415A (en) * 1994-04-15 1996-02-13 Pharmetrix Corporation Diffusion test apparatus and method
US5695998A (en) * 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US5962250A (en) * 1997-10-28 1999-10-05 Glaxo Group Limited Split multi-well plate and methods
DE19943443A1 (de) * 1999-09-11 2001-04-12 Inst Mikrotechnik Mainz Gmbh Vorrichtung und Verfahren zur Planarisierung von Titerplatten in Screening- und Synthesesystemen
WO2002006518A1 (en) * 2000-07-14 2002-01-24 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
WO2002016941A2 (en) * 2000-08-23 2002-02-28 The Regents Of The University Of California A combinatorial method for rapid screening of drug delivery formulations
DE10106996C2 (de) * 2001-02-15 2003-04-24 Merck Patent Gmbh Einrichtung zur Verbindung von Mikrokomponenten

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011500198A (ja) * 2007-10-17 2011-01-06 トランスファーマ メディカル リミテッド 溶出速度の検証
JP2011133417A (ja) * 2009-12-25 2011-07-07 Lvmc Inc 活性酸素種濃度測定用センサーを用いた皮膚化粧料用抗酸化物質の簡便なスクリーニング方法
JP2015219114A (ja) * 2014-05-19 2015-12-07 株式会社イントロテック 透過性試験装置

Also Published As

Publication number Publication date
EP1556501A4 (de) 2009-04-08
AU2003286736A1 (en) 2004-05-25
EP1556501A1 (de) 2005-07-27
WO2004040006A1 (en) 2004-05-13

Similar Documents

Publication Publication Date Title
US6852526B2 (en) Transdermal assay with magnetic clamp
US6758099B2 (en) System and method for optimizing tissue barrier transfer of compounds
AU2001277887A1 (en) System and method for optimizing tissue barrier transfer of compounds
US8277762B2 (en) Apparatus and methods for evaluating the barrier properties of a membrane
US7172859B2 (en) System and method for optimizing tissue barrier transfer of compounds
US7449307B2 (en) Raised surface assay plate
DE69821259T2 (de) Simuliertes biologisches auflösungs- und absorptionssystem
AU2016266020A1 (en) Protective effect of dmpc, dmpg, dmpc/dmpg, egpg, lysopg and lysopc against drugs that cause channelopathies
US20050208477A1 (en) Raised surface assay plate
CN101505598A (zh) 用于神经元再生和功能恢复之σ配体
JP2006516047A (ja) マグネットクランプを備えた経皮アッセイ
Farner et al. Validation of an In vitro-in vivo Assay System for Evaluation of Transdermal Delivery of Caffeine
US20080182293A1 (en) Computerized control of high-throughput transdermal experimental processing and digital analysis of comparative samples
Narayan Overview of drug product development
CA3039596C (en) Protective effect of dmpc, dmpg, dmpc/dmpg, lysopg and lysopc against drugs that cause channelopathies
Wagner et al. Human skin and skin equivalents to study dermal penetration and permeation
Brundage Investigation of the brain distribution and pre-systemic metabolism of tacrine and selected metabolites using microdialysis of brain and blood
Nikolaev et al. The effects of substance P after central administration on the activity of the mesolimbic system of the rat brain as studied by microdialysis
Dick et al. 6 Microneedles for Drug Delivery
Castella et al. Development of an in vitro rat intestine segmental perfusion model to investigate permeability and predict oral fraction absorbed
Chan et al. Assessing the potential bioequivalence requirement for oral immediate release dosage form: Post approval changes for cardiovascular drugs
Kalyanpur Design and Characterization of Ritodrine Hydrochloride Transdermal Delivery by Passive Diffusion and Iontophoresis
Copley et al. OPTIMISING IN VITRO TESTING FOR TRANSDERMAL AND TOPICAL DRUG PRODUCTS
Singla Effects of pathological conditions on the percutaneous absorption of model drugs