EP1556501A1 - Transdermaler assay mit magnetischerklemme - Google Patents

Transdermaler assay mit magnetischerklemme

Info

Publication number
EP1556501A1
EP1556501A1 EP03777948A EP03777948A EP1556501A1 EP 1556501 A1 EP1556501 A1 EP 1556501A1 EP 03777948 A EP03777948 A EP 03777948A EP 03777948 A EP03777948 A EP 03777948A EP 1556501 A1 EP1556501 A1 EP 1556501A1
Authority
EP
European Patent Office
Prior art keywords
sample
transdermal
tissue
transdermal assay
magnetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03777948A
Other languages
English (en)
French (fr)
Other versions
EP1556501A4 (de
Inventor
Michael J. Cima
Hongming Chen
J. Richard Gyory
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transform Pharmaceuticals Inc
Original Assignee
Transform Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/282,505 external-priority patent/US6852526B2/en
Application filed by Transform Pharmaceuticals Inc filed Critical Transform Pharmaceuticals Inc
Publication of EP1556501A1 publication Critical patent/EP1556501A1/de
Publication of EP1556501A4 publication Critical patent/EP1556501A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5088Supracellular entities, e.g. tissue, organisms of vertebrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255Multi-well filtration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/08Investigating permeability, pore-volume, or surface area of porous materials
    • G01N15/0806Details, e.g. sample holders, mounting samples for testing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/025Align devices or objects to ensure defined positions relative to each other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0609Holders integrated in container to position an object
    • B01L2300/0618Holders integrated in container to position an object for removable separation walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
EP03777948A 2002-10-28 2003-10-28 Transdermaler assay mit magnetischerklemme Withdrawn EP1556501A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/282,505 US6852526B2 (en) 2000-07-14 2002-10-28 Transdermal assay with magnetic clamp
US282505 2002-10-28
PCT/US2003/034262 WO2004040006A1 (en) 2002-10-28 2003-10-28 Transdermal assay with magnetic clamp

Publications (2)

Publication Number Publication Date
EP1556501A1 true EP1556501A1 (de) 2005-07-27
EP1556501A4 EP1556501A4 (de) 2009-04-08

Family

ID=34312013

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03777948A Withdrawn EP1556501A4 (de) 2002-10-28 2003-10-28 Transdermaler assay mit magnetischerklemme

Country Status (4)

Country Link
EP (1) EP1556501A4 (de)
JP (1) JP2006516047A (de)
AU (1) AU2003286736A1 (de)
WO (1) WO2004040006A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005057031B4 (de) * 2005-11-25 2011-04-21 Innovent E.V. Technologieentwicklung Vorrichtung für Permeations-oder Stoffdurchgangsuntersuchungen
EP2205967B1 (de) * 2007-10-17 2013-05-01 Syneron Medical Ltd. Überprüfung der auflösungsrate
JP2011133417A (ja) * 2009-12-25 2011-07-07 Lvmc Inc 活性酸素種濃度測定用センサーを用いた皮膚化粧料用抗酸化物質の簡便なスクリーニング方法
JP6418711B2 (ja) * 2014-05-19 2018-12-05 株式会社イントロテック 透過性試験装置
FR3100334B1 (fr) * 2019-09-03 2021-07-30 Fabre Pierre Dermo Cosmetique Dispositif pour la détermination automatisée du passage percutané et de la métabolisation d’une substance

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468321A (en) * 1982-03-12 1984-08-28 Gelman Sciences Inc. Filter device with magnetic filter clamp
US5306467A (en) * 1993-02-17 1994-04-26 Hamilton-Thorn Research Apparatus for measurement of cell concentration in a biological sample employing a magnetic slide loading apparatus
WO2001020341A1 (de) * 1999-09-11 2001-03-22 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Vorrichtung und verfahren zur planarisierung von titerplatten in screening- und/oder synthesesystemen
WO2002006518A1 (en) * 2000-07-14 2002-01-24 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
WO2002016941A2 (en) * 2000-08-23 2002-02-28 The Regents Of The University Of California A combinatorial method for rapid screening of drug delivery formulations
WO2002064247A1 (de) * 2001-02-15 2002-08-22 Merck Patent Gmbh Einrichtung zur verbindung von mikrokomponenten

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3551554A (en) 1968-08-16 1970-12-29 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active agents with dmso
US4317726A (en) * 1981-02-12 1982-03-02 The United States Of America As Represented By The Secretary Of The Army Microbial filter assembly
US4537776A (en) 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4605670A (en) 1984-02-01 1986-08-12 Nitto Electric Industrial Co., Ltd. Method for percutaneously administering metoclopramide
US4863970A (en) 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US5006342A (en) 1986-12-22 1991-04-09 Cygnus Corporation Resilient transdermal drug delivery device
US4820720A (en) 1987-08-24 1989-04-11 Alza Corporation Transdermal drug composition with dual permeation enhancers
US4973468A (en) 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
PT725682E (pt) 1993-10-28 2002-09-30 Houston Advanced Res Ct Dispositivo poroso microfabricado de escoamento
US5490415A (en) * 1994-04-15 1996-02-13 Pharmetrix Corporation Diffusion test apparatus and method
US5695998A (en) * 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US5962250A (en) * 1997-10-28 1999-10-05 Glaxo Group Limited Split multi-well plate and methods

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468321A (en) * 1982-03-12 1984-08-28 Gelman Sciences Inc. Filter device with magnetic filter clamp
US5306467A (en) * 1993-02-17 1994-04-26 Hamilton-Thorn Research Apparatus for measurement of cell concentration in a biological sample employing a magnetic slide loading apparatus
WO2001020341A1 (de) * 1999-09-11 2001-03-22 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Vorrichtung und verfahren zur planarisierung von titerplatten in screening- und/oder synthesesystemen
WO2002006518A1 (en) * 2000-07-14 2002-01-24 Transform Pharmaceuticals, Inc. System and method for optimizing tissue barrier transfer of compounds
WO2002016941A2 (en) * 2000-08-23 2002-02-28 The Regents Of The University Of California A combinatorial method for rapid screening of drug delivery formulations
WO2002064247A1 (de) * 2001-02-15 2002-08-22 Merck Patent Gmbh Einrichtung zur verbindung von mikrokomponenten

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2004040006A1 *

Also Published As

Publication number Publication date
AU2003286736A1 (en) 2004-05-25
JP2006516047A (ja) 2006-06-15
EP1556501A4 (de) 2009-04-08
WO2004040006A1 (en) 2004-05-13

Similar Documents

Publication Publication Date Title
US6852526B2 (en) Transdermal assay with magnetic clamp
US6758099B2 (en) System and method for optimizing tissue barrier transfer of compounds
AU2001277887A1 (en) System and method for optimizing tissue barrier transfer of compounds
US8277762B2 (en) Apparatus and methods for evaluating the barrier properties of a membrane
US7172859B2 (en) System and method for optimizing tissue barrier transfer of compounds
Bohets et al. Strategies for absorption screening in drug discovery and development
US7449307B2 (en) Raised surface assay plate
US10228358B2 (en) Apparatus and method for the assessment of concentration profiling and permeability rates
US20050208477A1 (en) Raised surface assay plate
KR20020071931A (ko) 다양한 고체-형태들의 고도의 자료 처리 편성, 확인 및분석
Jia et al. Recent progress of microfluidic technology for pharmaceutical analysis
CN112041422A (zh) 具有灌注功能的生物反应器
WO2004040006A1 (en) Transdermal assay with magnetic clamp
DK3221696T3 (en) SYSTEM FOR THE CURRENT ASSESSMENT OF PHARMACEUTICAL SOLUTION, ABSORPTION AND PERMEATION AND METHODS OF USE THEREOF
US20080182293A1 (en) Computerized control of high-throughput transdermal experimental processing and digital analysis of comparative samples
Li et al. The evolving role of the Caco-2 cell model to estimate intestinal absorption potential and elucidate transport mechanisms
JPH11299478A (ja) 薬物代謝解析方法およびそのための器具
Paillart et al. Usefulness of functional and structural solution data for the modeling of tRNA-like structures B. Felden, C. Florentz, E. WesthofandR. Giege........................................ 3 Determining the conformation of RNAs in solution. Application to a retroviral system: structure of the HIV-l primer binding site region and effect of tRNA’; IS binding C. Isel, C. Ehresmann, B. Ehresmann and R. Marquet...........................................

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20050427

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

RIN1 Information on inventor provided before grant (corrected)

Inventor name: GONZALEZ-ZUGASTI, JAVIER P.

Inventor name: MONTAGLE, JULIE

Inventor name: LEMMO, ANTHONY, V.

Inventor name: GYORY, J., RICHARD

Inventor name: CHEN, HONGMING

Inventor name: CIMA, MICHAEL, J.

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20090309

17Q First examination report despatched

Effective date: 20090821

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20110503