JP2006514967A5 - - Google Patents
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- Publication number
- JP2006514967A5 JP2006514967A5 JP2004570040A JP2004570040A JP2006514967A5 JP 2006514967 A5 JP2006514967 A5 JP 2006514967A5 JP 2004570040 A JP2004570040 A JP 2004570040A JP 2004570040 A JP2004570040 A JP 2004570040A JP 2006514967 A5 JP2006514967 A5 JP 2006514967A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- breast cancer
- hydroxy tamoxifen
- medium
- breast
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45896303P | 2003-04-01 | 2003-04-01 | |
| US60/458,963 | 2003-04-01 | ||
| PCT/EP2003/015029 WO2004087123A1 (en) | 2003-04-01 | 2003-12-15 | Prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006514967A JP2006514967A (ja) | 2006-05-18 |
| JP2006514967A5 true JP2006514967A5 (enExample) | 2007-02-08 |
| JP5490346B2 JP5490346B2 (ja) | 2014-05-14 |
Family
ID=33131847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004570040A Expired - Lifetime JP5490346B2 (ja) | 2003-04-01 | 2003-12-15 | ４−ヒドロキシタモキシフェンによる乳癌の予防および治療 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7704516B2 (enExample) |
| EP (3) | EP1608353B1 (enExample) |
| JP (1) | JP5490346B2 (enExample) |
| AU (1) | AU2003294973B2 (enExample) |
| CA (1) | CA2519980C (enExample) |
| ES (3) | ES2483896T3 (enExample) |
| IL (1) | IL170807A (enExample) |
| MX (1) | MXPA05010597A (enExample) |
| NO (1) | NO333805B1 (enExample) |
| NZ (1) | NZ542499A (enExample) |
| WO (1) | WO2004087123A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1572178B1 (en) * | 2002-12-18 | 2006-05-03 | Laboratoires Besins International | Treatment of mastalgia with 4-hydroxy tamoxifen |
| EP2050443B1 (en) * | 2002-12-18 | 2017-05-24 | Besins Healthcare Luxembourg SARL | Reduction of breast density with 4-hydroxy tamoxifen |
| CA2519980C (en) * | 2003-04-01 | 2012-04-10 | Laboratoires Besins International | Prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
| DE602004013439T2 (de) * | 2003-06-09 | 2009-06-04 | Ascend Therapeutics, Inc. | Behandlung und prävention von übermässiger narbenbildung mit 4-hydroxy tamoxifen |
| US7968532B2 (en) * | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| EP1579856A1 (en) * | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| AU2005227072B2 (en) * | 2004-03-22 | 2010-08-19 | Besins Healthcare Luxembourg Sarl | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| US20050208139A1 (en) * | 2004-03-22 | 2005-09-22 | Ascend Therapeutics, Inc. | Chemically stable compositions of 4-hydroxy tamoxifen |
| US7507769B2 (en) | 2004-03-22 | 2009-03-24 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| CA2582174C (en) * | 2004-10-14 | 2013-01-29 | Laboratoires Besins International | 4-hydroxy tamoxifen gel formulations |
| EP1647271A1 (en) * | 2004-10-14 | 2006-04-19 | Laboratoires Besins International | 4-Hydroxy tamoxifen gel formulations |
| EP2147674A1 (en) * | 2008-07-24 | 2010-01-27 | Besins Healthcare | Transdermal pharmaceutical compositions comprising danazol |
| US10080760B2 (en) * | 2009-10-27 | 2018-09-25 | Besins Healthcare Luxembourg Sarl | Transdermal pharmaceutical compositions comprising active agents |
| CN110044998B (zh) * | 2014-05-12 | 2021-12-14 | 奎斯特诊断投资公司 | 通过质谱法定量他莫昔芬及其代谢物 |
| KR101571098B1 (ko) | 2014-07-16 | 2015-11-23 | 건국대학교 산학협력단 | 타목시펜 및 메틸설포닐메탄을 유효성분으로 포함하는 암 질환 예방 또는 치료용 약학 조성물 |
| WO2016094854A2 (en) * | 2014-12-12 | 2016-06-16 | Miradx | Methods for treating or preventing cancer in a kras-variant patient and for diagnosing risk of developing multiple primary breast tumors |
| CA3022377A1 (en) | 2016-04-29 | 2017-11-02 | Board Of Regents, The University Of Texas System | Targeted measure of transcriptional activity related to hormone receptors |
| EP3681491A4 (en) | 2017-09-11 | 2021-06-30 | Atossa Therapeutics, Inc. | PROCESS FOR MANUFACTURING AND USE OF ENDOXIFES |
| WO2020023616A1 (en) * | 2018-07-24 | 2020-01-30 | Cornell University | Methods of upregulating tiparp as anticancer strategies |
| WO2021003433A1 (en) | 2019-07-03 | 2021-01-07 | Atossa Therapeutics, Inc. | Sustained release compositions of endoxifen |
| JP2026525970A (ja) * | 2023-07-19 | 2026-08-04 | アトッサ・セラピューティクス・インコーポレイテッド | 抗腫瘍化合物ならびにその使用方法及びその合成方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2558373B1 (fr) * | 1984-01-20 | 1987-07-03 | Mauvais Jarvis Pierre | Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee |
| ATE80152T1 (de) * | 1987-04-21 | 1992-09-15 | Heumann Pharma Gmbh & Co | Stabile loesungsmitteladdukte von z-1-(p-betadimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl) 2-phenylbut-1-en. |
| US5045553A (en) * | 1987-06-24 | 1991-09-03 | Fujisawa Pharmaceutical Company, Ltd. | Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter |
| DE3836862A1 (de) | 1988-10-27 | 1990-05-03 | Schering Ag | Mittel zur transdermalen applikation von steroidhormonen |
| US5189212A (en) * | 1990-09-07 | 1993-02-23 | University Of Georgia Research Foundation, Inc. | Triarylethylene carboxylic acids with estrogenic activity |
| TW218849B (enExample) * | 1991-05-17 | 1994-01-11 | Bristol Myers Squibb Co | |
| US5613958A (en) * | 1993-05-12 | 1997-03-25 | Pp Holdings Inc. | Transdermal delivery systems for the modulated administration of drugs |
| DE4407742C1 (de) * | 1994-03-08 | 1995-06-22 | Hexal Pharma Gmbh | Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat |
| US5720963A (en) * | 1994-08-26 | 1998-02-24 | Mary Kay Inc. | Barrier disruption treatments for structurally deteriorated skin |
| ES2156361T5 (es) * | 1996-03-29 | 2012-12-26 | Keyvest Gmbh | Cosmético o bien composición cosmética para el alisado y la tersura de la piel en el caso de tejido adiposo afectado, en especial en el caso de la "celulitis" |
| AU2513899A (en) | 1997-12-23 | 1999-07-19 | Hexal Ag | Mixture and pharmaceutical composition comprising z-4-hydroxytamoxifen and cyclodextrin |
| US6013270A (en) * | 1998-04-20 | 2000-01-11 | The Procter & Gamble Company | Skin care kit |
| ATE290856T1 (de) | 1999-12-16 | 2005-04-15 | Dermatrends Inc | Hydroxide freisetzende verbindungen zum verbessern der hautdurchlässigkeit |
| DE10033853A1 (de) * | 2000-07-12 | 2002-01-31 | Hexal Ag | Transdermales therapeutisches System mit hochdispersem Siliziumdioxid |
| US20040198706A1 (en) * | 2003-03-11 | 2004-10-07 | Carrara Dario Norberto R. | Methods and formulations for transdermal or transmucosal application of active agents |
| US6503894B1 (en) * | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
| US20030175329A1 (en) * | 2001-10-04 | 2003-09-18 | Cellegy Pharmaceuticals, Inc. | Semisolid topical hormonal compositions and methods for treatment |
| EP1317921B1 (fr) * | 2001-12-07 | 2009-08-19 | Besins International Belgique | Composition pharmaceutique sous forme de gel ou de solution à base de dihydrotestostérone, son procédé de préparation et ses utilisations |
| EP2050443B1 (en) * | 2002-12-18 | 2017-05-24 | Besins Healthcare Luxembourg SARL | Reduction of breast density with 4-hydroxy tamoxifen |
| EP1572178B1 (en) * | 2002-12-18 | 2006-05-03 | Laboratoires Besins International | Treatment of mastalgia with 4-hydroxy tamoxifen |
| CA2519980C (en) * | 2003-04-01 | 2012-04-10 | Laboratoires Besins International | Prevention and treatment of breast cancer with 4-hydroxy tamoxifen |
| DE602004013439T2 (de) * | 2003-06-09 | 2009-06-04 | Ascend Therapeutics, Inc. | Behandlung und prävention von übermässiger narbenbildung mit 4-hydroxy tamoxifen |
| US7968532B2 (en) * | 2003-12-15 | 2011-06-28 | Besins Healthcare Luxembourg | Treatment of gynecomastia with 4-hydroxy tamoxifen |
| US7507769B2 (en) * | 2004-03-22 | 2009-03-24 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| US20050208139A1 (en) | 2004-03-22 | 2005-09-22 | Ascend Therapeutics, Inc. | Chemically stable compositions of 4-hydroxy tamoxifen |
| EP1579856A1 (en) | 2004-03-22 | 2005-09-28 | Laboratoires Besins International | Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen |
| EP1647271A1 (en) * | 2004-10-14 | 2006-04-19 | Laboratoires Besins International | 4-Hydroxy tamoxifen gel formulations |
-
2003
- 2003-12-15 CA CA2519980A patent/CA2519980C/en not_active Expired - Lifetime
- 2003-12-15 MX MXPA05010597A patent/MXPA05010597A/es active IP Right Grant
- 2003-12-15 EP EP03785958.4A patent/EP1608353B1/en not_active Expired - Lifetime
- 2003-12-15 NZ NZ542499A patent/NZ542499A/en not_active IP Right Cessation
- 2003-12-15 EP EP08103007.4A patent/EP1952810B1/en not_active Expired - Lifetime
- 2003-12-15 JP JP2004570040A patent/JP5490346B2/ja not_active Expired - Lifetime
- 2003-12-15 ES ES03785958.4T patent/ES2483896T3/es not_active Expired - Lifetime
- 2003-12-15 US US10/734,638 patent/US7704516B2/en not_active Expired - Lifetime
- 2003-12-15 ES ES08103007.4T patent/ES2456957T3/es not_active Expired - Lifetime
- 2003-12-15 ES ES08103014.0T patent/ES2456958T3/es not_active Expired - Lifetime
- 2003-12-15 EP EP08103014.0A patent/EP1941871B1/en not_active Expired - Lifetime
- 2003-12-15 AU AU2003294973A patent/AU2003294973B2/en not_active Expired
- 2003-12-15 WO PCT/EP2003/015029 patent/WO2004087123A1/en not_active Ceased
-
2005
- 2005-09-12 IL IL170807A patent/IL170807A/en active IP Right Grant
- 2005-09-30 NO NO20054526A patent/NO333805B1/no not_active IP Right Cessation
-
2009
- 2009-01-14 US US12/353,890 patent/US8475814B2/en not_active Expired - Fee Related
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