JP2006514698A5 - - Google Patents

Download PDF

Info

Publication number
JP2006514698A5
JP2006514698A5 JP2005510834A JP2005510834A JP2006514698A5 JP 2006514698 A5 JP2006514698 A5 JP 2006514698A5 JP 2005510834 A JP2005510834 A JP 2005510834A JP 2005510834 A JP2005510834 A JP 2005510834A JP 2006514698 A5 JP2006514698 A5 JP 2006514698A5
Authority
JP
Japan
Prior art keywords
solvent
drug
particles
paclitaxel
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2005510834A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006514698A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/034575 external-priority patent/WO2004098570A1/en
Publication of JP2006514698A publication Critical patent/JP2006514698A/ja
Publication of JP2006514698A5 publication Critical patent/JP2006514698A5/ja
Pending legal-status Critical Current

Links

JP2005510834A 2002-10-30 2003-10-30 ナノ粒子生物活性物質 Pending JP2006514698A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42309302P 2002-10-30 2002-10-30
US49034303P 2003-07-25 2003-07-25
PCT/US2003/034575 WO2004098570A1 (en) 2002-10-30 2003-10-30 Nanoparticulate bioactive agents

Publications (2)

Publication Number Publication Date
JP2006514698A JP2006514698A (ja) 2006-05-11
JP2006514698A5 true JP2006514698A5 (https=) 2006-12-14

Family

ID=33436674

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2005510834A Pending JP2006514698A (ja) 2002-10-30 2003-10-30 ナノ粒子生物活性物質

Country Status (6)

Country Link
US (1) US20040220081A1 (https=)
EP (1) EP1569620A4 (https=)
JP (1) JP2006514698A (https=)
AU (1) AU2003304108B2 (https=)
CA (1) CA2504268A1 (https=)
WO (1) WO2004098570A1 (https=)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143211A (en) * 1995-07-21 2000-11-07 Brown University Foundation Process for preparing microparticles through phase inversion phenomena
US20030096000A1 (en) * 2001-05-31 2003-05-22 Solis Rosa Maria Encapsulation of nanosuspensions in liposomes and microspheres
US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
US20050271737A1 (en) * 2001-06-07 2005-12-08 Chinea Vanessa I Application of a bioactive agent to a substrate
AU2002309172A1 (en) * 2001-06-22 2003-01-08 Pfizer Products Inc. Pharmaceutical compositions containing polymer and drug assemblies
GB0311081D0 (en) 2003-05-14 2003-06-18 Btg Internat Limted Treatment of neurodegenerative conditions
ES2232287B1 (es) * 2003-07-04 2006-11-01 Advanced In Vitro Cell Technologies, S.L. Nanoparticulas de derivados polioxietilenados.
WO2005018632A1 (en) 2003-08-18 2005-03-03 Btg International Limited Treatment of neurodegenerative conditions
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
EP1824458A1 (en) * 2004-11-18 2007-08-29 Bristol-Myers Squibb Company Enteric coated bead comprising epothilone or an epothilone analog, and preparation and administration thereof
MX2007010394A (es) * 2005-02-24 2008-02-19 Elan Pharma Int Ltd Formulaciones nanoparticuladas de docetaxel y analogos del mismo.
JPWO2006093066A1 (ja) * 2005-02-28 2008-08-07 久光製薬株式会社 粘着基材及び該粘着基材を含む医療用貼付製剤
GB0504362D0 (en) 2005-03-02 2005-04-06 Btg Int Ltd Cytokine modulators
CN101272769B (zh) * 2005-07-28 2013-04-24 Isp投资有限公司 生物利用度提高的苯醌类化合物
US8529537B2 (en) * 2005-08-05 2013-09-10 Kimberly-Clark Worldwide, Inc. Absorbent article with enclosures
US20070098802A1 (en) * 2005-10-31 2007-05-03 Isaac Farr Organic nanoparticles and associated methods
WO2008002568A2 (en) * 2006-06-26 2008-01-03 Mutual Pharmaceutical Company, Inc. Active agent formulations, methods of making, and methods of use
GB0613925D0 (en) * 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
US8242165B2 (en) * 2006-10-26 2012-08-14 Creighton University Mucoadhesive nanoparticles for cancer treatment
US8613946B2 (en) 2006-12-21 2013-12-24 Isp Investment Inc. Carotenoids of enhanced bioavailability
JP5508859B2 (ja) 2007-01-26 2014-06-04 アイエスピー インヴェストメンツ インコーポレイテッド 噴霧乾燥製品を製造するための調剤処理方法
US20100290982A1 (en) * 2007-04-13 2010-11-18 University Of North Texas Health Science Center At Fort Worth Solid in oil/water emulsion-diffusion-evaporation formulation for preparing curcumin-loaded plga nanoparticles
BRPI0810899A2 (pt) * 2007-04-13 2014-10-29 Univ North Texas Formulação de nanopartículas de plga ativadas carregadas com agente ativo para substâncias nano-terapêuticas anticâncer direcionais.
WO2008135855A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer
WO2008135828A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
EP2162120B1 (en) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
US9545384B2 (en) 2007-06-04 2017-01-17 Bend Research, Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate
US20090087460A1 (en) * 2007-10-02 2009-04-02 Hamamatsu Photonics K.K. Solid composition, microparticles, microparticle dispersion liquid, and manufacturing methods for these
WO2009052491A2 (en) * 2007-10-18 2009-04-23 Geraghty, Erin Fenoldopam formulations and prodrug derivatives
US9233078B2 (en) 2007-12-06 2016-01-12 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
WO2009073215A1 (en) 2007-12-06 2009-06-11 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US8614057B2 (en) * 2008-06-12 2013-12-24 The Invention Science Fund I, Llc Methods for collecting and detecting oligonucleotides
US8252529B2 (en) * 2008-06-12 2012-08-28 The Invention Science Fund I, Llc Methods for collecting and detecting oligonucleotides
US8252528B2 (en) * 2008-06-12 2012-08-28 The Invention Science Fund I, Llc Methods, compositions, and kits for collecting and detecting oligonucleotides
JP2012501965A (ja) 2008-06-16 2012-01-26 バインド バイオサイエンシズ インコーポレイテッド 薬剤を装填したポリマーナノ粒子及びその製造方法と使用方法
US8613951B2 (en) * 2008-06-16 2013-12-24 Bind Therapeutics, Inc. Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
GB0810990D0 (en) * 2008-06-16 2008-07-23 Q Chip Ltd Device and method of making solid beads
ES2721850T3 (es) 2008-06-16 2019-08-05 Pfizer Nanopartículas poliméricas terapéuticas que comprenden alcaloides vinca y procedimientos de fabricación y uso de las mismas
WO2010068866A2 (en) * 2008-12-12 2010-06-17 Bind Biosciences Therapeutic particles suitable for parenteral administration and methods of making and using same
US20100216804A1 (en) * 2008-12-15 2010-08-26 Zale Stephen E Long Circulating Nanoparticles for Sustained Release of Therapeutic Agents
US20100159010A1 (en) * 2008-12-24 2010-06-24 Mutual Pharmaceutical Company, Inc. Active Agent Formulations, Methods of Making, and Methods of Use
JPWO2010137335A1 (ja) * 2009-05-29 2012-11-12 江崎グリコ株式会社 α−リポ酸ナノ粒子を含有する、ターンオーバー促進用組成物
US8357401B2 (en) 2009-12-11 2013-01-22 Bind Biosciences, Inc. Stable formulations for lyophilizing therapeutic particles
ES2780156T3 (es) 2009-12-15 2020-08-24 Pfizer Composiciones terapéuticas de nanopartículas poliméricas con alta temperatura de transición vítrea o copolímeros de alto peso molecular
EA027666B1 (ru) 2010-05-03 2017-08-31 ТЕИКОКУ ФАРМА ЮСЭй, ИНК. Неводные лекарственные средства в форме проэмульсии на основе таксанов и способы их приготовления и использования
US8652366B2 (en) * 2010-11-01 2014-02-18 Board Of Regents, The University Of Texas System Aerosol-mediated particle synthesis
US9687569B2 (en) 2012-08-16 2017-06-27 University Of Washington Through Its Center For Commercialization Theranostic nanoparticle and methods for making and using the nanoparticle
MX356097B (es) 2012-09-17 2018-05-14 Pfizer Inc Star Proceso para la preparacion de nanoparticulas terapeuticas.
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
US20140187501A1 (en) * 2012-12-28 2014-07-03 Blend Therapeutics, Inc. Targeted Conjugates Encapsulated in Particles and Formulations Thereof
MA39734B1 (fr) 2014-03-14 2019-07-31 Pfizer Nanoparticules thérapeutiques comportant un agent thérapeutique, et leurs procédés de fabrication et d'utilisation
US9874554B1 (en) * 2014-07-16 2018-01-23 Verily Life Sciences Llc Aptamer-based in vivo diagnostic system
EP3302423B1 (en) 2015-06-04 2022-05-25 Crititech, Inc. Particle production system and particle collection device
CA2998483C (en) * 2015-09-16 2022-09-06 Dfb Soria, Llc Delivery of drug nanoparticles and methods of use thereof
KR20180112060A (ko) 2016-02-23 2018-10-11 타베다 세라퓨틱스, 인코포레이티드 Hsp90 표적화된 접합체 및 이의 입자 및 제형
WO2017212345A2 (en) * 2016-03-30 2017-12-14 Synovo Gmbh Detecting microbial infection in wounds
BR112018069628A2 (pt) 2016-04-04 2019-02-12 Crititech, Inc. métodos para tratamento de tumor sólido
WO2018170196A1 (en) 2017-03-15 2018-09-20 Dfb Soria, Llc Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes
EP3615145B1 (en) 2017-06-09 2024-05-15 Crititech, Inc. Compositions for use in the treatment of epithelial cysts by intracystic injection of antineoplastic particles
WO2018231908A1 (en) 2017-06-14 2018-12-20 Crititech, Inc. Methods for treating lung disorders
KR20250057947A (ko) 2017-10-03 2025-04-29 크리티테크, 인크. 암의 치료를 위한 면역치료제의 전신 전달과 조합된 항신생물성 입자의 국소 전달
US11389545B2 (en) * 2018-01-09 2022-07-19 Aqua Regenerative Therapies Llc Bioactive nanoparticles and methods for making same
CN111615389A (zh) 2018-02-01 2020-09-01 科尔沃斯制药股份有限公司 药物调配物
US11497726B2 (en) 2018-03-16 2022-11-15 Dfb Soria, Ll. Topical therapy for the treatment of cervical intraepithelial neoplasia (CIN) and cervical cancer using nanoparticles of taxanes
CN111249476B (zh) * 2020-02-19 2023-09-26 深圳厚存纳米药业有限公司 泊洛沙姆和/或泊洛沙胺与脂质组合中性复合物纳米粒
CN114983976B (zh) * 2022-06-23 2023-07-25 浙江工业大学 一种紫杉醇纳米制剂及其制备方法和应用
WO2024011218A1 (en) * 2022-07-08 2024-01-11 Brown University Polymeric nanoparticles for long acting delivery of a peptide and methods of making and using thereof
WO2024226846A2 (en) 2023-04-26 2024-10-31 Vivtex Corporation Formulation of therapeutic agents for improved permeation

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4757128A (en) * 1986-08-01 1988-07-12 Massachusetts Institute Of Technology High molecular weight polyanhydride and preparation thereof
US5985354A (en) * 1995-06-07 1999-11-16 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
US4861627A (en) * 1987-05-01 1989-08-29 Massachusetts Institute Of Technology Preparation of multiwall polymeric microcapsules
US5000886A (en) * 1987-05-26 1991-03-19 American Cyanamid Company Silicone-hardened pharmaceutical microcapsules and process of making the same
US4997904A (en) * 1989-08-25 1991-03-05 Nova Pharmaceutical Corporation Aromatic polyanhydride compositions
US5271961A (en) * 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
US5175235A (en) * 1990-06-04 1992-12-29 Nova Pharmaceutical Corporation Branched polyanhydrides
US6235313B1 (en) * 1992-04-24 2001-05-22 Brown University Research Foundation Bioadhesive microspheres and their use as drug delivery and imaging systems
US6197346B1 (en) * 1992-04-24 2001-03-06 Brown Universtiy Research Foundation Bioadhesive microspheres and their use as drug delivery and imaging systems
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
EP0804249A2 (en) * 1994-03-15 1997-11-05 Brown University Research Foundation Polymeric gene delivery system
US6143211A (en) * 1995-07-21 2000-11-07 Brown University Foundation Process for preparing microparticles through phase inversion phenomena
EP0840623B1 (en) * 1995-07-21 2007-07-18 Brown University Research Foundation Compositions for gene therapy comprising nucleic acid loaded polymeric microparticles
US5968972A (en) * 1995-10-26 1999-10-19 Baker Norton Pharmaceuticals, Inc. Method for increasing the oral bioactivity of pharmaceutical agents
US6245805B1 (en) * 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
US5955096A (en) * 1996-06-25 1999-09-21 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients
PL335891A1 (en) * 1997-03-27 2000-05-22 Baker Norton Pharma Methods of and compositions for treating ovarian carcinoma
IL149360A0 (en) * 1999-10-27 2002-11-10 Baker Norton Pharma Method and compositions for administering taxanes orally to human patients
FR2806005B1 (fr) * 2000-03-10 2002-06-14 Univ Claude Bernard Lyon Procede de preparation de particules colloidales sous forme de nanocapsules
AU2001270310A1 (en) * 2000-07-07 2002-01-21 Guilford Pharmaceuticals Inc. Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same

Similar Documents

Publication Publication Date Title
AU2003304108B2 (en) Nanoparticulate bioactive agents
JP2006514698A5 (https=)
Bala et al. PLGA nanoparticles in drug delivery: the state of the art
G. Nava-Arzaluz et al. Single emulsion-solvent evaporation technique and modifications for the preparation of pharmaceutical polymeric nanoparticles
Stevanovic et al. Poly (lactide-co-glycolide)-based micro and nanoparticles for the controlled drug delivery of vitamins
Govender et al. PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug
JP3293862B2 (ja) 薬物学的活性物質の調節的放出のために適した粒状医薬組成物及び上記組成物の製法
Reis et al. Preparation of drug-loaded polymeric nanoparticles
Tiruwa A review on nanoparticles-preparation and evaluation parameters
CN112972388B (zh) 卡利拉嗪释放制剂
WO2010102065A1 (en) Pharmaceutical compositions of dextran polymer derivatives
CN104136012A (zh) 制备装载有活性物质的纳米颗粒的方法
Mu et al. Study on surfactant coating of polymeric nanoparticles for controlled delivery of anticancer drug
CN102357077B (zh) 一种包裹难溶性药物的蛋白纳米颗粒及其制备方法
Gadad et al. Nanoparticles and their therapeutic applications in pharmacy
WO2004022100A1 (en) Soild nano pharmaceutical formulation and preparation method thereof
Mehrotra et al. Preparation and characterization and biodistribution studies of lomustine loaded PLGA nanoparticles by interfacial deposition method
Thanos et al. Improving relative bioavailability of dicumarol by reducing particle size and adding the adhesive poly (fumaric-co-sebacic) anhydride
Rong et al. Applications of polymeric nanocapsules in field of drug delivery systems
Sharma et al. Advancements in micellar formulation: drug delivery vehicle for water-insoluble drugs
Gupta et al. Recent advances in the surfactant and controlled release polymer-based solid dispersion
Thanos et al. Enhancing the oral bioavailability of the poorly soluble drug dicumarol with a bioadhesive polymer
Pujitha et al. Engineered Nanocrystals for Poorly Soluble Drug Delivery: A Review.
Sulaiman Khil et al. Several applications of solid lipid nanoparticles in drug delivery
Maruthi et al. Nanoparticles–a review