AU2003304108B2 - Nanoparticulate bioactive agents - Google Patents
Nanoparticulate bioactive agents Download PDFInfo
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- AU2003304108B2 AU2003304108B2 AU2003304108A AU2003304108A AU2003304108B2 AU 2003304108 B2 AU2003304108 B2 AU 2003304108B2 AU 2003304108 A AU2003304108 A AU 2003304108A AU 2003304108 A AU2003304108 A AU 2003304108A AU 2003304108 B2 AU2003304108 B2 AU 2003304108B2
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Classifications
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A—HUMAN NECESSITIES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
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| US42309302P | 2002-10-30 | 2002-10-30 | |
| US60/423,093 | 2002-10-30 | ||
| US49034303P | 2003-07-25 | 2003-07-25 | |
| US60/490,343 | 2003-07-25 | ||
| PCT/US2003/034575 WO2004098570A1 (en) | 2002-10-30 | 2003-10-30 | Nanoparticulate bioactive agents |
Publications (2)
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| AU2003304108A1 AU2003304108A1 (en) | 2004-11-26 |
| AU2003304108B2 true AU2003304108B2 (en) | 2007-03-22 |
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| EP (1) | EP1569620A4 (https=) |
| JP (1) | JP2006514698A (https=) |
| AU (1) | AU2003304108B2 (https=) |
| CA (1) | CA2504268A1 (https=) |
| WO (1) | WO2004098570A1 (https=) |
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| CN111615389A (zh) | 2018-02-01 | 2020-09-01 | 科尔沃斯制药股份有限公司 | 药物调配物 |
| US11497726B2 (en) | 2018-03-16 | 2022-11-15 | Dfb Soria, Ll. | Topical therapy for the treatment of cervical intraepithelial neoplasia (CIN) and cervical cancer using nanoparticles of taxanes |
| CN111249476B (zh) * | 2020-02-19 | 2023-09-26 | 深圳厚存纳米药业有限公司 | 泊洛沙姆和/或泊洛沙胺与脂质组合中性复合物纳米粒 |
| CN114983976B (zh) * | 2022-06-23 | 2023-07-25 | 浙江工业大学 | 一种紫杉醇纳米制剂及其制备方法和应用 |
| WO2024011218A1 (en) * | 2022-07-08 | 2024-01-11 | Brown University | Polymeric nanoparticles for long acting delivery of a peptide and methods of making and using thereof |
| WO2024226846A2 (en) | 2023-04-26 | 2024-10-31 | Vivtex Corporation | Formulation of therapeutic agents for improved permeation |
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| US4757128A (en) * | 1986-08-01 | 1988-07-12 | Massachusetts Institute Of Technology | High molecular weight polyanhydride and preparation thereof |
| US5985354A (en) * | 1995-06-07 | 1999-11-16 | Brown University Research Foundation | Preparation of multiwall polymeric microcapsules from hydrophilic polymers |
| US4861627A (en) * | 1987-05-01 | 1989-08-29 | Massachusetts Institute Of Technology | Preparation of multiwall polymeric microcapsules |
| US5000886A (en) * | 1987-05-26 | 1991-03-19 | American Cyanamid Company | Silicone-hardened pharmaceutical microcapsules and process of making the same |
| US4997904A (en) * | 1989-08-25 | 1991-03-05 | Nova Pharmaceutical Corporation | Aromatic polyanhydride compositions |
| US5271961A (en) * | 1989-11-06 | 1993-12-21 | Alkermes Controlled Therapeutics, Inc. | Method for producing protein microspheres |
| US5175235A (en) * | 1990-06-04 | 1992-12-29 | Nova Pharmaceutical Corporation | Branched polyanhydrides |
| US6235313B1 (en) * | 1992-04-24 | 2001-05-22 | Brown University Research Foundation | Bioadhesive microspheres and their use as drug delivery and imaging systems |
| US6197346B1 (en) * | 1992-04-24 | 2001-03-06 | Brown Universtiy Research Foundation | Bioadhesive microspheres and their use as drug delivery and imaging systems |
| US5916596A (en) * | 1993-02-22 | 1999-06-29 | Vivorx Pharmaceuticals, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
| EP0804249A2 (en) * | 1994-03-15 | 1997-11-05 | Brown University Research Foundation | Polymeric gene delivery system |
| US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
| EP0840623B1 (en) * | 1995-07-21 | 2007-07-18 | Brown University Research Foundation | Compositions for gene therapy comprising nucleic acid loaded polymeric microparticles |
| US5968972A (en) * | 1995-10-26 | 1999-10-19 | Baker Norton Pharmaceuticals, Inc. | Method for increasing the oral bioactivity of pharmaceutical agents |
| US6245805B1 (en) * | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| US5955096A (en) * | 1996-06-25 | 1999-09-21 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients |
| PL335891A1 (en) * | 1997-03-27 | 2000-05-22 | Baker Norton Pharma | Methods of and compositions for treating ovarian carcinoma |
| IL149360A0 (en) * | 1999-10-27 | 2002-11-10 | Baker Norton Pharma | Method and compositions for administering taxanes orally to human patients |
| FR2806005B1 (fr) * | 2000-03-10 | 2002-06-14 | Univ Claude Bernard Lyon | Procede de preparation de particules colloidales sous forme de nanocapsules |
| AU2001270310A1 (en) * | 2000-07-07 | 2002-01-21 | Guilford Pharmaceuticals Inc. | Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same |
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- 2003-10-30 EP EP03816481A patent/EP1569620A4/en not_active Withdrawn
- 2003-10-30 WO PCT/US2003/034575 patent/WO2004098570A1/en not_active Ceased
- 2003-10-30 AU AU2003304108A patent/AU2003304108B2/en not_active Ceased
- 2003-10-30 CA CA002504268A patent/CA2504268A1/en not_active Abandoned
- 2003-10-30 JP JP2005510834A patent/JP2006514698A/ja active Pending
- 2003-10-30 US US10/696,829 patent/US20040220081A1/en not_active Abandoned
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| ISR of WO 2004/098570 * |
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| JP2006514698A (ja) | 2006-05-11 |
| WO2004098570B1 (en) | 2005-03-03 |
| US20040220081A1 (en) | 2004-11-04 |
| EP1569620A4 (en) | 2006-03-22 |
| WO2004098570A1 (en) | 2004-11-18 |
| CA2504268A1 (en) | 2004-11-18 |
| EP1569620A1 (en) | 2005-09-07 |
| AU2003304108A1 (en) | 2004-11-26 |
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