JP2006514698A - ナノ粒子生物活性物質 - Google Patents

ナノ粒子生物活性物質 Download PDF

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Publication number
JP2006514698A
JP2006514698A JP2005510834A JP2005510834A JP2006514698A JP 2006514698 A JP2006514698 A JP 2006514698A JP 2005510834 A JP2005510834 A JP 2005510834A JP 2005510834 A JP2005510834 A JP 2005510834A JP 2006514698 A JP2006514698 A JP 2006514698A
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solvent
formulation
nanoparticles
drug
polymer
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Japanese (ja)
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JP2006514698A5 (enExample
Inventor
マーク アール. クレイツ,
ヤン エス. ジョン,
エディス マトヴィッツ,
デービット ジェー. エンスコアー,
マイケル ジェー. バッセット,
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スフェリックス, インコーポレイテッド
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Publication of JP2006514698A publication Critical patent/JP2006514698A/ja
Publication of JP2006514698A5 publication Critical patent/JP2006514698A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5138Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2005510834A 2002-10-30 2003-10-30 ナノ粒子生物活性物質 Pending JP2006514698A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42309302P 2002-10-30 2002-10-30
US49034303P 2003-07-25 2003-07-25
PCT/US2003/034575 WO2004098570A1 (en) 2002-10-30 2003-10-30 Nanoparticulate bioactive agents

Publications (2)

Publication Number Publication Date
JP2006514698A true JP2006514698A (ja) 2006-05-11
JP2006514698A5 JP2006514698A5 (enExample) 2006-12-14

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Family Applications (1)

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JP2005510834A Pending JP2006514698A (ja) 2002-10-30 2003-10-30 ナノ粒子生物活性物質

Country Status (6)

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US (1) US20040220081A1 (enExample)
EP (1) EP1569620A4 (enExample)
JP (1) JP2006514698A (enExample)
AU (1) AU2003304108B2 (enExample)
CA (1) CA2504268A1 (enExample)
WO (1) WO2004098570A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009542793A (ja) * 2006-07-13 2009-12-03 ユニリーバー・ピーエルシー 製薬組成物の調製
JPWO2010137335A1 (ja) * 2009-05-29 2012-11-12 江崎グリコ株式会社 α−リポ酸ナノ粒子を含有する、ターンオーバー促進用組成物
JP2019513238A (ja) * 2016-03-30 2019-05-23 クオリザイム・ダイアグノスティクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コムパニー・コマンディットゲゼルシャフトQualizyme Diagnostics Gmbh And Co. Kg 創傷における微生物感染の検出

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JP2010524859A (ja) * 2007-04-13 2010-07-22 ユニバーシティー オブ ノース テキサス ヘルス サイエンス センター アット フォートワース 標的型癌ナノ治療に用いる、活性剤が負荷された活性化plgaナノ粒子製剤
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JPH02504025A (ja) * 1987-05-01 1990-11-22 マサチューセッツ インスティテュート オブ テクノロジー 多壁ポリマーマイクロカプセルの調整
JPH11510142A (ja) * 1995-07-21 1999-09-07 ブラウン・ユニバーシティ・リサーチ・ファンデーション 核酸負荷ポリマー微粒子を使用した遺伝子治療法
JP2001501931A (ja) * 1996-10-01 2001-02-13 ビーボウアールエックス ファーマスーティカルズ,インコーポレイテッド 蛋白質安定化した薬理学的活性薬剤、その製造方法およびその使用方法
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009542793A (ja) * 2006-07-13 2009-12-03 ユニリーバー・ピーエルシー 製薬組成物の調製
JP2009542761A (ja) * 2006-07-13 2009-12-03 ユニリーバー・ナームローゼ・ベンノートシヤープ 抗寄生虫組成物に関連する改良
JPWO2010137335A1 (ja) * 2009-05-29 2012-11-12 江崎グリコ株式会社 α−リポ酸ナノ粒子を含有する、ターンオーバー促進用組成物
JP2019513238A (ja) * 2016-03-30 2019-05-23 クオリザイム・ダイアグノスティクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コムパニー・コマンディットゲゼルシャフトQualizyme Diagnostics Gmbh And Co. Kg 創傷における微生物感染の検出

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WO2004098570A1 (en) 2004-11-18
EP1569620A1 (en) 2005-09-07
AU2003304108A1 (en) 2004-11-26
US20040220081A1 (en) 2004-11-04
CA2504268A1 (en) 2004-11-18
WO2004098570B1 (en) 2005-03-03
AU2003304108B2 (en) 2007-03-22
EP1569620A4 (en) 2006-03-22

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