JP2006514611A - 免疫疾患の治療のためのＬｃｋインヒビターの使用 - Google Patents
免疫疾患の治療のためのＬｃｋインヒビターの使用 Download PDFInfo
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- JP2006514611A JP2006514611A JP2004530121A JP2004530121A JP2006514611A JP 2006514611 A JP2006514611 A JP 2006514611A JP 2004530121 A JP2004530121 A JP 2004530121A JP 2004530121 A JP2004530121 A JP 2004530121A JP 2006514611 A JP2006514611 A JP 2006514611A
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- Prior art keywords
- phenyl
- indolinone
- methylene
- phenylamino
- disease
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| PCT/EP2003/008890 WO2004017948A2 (en) | 2002-08-16 | 2003-08-11 | Use of lck inhibitor for treatment of immunologic diseases |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010513424A (ja) * | 2006-12-19 | 2010-04-30 | ガルデルマ・リサーチ・アンド・デヴェロップメント | 炎症性免疫アレルギー成分を含みうる角化障害に関連した皮膚病変の治療のためのネパフェナクまたはその誘導体の使用 |
| JP2011522008A (ja) * | 2008-06-06 | 2011-07-28 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬組み合わせ |
| JP2015071620A (ja) * | 2008-07-18 | 2015-04-16 | エー１エム ファーマ エービーＡ１Ｍ Ｐｈａｒｍａ ＡＢ | ラジカルスカベンジャー及び抗酸化剤アルファ−１−ミクログロブリンの医薬的使用 |
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|---|---|---|---|---|
| PE20060777A1 (es) * | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
| US20060154939A1 (en) * | 2004-12-24 | 2006-07-13 | Boehringer Ingelheim International Gmbh | Medicaments for the Treatment or Prevention of Fibrotic Diseases |
| WO2007057399A2 (en) * | 2005-11-15 | 2007-05-24 | Boehringer Ingelheim International Gmbh | Treatment of cancer with indole derivatives |
| WO2007057397A1 (en) * | 2005-11-15 | 2007-05-24 | Boehringer Ingelheim International Gmbh | Treatment of cancer |
| MX2009008408A (es) | 2007-02-12 | 2009-11-02 | Stefan Hansson | Diagnosis y tratamiento de preeclampsia. |
| US8802384B2 (en) | 2009-03-12 | 2014-08-12 | Boehringer Ingelheim International Gmbh | Method or system using biomarkers for the monitoring of a treatment |
| JP2012526766A (ja) | 2009-05-14 | 2012-11-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 腫瘍性及び線維性疾患の処置における新規な併用療法 |
| US20120107304A1 (en) | 2010-04-27 | 2012-05-03 | Boehringer Ingelheim International Gmbh | Combination therapy in treatment of oncological and fibrotic diseases |
| US20140350022A1 (en) | 2013-05-10 | 2014-11-27 | Boehringer Ingelheim International Gmbh | Efficacious treatment of NSCLC and predictive clinical marker of the responsiveness of a tumour to a treatment |
| AU2014296032A1 (en) * | 2013-07-31 | 2016-03-17 | Windward Pharma, Inc. | Aerosol tyrosine kinase inhibitor compounds and uses thereof |
| EP2837626A1 (en) * | 2013-08-16 | 2015-02-18 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Indolinone derivatives as GRK5 modulators |
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| JP2019522638A (ja) | 2016-05-27 | 2019-08-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ニンテダニブ及びピルフェニドンによる治療開始を判定するためのｅｃｍバイオマーカーの使用 |
| WO2017207643A1 (en) | 2016-06-01 | 2017-12-07 | Boehringer Ingelheim International Gmbh | Use of ecm biomarkers for the determining the treatment onset with nintedanib and pirfenidone |
| JP2020512364A (ja) | 2017-03-28 | 2020-04-23 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 筋ジストロフィーの処置方法において使用するためのニンテダニブ |
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| JPH0892248A (ja) * | 1994-09-26 | 1996-04-09 | Yamanouchi Pharmaceut Co Ltd | インドリノン誘導体 |
| GB9608435D0 (en) * | 1996-04-24 | 1996-06-26 | Celltech Therapeutics Ltd | Chemical compounds |
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| DE19924401A1 (de) | 1999-05-27 | 2000-11-30 | Boehringer Ingelheim Pharma | Neue substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel |
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| UA75054C2 (uk) * | 1999-10-13 | 2006-03-15 | Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг | Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу |
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| AU1047601A (en) * | 1999-11-30 | 2001-06-12 | Pfizer Products Inc. | 2,4-diaminopyrimidine compounds useful as immunosuppressants |
| AR035851A1 (es) * | 2000-03-28 | 2004-07-21 | Wyeth Corp | 3-cianoquinolinas, 3-ciano-1,6-naftiridinas y 3-ciano-1,7-naftiridinas como inhibidoras de proteina quinasas |
| DE10054019A1 (de) | 2000-11-01 | 2002-05-23 | Boehringer Ingelheim Pharma | Neue substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel |
-
2002
- 2002-08-16 DE DE10237423A patent/DE10237423A1/de not_active Withdrawn
-
2003
- 2003-08-11 WO PCT/EP2003/008890 patent/WO2004017948A2/en not_active Ceased
- 2003-08-11 EP EP03792292.9A patent/EP1530466B1/en not_active Expired - Lifetime
- 2003-08-11 PT PT37922929T patent/PT1530466E/pt unknown
- 2003-08-11 DK DK03792292T patent/DK1530466T3/da active
- 2003-08-11 ES ES03792292T patent/ES2530392T3/es not_active Expired - Lifetime
- 2003-08-11 SI SI200332413T patent/SI1530466T1/sl unknown
- 2003-08-11 AU AU2003255413A patent/AU2003255413A1/en not_active Abandoned
- 2003-08-11 EP EP10184940A patent/EP2281561A3/en not_active Withdrawn
- 2003-08-11 CA CA2495350A patent/CA2495350C/en not_active Expired - Lifetime
- 2003-08-11 JP JP2004530121A patent/JP2006514611A/ja active Pending
-
2015
- 2015-03-09 CY CY20151100238T patent/CY1116093T1/el unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010513424A (ja) * | 2006-12-19 | 2010-04-30 | ガルデルマ・リサーチ・アンド・デヴェロップメント | 炎症性免疫アレルギー成分を含みうる角化障害に関連した皮膚病変の治療のためのネパフェナクまたはその誘導体の使用 |
| JP2011522008A (ja) * | 2008-06-06 | 2011-07-28 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬組み合わせ |
| JP2015007143A (ja) * | 2008-06-06 | 2015-01-15 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 医薬組み合わせ |
| JP2015071620A (ja) * | 2008-07-18 | 2015-04-16 | エー１エム ファーマ エービーＡ１Ｍ Ｐｈａｒｍａ ＡＢ | ラジカルスカベンジャー及び抗酸化剤アルファ−１−ミクログロブリンの医薬的使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| DK1530466T3 (da) | 2015-03-16 |
| AU2003255413A8 (en) | 2004-03-11 |
| EP1530466B1 (en) | 2014-12-10 |
| CY1116093T1 (el) | 2017-02-08 |
| WO2004017948A8 (en) | 2005-03-24 |
| EP2281561A3 (en) | 2012-05-09 |
| WO2004017948A2 (en) | 2004-03-04 |
| CA2495350A1 (en) | 2004-03-04 |
| DE10237423A1 (de) | 2004-02-19 |
| EP2281561A2 (en) | 2011-02-09 |
| EP1530466A2 (en) | 2005-05-18 |
| SI1530466T1 (sl) | 2015-03-31 |
| PT1530466E (pt) | 2015-02-24 |
| WO2004017948A3 (en) | 2004-04-22 |
| ES2530392T3 (es) | 2015-03-02 |
| CA2495350C (en) | 2012-05-29 |
| AU2003255413A1 (en) | 2004-03-11 |
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