JP2006514546A5 - - Google Patents

Download PDF

Info

Publication number
JP2006514546A5
JP2006514546A5 JP2004553781A JP2004553781A JP2006514546A5 JP 2006514546 A5 JP2006514546 A5 JP 2006514546A5 JP 2004553781 A JP2004553781 A JP 2004553781A JP 2004553781 A JP2004553781 A JP 2004553781A JP 2006514546 A5 JP2006514546 A5 JP 2006514546A5
Authority
JP
Japan
Prior art keywords
oligonucleotide
seq
composition
organism
complementary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004553781A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006514546A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/036614 external-priority patent/WO2004046327A2/en
Publication of JP2006514546A publication Critical patent/JP2006514546A/ja
Publication of JP2006514546A5 publication Critical patent/JP2006514546A5/ja
Pending legal-status Critical Current

Links

JP2004553781A 2002-11-14 2003-11-14 Bcl−2を標的とする抑制性オリゴヌクレオチド Pending JP2006514546A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42626902P 2002-11-14 2002-11-14
PCT/US2003/036614 WO2004046327A2 (en) 2002-11-14 2003-11-14 Inhibitory oliogonucleotides targeted to bcl-2

Publications (2)

Publication Number Publication Date
JP2006514546A JP2006514546A (ja) 2006-05-11
JP2006514546A5 true JP2006514546A5 (enExample) 2006-12-28

Family

ID=32326325

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004553781A Pending JP2006514546A (ja) 2002-11-14 2003-11-14 Bcl−2を標的とする抑制性オリゴヌクレオチド

Country Status (6)

Country Link
US (2) US7256284B2 (enExample)
EP (1) EP1572970A4 (enExample)
JP (1) JP2006514546A (enExample)
AU (1) AU2003295561A1 (enExample)
CA (1) CA2505680A1 (enExample)
WO (1) WO2004046327A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8815599B2 (en) 2004-06-01 2014-08-26 Pronai Therapeutics, Inc. Methods and compositions for the inhibition of gene expression
US20050287667A1 (en) * 2004-06-01 2005-12-29 Pronai Therapeutics, Inc. Methods and compositions for the inhibition of gene expression
JP5122474B2 (ja) 2005-12-01 2013-01-16 プロネイ・セラピューティクス・インコーポレイテッド 両性リポソーム製剤
WO2009071681A2 (en) * 2007-12-07 2009-06-11 Santaris Pharma A/S Rna antagonist compounds for the modulation of bcl-2
EP2350296A4 (en) * 2008-11-17 2013-04-03 Enzon Pharmaceuticals Inc BRANCHED CATIONIC LIPIDS FOR THE SYSTEM FOR INTRODUCING NUCLEIC ACIDS

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5734033A (en) * 1988-12-22 1998-03-31 The Trustees Of The University Of Pennsylvania Antisense oligonucleotides inhibiting human bcl-2 gene expression
US5831066A (en) * 1988-12-22 1998-11-03 The Trustees Of The University Of Pennsylvania Regulation of bcl-2 gene expression
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US5912147A (en) * 1996-10-22 1999-06-15 Health Research, Inc. Rapid means of quantitating genomic instability
US6041181A (en) * 1997-07-23 2000-03-21 International Business Machines Corporation Method of, system for, and computer program product for providing quick fusion in WHERE constructs
US7704962B1 (en) 1997-10-03 2010-04-27 Board Of Regents, The University Of Texas System Small oligonucleotides with anti-tumor activity
DE69938128D1 (de) * 1998-03-28 2008-03-27 Univ Utah Res Found Zielgerichtete antisense-bibliotheken
KR20020013519A (ko) * 1999-04-08 2002-02-20 추후제출 보편적 및/또는 축퇴성 염기를 포함하는 안티센스올리고뉴클레오티드
US6310047B1 (en) * 1999-08-24 2001-10-30 Virginia Commonwealth University High affinity DNA binding compounds as adjuvants in antisense technology
US7056653B2 (en) * 2000-02-10 2006-06-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Detection of binding of charged species using PH- or potential-sensitive probes
US7795232B1 (en) 2000-08-25 2010-09-14 Genta Incorporated Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers
US7060690B2 (en) * 2001-01-22 2006-06-13 Genta Incorporated Methods and compositions for treating a cell-proliferative disorder using CRE decoy oligomers, BCL-2 antisense oligomers, and hybrid oligomers thereof

Similar Documents

Publication Publication Date Title
EP3472362B1 (en) Papd5 and papd7 inhibitors for treating an hepatitis b infection
JP2002272489A5 (enExample)
RU2005133711A (ru) Антисмысловые олигонуклеотиды (odn) к smad7 и их применение в области медицины
RU2006126643A (ru) Олигомерные соединения для модуляции bcl-2
CA2526893A1 (en) Inhibition of the expression of huntingtin gene
WO1994024144A3 (en) Enhanced triple-helix and double-helix formation with oligomers containing modified purines
EP1224280A2 (en) Design of high affinity rnase h recruiting oligonucleotide
JP2004511201A5 (enExample)
JP2021500016A5 (enExample)
WO1994012633A1 (en) Stable oligonucleotides
BR112020020220A2 (pt) Uso de inibidores da fubp1 para o tratamento de infecção pelo vírus da hepatite b
Bailly et al. The influence of the 2‐amino group of guanine on DNA conformation. Uranyl and DNase I probing of inosine/diaminopurine substituted DNA.
WO2003042385A2 (en) Gene silencing using sense dna and antisense rna hybrid constructs
JP2022534086A5 (enExample)
RU2008125041A (ru) миРНК ПРОТИВ МИОЗИНА VA И ДЕПИГМЕНТАЦИЯ КОЖИ
JP2026074094A (ja) Fubp1発現を調節するための増強されたオリゴヌクレオチド
EP2071030A2 (en) Oligoribonucleotide or peptide nucleic acid which inhibits action of hepatitis C virus
JPH11514220A (ja) キメラオリゴヌクレオチド及びアンチセンス結合部位の確認におけるそれらの使用
KR101783444B1 (ko) miR-33-5p 를 이용한 뇌신경세포 보호 물질 스크리닝 방법
JP2007104971A (ja) ミオスタチンのスプライシング制御アンチセンスオリゴヌクレオチド
JP2008503569A5 (enExample)
IL159759A (en) History of oligoribonucleotide for deliberate inhibition of gene expression, medicinal preparations containing them, methods for their preparation and use
WO2004046327A3 (en) Inhibitory oliogonucleotides targeted to bcl-2
EP1073731B1 (en) Nucleic acid enzyme for rna cleavage
JP2018513841A5 (enExample)