JP2006512324A5 - - Google Patents
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- Publication number
- JP2006512324A5 JP2006512324A5 JP2004553507A JP2004553507A JP2006512324A5 JP 2006512324 A5 JP2006512324 A5 JP 2006512324A5 JP 2004553507 A JP2004553507 A JP 2004553507A JP 2004553507 A JP2004553507 A JP 2004553507A JP 2006512324 A5 JP2006512324 A5 JP 2006512324A5
- Authority
- JP
- Japan
- Prior art keywords
- core
- pharmaceutically acceptable
- coating
- particle
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000011248 coating agent Substances 0.000 claims 34
- 238000000576 coating method Methods 0.000 claims 34
- 239000002245 particle Substances 0.000 claims 34
- 150000003839 salts Chemical class 0.000 claims 27
- 229920000642 polymer Polymers 0.000 claims 25
- HUNXMJYCHXQEGX-UHFFFAOYSA-N zaleplon Chemical compound CCN(C(C)=O)C1=CC=CC(C=2N3N=CC(=C3N=CC=2)C#N)=C1 HUNXMJYCHXQEGX-UHFFFAOYSA-N 0.000 claims 25
- 229960004010 zaleplon Drugs 0.000 claims 25
- 239000008194 pharmaceutical composition Substances 0.000 claims 24
- 230000000147 hypnotic effect Effects 0.000 claims 12
- ZZHLYYDVIOPZBE-UHFFFAOYSA-N Trimeprazine Chemical compound C1=CC=C2N(CC(CN(C)C)C)C3=CC=CC=C3SC2=C1 ZZHLYYDVIOPZBE-UHFFFAOYSA-N 0.000 claims 8
- 239000003814 drug Substances 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 6
- 208000019116 sleep disease Diseases 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- GBBSUAFBMRNDJC-MRXNPFEDSA-N (5R)-zopiclone Chemical compound C1CN(C)CCN1C(=O)O[C@@H]1C2=NC=CN=C2C(=O)N1C1=CC=C(Cl)C=N1 GBBSUAFBMRNDJC-MRXNPFEDSA-N 0.000 claims 4
- UMSGKTJDUHERQW-UHFFFAOYSA-N Brotizolam Chemical compound C1=2C=C(Br)SC=2N2C(C)=NN=C2CN=C1C1=CC=CC=C1Cl UMSGKTJDUHERQW-UHFFFAOYSA-N 0.000 claims 4
- SEQDDYPDSLOBDC-UHFFFAOYSA-N Temazepam Chemical compound N=1C(O)C(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 SEQDDYPDSLOBDC-UHFFFAOYSA-N 0.000 claims 4
- 229960003790 alimemazine Drugs 0.000 claims 4
- 229960003051 brotizolam Drugs 0.000 claims 4
- 239000003326 hypnotic agent Substances 0.000 claims 4
- 208000020685 sleep-wake disease Diseases 0.000 claims 4
- 229960003188 temazepam Drugs 0.000 claims 4
- JOFWLTCLBGQGBO-UHFFFAOYSA-N triazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1Cl JOFWLTCLBGQGBO-UHFFFAOYSA-N 0.000 claims 4
- 229960003386 triazolam Drugs 0.000 claims 4
- ZAFYATHCZYHLPB-UHFFFAOYSA-N zolpidem Chemical compound N1=C2C=CC(C)=CN2C(CC(=O)N(C)C)=C1C1=CC=C(C)C=C1 ZAFYATHCZYHLPB-UHFFFAOYSA-N 0.000 claims 4
- 229960001475 zolpidem Drugs 0.000 claims 4
- 229960000820 zopiclone Drugs 0.000 claims 4
- 230000001154 acute effect Effects 0.000 claims 2
- 230000001684 chronic effect Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 206010019133 Hangover Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42636902P | 2002-11-15 | 2002-11-15 | |
| US10/704,633 US20050038042A1 (en) | 2002-11-15 | 2003-11-12 | Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders |
| PCT/US2003/035046 WO2004045589A1 (en) | 2002-11-15 | 2003-11-14 | Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006512324A JP2006512324A (ja) | 2006-04-13 |
| JP2006512324A5 true JP2006512324A5 (enExample) | 2006-12-28 |
Family
ID=32329106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004553507A Pending JP2006512324A (ja) | 2002-11-15 | 2003-11-14 | 睡眠障害の治療のための短時間作用性催眠薬を含む放出修飾組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050038042A1 (enExample) |
| EP (1) | EP1562560A1 (enExample) |
| JP (1) | JP2006512324A (enExample) |
| AU (1) | AU2003291715A1 (enExample) |
| RU (1) | RU2005119303A (enExample) |
| WO (1) | WO2004045589A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL163548A0 (en) * | 2002-02-15 | 2005-12-18 | Biogal Pharmaceutical Co Ltd | Powder composition comprising zaleplon of defined particle size distribution and pharmaceutical products made therefrom |
| EP2343073A3 (en) * | 2003-12-11 | 2011-10-12 | Sepracor Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| US20050215521A1 (en) * | 2003-12-22 | 2005-09-29 | Karim Lalji | Modafinil combination therapy for improving sleep quality |
| EP1696959A2 (en) * | 2003-12-24 | 2006-09-06 | Sepracor, Inc. | Melatonin combination therapy for improving sleep quality |
| US7658945B2 (en) | 2004-02-17 | 2010-02-09 | Transcept Pharmaceuticals, Inc. | Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof |
| EP1742624B1 (en) * | 2004-02-18 | 2010-01-06 | Sepracor, Inc. | Dopamine-agonist combination therapy with sedatives for improving sleep quality |
| GB0423800D0 (en) | 2004-10-27 | 2004-12-01 | Orexo Ab | New pharmaceutical formulations |
| GB0423964D0 (en) * | 2004-10-28 | 2004-12-01 | Jagotec Ag | Dosage form |
| US20070287740A1 (en) * | 2005-05-25 | 2007-12-13 | Transcept Pharmaceuticals, Inc. | Compositions and methods of treating middle-of-the night insomnia |
| US20070225322A1 (en) * | 2005-05-25 | 2007-09-27 | Transoral Pharmaceuticals, Inc. | Compositions and methods for treating middle-of-the night insomnia |
| US20060276501A1 (en) * | 2005-05-25 | 2006-12-07 | Transoral Pharmaceuticals, Inc. | Solid compositions for treating middle-of-the-night insomnia |
| US20070020333A1 (en) * | 2005-07-20 | 2007-01-25 | Chin-Chih Chiang | Controlled release of hypnotic agents |
| TWI274889B (en) * | 2005-10-06 | 2007-03-01 | Elan Microelectronics Corp | Resistive touch screen measurement system |
| AR056633A1 (es) * | 2005-12-07 | 2007-10-17 | Gador Sa | Composiciones farmaceuticas de agentes hipnoticos de accion corta en forma de liberacion modificada y los procedimientos para preparar dichas formulaciones |
| US8309104B2 (en) * | 2006-03-02 | 2012-11-13 | Watson Pharmaceuticals, Inc. | Oral controlled release formulation for sedative and hypnotic agents |
| KR20070091960A (ko) * | 2006-03-08 | 2007-09-12 | 주식회사종근당 | 졸피뎀 또는 그의 염을 포함하는 안전한 제어방출형 제제조성물 |
| WO2007107878A2 (en) * | 2006-03-17 | 2007-09-27 | Aurobindo Pharma Limited | Solid dosage forms of hypnotic agent |
| US20070243252A1 (en) * | 2006-04-17 | 2007-10-18 | Actavis Group Ptc Hf | Oral Dosage Formulations and Methods of Preparing the Same |
| US20070243245A1 (en) * | 2006-04-17 | 2007-10-18 | Actavis Group Ptc Hf | Oral Dosage Formulations, Methods of Preparing the Same, and Methods of Reducing Food Effects on Drug Release |
| HUE029173T2 (hu) * | 2006-04-26 | 2017-02-28 | Alphapharm Pty Ltd | Szabályozott hatóanyag-leadású készítmények, amelyek tartalmaznak nem bevont diszkrét egység(ek)et és egy késleltetett hatóanyag-leadású mátrixot |
| EP1970056A1 (en) * | 2007-03-15 | 2008-09-17 | Polichem S.A. | Time-specific delayed/pulsatile release dosage forms |
| WO2009006299A2 (en) * | 2007-06-29 | 2009-01-08 | Dr. Reddy's Laboratories Ltd. | Multi-particulate systems |
| WO2010064139A2 (en) * | 2008-12-04 | 2010-06-10 | Intec Pharma Ltd. | Zaleplon gastroretentive drug delivery system |
| RU2384336C1 (ru) * | 2009-04-22 | 2010-03-20 | Маргарита Алексеевна Морозова | Фармацевтический состав для коррекции психосоматических проявлений |
| CA2934595C (en) * | 2014-02-06 | 2022-06-21 | Sequential Medicine Limited | Composition and method for aiding sleep |
| WO2019071270A1 (en) * | 2017-10-06 | 2019-04-11 | Adare Pharmaceuticals, Inc. | PHARMACEUTICAL COMPOSITIONS |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4728512A (en) * | 1985-05-06 | 1988-03-01 | American Home Products Corporation | Formulations providing three distinct releases |
| BR9802915A (pt) * | 1997-09-12 | 2000-01-11 | Oscar Gold | Procedimento para formar composições farmaceuticas em pilulas ou granulos substancialmente esfericos, de ação controlada e continuada, contendo como agente ativo o (7-bromo-1,3-diidro-5-(2-piridninilo)-2h-1,4-benzodiazep ina-2(1h)-um) |
| CA2348871C (en) * | 1998-11-02 | 2009-04-14 | John G. Devane | Multiparticulate modified release composition |
| EP1005863A1 (en) * | 1998-12-04 | 2000-06-07 | Synthelabo | Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof |
| WO2000059479A1 (en) * | 1999-04-06 | 2000-10-12 | Pharmaquest Ltd. | Pharmaceutical dosage form for pulsatile delivery of methylphenidate |
| US6485746B1 (en) * | 2000-08-25 | 2002-11-26 | Neurocrine Biosciences, Inc. | Controlled-release sedative-hypnotic compositions and methods related thereto |
| ATE241968T1 (de) * | 1999-08-26 | 2003-06-15 | Neurocrine Biosciences Inc | Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren |
-
2003
- 2003-11-12 US US10/704,633 patent/US20050038042A1/en not_active Abandoned
- 2003-11-14 JP JP2004553507A patent/JP2006512324A/ja active Pending
- 2003-11-14 EP EP03768607A patent/EP1562560A1/en not_active Withdrawn
- 2003-11-14 AU AU2003291715A patent/AU2003291715A1/en not_active Abandoned
- 2003-11-14 WO PCT/US2003/035046 patent/WO2004045589A1/en not_active Ceased
- 2003-11-14 RU RU2005119303/15A patent/RU2005119303A/ru not_active Application Discontinuation
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