AU2003291715A1 - Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders - Google Patents
Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders Download PDFInfo
- Publication number
- AU2003291715A1 AU2003291715A1 AU2003291715A AU2003291715A AU2003291715A1 AU 2003291715 A1 AU2003291715 A1 AU 2003291715A1 AU 2003291715 A AU2003291715 A AU 2003291715A AU 2003291715 A AU2003291715 A AU 2003291715A AU 2003291715 A1 AU2003291715 A1 AU 2003291715A1
- Authority
- AU
- Australia
- Prior art keywords
- core
- pharmaceutically acceptable
- zaleplon
- coating
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 230000000147 hypnotic effect Effects 0.000 title claims description 60
- 208000019116 sleep disease Diseases 0.000 title claims description 22
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- 230000001939 inductive effect Effects 0.000 claims description 9
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Classifications
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- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
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- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
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- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
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- Veterinary Medicine (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42636902P | 2002-11-15 | 2002-11-15 | |
| US60/426,369 | 2002-11-15 | ||
| US10/704,633 | 2003-11-12 | ||
| US10/704,633 US20050038042A1 (en) | 2002-11-15 | 2003-11-12 | Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders |
| PCT/US2003/035046 WO2004045589A1 (en) | 2002-11-15 | 2003-11-14 | Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003291715A1 true AU2003291715A1 (en) | 2004-06-15 |
Family
ID=32329106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003291715A Abandoned AU2003291715A1 (en) | 2002-11-15 | 2003-11-14 | Modified release composition comprising a short-acting hypnotic for treatment of sleep disorders |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050038042A1 (enExample) |
| EP (1) | EP1562560A1 (enExample) |
| JP (1) | JP2006512324A (enExample) |
| AU (1) | AU2003291715A1 (enExample) |
| RU (1) | RU2005119303A (enExample) |
| WO (1) | WO2004045589A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL163548A0 (en) * | 2002-02-15 | 2005-12-18 | Biogal Pharmaceutical Co Ltd | Powder composition comprising zaleplon of defined particle size distribution and pharmaceutical products made therefrom |
| EP2343073A3 (en) * | 2003-12-11 | 2011-10-12 | Sepracor Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| US20050215521A1 (en) * | 2003-12-22 | 2005-09-29 | Karim Lalji | Modafinil combination therapy for improving sleep quality |
| EP1696959A2 (en) * | 2003-12-24 | 2006-09-06 | Sepracor, Inc. | Melatonin combination therapy for improving sleep quality |
| US7658945B2 (en) | 2004-02-17 | 2010-02-09 | Transcept Pharmaceuticals, Inc. | Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof |
| EP1742624B1 (en) * | 2004-02-18 | 2010-01-06 | Sepracor, Inc. | Dopamine-agonist combination therapy with sedatives for improving sleep quality |
| GB0423800D0 (en) | 2004-10-27 | 2004-12-01 | Orexo Ab | New pharmaceutical formulations |
| GB0423964D0 (en) * | 2004-10-28 | 2004-12-01 | Jagotec Ag | Dosage form |
| US20070287740A1 (en) * | 2005-05-25 | 2007-12-13 | Transcept Pharmaceuticals, Inc. | Compositions and methods of treating middle-of-the night insomnia |
| US20070225322A1 (en) * | 2005-05-25 | 2007-09-27 | Transoral Pharmaceuticals, Inc. | Compositions and methods for treating middle-of-the night insomnia |
| US20060276501A1 (en) * | 2005-05-25 | 2006-12-07 | Transoral Pharmaceuticals, Inc. | Solid compositions for treating middle-of-the-night insomnia |
| US20070020333A1 (en) * | 2005-07-20 | 2007-01-25 | Chin-Chih Chiang | Controlled release of hypnotic agents |
| TWI274889B (en) * | 2005-10-06 | 2007-03-01 | Elan Microelectronics Corp | Resistive touch screen measurement system |
| AR056633A1 (es) * | 2005-12-07 | 2007-10-17 | Gador Sa | Composiciones farmaceuticas de agentes hipnoticos de accion corta en forma de liberacion modificada y los procedimientos para preparar dichas formulaciones |
| US8309104B2 (en) * | 2006-03-02 | 2012-11-13 | Watson Pharmaceuticals, Inc. | Oral controlled release formulation for sedative and hypnotic agents |
| KR20070091960A (ko) * | 2006-03-08 | 2007-09-12 | 주식회사종근당 | 졸피뎀 또는 그의 염을 포함하는 안전한 제어방출형 제제조성물 |
| WO2007107878A2 (en) * | 2006-03-17 | 2007-09-27 | Aurobindo Pharma Limited | Solid dosage forms of hypnotic agent |
| US20070243252A1 (en) * | 2006-04-17 | 2007-10-18 | Actavis Group Ptc Hf | Oral Dosage Formulations and Methods of Preparing the Same |
| US20070243245A1 (en) * | 2006-04-17 | 2007-10-18 | Actavis Group Ptc Hf | Oral Dosage Formulations, Methods of Preparing the Same, and Methods of Reducing Food Effects on Drug Release |
| HUE029173T2 (hu) * | 2006-04-26 | 2017-02-28 | Alphapharm Pty Ltd | Szabályozott hatóanyag-leadású készítmények, amelyek tartalmaznak nem bevont diszkrét egység(ek)et és egy késleltetett hatóanyag-leadású mátrixot |
| EP1970056A1 (en) * | 2007-03-15 | 2008-09-17 | Polichem S.A. | Time-specific delayed/pulsatile release dosage forms |
| WO2009006299A2 (en) * | 2007-06-29 | 2009-01-08 | Dr. Reddy's Laboratories Ltd. | Multi-particulate systems |
| WO2010064139A2 (en) * | 2008-12-04 | 2010-06-10 | Intec Pharma Ltd. | Zaleplon gastroretentive drug delivery system |
| RU2384336C1 (ru) * | 2009-04-22 | 2010-03-20 | Маргарита Алексеевна Морозова | Фармацевтический состав для коррекции психосоматических проявлений |
| CA2934595C (en) * | 2014-02-06 | 2022-06-21 | Sequential Medicine Limited | Composition and method for aiding sleep |
| WO2019071270A1 (en) * | 2017-10-06 | 2019-04-11 | Adare Pharmaceuticals, Inc. | PHARMACEUTICAL COMPOSITIONS |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4728512A (en) * | 1985-05-06 | 1988-03-01 | American Home Products Corporation | Formulations providing three distinct releases |
| BR9802915A (pt) * | 1997-09-12 | 2000-01-11 | Oscar Gold | Procedimento para formar composições farmaceuticas em pilulas ou granulos substancialmente esfericos, de ação controlada e continuada, contendo como agente ativo o (7-bromo-1,3-diidro-5-(2-piridninilo)-2h-1,4-benzodiazep ina-2(1h)-um) |
| CA2348871C (en) * | 1998-11-02 | 2009-04-14 | John G. Devane | Multiparticulate modified release composition |
| EP1005863A1 (en) * | 1998-12-04 | 2000-06-07 | Synthelabo | Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof |
| WO2000059479A1 (en) * | 1999-04-06 | 2000-10-12 | Pharmaquest Ltd. | Pharmaceutical dosage form for pulsatile delivery of methylphenidate |
| US6485746B1 (en) * | 2000-08-25 | 2002-11-26 | Neurocrine Biosciences, Inc. | Controlled-release sedative-hypnotic compositions and methods related thereto |
| ATE241968T1 (de) * | 1999-08-26 | 2003-06-15 | Neurocrine Biosciences Inc | Sedativ hypnotische zusammensetzungen mit gesteuerter freisetzung und diesbezügliche verfahren |
-
2003
- 2003-11-12 US US10/704,633 patent/US20050038042A1/en not_active Abandoned
- 2003-11-14 JP JP2004553507A patent/JP2006512324A/ja active Pending
- 2003-11-14 EP EP03768607A patent/EP1562560A1/en not_active Withdrawn
- 2003-11-14 AU AU2003291715A patent/AU2003291715A1/en not_active Abandoned
- 2003-11-14 WO PCT/US2003/035046 patent/WO2004045589A1/en not_active Ceased
- 2003-11-14 RU RU2005119303/15A patent/RU2005119303A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006512324A (ja) | 2006-04-13 |
| RU2005119303A (ru) | 2006-01-27 |
| US20050038042A1 (en) | 2005-02-17 |
| EP1562560A1 (en) | 2005-08-17 |
| WO2004045589A1 (en) | 2004-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |