JP2006511536A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006511536A5 JP2006511536A5 JP2004560372A JP2004560372A JP2006511536A5 JP 2006511536 A5 JP2006511536 A5 JP 2006511536A5 JP 2004560372 A JP2004560372 A JP 2004560372A JP 2004560372 A JP2004560372 A JP 2004560372A JP 2006511536 A5 JP2006511536 A5 JP 2006511536A5
- Authority
- JP
- Japan
- Prior art keywords
- weight
- drug
- water
- group
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/317,657 US20040115226A1 (en) | 2002-12-12 | 2002-12-12 | Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same |
| PCT/US2003/038979 WO2004054540A2 (en) | 2002-12-12 | 2003-12-09 | Solid compositions with improved bio-availability of insoluble or poorly water soluble drugs and a corresponding process for preparing such |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006511536A JP2006511536A (ja) | 2006-04-06 |
| JP2006511536A5 true JP2006511536A5 (enExample) | 2006-09-21 |
Family
ID=32506185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004560372A Pending JP2006511536A (ja) | 2002-12-12 | 2003-12-09 | 水貧溶性薬物のバイオアベイラビリティーを改善する自由流動性固形製剤およびその製造方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US20040115226A1 (enExample) |
| JP (1) | JP2006511536A (enExample) |
| AU (1) | AU2003300833A1 (enExample) |
| WO (1) | WO2004054540A2 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005016312A1 (en) | 2003-08-13 | 2005-02-24 | Nobex Corporation | Micro-particle fatty acid salt solid dosage formulations for therapeutic agents |
| CA2536283A1 (en) * | 2003-08-20 | 2005-03-03 | Ajinomoto Co., Inc. | Pharmaceutical preparations having an improved solubility |
| US20050220825A1 (en) * | 2004-03-10 | 2005-10-06 | Adrian Funke | Molecular dispersions of drospirenone |
| WO2005105040A2 (en) * | 2004-04-26 | 2005-11-10 | Micelle Products, Inc. | Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications |
| JP2007191396A (ja) * | 2005-01-07 | 2007-08-02 | Rohto Pharmaceut Co Ltd | 皮膚外用剤 |
| GB0612809D0 (en) * | 2006-06-28 | 2006-08-09 | Univ Sunderland | Formulation |
| US20100061969A1 (en) * | 2006-11-22 | 2010-03-11 | Asahi Kasei Pharma Corporation | Dietary supplement, anti-fatigue agent or physical endurance enhancer, functional food, or cosmetic |
| WO2009070978A1 (fr) * | 2007-11-22 | 2009-06-11 | Yu He | Libération rapide dans la cavité buccale des produits de santé et procédé de préparation associé |
| EP2111854A1 (en) | 2008-04-22 | 2009-10-28 | Lek Pharmaceuticals D.D. | Self-microemulsifying systems incorporated into liquid core microcapsules |
| EP2400840A4 (en) * | 2009-02-24 | 2012-08-01 | Madeira Therapeutics | LIQUID STATINE FORMULATIONS |
| ES2363964B1 (es) | 2009-11-20 | 2012-08-22 | Gp Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados. |
| ES2363965B1 (es) | 2009-11-20 | 2013-01-24 | Gp Pharm S.A. | Cápsulas de principios activos betabloqueantes y ésteres de ácidos grasos poliinsaturados. |
| US20110160168A1 (en) | 2009-12-31 | 2011-06-30 | Differential Drug Development Associates, Llc | Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols |
| CN103228266B (zh) | 2010-10-29 | 2017-11-14 | 健康科学西部大学 | 三元混合物制剂 |
| US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
| US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
| AR086400A1 (es) | 2011-05-13 | 2013-12-11 | Trimel Pharmaceuticals Corp | Formulaciones en gel intranasal de testosterona en dosis de menor potencia y uso de las mismas para el tratamiento de la anorgasmia o el trastorno de deseo sexual hipoactivo |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| EA201791738A1 (ru) | 2012-05-09 | 2018-03-30 | Вестерн Юниверсити Оф Хелт Сайенсиз | Пролипосомальные композиции тестостерона |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
| ES2907284T3 (es) | 2013-03-15 | 2022-04-22 | Marius Pharmaceuticals Llc | Formulaciones de emulsión |
| US20140370084A1 (en) * | 2013-06-18 | 2014-12-18 | Therapeuticsmd, Inc. | Estradiol formulations and therapies |
| JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． | 天然の併用ホルモン補充療法剤及び療法 |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| CA3127502A1 (en) * | 2019-02-12 | 2020-08-20 | Sumitomo Dainippon Pharma Oncology, Inc. | Formulations comprising heterocyclic protein kinase inhibitors |
| US12403146B2 (en) | 2019-10-30 | 2025-09-02 | Marius Pharmaceuticals, Inc. | Preferred oral testosterone undecanoate therapy to achieve testosterone replacement treatment |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59148718A (ja) * | 1983-02-10 | 1984-08-25 | Fujisawa Pharmaceut Co Ltd | ユビデカレノン組成物 |
| US4572915A (en) * | 1984-05-01 | 1986-02-25 | Bioglan Laboratories | Clear micellized solutions of fat soluble essential nutrients |
| US4874795A (en) * | 1985-04-02 | 1989-10-17 | Yesair David W | Composition for delivery of orally administered drugs and other substances |
| US4900734A (en) * | 1987-08-27 | 1990-02-13 | Maxson Wayne S | Novel pharmaceutical composition containing estradiol and progesterone for oral administration |
| DE69229779T2 (de) * | 1991-04-19 | 1999-12-23 | Lds Technologies, Inc. | Konvertierbare mikroemulsionsverbindungen |
| US6054136A (en) * | 1993-09-30 | 2000-04-25 | Gattefosse S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
| US6312704B1 (en) * | 1993-09-30 | 2001-11-06 | Gattefosse, S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
| FR2714621B1 (fr) * | 1994-01-06 | 1996-02-23 | Centre Nat Rech Scient | Procédé de préparation de liposomes sans utilisation de solvant organique. |
| US5938990A (en) * | 1994-07-01 | 1999-08-17 | Roche Vitamins Inc. | Encapsulation of oleophilic substances and compositions produced thereby |
| US5863919A (en) * | 1994-07-25 | 1999-01-26 | University Of South Florida | Lock and key micelles and monomer building blocks therefor |
| US5908635A (en) * | 1994-08-05 | 1999-06-01 | The United States Of America As Represented By The Department Of Health And Human Services | Method for the liposomal delivery of nucleic acids |
| US6120794A (en) * | 1995-09-26 | 2000-09-19 | University Of Pittsburgh | Emulsion and micellar formulations for the delivery of biologically active substances to cells |
| IL117773A (en) * | 1996-04-02 | 2000-10-31 | Pharmos Ltd | Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability |
| US5993858A (en) * | 1996-06-14 | 1999-11-30 | Port Systems L.L.C. | Method and formulation for increasing the bioavailability of poorly water-soluble drugs |
| US5827533A (en) * | 1997-02-06 | 1998-10-27 | Duke University | Liposomes containing active agents aggregated with lipid surfactants |
| IT1289939B1 (it) * | 1997-02-20 | 1998-10-19 | Angelini Ricerche Spa | Composizione farmaceutica acquosa comprendente un principio attivo altamente insolubile in acqua |
| US6322810B1 (en) * | 1997-07-14 | 2001-11-27 | Hayat Alkan-Onyuksel | Materials and methods for making improved micelle compositions |
| IT1294205B1 (it) * | 1997-07-23 | 1999-03-24 | Farmigea Spa | Procedimento per la solubilizzazione in acqua e in veicoli acquosi di sostanze farmacologicamente attive |
| US6027747A (en) * | 1997-11-11 | 2000-02-22 | Terracol; Didier | Process for the production of dry pharmaceutical forms and the thus obtained pharmaceutical compositions |
| AR018528A1 (es) * | 1997-12-12 | 2001-11-28 | Expression Genetics Inc | Mezcla polimerica biodegradable de micelas para transferencia genetica |
| US6013665A (en) * | 1997-12-16 | 2000-01-11 | Abbott Laboratories | Method for enhancing the absorption and transport of lipid soluble compounds using structured glycerides |
| US6017545A (en) * | 1998-02-10 | 2000-01-25 | Modi; Pankaj | Mixed micellar delivery system and method of preparation |
| FR2782006B1 (fr) * | 1998-08-07 | 2002-04-19 | Gattefosse Ets Sa | Composition a liberation prolongee apte a former une micro-emulsion |
| EP2127642A3 (en) * | 1998-08-13 | 2010-02-24 | Cima Labs, Inc. | Microemulsions as solid dosage forms for oral administration |
| AU3227000A (en) * | 1999-02-10 | 2000-08-29 | Ontogeny, Inc. | Methods of inducing insulin positive progenitor cells |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| GB9908309D0 (en) * | 1999-04-12 | 1999-06-02 | Phares Pharm Res Nv | Lipid aggregate forming compositions and their use |
| US6248360B1 (en) * | 2000-06-21 | 2001-06-19 | International Health Management Associates, Inc. | Complexes to improve oral absorption of poorly absorbable antibiotics |
| US6890961B2 (en) * | 2002-02-01 | 2005-05-10 | Micelle Products, Inc. | Clear micellized formulations of β-carotene and method of treating leukoplakia |
-
2002
- 2002-12-12 US US10/317,657 patent/US20040115226A1/en not_active Abandoned
-
2003
- 2003-12-09 AU AU2003300833A patent/AU2003300833A1/en not_active Abandoned
- 2003-12-09 JP JP2004560372A patent/JP2006511536A/ja active Pending
- 2003-12-09 WO PCT/US2003/038979 patent/WO2004054540A2/en not_active Ceased
-
2006
- 2006-07-27 US US11/494,131 patent/US20060263397A1/en not_active Abandoned
- 2006-07-27 US US11/494,129 patent/US20070009559A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006511536A5 (enExample) | ||
| EP1980242B1 (en) | Liquid compositions as a micro-emulsion pre-concentrate comprising drospirenone moleculary dispersed | |
| JP2006511536A (ja) | 水貧溶性薬物のバイオアベイラビリティーを改善する自由流動性固形製剤およびその製造方法 | |
| JP4943975B2 (ja) | 高いバイオアベイラビリティーを有するフェノフィブレート医薬組成物及びそれを調製するための方法 | |
| KR101512404B1 (ko) | 디하이드로피리딘 칼슘 채널 길항제를 포함하는 향상된 의약 조성물 및 이의 준비 방법 | |
| SK287869B6 (sk) | Beta-carboline pharmaceutical compositions | |
| JP2004533999A (ja) | 医薬形態のアトルバスタチンカルシウム、その構成物、及びアトルバスタチンカルシウムを含む医薬製剤 | |
| EP2648700A1 (en) | Pharmaceutical composition comprising dutasteride | |
| WO1999030689A1 (en) | Pharmaceutical suspension tablet compositions | |
| JP2008531509A (ja) | 医薬品成分の改良された分散性を有する錠剤 | |
| KR20070119700A (ko) | 페노피브레이트 및 계면 활성제 혼합물을 함유하는 제제 | |
| EP3154522A1 (en) | Agomelatine in solution adsorbates and compositions | |
| KR101617054B1 (ko) | 고형내복제제 | |
| Lee et al. | Effect of poloxamer on the dissolution of felodipine and preparation of controlled release matrix tablets containing felodipine | |
| CN114126590B (zh) | 医药制剂及其制造方法 | |
| EP1952805B1 (en) | Tablet containing hydrogenated phospholipids | |
| EA024365B1 (ru) | Фармацевтическая композиция, содержащая тамсулозин, и способ ее получения | |
| JP2023052494A (ja) | 抗凝固薬の即時放出医薬製剤及びその調製方法 | |
| JP5774308B2 (ja) | 水溶性ビノレルビン塩の安定な医薬組成物 | |
| JP2864737B2 (ja) | 徐放性製剤用基剤並びに徐放性製剤及び該製剤の製造方法 | |
| JP4467678B2 (ja) | テプレノン含有固形製剤 | |
| JP4993274B2 (ja) | フェノフィブラート含有製剤組成物の製造方法 | |
| JP2004518679A (ja) | リポイドビヒクルに分散させたサムパトリラートを含む薬学的組成物 | |
| JP2022069437A (ja) | 医薬製剤およびその製造方法 | |
| JPWO2003072095A1 (ja) | ソファルコン含有組成物 |