JP2006508972A - 一酸化炭素の治療的放出 - Google Patents
一酸化炭素の治療的放出 Download PDFInfo
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- JP2006508972A JP2006508972A JP2004552908A JP2004552908A JP2006508972A JP 2006508972 A JP2006508972 A JP 2006508972A JP 2004552908 A JP2004552908 A JP 2004552908A JP 2004552908 A JP2004552908 A JP 2004552908A JP 2006508972 A JP2006508972 A JP 2006508972A
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- Prior art keywords
- metal carbonyl
- ligand
- stabilizer
- guanylate cyclase
- metal
- Prior art date
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0227135A GB2395431A (en) | 2002-11-20 | 2002-11-20 | Combination of a metal carbonyl compound and a guanylate cyclase stimulant or stabilizer for the therapeutic delivery of carbon monoxide |
| PCT/GB2003/005061 WO2004045599A1 (en) | 2002-11-20 | 2003-11-20 | Therapeutic delivery of carbon monoxide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006508972A true JP2006508972A (ja) | 2006-03-16 |
| JP2006508972A5 JP2006508972A5 (enExample) | 2007-01-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004552908A Pending JP2006508972A (ja) | 2002-11-20 | 2003-11-20 | 一酸化炭素の治療的放出 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060147548A1 (enExample) |
| EP (1) | EP1562579A1 (enExample) |
| JP (1) | JP2006508972A (enExample) |
| AU (1) | AU2003302013A1 (enExample) |
| GB (1) | GB2395431A (enExample) |
| WO (1) | WO2004045599A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007269665A (ja) * | 2006-03-30 | 2007-10-18 | Hidetoshi Tsuchida | 配位子置換型輸液製剤 |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19944226A1 (de) * | 1999-09-15 | 2001-03-29 | Aventis Pharma Gmbh | Verfahren zum Nachweis von oxidierten Formen der löslichen Guanylatzyklase und Verfahren zum Screening nach Aktivatoren der löslichen Guanylatzyklase mit oxidiertem Hämeisen |
| GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
| US20080026984A1 (en) * | 2002-02-04 | 2008-01-31 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| EP1476168A2 (en) | 2002-02-04 | 2004-11-17 | ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. | Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases |
| US7968605B2 (en) | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| GB2395432B (en) | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
| DE102005047946A1 (de) * | 2005-10-06 | 2007-05-03 | Bayer Healthcare Ag | Verwendung von Aktivatoren der löslichen Guanylatzyklase zur Behandlung von akuten und chronischen Lungenkrankheiten |
| WO2007073226A1 (en) * | 2005-12-20 | 2007-06-28 | Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda | Method for treating a mammal by administration of a compound having the ability to release co |
| GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
| WO2010102216A2 (en) | 2009-03-05 | 2010-09-10 | The Uab Research Foundation | Enhancing coagulation or reducing fibrinolysis |
| US8927750B2 (en) | 2011-02-04 | 2015-01-06 | Universitaet Zu Koeln | Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules |
| WO2012145520A2 (en) | 2011-04-19 | 2012-10-26 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
| WO2013013179A1 (en) | 2011-07-21 | 2013-01-24 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
| DE102014008685A1 (de) * | 2014-06-13 | 2015-12-17 | Lorenz Meinel | Freisetzungssystem für therapeutisches Gas |
| CN108752389A (zh) * | 2018-08-22 | 2018-11-06 | 广西师范学院 | 治疗高血压的芳基钌配合物及其制备方法和用途 |
| CN108752391A (zh) * | 2018-08-22 | 2018-11-06 | 广西师范学院 | 治疗胃癌的芳基钌配合物及其制备方法和用途 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10501539A (ja) * | 1994-06-18 | 1998-02-10 | エルティエス ローマン テラピイ−システム ジイエムビイエイチ | 一酸化炭素供給を行う活性物質を含む経皮吸収型製剤 |
| WO2000056743A1 (en) * | 1999-03-19 | 2000-09-28 | Anormed Inc. | Pharmaceutical compositions comprising metal complexes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6523194A (en) * | 1993-03-26 | 1994-10-24 | Biorelease Technologies, Inc. | Compositions including heme-containing proteins and methods relating thereto |
| US7678390B2 (en) * | 1999-04-01 | 2010-03-16 | Yale University | Carbon monoxide as a biomarker and therapeutic agent |
| GB9920566D0 (en) * | 1999-08-31 | 1999-11-03 | Univ London | Screen for axon viability |
| GB0111872D0 (en) * | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
-
2002
- 2002-11-20 GB GB0227135A patent/GB2395431A/en not_active Withdrawn
-
2003
- 2003-11-20 EP EP03811438A patent/EP1562579A1/en not_active Withdrawn
- 2003-11-20 WO PCT/GB2003/005061 patent/WO2004045599A1/en not_active Ceased
- 2003-11-20 US US10/535,226 patent/US20060147548A1/en not_active Abandoned
- 2003-11-20 JP JP2004552908A patent/JP2006508972A/ja active Pending
- 2003-11-20 AU AU2003302013A patent/AU2003302013A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10501539A (ja) * | 1994-06-18 | 1998-02-10 | エルティエス ローマン テラピイ−システム ジイエムビイエイチ | 一酸化炭素供給を行う活性物質を含む経皮吸収型製剤 |
| WO2000056743A1 (en) * | 1999-03-19 | 2000-09-28 | Anormed Inc. | Pharmaceutical compositions comprising metal complexes |
Non-Patent Citations (1)
| Title |
|---|
| JPN6010021483, Ｃａｎ Ｊ Ｐｈａｒｍａｃｏｌ, 2000, ７８，４, ３４３−３４９ * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007269665A (ja) * | 2006-03-30 | 2007-10-18 | Hidetoshi Tsuchida | 配位子置換型輸液製剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2395431A (en) | 2004-05-26 |
| GB0227135D0 (en) | 2002-12-24 |
| AU2003302013A8 (en) | 2004-06-15 |
| WO2004045599A1 (en) | 2004-06-03 |
| US20060147548A1 (en) | 2006-07-06 |
| AU2003302013A1 (en) | 2004-06-15 |
| EP1562579A1 (en) | 2005-08-17 |
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