GB2395431A - Combination of a metal carbonyl compound and a guanylate cyclase stimulant or stabilizer for the therapeutic delivery of carbon monoxide - Google Patents
Combination of a metal carbonyl compound and a guanylate cyclase stimulant or stabilizer for the therapeutic delivery of carbon monoxide Download PDFInfo
- Publication number
- GB2395431A GB2395431A GB0227135A GB0227135A GB2395431A GB 2395431 A GB2395431 A GB 2395431A GB 0227135 A GB0227135 A GB 0227135A GB 0227135 A GB0227135 A GB 0227135A GB 2395431 A GB2395431 A GB 2395431A
- Authority
- GB
- United Kingdom
- Prior art keywords
- metal carbonyl
- metal
- stabilizer
- guanylate cyclase
- stimulant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 title claims description 83
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- Reproductive Health (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0227135A GB2395431A (en) | 2002-11-20 | 2002-11-20 | Combination of a metal carbonyl compound and a guanylate cyclase stimulant or stabilizer for the therapeutic delivery of carbon monoxide |
| JP2004552908A JP2006508972A (ja) | 2002-11-20 | 2003-11-20 | 一酸化炭素の治療的放出 |
| EP03811438A EP1562579A1 (en) | 2002-11-20 | 2003-11-20 | Therapeutic delivery of carbon monoxide |
| US10/535,226 US20060147548A1 (en) | 2002-11-20 | 2003-11-20 | Therapeutic delivery of carbon monoxide |
| PCT/GB2003/005061 WO2004045599A1 (en) | 2002-11-20 | 2003-11-20 | Therapeutic delivery of carbon monoxide |
| AU2003302013A AU2003302013A1 (en) | 2002-11-20 | 2003-11-20 | Therapeutic delivery of carbon monoxide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0227135A GB2395431A (en) | 2002-11-20 | 2002-11-20 | Combination of a metal carbonyl compound and a guanylate cyclase stimulant or stabilizer for the therapeutic delivery of carbon monoxide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB0227135D0 GB0227135D0 (en) | 2002-12-24 |
| GB2395431A true GB2395431A (en) | 2004-05-26 |
Family
ID=9948224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB0227135A Withdrawn GB2395431A (en) | 2002-11-20 | 2002-11-20 | Combination of a metal carbonyl compound and a guanylate cyclase stimulant or stabilizer for the therapeutic delivery of carbon monoxide |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060147548A1 (enExample) |
| EP (1) | EP1562579A1 (enExample) |
| JP (1) | JP2006508972A (enExample) |
| AU (1) | AU2003302013A1 (enExample) |
| GB (1) | GB2395431A (enExample) |
| WO (1) | WO2004045599A1 (enExample) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007039155A3 (de) * | 2005-10-06 | 2007-10-11 | Bayer Healthcare Ag | Verwendung von aktivatoren der löslichen guanylatzyklase zur behandlung von akuten und chronischen lungenkrankheiten |
| US7964220B2 (en) | 2002-02-04 | 2011-06-21 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Method for treating a mammal by administration of a compound having the ability to release CO |
| US7968605B2 (en) | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| US7989650B2 (en) | 2002-11-20 | 2011-08-02 | Hemocorm Limited | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
| US8236339B2 (en) | 2001-05-15 | 2012-08-07 | Hemocorm Limited | Therapeutic delivery of carbon monoxide |
| US8389572B2 (en) | 2006-01-24 | 2013-03-05 | Hemocorm Limited | Therapeutic delivery of carbon monoxide |
| US9062089B2 (en) | 2011-07-21 | 2015-06-23 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
| US9163044B2 (en) | 2011-04-19 | 2015-10-20 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19944226A1 (de) * | 1999-09-15 | 2001-03-29 | Aventis Pharma Gmbh | Verfahren zum Nachweis von oxidierten Formen der löslichen Guanylatzyklase und Verfahren zum Screening nach Aktivatoren der löslichen Guanylatzyklase mit oxidiertem Hämeisen |
| US20080026984A1 (en) * | 2002-02-04 | 2008-01-31 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| US20070207217A1 (en) * | 2003-02-03 | 2007-09-06 | Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda | Method for treating a mammal by administration of a compound having the ability to release CO |
| JP5020525B2 (ja) * | 2006-03-30 | 2012-09-05 | 財団法人生産開発科学研究所 | 配位子置換型輸液製剤 |
| CA2754549A1 (en) | 2009-03-05 | 2010-09-10 | The Uab Research Foundation | Enhancing coagulation or reducing fibrinolysis |
| US8927750B2 (en) | 2011-02-04 | 2015-01-06 | Universitaet Zu Koeln | Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules |
| DE102014008685A1 (de) * | 2014-06-13 | 2015-12-17 | Lorenz Meinel | Freisetzungssystem für therapeutisches Gas |
| CN108752389A (zh) * | 2018-08-22 | 2018-11-06 | 广西师范学院 | 治疗高血压的芳基钌配合物及其制备方法和用途 |
| CN108752391A (zh) * | 2018-08-22 | 2018-11-06 | 广西师范学院 | 治疗胃癌的芳基钌配合物及其制备方法和用途 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002092075A2 (en) * | 2001-05-15 | 2002-11-21 | Northwick Park Institute For Medical Research | Therapeutic delivery of carbon monoxide |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0804244A1 (en) * | 1993-03-26 | 1997-11-05 | Biorelease Technologies, Inc. | Compositions including heme-containing proteins and methods relating thereto |
| DE4421433C1 (de) * | 1994-06-18 | 1995-06-08 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System mit Wirkstoffen, die Kohlenmonoxid-Quellen darstellen, Verfahren zu seiner Herstellung und seine Verwendung |
| IL145290A0 (en) * | 1999-03-19 | 2002-06-30 | Anormed Inc | Pharmaceutical compositions comprising complexes |
| US7678390B2 (en) * | 1999-04-01 | 2010-03-16 | Yale University | Carbon monoxide as a biomarker and therapeutic agent |
| GB9920566D0 (en) * | 1999-08-31 | 1999-11-03 | Univ London | Screen for axon viability |
-
2002
- 2002-11-20 GB GB0227135A patent/GB2395431A/en not_active Withdrawn
-
2003
- 2003-11-20 US US10/535,226 patent/US20060147548A1/en not_active Abandoned
- 2003-11-20 EP EP03811438A patent/EP1562579A1/en not_active Withdrawn
- 2003-11-20 WO PCT/GB2003/005061 patent/WO2004045599A1/en not_active Ceased
- 2003-11-20 AU AU2003302013A patent/AU2003302013A1/en not_active Abandoned
- 2003-11-20 JP JP2004552908A patent/JP2006508972A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002092075A2 (en) * | 2001-05-15 | 2002-11-21 | Northwick Park Institute For Medical Research | Therapeutic delivery of carbon monoxide |
Non-Patent Citations (1)
| Title |
|---|
| MEDLINE Abstract Accession No NLM11916917 & Diabetes, 2002, Vol. 51(4), pages 994-999 * |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8236339B2 (en) | 2001-05-15 | 2012-08-07 | Hemocorm Limited | Therapeutic delivery of carbon monoxide |
| US7964220B2 (en) | 2002-02-04 | 2011-06-21 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Method for treating a mammal by administration of a compound having the ability to release CO |
| US7968605B2 (en) | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| US9023402B2 (en) | 2002-02-04 | 2015-05-05 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Method for treating a mammal by administration of a compound having the ability to release CO |
| US7989650B2 (en) | 2002-11-20 | 2011-08-02 | Hemocorm Limited | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
| WO2007039155A3 (de) * | 2005-10-06 | 2007-10-11 | Bayer Healthcare Ag | Verwendung von aktivatoren der löslichen guanylatzyklase zur behandlung von akuten und chronischen lungenkrankheiten |
| JP2009510142A (ja) * | 2005-10-06 | 2009-03-12 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | 急性および慢性肺障害の処置のための可溶性グアニル酸シクラーゼ活性化剤の使用 |
| US8389572B2 (en) | 2006-01-24 | 2013-03-05 | Hemocorm Limited | Therapeutic delivery of carbon monoxide |
| US9163044B2 (en) | 2011-04-19 | 2015-10-20 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
| US9062089B2 (en) | 2011-07-21 | 2015-06-23 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
| US9611286B2 (en) | 2011-07-21 | 2017-04-04 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0227135D0 (en) | 2002-12-24 |
| US20060147548A1 (en) | 2006-07-06 |
| AU2003302013A8 (en) | 2004-06-15 |
| JP2006508972A (ja) | 2006-03-16 |
| WO2004045599A1 (en) | 2004-06-03 |
| AU2003302013A1 (en) | 2004-06-15 |
| EP1562579A1 (en) | 2005-08-17 |
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Legal Events
| Date | Code | Title | Description |
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| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |