JP2006508192A - 抗細菌薬としてのオキサゾリジノンおよび/またはイソオキサゾリン誘導体 - Google Patents
抗細菌薬としてのオキサゾリジノンおよび/またはイソオキサゾリン誘導体 Download PDFInfo
- Publication number
- JP2006508192A JP2006508192A JP2005510253A JP2005510253A JP2006508192A JP 2006508192 A JP2006508192 A JP 2006508192A JP 2005510253 A JP2005510253 A JP 2005510253A JP 2005510253 A JP2005510253 A JP 2005510253A JP 2006508192 A JP2006508192 A JP 2006508192A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- ring
- group
- alkoxy
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 COCCN1CC*CC1 Chemical compound COCCN1CC*CC1 0.000 description 14
- MZQAFIBEFNZUKF-UHFFFAOYSA-N CC(C)COCc1ncccc1 Chemical compound CC(C)COCc1ncccc1 MZQAFIBEFNZUKF-UHFFFAOYSA-N 0.000 description 2
- NEQLWELJDXTJSL-UHFFFAOYSA-N CCCC(OCC(C1)ON=C1c(cc1)ncc1Br)=O Chemical compound CCCC(OCC(C1)ON=C1c(cc1)ncc1Br)=O NEQLWELJDXTJSL-UHFFFAOYSA-N 0.000 description 2
- YDMQYKHPVWNRQG-LBOXEOMUSA-N CC(C)(C)OC(C(C1)ON=C1c(nc1)ccc1-c(ccc(N(C[C@H](C[n]1nncc1)O1)C1=O)c1)c1F)=O Chemical compound CC(C)(C)OC(C(C1)ON=C1c(nc1)ccc1-c(ccc(N(C[C@H](C[n]1nncc1)O1)C1=O)c1)c1F)=O YDMQYKHPVWNRQG-LBOXEOMUSA-N 0.000 description 1
- JKFAEPSLHQYBFI-PDIWNELESA-N CC(C)(OC1)O[C@H]1[C@H](C1)ON=C1c(nc1)ccc1-c(ccc(N(C[C@H](C[n]1nncc1)O1)C1=O)c1)c1F Chemical compound CC(C)(OC1)O[C@H]1[C@H](C1)ON=C1c(nc1)ccc1-c(ccc(N(C[C@H](C[n]1nncc1)O1)C1=O)c1)c1F JKFAEPSLHQYBFI-PDIWNELESA-N 0.000 description 1
- ZWRQRJDGFIEHSN-UHFFFAOYSA-N CC(C)C(C)OCc1cccnc1 Chemical compound CC(C)C(C)OCc1cccnc1 ZWRQRJDGFIEHSN-UHFFFAOYSA-N 0.000 description 1
- OQVPITWJXXKBBX-UHFFFAOYSA-N CC(C)COC(C)c1cccnc1 Chemical compound CC(C)COC(C)c1cccnc1 OQVPITWJXXKBBX-UHFFFAOYSA-N 0.000 description 1
- PZJGPCRXHKYVHF-UHFFFAOYSA-N CC(C)COCc1ccncc1 Chemical compound CC(C)COCc1ccncc1 PZJGPCRXHKYVHF-UHFFFAOYSA-N 0.000 description 1
- CHKPRWAPACQMMW-FQEVSTJZSA-N CC(NC[C@@H](CN1c(cc2)ccc2-c(cc2)ccc2C2=NOC(CO)(CO)C2)OC1=O)=O Chemical compound CC(NC[C@@H](CN1c(cc2)ccc2-c(cc2)ccc2C2=NOC(CO)(CO)C2)OC1=O)=O CHKPRWAPACQMMW-FQEVSTJZSA-N 0.000 description 1
- TWUKYWKTFHLMFL-SECBINFHSA-N CC(OC[C@@H](CN1c(cc2)cc(F)c2I)OC1=O)=O Chemical compound CC(OC[C@@H](CN1c(cc2)cc(F)c2I)OC1=O)=O TWUKYWKTFHLMFL-SECBINFHSA-N 0.000 description 1
- LHMKOEKAFCWREP-LICLKQGHSA-O CCC(CCCC(CC)N)C(CCCC1)CCC/C=C1/C#[N+]O Chemical compound CCC(CCCC(CC)N)C(CCCC1)CCC/C=C1/C#[N+]O LHMKOEKAFCWREP-LICLKQGHSA-O 0.000 description 1
- NEQLWELJDXTJSL-JTQLQIEISA-N CCCC(OC[C@H](C1)ON=C1c(cc1)ncc1Br)=O Chemical compound CCCC(OC[C@H](C1)ON=C1c(cc1)ncc1Br)=O NEQLWELJDXTJSL-JTQLQIEISA-N 0.000 description 1
- QGYSYQVEMNDFPB-UHFFFAOYSA-N CCOC(CC(C1)ON=C1c(cc1)ncc1Br)OCC Chemical compound CCOC(CC(C1)ON=C1c(cc1)ncc1Br)OCC QGYSYQVEMNDFPB-UHFFFAOYSA-N 0.000 description 1
- NNUKGGJBMPLKIW-UHFFFAOYSA-N CCc1cnc[n]1C Chemical compound CCc1cnc[n]1C NNUKGGJBMPLKIW-UHFFFAOYSA-N 0.000 description 1
- VWIIJDNADIEEDB-UHFFFAOYSA-N CN(CCO1)C1=O Chemical compound CN(CCO1)C1=O VWIIJDNADIEEDB-UHFFFAOYSA-N 0.000 description 1
- RUPOGMLYXRAWMU-UHFFFAOYSA-N CNC(C(C1)ON=C1c(nc1)ccc1-c(ccc(N(CC(C[n]1nncc1)O1)C1=O)c1)c1F)=O Chemical compound CNC(C(C1)ON=C1c(nc1)ccc1-c(ccc(N(CC(C[n]1nncc1)O1)C1=O)c1)c1F)=O RUPOGMLYXRAWMU-UHFFFAOYSA-N 0.000 description 1
- UZGDNAPEIIAPRR-UHFFFAOYSA-N Cc1c[n](CC(CN2c3cc(F)ccc3)OC2=O)nn1 Chemical compound Cc1c[n](CC(CN2c3cc(F)ccc3)OC2=O)nn1 UZGDNAPEIIAPRR-UHFFFAOYSA-N 0.000 description 1
- WXMQYEJTHTYUIA-KRWDZBQOSA-N O=C1O[C@@H](C[n]2nncc2)CN1c(cc1)cc(F)c1-c(cc1)ccc1C1=NOCC1 Chemical compound O=C1O[C@@H](C[n]2nncc2)CN1c(cc1)cc(F)c1-c(cc1)ccc1C1=NOCC1 WXMQYEJTHTYUIA-KRWDZBQOSA-N 0.000 description 1
- QPXDQUKPKMOQMA-UHFFFAOYSA-N OCC(CO)(C1)ON=C1c(cc1F)ccc1Br Chemical compound OCC(CO)(C1)ON=C1c(cc1F)ccc1Br QPXDQUKPKMOQMA-UHFFFAOYSA-N 0.000 description 1
- QZJYVQMAOLEMRM-UHFFFAOYSA-N OCC(CO)(C1)ON=C1c(nc1)ccc1Br Chemical compound OCC(CO)(C1)ON=C1c(nc1)ccc1Br QZJYVQMAOLEMRM-UHFFFAOYSA-N 0.000 description 1
- RBASMEPZOXDPIH-JHVJFLLYSA-N OC[C@@H]([C@H](C1)ON=C1c(nc1)ccc1-c(ccc(N(C[C@H](C[n]1nncc1)O1)C1=O)c1)c1F)O Chemical compound OC[C@@H]([C@H](C1)ON=C1c(nc1)ccc1-c(ccc(N(C[C@H](C[n]1nncc1)O1)C1=O)c1)c1F)O RBASMEPZOXDPIH-JHVJFLLYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0227702A GB0227702D0 (en) | 2002-11-28 | 2002-11-28 | Chemical compounds |
| GB0304725A GB0304725D0 (en) | 2003-03-01 | 2003-03-01 | Chemical compounds |
| GB0318608A GB0318608D0 (en) | 2003-08-08 | 2003-08-08 | Chemical compounds |
| PCT/GB2003/005087 WO2004048392A1 (en) | 2002-11-28 | 2003-11-24 | Oxazolidinone and / or isoxazoline derivatives as antibacterial agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006508192A true JP2006508192A (ja) | 2006-03-09 |
| JP2006508192A5 JP2006508192A5 (enExample) | 2007-01-25 |
Family
ID=32397650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005510253A Pending JP2006508192A (ja) | 2002-11-28 | 2003-11-24 | 抗細菌薬としてのオキサゾリジノンおよび/またはイソオキサゾリン誘導体 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060116400A1 (enExample) |
| EP (1) | EP1567532A1 (enExample) |
| JP (1) | JP2006508192A (enExample) |
| KR (1) | KR20050085193A (enExample) |
| AU (1) | AU2003302404B2 (enExample) |
| BR (1) | BR0316688A (enExample) |
| CA (1) | CA2507468A1 (enExample) |
| HK (1) | HK1079794A1 (enExample) |
| IL (1) | IL168747A0 (enExample) |
| MX (1) | MXPA05005651A (enExample) |
| NO (1) | NO20052534L (enExample) |
| NZ (1) | NZ540147A (enExample) |
| SA (1) | SA04250088A (enExample) |
| TW (1) | TW200533666A (enExample) |
| WO (1) | WO2004048392A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006519247A (ja) * | 2003-03-01 | 2006-08-24 | アストラゼネカ アクチボラグ | 抗生物質として有用なヒドロキシメチル置換ジヒドロイソオキサゾール誘導体 |
| JP2007500708A (ja) * | 2003-07-29 | 2007-01-18 | リブ−エックス ファーマシューティカルズ,インコーポレイテッド | ビアリールオキサゾリジノンの合成方法 |
| JP2015505846A (ja) * | 2011-12-19 | 2015-02-26 | サウディ ベーシック インダストリーズ コーポレイション | メタロセン錯体を調製するプロセス |
| JP2015506916A (ja) * | 2011-12-19 | 2015-03-05 | サウディ ベーシック インダストリーズ コーポレイション | メタロセン錯体を調製するプロセス |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0401005A3 (en) * | 2001-09-11 | 2007-11-28 | Astrazeneca Ab | Oxazolidinone and/or isoxazoline antibacterials, process for their preparation, their use and pharmaceutical compositions containing them |
| AU2003207340A1 (en) | 2002-02-28 | 2003-09-09 | Astrazeneca Ab | 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents |
| AU2003209994A1 (en) | 2002-02-28 | 2003-09-09 | Astrazeneca Ab | Oxazolidinone derivatives, processes for their preparation, and pharmaceutical compositions containing them |
| AR043050A1 (es) | 2002-09-26 | 2005-07-13 | Rib X Pharmaceuticals Inc | Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos |
| GB0227701D0 (en) * | 2002-11-28 | 2003-01-08 | Astrazeneca Ab | Chemical compounds |
| US7498350B2 (en) | 2002-11-28 | 2009-03-03 | Astrazeneca Ab | Oxazolidinones as antibacterial agents |
| SG2009082793A (en) | 2003-06-03 | 2015-03-30 | Rib X Pharmaceuticals Inc | Biaryl heterocyclic compounds and methods of making and using the same |
| US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
| EP1660465B1 (en) * | 2003-07-29 | 2014-12-17 | Melinta Therapeutics, Inc. | Process for the synthesis of biaryl oxazolidinones |
| TW200526649A (en) | 2003-12-17 | 2005-08-16 | Rib X Pharmaceuticals Inc | Halogenated biaryl heterocyclic compounds and methods of making and using the same |
| KR100854211B1 (ko) * | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| US8202843B2 (en) | 2004-02-27 | 2012-06-19 | Rib-X Pharmaceuticals, Inc. | Macrocyclic compounds and methods of making and using the same |
| US20080064689A1 (en) * | 2004-05-25 | 2008-03-13 | Astrazeneca Ab | 3-[4-(6-Pyridin-3-Yl)-3-Phenyl] -5-(1H-1,2,3-Triazol-1-Ylmethyl)-1,3-Oxazolidin-2-Ones as Antibacterial Agents |
| WO2005116024A1 (en) * | 2004-05-25 | 2005-12-08 | Astrazeneca Ab | 3- (4- (2-dihydroisoxazol-3-ylpyridin-5-yl) phenyl) -5-triazol-1-ylmethyloxazolidin-2-one derivaives as mao inhibitors for the treatment of bacterial infections |
| ATE496914T1 (de) | 2005-06-08 | 2011-02-15 | Rib X Pharmaceuticals Inc | Verfahren zur synthese von triazolen |
| WO2010042887A2 (en) | 2008-10-10 | 2010-04-15 | Trius Therapeutics | Methods for preparing oxazolidinones and compositions containing them |
| US8426389B2 (en) | 2009-02-03 | 2013-04-23 | Trius Therapeutics, Inc. | Crystalline form of R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate |
| US8580767B2 (en) * | 2009-05-28 | 2013-11-12 | Trius Therapeutics, Inc. | Oxazolidinone containing dimer compounds, compositions and methods to make and use |
| WO2021000297A1 (en) | 2019-07-03 | 2021-01-07 | Merck Sharp & Dohme Corp. | Compounds and methods of use thereof as antibacterial agents |
| CN113149924B (zh) * | 2021-03-29 | 2023-11-03 | 苏州大学 | 一种异噁唑啉的简单制备方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02124877A (ja) * | 1988-07-29 | 1990-05-14 | E I Du Pont De Nemours & Co | アミノメチルオキソオキサゾリジニルアリールベンゼン誘導体 |
| JP2003535860A (ja) * | 2000-06-05 | 2003-12-02 | ドン・ア・ファーム・カンパニー・リミテッド | 新規なオキサゾリジノン誘導体及びその製造方法 |
| JP2005507386A (ja) * | 2001-09-11 | 2005-03-17 | アストラゼネカ アクチボラグ | 抗菌剤としてのオキサゾリジノン及び/又はイソオキサゾリン |
| JP2006515286A (ja) * | 2002-11-28 | 2006-05-25 | アストラゼネカ アクチボラグ | 抗細菌性化合物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
-
2003
- 2003-11-24 NZ NZ540147A patent/NZ540147A/en unknown
- 2003-11-24 BR BR0316688-0A patent/BR0316688A/pt not_active IP Right Cessation
- 2003-11-24 HK HK05112116.9A patent/HK1079794A1/zh unknown
- 2003-11-24 EP EP03811807A patent/EP1567532A1/en not_active Withdrawn
- 2003-11-24 JP JP2005510253A patent/JP2006508192A/ja active Pending
- 2003-11-24 US US10/536,686 patent/US20060116400A1/en not_active Abandoned
- 2003-11-24 AU AU2003302404A patent/AU2003302404B2/en not_active Ceased
- 2003-11-24 KR KR1020057009644A patent/KR20050085193A/ko not_active Ceased
- 2003-11-24 WO PCT/GB2003/005087 patent/WO2004048392A1/en not_active Ceased
- 2003-11-24 CA CA002507468A patent/CA2507468A1/en not_active Abandoned
- 2003-11-24 MX MXPA05005651A patent/MXPA05005651A/es unknown
-
2004
- 2004-04-01 TW TW093109096A patent/TW200533666A/zh unknown
- 2004-04-25 SA SA04250088A patent/SA04250088A/ar unknown
-
2005
- 2005-05-23 IL IL168747A patent/IL168747A0/en unknown
- 2005-05-26 NO NO20052534A patent/NO20052534L/no not_active Application Discontinuation
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02124877A (ja) * | 1988-07-29 | 1990-05-14 | E I Du Pont De Nemours & Co | アミノメチルオキソオキサゾリジニルアリールベンゼン誘導体 |
| JP2003535860A (ja) * | 2000-06-05 | 2003-12-02 | ドン・ア・ファーム・カンパニー・リミテッド | 新規なオキサゾリジノン誘導体及びその製造方法 |
| JP2005507386A (ja) * | 2001-09-11 | 2005-03-17 | アストラゼネカ アクチボラグ | 抗菌剤としてのオキサゾリジノン及び/又はイソオキサゾリン |
| JP2006515286A (ja) * | 2002-11-28 | 2006-05-25 | アストラゼネカ アクチボラグ | 抗細菌性化合物 |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006519247A (ja) * | 2003-03-01 | 2006-08-24 | アストラゼネカ アクチボラグ | 抗生物質として有用なヒドロキシメチル置換ジヒドロイソオキサゾール誘導体 |
| JP2007500708A (ja) * | 2003-07-29 | 2007-01-18 | リブ−エックス ファーマシューティカルズ,インコーポレイテッド | ビアリールオキサゾリジノンの合成方法 |
| JP2011137007A (ja) * | 2003-07-29 | 2011-07-14 | Rib-X Pharmaceuticals Inc | ビアリールオキサゾリジノンの合成方法 |
| JP4777246B2 (ja) * | 2003-07-29 | 2011-09-21 | リブ−エックス ファーマシューティカルズ,インコーポレイテッド | ビアリールオキサゾリジノンの合成方法 |
| JP2015505846A (ja) * | 2011-12-19 | 2015-02-26 | サウディ ベーシック インダストリーズ コーポレイション | メタロセン錯体を調製するプロセス |
| JP2015506916A (ja) * | 2011-12-19 | 2015-03-05 | サウディ ベーシック インダストリーズ コーポレイション | メタロセン錯体を調製するプロセス |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ540147A (en) | 2008-03-28 |
| US20060116400A1 (en) | 2006-06-01 |
| AU2003302404B2 (en) | 2008-06-19 |
| AU2003302404A1 (en) | 2004-06-18 |
| WO2004048392A1 (en) | 2004-06-10 |
| IL168747A0 (en) | 2009-02-11 |
| NO20052534L (no) | 2005-08-22 |
| EP1567532A1 (en) | 2005-08-31 |
| NO20052534D0 (no) | 2005-05-26 |
| HK1079794A1 (zh) | 2006-04-13 |
| CA2507468A1 (en) | 2004-06-10 |
| KR20050085193A (ko) | 2005-08-29 |
| MXPA05005651A (es) | 2005-07-27 |
| SA04250088A (ar) | 2005-12-03 |
| TW200533666A (en) | 2005-10-16 |
| BR0316688A (pt) | 2005-10-18 |
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