JP2006508132A5 - - Google Patents
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- Publication number
- JP2006508132A5 JP2006508132A5 JP2004551898A JP2004551898A JP2006508132A5 JP 2006508132 A5 JP2006508132 A5 JP 2006508132A5 JP 2004551898 A JP2004551898 A JP 2004551898A JP 2004551898 A JP2004551898 A JP 2004551898A JP 2006508132 A5 JP2006508132 A5 JP 2006508132A5
- Authority
- JP
- Japan
- Prior art keywords
- cannabinoid
- alkyl
- aryl sulfonate
- aryl
- substituted benzene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003557 cannabinoid Chemical class 0.000 claims 16
- 229930003827 cannabinoid Chemical class 0.000 claims 16
- 238000000034 method Methods 0.000 claims 14
- 125000005228 aryl sulfonate group Chemical group 0.000 claims 11
- 125000000217 alkyl group Chemical group 0.000 claims 7
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- 150000004996 alkyl benzenes Chemical group 0.000 claims 3
- 125000005233 alkylalcohol group Chemical group 0.000 claims 3
- 230000007062 hydrolysis Effects 0.000 claims 3
- 238000006460 hydrolysis reaction Methods 0.000 claims 3
- 230000003301 hydrolyzing effect Effects 0.000 claims 3
- 239000002184 metal Substances 0.000 claims 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 3
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 claims 2
- AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 claims 2
- 150000001335 aliphatic alkanes Chemical class 0.000 claims 2
- 150000001336 alkenes Chemical class 0.000 claims 2
- 150000001993 dienes Chemical class 0.000 claims 2
- ZXEKIIBDNHEJCQ-UHFFFAOYSA-N isobutanol Chemical compound CC(C)CO ZXEKIIBDNHEJCQ-UHFFFAOYSA-N 0.000 claims 2
- 229920006395 saturated elastomer Polymers 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 150000003512 tertiary amines Chemical class 0.000 claims 2
- BZLVMXJERCGZMT-UHFFFAOYSA-N Methyl tert-butyl ether Chemical compound COC(C)(C)C BZLVMXJERCGZMT-UHFFFAOYSA-N 0.000 claims 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 claims 1
- 229940065144 cannabinoids Drugs 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 239000013078 crystal Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- JMMWKPVZQRWMSS-UHFFFAOYSA-N isopropanol acetate Natural products CC(C)OC(C)=O JMMWKPVZQRWMSS-UHFFFAOYSA-N 0.000 claims 1
- 229940011051 isopropyl acetate Drugs 0.000 claims 1
- GWYFCOCPABKNJV-UHFFFAOYSA-N isovaleric acid Chemical compound CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 claims 1
- 240000004308 marijuana Species 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42554302P | 2002-11-12 | 2002-11-12 | |
| US43502702P | 2002-12-20 | 2002-12-20 | |
| PCT/US2003/035599 WO2004043946A1 (en) | 2002-11-12 | 2003-11-06 | Cannabinoid crystalline derivatives and process of cannabinoid purification |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006508132A JP2006508132A (ja) | 2006-03-09 |
| JP2006508132A5 true JP2006508132A5 (enExample) | 2007-02-22 |
Family
ID=32314593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004551898A Withdrawn JP2006508132A (ja) | 2002-11-12 | 2003-11-06 | カンナビノイド結晶性誘導体およびカンナビノイド精製方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7402686B2 (enExample) |
| EP (1) | EP1560819B1 (enExample) |
| JP (1) | JP2006508132A (enExample) |
| AT (1) | ATE410419T1 (enExample) |
| AU (1) | AU2003287585B2 (enExample) |
| CA (1) | CA2504743C (enExample) |
| DE (1) | DE60324011D1 (enExample) |
| DK (1) | DK1560819T3 (enExample) |
| ES (1) | ES2315548T3 (enExample) |
| MX (1) | MXPA05004966A (enExample) |
| PT (1) | PT1560819E (enExample) |
| SI (1) | SI1560819T1 (enExample) |
| WO (1) | WO2004043946A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1428526A1 (en) * | 2002-12-13 | 2004-06-16 | Rijksuniversiteit Groningen | Formulation for fast dissolution of lipophilic compounds |
| WO2006007734A1 (de) * | 2004-07-19 | 2006-01-26 | Cilag Ltd. | Verfahren zur gewinnung von reinem tetrahydrocannabinol |
| EA200701246A1 (ru) * | 2004-12-09 | 2008-06-30 | Инсис Терапьютикс, Инк. | Стабильные при комнатной температуре составы дронабинола |
| AU2012201041B2 (en) * | 2005-09-29 | 2012-12-06 | Albany Molecular Research, Inc. | Process for production of delta-9-tetrahydrocannabinol |
| EP2578577A1 (en) * | 2005-09-29 | 2013-04-10 | Albany Molecular Research, Inc. | Sulfonyl esters of tetrahydrocannabinol and derivatives thereof |
| CA2659775A1 (en) * | 2006-08-04 | 2008-02-14 | Insys Therapeutics Inc. | Aqueous dronabinol formulations |
| GB0702895D0 (en) * | 2007-02-14 | 2007-03-28 | Resolution Chemicals Ltd | Delta 9 tetrahydrocannabinol derivatives |
| GB0703284D0 (en) | 2007-02-20 | 2007-03-28 | Resolution Chemicals Ltd | Delta 9 - tetrahydrocannabinol processing |
| CA2698752A1 (en) * | 2007-08-06 | 2009-02-12 | Insys Therapeutics Inc. | Oral cannabinoid liquid formulations and methods of treatment |
| WO2009099868A1 (en) * | 2008-02-06 | 2009-08-13 | Mallinckrodt Inc. | Process for the preparation of (-) -delta 9-tetrahydrocannabinol |
| US9220294B2 (en) | 2014-02-11 | 2015-12-29 | Timothy McCullough | Methods and devices using cannabis vapors |
| US10821240B2 (en) | 2014-02-11 | 2020-11-03 | Vapor Cartridge Technology Llc | Methods and drug delivery devices using cannabis |
| US9380813B2 (en) | 2014-02-11 | 2016-07-05 | Timothy McCullough | Drug delivery system and method |
| US9539295B2 (en) | 2014-12-05 | 2017-01-10 | Bradley Michael Bohus | Cannabidiol (CBD) enriched alcohol |
| US9585867B2 (en) | 2015-08-06 | 2017-03-07 | Charles Everett Ankner | Cannabinod formulation for the sedation of a human or animal |
| US10239808B1 (en) | 2016-12-07 | 2019-03-26 | Canopy Holdings, LLC | Cannabis extracts |
| US10272360B2 (en) | 2017-08-05 | 2019-04-30 | Priya Naturals, Inc. | Phytochemical extraction system and methods to extract phytochemicals from plants including plants of the family Cannabaceae sensu stricto |
| EP3745884A1 (en) | 2018-01-31 | 2020-12-09 | Canopy Holdings, Llc | Hemp powder |
| US10897925B2 (en) | 2018-07-27 | 2021-01-26 | Joseph Pandolfino | Articles and formulations for smoking products and vaporizers |
| US20200035118A1 (en) | 2018-07-27 | 2020-01-30 | Joseph Pandolfino | Methods and products to facilitate smokers switching to a tobacco heating product or e-cigarettes |
| US11040932B2 (en) | 2018-10-10 | 2021-06-22 | Treehouse Biotech, Inc. | Synthesis of cannabigerol |
| GB201910389D0 (en) * | 2019-07-19 | 2019-09-04 | Gw Pharma Ltd | Novel compounds, methods for their manufacture, and uses thereof |
| US11925907B2 (en) | 2019-07-22 | 2024-03-12 | Canopy Growth Corporation | Continuous crystallization of cannabinoids in a stirred-tank reactor |
| WO2021055079A1 (en) | 2019-09-16 | 2021-03-25 | Vapor Cartridge Technology Llc | Drug delivery system with stackable substrates |
| JP2023512578A (ja) * | 2020-02-06 | 2023-03-27 | ロンドン ファーマシューティカルズ アンド リサーチ コーポレーション | Ｃアナビンオイド硫酸エステル、その塩及び用途 |
| AU2022362107A1 (en) * | 2021-10-11 | 2024-05-02 | Anebulo Pharmaceuticals, Inc. | Crystalline forms of a cannabinoid receptor type 1 (cb1) modulator and methods of use and preparation thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3636058A (en) | 1966-03-25 | 1972-01-18 | Hoffmann La Roche | 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones |
| US3507888A (en) | 1966-08-30 | 1970-04-21 | Searle & Co | Process and intermediates for manufacture of 17-oxygenated estr-4-en-3-ones |
| US3728360A (en) | 1971-08-31 | 1973-04-17 | Little Inc A | Ester derivatives of tetrahydrocannabinol |
| US4188495A (en) | 1977-11-14 | 1980-02-12 | Pfizer Inc. | 1,9-Dihydroxyoctahydrophenanthrenes and intermediates therefor |
| US4206225A (en) | 1978-09-22 | 1980-06-03 | Pfizer Inc. | 2,10-Disubstituted dibenzo[b,d]pyrans and benzo[c]quinolines |
| US4341906A (en) | 1979-09-24 | 1982-07-27 | Pfizer Inc. | 1,9-Dihydroxyoctahydrophenanthrenes |
| US4381399A (en) | 1981-12-21 | 1983-04-26 | Aerojet-General Corporation | Purification of tetrahydrodibenzo[b,d]pyrans from crude synthetic mixtures |
| GB9303911D0 (en) | 1993-02-26 | 1993-04-14 | Zeneca Ltd | Chemical process |
| JP3384163B2 (ja) * | 1994-11-09 | 2003-03-10 | 株式会社ニコン | 顕微鏡対物レンズ |
| US6008383A (en) | 1998-10-26 | 1999-12-28 | University Of Mississippi | Method of preparing delta-9-tetrahydrocannabinol esters |
| WO2006000734A1 (en) | 2004-06-23 | 2006-01-05 | Bp P.L.C. | The synthesis of the micro-porous silica gel and its application to the preparation of catalysts for c2 oxygenates synthesis from syngas |
-
2003
- 2003-11-06 DK DK03781830T patent/DK1560819T3/da active
- 2003-11-06 JP JP2004551898A patent/JP2006508132A/ja not_active Withdrawn
- 2003-11-06 SI SI200331388T patent/SI1560819T1/sl unknown
- 2003-11-06 US US10/533,576 patent/US7402686B2/en not_active Expired - Lifetime
- 2003-11-06 PT PT03781830T patent/PT1560819E/pt unknown
- 2003-11-06 MX MXPA05004966A patent/MXPA05004966A/es active IP Right Grant
- 2003-11-06 AU AU2003287585A patent/AU2003287585B2/en not_active Expired - Fee Related
- 2003-11-06 CA CA2504743A patent/CA2504743C/en not_active Expired - Fee Related
- 2003-11-06 ES ES03781830T patent/ES2315548T3/es not_active Expired - Lifetime
- 2003-11-06 DE DE60324011T patent/DE60324011D1/de not_active Expired - Lifetime
- 2003-11-06 EP EP03781830A patent/EP1560819B1/en not_active Expired - Lifetime
- 2003-11-06 AT AT03781830T patent/ATE410419T1/de not_active IP Right Cessation
- 2003-11-06 WO PCT/US2003/035599 patent/WO2004043946A1/en not_active Ceased
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