JP2006506947A5 - - Google Patents
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- Publication number
- JP2006506947A5 JP2006506947A5 JP2003584010A JP2003584010A JP2006506947A5 JP 2006506947 A5 JP2006506947 A5 JP 2006506947A5 JP 2003584010 A JP2003584010 A JP 2003584010A JP 2003584010 A JP2003584010 A JP 2003584010A JP 2006506947 A5 JP2006506947 A5 JP 2006506947A5
- Authority
- JP
- Japan
- Prior art keywords
- extender
- functional group
- target
- covalent bond
- tyrosine phosphatase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/121,216 US6998233B2 (en) | 1998-06-26 | 2002-04-10 | Methods for ligand discovery |
| US37703402P | 2002-05-01 | 2002-05-01 | |
| US10/374,499 US7214487B2 (en) | 1998-06-26 | 2003-02-25 | Methods for identifying compounds that modulate enzymatic activities by employing covalently bonded target-extender complexes with ligand candidates |
| PCT/US2003/006217 WO2003087054A2 (en) | 2002-04-10 | 2003-02-26 | Methods for identifying compounds that modulate enzymatic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006506947A JP2006506947A (ja) | 2006-03-02 |
| JP2006506947A5 true JP2006506947A5 (https=) | 2006-04-27 |
Family
ID=29255201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003584010A Ceased JP2006506947A (ja) | 2002-04-10 | 2003-02-26 | 酵素活性を調節する化合物を同定するための伸長係留アプローチ |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7214487B2 (https=) |
| EP (1) | EP1497450A4 (https=) |
| JP (1) | JP2006506947A (https=) |
| AU (2) | AU2003216468B2 (https=) |
| CA (1) | CA2478398A1 (https=) |
| WO (1) | WO2003087054A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335155B1 (en) * | 1998-06-26 | 2002-01-01 | Sunesis Pharmaceuticals, Inc. | Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules |
| PL229487B1 (pl) | 2002-11-12 | 2018-07-31 | Brigham & Womens Hospital Inc | Kompozycja zawierająca polimer β-1,6-glukozaminy, kompozycja zawierająca przeciwciało, kompozycja farmaceutyczna, sposób wytwarzania wyodrębnionego polisacharydu, sposób identyfikacji obecności deacetylowanej poli-N-acetyloglukozaminy (dPNAG) i/ lub poli-N-acetyloglukozaminy (PNAG), wyodrębniony polisacharyd do zastosowania w leczeniu lub profilaktyce zakażenia, wyodrębniony polisacharyd do zastosowania do wytwarzania przeciwciał, w tym przeciwciał monoklonalnych, wyodrębniony polisacharyd do zastosowania w identyfikacji przeciwciała monoklonalnego |
| US7736911B2 (en) * | 2004-04-15 | 2010-06-15 | Albert Einstein College Of Medicine Of Yeshiva University | Activity-based probes for protein tyrosine phosphatases |
| US8039194B2 (en) * | 2008-01-08 | 2011-10-18 | Internatinal Business Machines Corporation | Photoacid generators for extreme ultraviolet lithography |
| CN102159540B (zh) | 2008-07-21 | 2015-08-12 | 布赖汉姆妇女医院 | 与合成的β-1,6葡糖胺寡糖相关的方法和组合物 |
| US8394922B2 (en) | 2009-08-03 | 2013-03-12 | Medarex, Inc. | Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof |
| CN102939110A (zh) | 2010-04-21 | 2013-02-20 | 诺沃—诺迪斯克有限公司 | 蛋白质的选择性修饰 |
| US12397014B2 (en) | 2019-02-05 | 2025-08-26 | The Brigham And Women's Hospital, Inc. | Polysaccharide compositions for use in treating filariasis |
| CN114853629B (zh) * | 2021-02-03 | 2023-06-13 | 沈阳农业大学 | 一种二肽类化合物及其制备方法和应用 |
| JP7805983B2 (ja) | 2022-03-22 | 2026-01-26 | アッヴィ・インコーポレイテッド | ブルトン型チロシンキナーゼを分解するためのピリミジン |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5367058A (en) * | 1993-08-25 | 1994-11-22 | Becton, Dickinson And Company | Modified antibodies with increased affinity |
| US6998233B2 (en) * | 1998-06-26 | 2006-02-14 | Sunesis Pharmaceuticals, Inc. | Methods for ligand discovery |
| US6335155B1 (en) * | 1998-06-26 | 2002-01-01 | Sunesis Pharmaceuticals, Inc. | Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules |
| US6919178B2 (en) * | 2000-11-21 | 2005-07-19 | Sunesis Pharmaceuticals, Inc. | Extended tethering approach for rapid identification of ligands |
| CA2430234C (en) | 2000-11-21 | 2008-02-12 | Sunesis Pharmaceuticals, Inc. | An extended tethering approach for rapid identification of ligands |
| MXPA04001000A (es) | 2001-08-07 | 2004-06-25 | Sunesis Pharmaceuticals Inc | Mutantes de cisteina y metodos para detectar union de ligando a moleculas biologicas. |
| IL159983A0 (en) | 2001-08-07 | 2004-06-20 | Sunesis Pharmaceuticals Inc | Disulfide and thiosulfonate ligands and libraries comprising these ligands |
| MXPA04004814A (es) | 2001-11-21 | 2004-08-11 | Sunesis Pharmaceuticals Inc | Metodos para descubrir ligandos. |
-
2003
- 2003-02-25 US US10/374,499 patent/US7214487B2/en not_active Expired - Fee Related
- 2003-02-26 JP JP2003584010A patent/JP2006506947A/ja not_active Ceased
- 2003-02-26 WO PCT/US2003/006217 patent/WO2003087054A2/en not_active Ceased
- 2003-02-26 AU AU2003216468A patent/AU2003216468B2/en not_active Ceased
- 2003-02-26 EP EP03746539A patent/EP1497450A4/en not_active Withdrawn
- 2003-02-26 CA CA002478398A patent/CA2478398A1/en not_active Abandoned
-
2007
- 2007-04-16 US US11/735,944 patent/US20080220536A1/en not_active Abandoned
-
2008
- 2008-11-20 AU AU2008246264A patent/AU2008246264A1/en not_active Abandoned
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