JP2006506440A - 水溶性メソポルフィリン化合物および製造方法 - Google Patents

水溶性メソポルフィリン化合物および製造方法 Download PDF

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Publication number
JP2006506440A
JP2006506440A JP2004553902A JP2004553902A JP2006506440A JP 2006506440 A JP2006506440 A JP 2006506440A JP 2004553902 A JP2004553902 A JP 2004553902A JP 2004553902 A JP2004553902 A JP 2004553902A JP 2006506440 A JP2006506440 A JP 2006506440A
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Japan
Prior art keywords
mesoporphyrin
tin
compound
water
tin mesoporphyrin
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JP2004553902A
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English (en)
Japanese (ja)
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JP2006506440A5 (https=
Inventor
レヴィンソン，ベンジャミン
ドラモンド，ジョージ・エス
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ウェルスプリング・ファーマシューティカル・コーポレイション
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Publication of JP2006506440A publication Critical patent/JP2006506440A/ja
Publication of JP2006506440A5 publication Critical patent/JP2006506440A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/003—Compounds containing elements of Groups 4 or 14 of the Periodic Table without C-Metal linkages

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2004553902A 2002-11-20 2003-11-18 水溶性メソポルフィリン化合物および製造方法 Pending JP2006506440A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42785102P 2002-11-20 2002-11-20
PCT/US2003/036885 WO2004045546A2 (en) 2002-11-20 2003-11-18 Water-soluble mesoporphyrin compounds and methods of preparation

Publications (2)

Publication Number Publication Date
JP2006506440A true JP2006506440A (ja) 2006-02-23
JP2006506440A5 JP2006506440A5 (https=) 2007-01-11

Family

ID=32326603

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004553902A Pending JP2006506440A (ja) 2002-11-20 2003-11-18 水溶性メソポルフィリン化合物および製造方法

Country Status (6)

Country Link
US (1) US20040097481A1 (https=)
EP (1) EP1567165A4 (https=)
JP (1) JP2006506440A (https=)
AU (1) AU2003295618A1 (https=)
CA (1) CA2506081C (https=)
WO (1) WO2004045546A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010505853A (ja) * 2006-10-04 2010-02-25 インファケア ファーマスーティカル，コーポレイション スタンソポルフィンの高純度で大規模な製造
JP2011511766A (ja) * 2008-01-21 2011-04-14 ドゥルマディス エスアー 皮膚病の治療におけるセリンプロテアーゼ阻害剤の使用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7375216B2 (en) * 2002-06-04 2008-05-20 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin compounds
AU2003237349B2 (en) * 2002-06-04 2010-06-03 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin halide compounds
US20060222668A1 (en) * 2005-04-01 2006-10-05 Wellspring Pharmaceutical Corporation Stannsoporfin compositions, drug products and methods of manufacture
EP1865777A4 (en) * 2005-04-01 2008-07-16 Infacare Pharmaceutical Corp STANNSOPORFIN COMPOSITIONS AND ADMINISTRATION
US20080113955A1 (en) * 2006-10-04 2008-05-15 Benjamin Levinson Treatment of infant hyperbilirubinemia using low dosages of stannsoporfin
AU2012202684B2 (en) * 2006-10-04 2014-04-10 Mallinckrodt Hospital Products IP Limited High-purity large-scale preparation of stannsoporfin
PL2691398T3 (pl) 2011-03-30 2017-07-31 Infacare Pharmaceutical Corporation Sposoby syntezy mezoporfiryn metali

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62500787A (ja) * 1985-03-25 1987-04-02 ザ　ロツクフエラ−　ユニバ−シテイ 錫メリポルフィリンの治療的使用
WO1988004174A1 (en) * 1986-12-08 1988-06-16 The Rockefeller University Use of tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis
WO1997005152A1 (en) * 1995-08-02 1997-02-13 Warner-Lambert Company Amino acid complexes of cobalt (iii) mesoporphyrin ix and cobalt (iii) protoporphyrin ix
WO2001068099A1 (en) * 2000-03-10 2001-09-20 The Rockefeller University Modulation of cardiovascular injury

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US225264A (en) * 1880-03-09 Alpbed akeb
US4708964A (en) * 1984-02-09 1987-11-24 Chemex Pharmaceuticals Lipoxygenase inhibitors
US4692440A (en) * 1985-03-25 1987-09-08 The Rockefeller University Therapeutic use of tin mesoporphyrin
DE3827940A1 (de) * 1988-08-13 1990-03-01 Schering Ag 13,17-propionsaeure- und propionsaeurederivat- substituierte porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
US5912341A (en) * 1995-03-14 1999-06-15 Hoffman/Barrett, L.L.C. Heteroatom-functionalized porphyrazines and multimetallic complexes and polymers derived therefrom
CA2448570A1 (en) * 2001-05-31 2002-12-05 Miravant Pharmaceuticals, Inc. Substituted porphyrin and azaporphyrin derivatives and their use in photodynamic therapy, radioimaging and mri diagnosis
AU2003237349B2 (en) * 2002-06-04 2010-06-03 Infacare Pharmaceutical Corporation Preparation of metal mesoporphyrin halide compounds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62500787A (ja) * 1985-03-25 1987-04-02 ザ　ロツクフエラ−　ユニバ−シテイ 錫メリポルフィリンの治療的使用
WO1988004174A1 (en) * 1986-12-08 1988-06-16 The Rockefeller University Use of tin protoporphyrin and tin mesoporphyrin in the treatment of psoriasis
WO1997005152A1 (en) * 1995-08-02 1997-02-13 Warner-Lambert Company Amino acid complexes of cobalt (iii) mesoporphyrin ix and cobalt (iii) protoporphyrin ix
WO2001068099A1 (en) * 2000-03-10 2001-09-20 The Rockefeller University Modulation of cardiovascular injury

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010505853A (ja) * 2006-10-04 2010-02-25 インファケア ファーマスーティカル，コーポレイション スタンソポルフィンの高純度で大規模な製造
JP2014193839A (ja) * 2006-10-04 2014-10-09 Infacare Pharmaceutical Corp スタンソポルフィンの高純度で大規模な製造
JP2011511766A (ja) * 2008-01-21 2011-04-14 ドゥルマディス エスアー 皮膚病の治療におけるセリンプロテアーゼ阻害剤の使用

Also Published As

Publication number Publication date
US20040097481A1 (en) 2004-05-20
EP1567165A2 (en) 2005-08-31
CA2506081C (en) 2009-08-04
EP1567165A4 (en) 2006-10-18
WO2004045546A3 (en) 2004-07-08
WO2004045546A2 (en) 2004-06-03
CA2506081A1 (en) 2004-06-03
AU2003295618A1 (en) 2004-06-15

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