JP2006503638A5 - - Google Patents
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- Publication number
- JP2006503638A5 JP2006503638A5 JP2004546566A JP2004546566A JP2006503638A5 JP 2006503638 A5 JP2006503638 A5 JP 2006503638A5 JP 2004546566 A JP2004546566 A JP 2004546566A JP 2004546566 A JP2004546566 A JP 2004546566A JP 2006503638 A5 JP2006503638 A5 JP 2006503638A5
- Authority
- JP
- Japan
- Prior art keywords
- mixture
- xenon
- solvents
- hyperpolarized
- solvent mixtures
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 12
- 229910052724 xenon Inorganic materials 0.000 claims 12
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 11
- 239000002904 solvent Substances 0.000 claims 9
- 239000011877 solvent mixture Substances 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 239000002872 contrast media Substances 0.000 claims 2
- 230000002102 hyperpolarization Effects 0.000 claims 2
- 239000004615 ingredient Substances 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 238000005481 NMR spectroscopy Methods 0.000 claims 1
- 238000005388 cross polarization Methods 0.000 claims 1
- 150000002191 fatty alcohols Chemical class 0.000 claims 1
- 150000002194 fatty esters Chemical class 0.000 claims 1
- 238000007496 glass forming Methods 0.000 claims 1
- 239000008240 homogeneous mixture Substances 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 238000002595 magnetic resonance imaging Methods 0.000 claims 1
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 230000010287 polarization Effects 0.000 claims 1
- 238000010792 warming Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20025124A NO20025124D0 (no) | 2002-10-25 | 2002-10-25 | Metode |
| PCT/NO2003/000352 WO2004037296A2 (en) | 2002-10-25 | 2003-10-24 | Method for the production of hyperpolarized 129xe |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006503638A JP2006503638A (ja) | 2006-02-02 |
| JP2006503638A5 true JP2006503638A5 (https=) | 2006-10-26 |
| JP4420224B2 JP4420224B2 (ja) | 2010-02-24 |
Family
ID=19914117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004546566A Expired - Fee Related JP4420224B2 (ja) | 2002-10-25 | 2003-10-24 | 過分極１２９Ｘｅの製造法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8003077B2 (https=) |
| EP (1) | EP1583563B1 (https=) |
| JP (1) | JP4420224B2 (https=) |
| KR (1) | KR20050074495A (https=) |
| CN (1) | CN100435852C (https=) |
| AT (1) | ATE337796T1 (https=) |
| CA (1) | CA2500542A1 (https=) |
| DE (1) | DE60308066T2 (https=) |
| ES (1) | ES2274272T3 (https=) |
| NO (1) | NO20025124D0 (https=) |
| RU (1) | RU2337059C2 (https=) |
| WO (1) | WO2004037296A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3998243B2 (ja) * | 2003-01-10 | 2007-10-24 | 東横化学株式会社 | 核スピン偏極キセノンガスの製造方法及び製造装置 |
| CA2622347C (en) * | 2005-04-06 | 2011-01-25 | Mallinckrodt Inc. | Systems and methods for managing information relating to medical fluids and containers therefor |
| WO2007136439A2 (en) * | 2006-02-21 | 2007-11-29 | Avrum Belzer | Hyperpolarization methods, systems and compositions |
| US8703102B2 (en) | 2008-04-04 | 2014-04-22 | Millikelvin Technologies Llc | Systems and methods for producing hyperpolarized materials and mixtures thereof |
| US8623327B2 (en) | 2006-06-19 | 2014-01-07 | Beth Israel Deaconess Medical Center, Inc. | Imaging agents for use in magnetic resonance blood flow/perfusion imaging |
| US9289518B2 (en) * | 2008-08-22 | 2016-03-22 | The Brigham And Women's Hospital | Enhanced 13C NMR by thermal mixing with hyperpolarized 129XE |
| US8697034B2 (en) * | 2008-10-10 | 2014-04-15 | The Board Of Regents Of The University Of Texas System | Hyperpolarized 89-yttrium and methods relating thereto |
| US20100251732A1 (en) * | 2009-04-06 | 2010-10-07 | General Electric Company | Apparatus and method for introduction of a material into a cryogenic system |
| ES2375390B1 (es) * | 2009-10-26 | 2013-02-11 | Consejo Superior De Investigaciones Científicas (Csic) | Planta de recuperación de helio. |
| EP2348327B1 (en) * | 2010-01-18 | 2013-11-27 | Bruker BioSpin AG | Method for NMR measurements using dissolution dynamic nuclear polarization (DNP) with elimination of free radicals |
| CN101961051A (zh) * | 2010-09-08 | 2011-02-02 | 营口艾特科技有限公司 | 含氙气的液体及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9305349D0 (en) * | 1993-03-16 | 1993-05-05 | Nycomed Imaging As | Improvements in or relating to contrast agents |
| CN1224502A (zh) * | 1996-03-29 | 1999-07-28 | 劳伦斯·伯克利国家实验室 | 利用超极化惰性气体对于核磁共振和磁共振成象质量的提高 |
| IL126347A (en) * | 1996-03-29 | 2003-11-23 | Lawrence Berkeley National Lab | Enhancement of nmr and mri in the presence of hyperpolarized noble gases |
| JP2002508687A (ja) | 1997-06-19 | 2002-03-19 | ナイコムド イメージング エーエス | 磁気共鳴（ｍｒ）イメージング剤の生体外分極を含むオーバーハウザー磁気共鳴画像（ｏｒｍｉ）法 |
| US6278893B1 (en) | 1998-01-05 | 2001-08-21 | Nycomed Imaging As | Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent |
| US6125654A (en) * | 1998-10-16 | 2000-10-03 | Syracuse University | Bulk production and usage of hyperpolarized 129 Xenon |
| GB0001727D0 (en) * | 2000-01-25 | 2000-03-15 | Oxford Instr Uk Ltd | Hyperpolarization of a noble gas |
-
2002
- 2002-10-25 NO NO20025124A patent/NO20025124D0/no unknown
-
2003
- 2003-10-24 CN CNB2003801017512A patent/CN100435852C/zh not_active Expired - Fee Related
- 2003-10-24 CA CA002500542A patent/CA2500542A1/en not_active Abandoned
- 2003-10-24 US US10/532,563 patent/US8003077B2/en not_active Expired - Fee Related
- 2003-10-24 EP EP03759106A patent/EP1583563B1/en not_active Expired - Lifetime
- 2003-10-24 RU RU2005109267/15A patent/RU2337059C2/ru not_active IP Right Cessation
- 2003-10-24 ES ES03759106T patent/ES2274272T3/es not_active Expired - Lifetime
- 2003-10-24 JP JP2004546566A patent/JP4420224B2/ja not_active Expired - Fee Related
- 2003-10-24 KR KR1020057006967A patent/KR20050074495A/ko not_active Withdrawn
- 2003-10-24 AT AT03759106T patent/ATE337796T1/de not_active IP Right Cessation
- 2003-10-24 DE DE60308066T patent/DE60308066T2/de not_active Expired - Lifetime
- 2003-10-24 WO PCT/NO2003/000352 patent/WO2004037296A2/en not_active Ceased
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