JP4420224B2 - 過分極１２９Ｘｅの製造法 - Google Patents

過分極１２９Ｘｅの製造法 Download PDF

Info

Publication number
JP4420224B2
JP4420224B2 JP2004546566A JP2004546566A JP4420224B2 JP 4420224 B2 JP4420224 B2 JP 4420224B2 JP 2004546566 A JP2004546566 A JP 2004546566A JP 2004546566 A JP2004546566 A JP 2004546566A JP 4420224 B2 JP4420224 B2 JP 4420224B2
Authority
JP
Japan
Prior art keywords
xenon
mixture
solvents
hyperpolarized
dnp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2004546566A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006503638A (ja
JP2006503638A5 (https=
Inventor
アーデンクヤー−ラーセン，ヤン−ヘンリック
ハンソン，レナート
ヨハンセン，ハウクール
セルヴィン，ロルフ
ウィストランド，ラース−ゴラン
Original Assignee
ジーイー・ヘルスケア・アクスイェ・セルスカプ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジーイー・ヘルスケア・アクスイェ・セルスカプ filed Critical ジーイー・ヘルスケア・アクスイェ・セルスカプ
Publication of JP2006503638A publication Critical patent/JP2006503638A/ja
Publication of JP2006503638A5 publication Critical patent/JP2006503638A5/ja
Application granted granted Critical
Publication of JP4420224B2 publication Critical patent/JP4420224B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B23/00—Noble gases; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Atmospheric Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Semiconductor Lasers (AREA)
JP2004546566A 2002-10-25 2003-10-24 過分極１２９Ｘｅの製造法 Expired - Fee Related JP4420224B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20025124A NO20025124D0 (no) 2002-10-25 2002-10-25 Metode
PCT/NO2003/000352 WO2004037296A2 (en) 2002-10-25 2003-10-24 Method for the production of hyperpolarized 129xe

Publications (3)

Publication Number Publication Date
JP2006503638A JP2006503638A (ja) 2006-02-02
JP2006503638A5 JP2006503638A5 (https=) 2006-10-26
JP4420224B2 true JP4420224B2 (ja) 2010-02-24

Family

ID=19914117

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004546566A Expired - Fee Related JP4420224B2 (ja) 2002-10-25 2003-10-24 過分極１２９Ｘｅの製造法

Country Status (12)

Country Link
US (1) US8003077B2 (https=)
EP (1) EP1583563B1 (https=)
JP (1) JP4420224B2 (https=)
KR (1) KR20050074495A (https=)
CN (1) CN100435852C (https=)
AT (1) ATE337796T1 (https=)
CA (1) CA2500542A1 (https=)
DE (1) DE60308066T2 (https=)
ES (1) ES2274272T3 (https=)
NO (1) NO20025124D0 (https=)
RU (1) RU2337059C2 (https=)
WO (1) WO2004037296A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3998243B2 (ja) * 2003-01-10 2007-10-24 東横化学株式会社 核スピン偏極キセノンガスの製造方法及び製造装置
CA2622347C (en) * 2005-04-06 2011-01-25 Mallinckrodt Inc. Systems and methods for managing information relating to medical fluids and containers therefor
WO2007136439A2 (en) * 2006-02-21 2007-11-29 Avrum Belzer Hyperpolarization methods, systems and compositions
US8703102B2 (en) 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
US8623327B2 (en) 2006-06-19 2014-01-07 Beth Israel Deaconess Medical Center, Inc. Imaging agents for use in magnetic resonance blood flow/perfusion imaging
US9289518B2 (en) * 2008-08-22 2016-03-22 The Brigham And Women's Hospital Enhanced 13C NMR by thermal mixing with hyperpolarized 129XE
US8697034B2 (en) * 2008-10-10 2014-04-15 The Board Of Regents Of The University Of Texas System Hyperpolarized 89-yttrium and methods relating thereto
US20100251732A1 (en) * 2009-04-06 2010-10-07 General Electric Company Apparatus and method for introduction of a material into a cryogenic system
ES2375390B1 (es) * 2009-10-26 2013-02-11 Consejo Superior De Investigaciones Científicas (Csic) Planta de recuperación de helio.
EP2348327B1 (en) * 2010-01-18 2013-11-27 Bruker BioSpin AG Method for NMR measurements using dissolution dynamic nuclear polarization (DNP) with elimination of free radicals
CN101961051A (zh) * 2010-09-08 2011-02-02 营口艾特科技有限公司 含氙气的液体及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9305349D0 (en) * 1993-03-16 1993-05-05 Nycomed Imaging As Improvements in or relating to contrast agents
CN1224502A (zh) * 1996-03-29 1999-07-28 劳伦斯·伯克利国家实验室 利用超极化惰性气体对于核磁共振和磁共振成象质量的提高
IL126347A (en) * 1996-03-29 2003-11-23 Lawrence Berkeley National Lab Enhancement of nmr and mri in the presence of hyperpolarized noble gases
JP2002508687A (ja) 1997-06-19 2002-03-19 ナイコムド イメージング エーエス 磁気共鳴（ｍｒ）イメージング剤の生体外分極を含むオーバーハウザー磁気共鳴画像（ｏｒｍｉ）法
US6278893B1 (en) 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
US6125654A (en) * 1998-10-16 2000-10-03 Syracuse University Bulk production and usage of hyperpolarized 129 Xenon
GB0001727D0 (en) * 2000-01-25 2000-03-15 Oxford Instr Uk Ltd Hyperpolarization of a noble gas

Also Published As

Publication number Publication date
AU2003274845A1 (en) 2004-05-13
CA2500542A1 (en) 2004-05-06
JP2006503638A (ja) 2006-02-02
EP1583563A2 (en) 2005-10-12
DE60308066D1 (de) 2006-10-12
ES2274272T3 (es) 2007-05-16
WO2004037296A2 (en) 2004-05-06
CN1713925A (zh) 2005-12-28
NO20025124D0 (no) 2002-10-25
RU2337059C2 (ru) 2008-10-27
US8003077B2 (en) 2011-08-23
CN100435852C (zh) 2008-11-26
EP1583563B1 (en) 2006-08-30
KR20050074495A (ko) 2005-07-18
ATE337796T1 (de) 2006-09-15
US20060173282A1 (en) 2006-08-03
WO2004037296A3 (en) 2005-08-18
RU2005109267A (ru) 2005-12-10
DE60308066T2 (de) 2007-04-12

Similar Documents

Publication Publication Date Title
Pinon et al. Hyperpolarization via dissolution dynamic nuclear polarization: new technological and methodological advances
AU752308C (en) Method of magnetic resonance investigation
Kurdzesau et al. Dynamic nuclear polarization of small labelled molecules in frozen water–alcohol solutions
US6453188B1 (en) Method of magnetic resonance imaging
US20020058869A1 (en) Methods of magnetic resonance imaging (MRI) using contract agent solutions formed from the dissolution of hyperpolarised materials
US8703102B2 (en) Systems and methods for producing hyperpolarized materials and mixtures thereof
JP4420224B2 (ja) 過分極１２９Ｘｅの製造法
US6125654A (en) Bulk production and usage of hyperpolarized 129 Xenon
US20070025918A1 (en) Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization
US20110050228A1 (en) agent for transporting nuclear spin order and for magnetic resonance imaging
US20140223923A1 (en) Systems and methods for producing hyperpolarized materials and mixtures thereof
AU2010286413B2 (en) Systems and methods for producing hyperpolarized materials and mixtures thereof
AU2003274845B2 (en) Method for the production of hyperpolarized 129Xe
WO2000072031A1 (en) Methods of magnetic resonance imaging (mri) using contract agent solutions formed from the dissolution of hyperpolarised materials
EP2170406B1 (en) A method of hyperpolarizing a magnetic resonance agent
US9658300B1 (en) Method and apparatus for preparation of spin polarized reagents
Ardenkjaer-Larsen et al. Hyperpolarization via dissolution Dynamic Nuclear Polarization: new technological and methodological advances
HK1069635B (en) Method of magnetic resonance investigation

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060905

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060905

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20091020

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20091027

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20091124

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20091124

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20091124

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121211

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131211

Year of fee payment: 4

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees