CN100435852C - 超极化129Xe的制备方法 - Google Patents

超极化129Xe的制备方法 Download PDF

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Publication number
CN100435852C
CN100435852C CNB2003801017512A CN200380101751A CN100435852C CN 100435852 C CN100435852 C CN 100435852C CN B2003801017512 A CNB2003801017512 A CN B2003801017512A CN 200380101751 A CN200380101751 A CN 200380101751A CN 100435852 C CN100435852 C CN 100435852C
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CN
China
Prior art keywords
mixture
xenon
solvent
solvents
hyperpolarized
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Expired - Fee Related
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CNB2003801017512A
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English (en)
Chinese (zh)
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CN1713925A (zh
Inventor
J·-H·阿登克耶尔拉森
L·汉松
H·约翰尼松
R·赛尔文
L·-G·维斯特兰德
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GE Healthcare AS
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GE Healthcare AS
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    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B23/00—Noble gases; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Atmospheric Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Semiconductor Lasers (AREA)
CNB2003801017512A 2002-10-25 2003-10-24 超极化129Xe的制备方法 Expired - Fee Related CN100435852C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20025124A NO20025124D0 (no) 2002-10-25 2002-10-25 Metode
NO20025124 2002-10-25

Publications (2)

Publication Number Publication Date
CN1713925A CN1713925A (zh) 2005-12-28
CN100435852C true CN100435852C (zh) 2008-11-26

Family

ID=19914117

Family Applications (1)

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CNB2003801017512A Expired - Fee Related CN100435852C (zh) 2002-10-25 2003-10-24 超极化129Xe的制备方法

Country Status (12)

Country Link
US (1) US8003077B2 (https=)
EP (1) EP1583563B1 (https=)
JP (1) JP4420224B2 (https=)
KR (1) KR20050074495A (https=)
CN (1) CN100435852C (https=)
AT (1) ATE337796T1 (https=)
CA (1) CA2500542A1 (https=)
DE (1) DE60308066T2 (https=)
ES (1) ES2274272T3 (https=)
NO (1) NO20025124D0 (https=)
RU (1) RU2337059C2 (https=)
WO (1) WO2004037296A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101961051A (zh) * 2010-09-08 2011-02-02 营口艾特科技有限公司 含氙气的液体及其制备方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3998243B2 (ja) * 2003-01-10 2007-10-24 東横化学株式会社 核スピン偏極キセノンガスの製造方法及び製造装置
CA2622347C (en) * 2005-04-06 2011-01-25 Mallinckrodt Inc. Systems and methods for managing information relating to medical fluids and containers therefor
WO2007136439A2 (en) * 2006-02-21 2007-11-29 Avrum Belzer Hyperpolarization methods, systems and compositions
US8703102B2 (en) 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
US8623327B2 (en) 2006-06-19 2014-01-07 Beth Israel Deaconess Medical Center, Inc. Imaging agents for use in magnetic resonance blood flow/perfusion imaging
US9289518B2 (en) * 2008-08-22 2016-03-22 The Brigham And Women's Hospital Enhanced 13C NMR by thermal mixing with hyperpolarized 129XE
US8697034B2 (en) * 2008-10-10 2014-04-15 The Board Of Regents Of The University Of Texas System Hyperpolarized 89-yttrium and methods relating thereto
US20100251732A1 (en) * 2009-04-06 2010-10-07 General Electric Company Apparatus and method for introduction of a material into a cryogenic system
ES2375390B1 (es) * 2009-10-26 2013-02-11 Consejo Superior De Investigaciones Científicas (Csic) Planta de recuperación de helio.
EP2348327B1 (en) * 2010-01-18 2013-11-27 Bruker BioSpin AG Method for NMR measurements using dissolution dynamic nuclear polarization (DNP) with elimination of free radicals

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1224502A (zh) * 1996-03-29 1999-07-28 劳伦斯·伯克利国家实验室 利用超极化惰性气体对于核磁共振和磁共振成象质量的提高
US6125654A (en) * 1998-10-16 2000-10-03 Syracuse University Bulk production and usage of hyperpolarized 129 Xenon
WO2001055656A2 (en) * 2000-01-25 2001-08-02 Oxford Instruments Superconductivity Limited Hyperpolarization of a gas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9305349D0 (en) * 1993-03-16 1993-05-05 Nycomed Imaging As Improvements in or relating to contrast agents
IL126347A (en) * 1996-03-29 2003-11-23 Lawrence Berkeley National Lab Enhancement of nmr and mri in the presence of hyperpolarized noble gases
JP2002508687A (ja) 1997-06-19 2002-03-19 ナイコムド イメージング エーエス 磁気共鳴（ｍｒ）イメージング剤の生体外分極を含むオーバーハウザー磁気共鳴画像（ｏｒｍｉ）法
US6278893B1 (en) 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1224502A (zh) * 1996-03-29 1999-07-28 劳伦斯·伯克利国家实验室 利用超极化惰性气体对于核磁共振和磁共振成象质量的提高
US6125654A (en) * 1998-10-16 2000-10-03 Syracuse University Bulk production and usage of hyperpolarized 129 Xenon
WO2001055656A2 (en) * 2000-01-25 2001-08-02 Oxford Instruments Superconductivity Limited Hyperpolarization of a gas

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MRI of the Lungs Using Hyperpolarized Noble Gases. Harald E.Moller et al.MAGNETIC RESONANCE IN MEDICINE,Vol.47 . 2002 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101961051A (zh) * 2010-09-08 2011-02-02 营口艾特科技有限公司 含氙气的液体及其制备方法

Also Published As

Publication number Publication date
AU2003274845A1 (en) 2004-05-13
CA2500542A1 (en) 2004-05-06
JP2006503638A (ja) 2006-02-02
EP1583563A2 (en) 2005-10-12
DE60308066D1 (de) 2006-10-12
ES2274272T3 (es) 2007-05-16
JP4420224B2 (ja) 2010-02-24
WO2004037296A2 (en) 2004-05-06
CN1713925A (zh) 2005-12-28
NO20025124D0 (no) 2002-10-25
RU2337059C2 (ru) 2008-10-27
US8003077B2 (en) 2011-08-23
EP1583563B1 (en) 2006-08-30
KR20050074495A (ko) 2005-07-18
ATE337796T1 (de) 2006-09-15
US20060173282A1 (en) 2006-08-03
WO2004037296A3 (en) 2005-08-18
RU2005109267A (ru) 2005-12-10
DE60308066T2 (de) 2007-04-12

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Granted publication date: 20081126

Termination date: 20101024