JP2006503006A5 - - Google Patents
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- Publication number
- JP2006503006A5 JP2006503006A5 JP2004526742A JP2004526742A JP2006503006A5 JP 2006503006 A5 JP2006503006 A5 JP 2006503006A5 JP 2004526742 A JP2004526742 A JP 2004526742A JP 2004526742 A JP2004526742 A JP 2004526742A JP 2006503006 A5 JP2006503006 A5 JP 2006503006A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- alkenyl
- alkyl
- straight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 20
- 125000003342 alkenyl group Chemical group 0.000 claims 12
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 125000001424 substituent group Chemical group 0.000 claims 6
- 125000000304 alkynyl group Chemical group 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 239000000654 additive Substances 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 210000004748 cultured cell Anatomy 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 125000003161 (C1-C6) alkylene group Chemical group 0.000 claims 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 1
- 125000000041 C6-C10 aryl group Chemical group 0.000 claims 1
- 102000007987 Proto-Oncogene Proteins c-maf Human genes 0.000 claims 1
- 108010089507 Proto-Oncogene Proteins c-maf Proteins 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 150000001408 amides Chemical group 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 229940126585 therapeutic drug Drugs 0.000 claims 1
- 0 *CC(C1CC2C(*)C3C4)C(C5[C@@]6C5)C1C2C6[C@@]3C4c1cc(*)c(*)cc1 Chemical compound *CC(C1CC2C(*)C3C4)C(C5[C@@]6C5)C1C2C6[C@@]3C4c1cc(*)c(*)cc1 0.000 description 2
- RHENYUHFFDKIID-IBVNDQDKSA-N C[C@@](C[C@H]([C@@H]1CC(O)=O)[C@H]2[C@@H]1C=C1)([C@@H]2[C@@H]1C(c(cc1)cc2c1OCO2)=C1)[C@@H]1O Chemical compound C[C@@](C[C@H]([C@@H]1CC(O)=O)[C@H]2[C@@H]1C=C1)([C@@H]2[C@@H]1C(c(cc1)cc2c1OCO2)=C1)[C@@H]1O RHENYUHFFDKIID-IBVNDQDKSA-N 0.000 description 1
- OSPRSJBJLULHEO-UHFFFAOYSA-N OC(C(C1)C2C3C=CC4(CC(O)=O)C1C2C4)C=C3c(cc1)cc2c1OCO2 Chemical compound OC(C(C1)C2C3C=CC4(CC(O)=O)C1C2C4)C=C3c(cc1)cc2c1OCO2 OSPRSJBJLULHEO-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10235624A DE10235624A1 (de) | 2002-08-02 | 2002-08-02 | Endiandric acid H und ihre Derivate, Verfahren zu ihrer Herstellung und Verwendung derselben |
| PCT/EP2003/007821 WO2004014888A1 (de) | 2002-08-02 | 2003-07-18 | Endiandric acid h derivate als c-maf inhibitoren zur verwendung gegen asthma |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006503006A JP2006503006A (ja) | 2006-01-26 |
| JP2006503006A5 true JP2006503006A5 (https=) | 2006-08-31 |
| JP4598523B2 JP4598523B2 (ja) | 2010-12-15 |
Family
ID=30469404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004526742A Expired - Fee Related JP4598523B2 (ja) | 2002-08-02 | 2003-07-18 | 喘息に使用するｃ−ｍａｆ阻害剤としてのエンジアンドリック酸ｈ誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7019028B2 (https=) |
| EP (1) | EP1529040B1 (https=) |
| JP (1) | JP4598523B2 (https=) |
| AT (1) | ATE314359T1 (https=) |
| AU (1) | AU2003250099B2 (https=) |
| BR (1) | BR0313199A (https=) |
| CA (1) | CA2493483C (https=) |
| DE (2) | DE10235624A1 (https=) |
| DK (1) | DK1529040T3 (https=) |
| ES (1) | ES2254980T3 (https=) |
| IL (1) | IL166439A (https=) |
| MX (1) | MXPA05000387A (https=) |
| WO (1) | WO2004014888A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1944361A1 (en) | 2007-01-11 | 2008-07-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A method for expanding monocytes |
| CN108192972B (zh) | 2010-10-06 | 2022-09-09 | 生物医学研究机构基金会 | 用于乳腺癌转移的诊断、预后和治疗的方法 |
| EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
| BR112014030750A2 (pt) | 2012-06-06 | 2017-08-22 | Inst Catalana Recerca Estudis Avancats | Método para diagnóstico, prognóstico e tratamento da metástase do câncer pulmonar |
| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
| ES2906586T3 (es) | 2012-10-12 | 2022-04-19 | Inbiomotion Sl | Método para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de próstata |
| WO2015019125A1 (en) * | 2013-08-05 | 2015-02-12 | Societe De Developpement Et De Recherche Industrielle | Molecular targets for the treatment of wounds, in particular chronic wounds |
| US11596642B2 (en) | 2016-05-25 | 2023-03-07 | Inbiomotion S.L. | Therapeutic treatment of breast cancer based on c-MAF status |
| KR20200104298A (ko) | 2017-11-22 | 2020-09-03 | 인바이오모션 에스.엘. | c-MAF 상태에 기반한 유방암의 요법 치료 |
-
2002
- 2002-08-02 DE DE10235624A patent/DE10235624A1/de not_active Withdrawn
-
2003
- 2003-07-18 MX MXPA05000387A patent/MXPA05000387A/es active IP Right Grant
- 2003-07-18 EP EP03784025A patent/EP1529040B1/de not_active Expired - Lifetime
- 2003-07-18 DE DE50302084T patent/DE50302084D1/de not_active Expired - Lifetime
- 2003-07-18 WO PCT/EP2003/007821 patent/WO2004014888A1/de not_active Ceased
- 2003-07-18 ES ES03784025T patent/ES2254980T3/es not_active Expired - Lifetime
- 2003-07-18 AT AT03784025T patent/ATE314359T1/de active
- 2003-07-18 AU AU2003250099A patent/AU2003250099B2/en not_active Ceased
- 2003-07-18 CA CA2493483A patent/CA2493483C/en not_active Expired - Fee Related
- 2003-07-18 DK DK03784025T patent/DK1529040T3/da active
- 2003-07-18 JP JP2004526742A patent/JP4598523B2/ja not_active Expired - Fee Related
- 2003-07-18 BR BR0313199-8A patent/BR0313199A/pt not_active Application Discontinuation
- 2003-07-25 US US10/627,850 patent/US7019028B2/en not_active Expired - Fee Related
-
2005
- 2005-01-23 IL IL166439A patent/IL166439A/en not_active IP Right Cessation
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