JP2006501202A5 - - Google Patents
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- Publication number
- JP2006501202A5 JP2006501202A5 JP2004523753A JP2004523753A JP2006501202A5 JP 2006501202 A5 JP2006501202 A5 JP 2006501202A5 JP 2004523753 A JP2004523753 A JP 2004523753A JP 2004523753 A JP2004523753 A JP 2004523753A JP 2006501202 A5 JP2006501202 A5 JP 2006501202A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- independently
- group
- alkylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10233817A DE10233817A1 (de) | 2002-07-25 | 2002-07-25 | Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| PCT/EP2003/007891 WO2004011438A1 (de) | 2002-07-25 | 2003-07-18 | Diarylsubstituierte cyclische harnstoffderivate mit mch-modulatorischer wirkung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006501202A JP2006501202A (ja) | 2006-01-12 |
| JP2006501202A5 true JP2006501202A5 (cg-RX-API-DMAC10.html) | 2006-08-31 |
| JP4568113B2 JP4568113B2 (ja) | 2010-10-27 |
Family
ID=30128364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004523753A Expired - Fee Related JP4568113B2 (ja) | 2002-07-25 | 2003-07-18 | Ｍｃｈ調節作用を有するジアリール置換環状尿素誘導体 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1551810B1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP4568113B2 (cg-RX-API-DMAC10.html) |
| AR (1) | AR040514A1 (cg-RX-API-DMAC10.html) |
| AT (1) | ATE535513T1 (cg-RX-API-DMAC10.html) |
| AU (2) | AU2003257465A1 (cg-RX-API-DMAC10.html) |
| BR (1) | BR0312916A (cg-RX-API-DMAC10.html) |
| CA (1) | CA2493924A1 (cg-RX-API-DMAC10.html) |
| DE (1) | DE10233817A1 (cg-RX-API-DMAC10.html) |
| IL (1) | IL166471A (cg-RX-API-DMAC10.html) |
| MX (1) | MXPA05001048A (cg-RX-API-DMAC10.html) |
| MY (1) | MY142551A (cg-RX-API-DMAC10.html) |
| PE (1) | PE20040702A1 (cg-RX-API-DMAC10.html) |
| TW (1) | TW200408627A (cg-RX-API-DMAC10.html) |
| WO (2) | WO2004012648A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7241787B2 (en) | 2004-01-25 | 2007-07-10 | Sanofi-Aventis Deutschland Gmbh | Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments |
| DE102004003811A1 (de) * | 2004-01-25 | 2005-08-11 | Aventis Pharma Deutschland Gmbh | Substituierte N-Cyclohexylimidazolinone, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel |
| EP1727540A4 (en) * | 2004-03-23 | 2009-07-22 | Univ California | MELANIN-CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AND METHOD OF USE |
| WO2006015279A1 (en) * | 2004-07-28 | 2006-02-09 | Neurogen Corporation | Heterocyclic diamine compounds as ligands of the melanin concentrating hormone receptor useful for the treatment of obesity, diabetes, eating and sexual disorders |
| EP1634598A1 (en) * | 2004-09-07 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion |
| JP5250967B2 (ja) * | 2005-11-30 | 2013-07-31 | 三菱化学株式会社 | 有機化合物、電荷輸送材料、電荷輸送材料用組成物および有機電界発光素子 |
| KR101395615B1 (ko) * | 2005-11-30 | 2014-05-16 | 미쓰비시 가가꾸 가부시키가이샤 | 유기 화합물, 전하 수송 재료, 전하 수송 재료용 조성물 및유기 전계 발광 소자 |
| ES2412007T3 (es) | 2005-12-21 | 2013-07-09 | Janssen Pharmaceutica, N.V. | Derivados de pirazinona sustituida novedosos para uso en enfermedades mediadas por MCH-1 |
| AU2007214710A1 (en) * | 2006-02-15 | 2007-08-23 | Sanofi-Aventis | Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments |
| JP2010500300A (ja) | 2006-08-08 | 2010-01-07 | サノフィ−アベンティス | アリールアミノアリール−アルキル−置換イミダゾリジン−２，４−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用 |
| ES2483866T3 (es) | 2006-12-05 | 2014-08-08 | Janssen Pharmaceutica Nv | Derivados de diaza-espiro-piridinona sustituidos novedosos para uso en enfermedades mediadas por MCH-1 |
| WO2010003624A2 (en) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| DE102008049675A1 (de) | 2008-09-30 | 2010-04-01 | Markus Dr. Heinrich | Verfahren zur Herstellung von 3-Aminobiphenylen |
| US8410284B2 (en) | 2008-10-22 | 2013-04-02 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| WO2010051206A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| SG178880A1 (en) | 2009-08-26 | 2012-04-27 | Sanofi Sa | Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use |
| JP2013520502A (ja) | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| CA2826649C (en) | 2011-02-25 | 2016-07-26 | Merck Sharp & Dohme Corp. | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| US8846666B2 (en) | 2011-03-08 | 2014-09-30 | Sanofi | Oxathiazine derivatives which are substituted with benzyl or heteromethylene groups, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8809324B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683698B1 (de) | 2011-03-08 | 2017-10-04 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| RU2465895C1 (ru) * | 2011-09-08 | 2012-11-10 | Государственное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарева" | Способ лечения депрессивного невроза |
| US20140045746A1 (en) | 2012-08-02 | 2014-02-13 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| JP2016516004A (ja) | 2013-02-22 | 2016-06-02 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | 抗糖尿病二環式化合物 |
| WO2014139388A1 (en) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
| EP3010893B1 (de) | 2013-06-20 | 2019-10-02 | Bayer CropScience Aktiengesellschaft | Arylsulfid- und arylsulfoxid-derivate als akarizide und insektizide |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| EP3233077B1 (en) | 2014-12-19 | 2026-05-06 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
| EP3233799B1 (en) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
| WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| WO2018118670A1 (en) | 2016-12-20 | 2018-06-28 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
| EP3902805A4 (en) | 2018-12-28 | 2023-03-01 | SPV Therapeutics Inc. | CYCLINE-DEPENDENT KINASE INHIBITORS |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002649A3 (en) * | 1977-12-19 | 1979-07-11 | Sandoz Ag | 1-dimethyl-substituted alkyl-2- or 4-substituted phenylimidazoles, their production and their use as anti-obesity agents |
| DE4107857A1 (de) * | 1991-03-12 | 1992-09-17 | Thomae Gmbh Dr K | Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| CA2211458A1 (en) * | 1995-02-17 | 1996-08-22 | Kenji Okonogi | Azole compounds, their production and use |
| FR2764889B1 (fr) * | 1997-06-20 | 2000-09-01 | Sod Conseils Rech Applic | Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| US6054590A (en) * | 1998-03-25 | 2000-04-25 | Bristol-Myers Squibb Company | Imidazolone anorectic agents: II. phenyl derivatives |
| JP2002003370A (ja) * | 1999-09-20 | 2002-01-09 | Takeda Chem Ind Ltd | メラニン凝集ホルモン拮抗剤 |
| WO2002004433A2 (en) * | 2000-07-06 | 2002-01-17 | Neurogen Corporation | Melanin concentrating hormone receptor ligands |
| HUP0302966A2 (hu) * | 2000-07-31 | 2003-12-29 | Smithkline Beecham P.L.C. | Karboxamid-vegyületek és alkalmazásuk humán 11CBY receptor antagonistákként, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
| GT200100147A (es) * | 2000-07-31 | 2002-06-25 | Derivados de imidazol | |
| YU52403A (sh) * | 2000-12-26 | 2006-03-03 | Dr.Reddy's Research Foundation | Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže |
| GB0200283D0 (en) * | 2002-01-08 | 2002-02-20 | Smithkline Beecham Plc | Compounds |
-
2002
- 2002-07-25 DE DE10233817A patent/DE10233817A1/de not_active Withdrawn
-
2003
- 2003-07-15 AU AU2003257465A patent/AU2003257465A1/en not_active Abandoned
- 2003-07-15 WO PCT/EP2003/007639 patent/WO2004012648A2/de not_active Ceased
- 2003-07-18 JP JP2004523753A patent/JP4568113B2/ja not_active Expired - Fee Related
- 2003-07-18 AU AU2003251001A patent/AU2003251001B9/en not_active Ceased
- 2003-07-18 CA CA002493924A patent/CA2493924A1/en not_active Abandoned
- 2003-07-18 AT AT03771060T patent/ATE535513T1/de active
- 2003-07-18 BR BR0312916-0A patent/BR0312916A/pt not_active IP Right Cessation
- 2003-07-18 EP EP03771060A patent/EP1551810B1/de not_active Expired - Lifetime
- 2003-07-18 MX MXPA05001048A patent/MXPA05001048A/es active IP Right Grant
- 2003-07-18 WO PCT/EP2003/007891 patent/WO2004011438A1/de not_active Ceased
- 2003-07-21 PE PE2003000725A patent/PE20040702A1/es not_active Application Discontinuation
- 2003-07-23 TW TW092120029A patent/TW200408627A/zh unknown
- 2003-07-23 AR AR20030102644A patent/AR040514A1/es unknown
- 2003-07-23 MY MYPI20032759A patent/MY142551A/en unknown
-
2005
- 2005-01-17 IL IL166471A patent/IL166471A/en not_active IP Right Cessation
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