JP2006300944A - 液体を操作する装置及び方法 - Google Patents
液体を操作する装置及び方法 Download PDFInfo
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Abstract
【解決手段】両方の通路区分が毛細管ストップを橋絡するため又は解消するために互いに相対的に動かされること、特に接触させられること。
【選択図】図1
Description
2 液体
3 通路区分
4 通路区分
5 保持体区分
6 保持体区分
7 カバー
8 保持体
9 毛細管ストップ
10 案内装置
11 横縁
12 横縁
13 マイクロ構造
14 切欠き
15 反応領域
16 集合領域
17 保持体区分
18 保持体区分
19 結合区分
Claims (20)
- 液体(2)を操作するための装置(1)であって、第1の通路区分(3)と第2の通路区分(4)とを有し、液体(2)が第1の通路区分(3)から第2の通路区分(4)へ流れることができ、特に前記通路区分(3,4)の間に毛細管ストップ(9)が、前記第1の通路区分(3)から第2の通路区分(4)へ液体(2)が移動する前に、該液体(2)を一時的に抑留するために形成されている形式のものにおいて、両方の通路区分(3,4)が前記毛細管ストップ(9)を橋絡するか又は解消するために互いに相対的に運動可能及び/又は端面側で互いに接触可能であることを特徴とする、液体を操作する装置。
- 前記通路区分(3,4)が横断面で見て扁平に、方形にかつ/又は少なくとも開放側にて同じく構成されておりかつ/又は前記通路区分(3,4)又は該通路区分(3,4)を制限する保持体区分(5,6)が有利には一貫して剛性に構成されている、請求項1記載の装置。
- 前記通路区分(3,4)の主延在平面が少なくとも1つの共通な平面(E)に位置しかつ/又は前記第2の通路区分(4)が前記第1の通路区分(3)の延長又は継続通路区分を形成している、請求項1又は2記載の装置。
- 前記通路区分(3,4)が少なくとも2つの、互いに相対運動可能な保持体区分(5,6)と1つの共通の一貫したカバー(7)とから形成されている、請求項1から3までのいずれか1項記載の装置。
- 当該装置が少なくとも一方の保持体区分(5,6)を並進的に又は摺動可能に案内する案内装置(10)を有している、請求項4記載の装置。
- 毛細管ストップ(9)を橋絡するため又は解消するために前記保持体区分(5,6)の側面又は側縁(11,12)が、有利には全長に亙ってかつ/又は前記保持体区分(5,6)が端面側で接触又は接触可能である、請求項4又は5記載の装置。
- 前記通路区分(3,4)が並進的かつ/又は回転的に互いに相対的に運動可能、特に互いに相対的に摺動可能、変形可能、旋回可能かつ/又は屈曲可能である、請求項1から6までのいずれか1項記載の装置。
- 前記通路区分(3,4)又は該通路区分(3,4)を制限する前記保持体区分(5,6)が結合区分(19)を介して互いに結合され、該結合区分(19)が毛細管ストップ(9)を橋絡するか又は解消するために特に弾性的に変形可能である、請求項1から7までのいずれか1項記載の装置。
- 前記通路区分(3,4)又は該通路区分(3,4)を制限する前記保持体区分(5,6)が互いに端面側で接触させられるために旋回可能又は屈曲可能である、請求項1から8までのいずれか1項記載の装置。
- 前記通路区分(3,4)が前記液体(2)の流動方向又は該流動方向とは反対の方向にかつ/又は前記通路区分(3,4)の主延在平面にて互いに相対的に移動可能である、請求項1から9までのいずれか1項記載の装置。
- 前記第2の通路区分(14)にて当該液体に作用する毛細管力が前記第1の通路区分(3)にて当該液体に作用する毛細管力よりも大きい、請求項1から10までのいずれか1項記載の装置。
- 前記第1の通路区分(3)の横断面が前記毛細管ストップ(9)の前で、該毛細管ストップ(9)の後しろの前記第2の毛細管区分(4)の横断面に少なくともほぼ相応している、請求項1から11までのいずれか1項記載の装置。
- 前記毛細管ストップ(9)が前記第1の通路区分(3)を制限する少なくとも一方の側又は面に亙って、特に全幅に亙って延在しかつ/又は前記毛細管ストップ(9)が当該液体(2)の流動方向に対して横にかつ/又は前記第1又は第2の通路区分(3,4)の長手延在方向に対して横方向に延びている、請求項1から12までのいずれか1項記載の装置。
- 当該液体(2)が側壁なしで前記通路区分(3,4)にて案内されている、請求項1から13までのいずれか1項記載の装置。
- 第1の通路区分(3)から第2の通路区分(4)へ流れることができ、毛細管ストップ(9)で第1の通路区分(3)から第2の通路区分(4)へ移動する前に一時的に抑留される液体(2)を操作する方法において、両方の通路区分(3,4)を、前記毛管ストップ(9)を橋絡するため又は解消するために互いに相対的に移動させ、旋回させ、屈曲させかつ/又は変形させることを特徴とする、液体を操作するための方法。
- 毛細管ストップ(9)を橋絡するため又は解消するために前記通路区分(3,4)、特に対応する保持体区分(5,6)を接触させる、請求項15記載の方法。
- 前記毛細管ストップを橋絡するか又は解消するために前記通路区分が互いに相対的に移動させ、旋回させ、屈曲させかつ/又は変化させられる、請求項15又は16記載の方法。
- 前記毛細管ストップ(9)を橋絡するため又は解消するために前記通路区分(3,4)がほぼ該通路区分(3,4)の主延在平面にて互いに相対的に移動させられる、請求項15から17までのいずれか1項記載の方法。
- 複数の通路区分(3,4,17)間に形成された前記毛細管ストップ(9)を橋絡又は解消するために前記複数の通路区分(3,4,17)が選択的に相互に移動させられ、特に互いに接触させられる、請求項15から18までのいずれか1項記載の方法。
- 複数の通路区分(3,4,17)間に形成され毛細管ストップを橋絡又は解消するために複数の通路区分(3,4,17)が同時に又は順次互いに相対的に移動させられ、特に互いに接触させられる、請求項15から19までのいずれか1項記載の方法。
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Application Number | Priority Date | Filing Date | Title |
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DE102005017653.4 | 2005-04-15 | ||
DE102005017653A DE102005017653A1 (de) | 2005-04-15 | 2005-04-15 | Vorrichtung und Verfahren zur Manipulation einer Flüssigkeit |
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JP2006300944A true JP2006300944A (ja) | 2006-11-02 |
JP4813954B2 JP4813954B2 (ja) | 2011-11-09 |
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JP2006113802A Expired - Fee Related JP4813954B2 (ja) | 2005-04-15 | 2006-04-17 | 液体を操作する装置及び方法 |
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Country | Link |
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US (1) | US7655189B2 (ja) |
EP (1) | EP1714698B1 (ja) |
JP (1) | JP4813954B2 (ja) |
CN (1) | CN1865714B (ja) |
DE (1) | DE102005017653A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008126403A1 (ja) * | 2007-04-05 | 2008-10-23 | Panasonic Corporation | 試料液分析チップ |
JP2011513718A (ja) * | 2008-02-27 | 2011-04-28 | ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血漿の分離装置 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040265171A1 (en) * | 2003-06-27 | 2004-12-30 | Pugia Michael J. | Method for uniform application of fluid into a reactive reagent area |
US20140000223A1 (en) * | 2010-11-10 | 2014-01-02 | Boehringer Ingelheim Microparts Gmbh | Method for filling a blister packaging with liquid, and blister packaging with a cavity for filling with liquid |
US20140227148A1 (en) * | 2011-07-05 | 2014-08-14 | Boehringer Ingelheim Microparts Gmbh | Microfluidic Structure Having Recesses |
AU2013318647B2 (en) * | 2012-09-21 | 2017-10-26 | Massachusetts Institute Of Technology | Micro-fluidic device and uses thereof |
US11441701B2 (en) | 2017-07-14 | 2022-09-13 | Hewlett-Packard Development Company, L.P. | Microfluidic valve |
CN108831819A (zh) * | 2018-04-20 | 2018-11-16 | 中国药科大学 | 一种原态-变性转换离子源的设备及其应用 |
CA3148282A1 (en) | 2018-10-01 | 2020-04-09 | Pierre-Alexandre GOYETTE | System and method of fluid delivery |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4902629A (en) * | 1987-10-06 | 1990-02-20 | Personal Diagnostics, Inc. | Apparatus and processes for facilitating reaction between analyte and test reagent system |
JPH03505261A (ja) * | 1989-03-23 | 1991-11-14 | バンス,ロジャー・アブラハム | 液体移送装置 |
WO2004007078A1 (en) * | 2002-07-12 | 2004-01-22 | British Biocell International Limited | Lateral flow assay device and method |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE25009T1 (de) * | 1981-09-25 | 1987-02-15 | Winfried Dr Med Stoecker | Vorrichtung fuer photometrische analysen. |
JP3382632B2 (ja) * | 1992-03-13 | 2003-03-04 | オリンパス光学工業株式会社 | 生体関連物質の測定方法およびそれに用いる反応容器 |
GB9324310D0 (en) * | 1993-11-26 | 1994-01-12 | Univ Birmingham | Liquid transfer device |
US5766962A (en) * | 1995-12-22 | 1998-06-16 | Universal Healthwatch, Inc. | Device for collecting and testing samples |
US6822959B2 (en) * | 2000-07-31 | 2004-11-23 | Mindspeed Technologies, Inc. | Enhancing performance by pre-fetching and caching data directly in a communication processor's register set |
US6802342B2 (en) * | 2001-04-06 | 2004-10-12 | Fluidigm Corporation | Microfabricated fluidic circuit elements and applications |
EP1419818B1 (de) | 2002-11-14 | 2013-10-30 | Boehringer Ingelheim microParts GmbH | Vorrichtung zum schrittweisen Transport von Flüssigkeit unter Ausnutzung von Kapillarkräften |
TWI245739B (en) * | 2002-12-05 | 2005-12-21 | Ibm | Method and device for flowing a liquid on a surface |
DE10257004A1 (de) * | 2002-12-06 | 2004-06-17 | Steag Microparts Gmbh | Vorrichtung zur parallelen Dosierung von Flüssigkeiten |
DE10302720A1 (de) | 2003-01-23 | 2004-08-05 | Steag Microparts Gmbh | Mikrofluidischer Schalter zum Anhalten des Flüssigkeitsstroms während eines Zeitintervalls |
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- 2005-04-15 DE DE102005017653A patent/DE102005017653A1/de not_active Withdrawn
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- 2006-04-12 EP EP06007697A patent/EP1714698B1/de not_active Not-in-force
- 2006-04-13 CN CN2006100886465A patent/CN1865714B/zh not_active Expired - Fee Related
- 2006-04-17 JP JP2006113802A patent/JP4813954B2/ja not_active Expired - Fee Related
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4902629A (en) * | 1987-10-06 | 1990-02-20 | Personal Diagnostics, Inc. | Apparatus and processes for facilitating reaction between analyte and test reagent system |
JPH03505261A (ja) * | 1989-03-23 | 1991-11-14 | バンス,ロジャー・アブラハム | 液体移送装置 |
WO2004007078A1 (en) * | 2002-07-12 | 2004-01-22 | British Biocell International Limited | Lateral flow assay device and method |
Cited By (4)
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WO2008126403A1 (ja) * | 2007-04-05 | 2008-10-23 | Panasonic Corporation | 試料液分析チップ |
JP2011513718A (ja) * | 2008-02-27 | 2011-04-28 | ベーリンガー インゲルハイム マイクロパーツ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 血漿の分離装置 |
US9539572B2 (en) | 2008-02-27 | 2017-01-10 | Boehringer Ingelheim Microparts Gmbh | Apparatus for the separation of plasma |
US10363559B2 (en) | 2008-02-27 | 2019-07-30 | Boehringer Ingelheim International Gmbh | Apparatus for the separation of plasma |
Also Published As
Publication number | Publication date |
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CN1865714A (zh) | 2006-11-22 |
US7655189B2 (en) | 2010-02-02 |
US20060249387A1 (en) | 2006-11-09 |
JP4813954B2 (ja) | 2011-11-09 |
EP1714698A3 (de) | 2008-07-16 |
CN1865714B (zh) | 2010-12-08 |
EP1714698B1 (de) | 2012-12-19 |
EP1714698A2 (de) | 2006-10-25 |
DE102005017653A1 (de) | 2006-10-19 |
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