WO2008126403A1 - 試料液分析チップ - Google Patents

試料液分析チップ Download PDF

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Publication number
WO2008126403A1
WO2008126403A1 PCT/JP2008/000881 JP2008000881W WO2008126403A1 WO 2008126403 A1 WO2008126403 A1 WO 2008126403A1 JP 2008000881 W JP2008000881 W JP 2008000881W WO 2008126403 A1 WO2008126403 A1 WO 2008126403A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample liquid
analytical chip
wall surface
transfer channel
liquid analytical
Prior art date
Application number
PCT/JP2008/000881
Other languages
English (en)
French (fr)
Inventor
Tomohiro Yamamoto
Tetsuo Yukimasa
Ryou Hamada
Fumihisa Kitawaki
Nobuhiko Ozaki
Original Assignee
Panasonic Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panasonic Corporation filed Critical Panasonic Corporation
Priority to US12/593,986 priority Critical patent/US20100062414A1/en
Priority to JP2009508913A priority patent/JPWO2008126403A1/ja
Publication of WO2008126403A1 publication Critical patent/WO2008126403A1/ja

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/026Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0621Control of the sequence of chambers filled or emptied
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/043Hinged closures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0645Electrodes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0688Valves, specific forms thereof surface tension valves, capillary stop, capillary break
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49002Electrical device making
    • Y10T29/49117Conductor or circuit manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

 本発明は、簡易な構造でありながら隔離された反応領域と検出領域、および試料液の送液制御機構を有し、迅速で確実な分析が可能な試料液分析チップに関する。試料液分析チップは、両端が開放された管状の試料液移送路;ならびに前記試料液移送路の内壁面に配置された反応試薬層、および試料液の物理的あるいは化学的変化を検出するための検出領域を有する。試料液分析チップは、前記試料液移送路の壁面の一部に開口部および当該開口部と嵌合する蓋を有し、当該蓋の一部は前記壁面と蝶番を形成する。
PCT/JP2008/000881 2007-04-05 2008-04-04 試料液分析チップ WO2008126403A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/593,986 US20100062414A1 (en) 2007-04-05 2008-04-04 Sample liquid analytical chip
JP2009508913A JPWO2008126403A1 (ja) 2007-04-05 2008-04-04 試料液分析チップ

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-099693 2007-04-05
JP2007099693 2007-04-05

Publications (1)

Publication Number Publication Date
WO2008126403A1 true WO2008126403A1 (ja) 2008-10-23

Family

ID=39863563

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/000881 WO2008126403A1 (ja) 2007-04-05 2008-04-04 試料液分析チップ

Country Status (3)

Country Link
US (1) US20100062414A1 (ja)
JP (1) JPWO2008126403A1 (ja)
WO (1) WO2008126403A1 (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010175460A (ja) * 2009-01-30 2010-08-12 Seiko Epson Corp 反応場を有するデバイス
EP2480885A1 (en) * 2009-09-24 2012-08-01 Monash University Testing device for identifying antigens and antibodies in biofluids
WO2014049704A1 (ja) * 2012-09-26 2014-04-03 テルモ株式会社 測定用チップ
JP2014167489A (ja) * 2014-06-16 2014-09-11 Seiko Epson Corp 反応場を有するデバイスおよびセンサー
JP5628971B1 (ja) * 2013-06-13 2014-11-19 日本写真印刷株式会社 マイクロ流体デバイス及び誘電泳動装置
JP2016506509A (ja) * 2012-12-13 2016-03-03 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 流体ストップを備える流体システム
WO2016152225A1 (ja) * 2015-03-24 2016-09-29 テルモ株式会社 体液測定チップ及び成分測定装置セット
WO2019116476A1 (ja) * 2017-12-13 2019-06-20 株式会社ニコン 流体デバイス
WO2020079767A1 (ja) * 2018-10-17 2020-04-23 株式会社日立ハイテクノロジーズ 生化学用カートリッジ及び生化学分析装置
CN115427148A (zh) * 2021-02-05 2022-12-02 京东方科技集团股份有限公司 微流控芯片

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4985347B2 (ja) * 2007-11-21 2012-07-25 パナソニック株式会社 測定チップ
US9182353B2 (en) 2010-07-22 2015-11-10 Hach Company Lab-on-a-chip for alkalinity analysis
EP2602620A1 (en) * 2011-12-07 2013-06-12 Nxp B.V. An electronic lateral flow test arrangement and method
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument
US9739774B2 (en) 2015-09-03 2017-08-22 Nxp B.V. Substance detection device
IT201800006083A1 (it) * 2018-06-06 2019-12-06 Dispositivo microfluidico per la concentrazione di particelle tramite centrifugazione, e relativo dispositivo di centrifugazione e/o rilevazione
CN113495069B (zh) * 2021-04-19 2024-04-26 深圳市锦瑞生物科技股份有限公司 一种总胆固醇检测试剂及检测芯片

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006300944A (ja) * 2005-04-15 2006-11-02 Boehringer Ingelheim Microparts Gmbh 液体を操作する装置及び方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090087345A1 (en) * 2006-03-16 2009-04-02 Matsushita Electric Industrial Co., Ltd. Disk for liquid sample analysis
JPWO2007116909A1 (ja) * 2006-04-04 2009-08-20 パナソニック株式会社 試料液分析用パネル

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006300944A (ja) * 2005-04-15 2006-11-02 Boehringer Ingelheim Microparts Gmbh 液体を操作する装置及び方法

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010175460A (ja) * 2009-01-30 2010-08-12 Seiko Epson Corp 反応場を有するデバイス
EP2480885A1 (en) * 2009-09-24 2012-08-01 Monash University Testing device for identifying antigens and antibodies in biofluids
EP2480885A4 (en) * 2009-09-24 2013-04-03 Univ Monash ANALYSIS DEVICE FOR IDENTIFYING ANTIGENS AND ANTIBODIES IN BIOFLUIDS
WO2014049704A1 (ja) * 2012-09-26 2014-04-03 テルモ株式会社 測定用チップ
JP2016506509A (ja) * 2012-12-13 2016-03-03 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 流体ストップを備える流体システム
JP5628971B1 (ja) * 2013-06-13 2014-11-19 日本写真印刷株式会社 マイクロ流体デバイス及び誘電泳動装置
JP2015000355A (ja) * 2013-06-13 2015-01-05 日本写真印刷株式会社 マイクロ流体デバイス及び誘電泳動装置
JP2014167489A (ja) * 2014-06-16 2014-09-11 Seiko Epson Corp 反応場を有するデバイスおよびセンサー
WO2016152225A1 (ja) * 2015-03-24 2016-09-29 テルモ株式会社 体液測定チップ及び成分測定装置セット
WO2019116476A1 (ja) * 2017-12-13 2019-06-20 株式会社ニコン 流体デバイス
JPWO2019116476A1 (ja) * 2017-12-13 2021-01-28 株式会社ニコン 流体デバイス
JP7207325B2 (ja) 2017-12-13 2023-01-18 株式会社ニコン 流体デバイス
WO2020079767A1 (ja) * 2018-10-17 2020-04-23 株式会社日立ハイテクノロジーズ 生化学用カートリッジ及び生化学分析装置
GB2591369A (en) * 2018-10-17 2021-07-28 Hitachi High Tech Corp Biochemical cartridge and biochemical analysis device
JPWO2020079767A1 (ja) * 2018-10-17 2021-09-02 株式会社日立ハイテク 生化学用カートリッジ及び生化学分析装置
JP7022844B2 (ja) 2018-10-17 2022-02-18 株式会社日立ハイテク 生化学用カートリッジ及び生化学分析装置
GB2591369B (en) * 2018-10-17 2022-09-21 Hitachi High Tech Corp Biochemical cartridge and biochemical analysis device
CN115427148A (zh) * 2021-02-05 2022-12-02 京东方科技集团股份有限公司 微流控芯片
CN115427148B (zh) * 2021-02-05 2024-03-29 京东方科技集团股份有限公司 微流控芯片

Also Published As

Publication number Publication date
JPWO2008126403A1 (ja) 2010-07-22
US20100062414A1 (en) 2010-03-11

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