JP2005539128A5 - - Google Patents
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- Publication number
- JP2005539128A5 JP2005539128A5 JP2004537764A JP2004537764A JP2005539128A5 JP 2005539128 A5 JP2005539128 A5 JP 2005539128A5 JP 2004537764 A JP2004537764 A JP 2004537764A JP 2004537764 A JP2004537764 A JP 2004537764A JP 2005539128 A5 JP2005539128 A5 JP 2005539128A5
- Authority
- JP
- Japan
- Prior art keywords
- ophthalmic device
- hydrogel composition
- group
- hydrogel
- monomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 17
- 239000000017 hydrogel Substances 0.000 claims 14
- 239000000178 monomer Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 150000003839 salts Chemical class 0.000 claims 7
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 5
- 125000001153 fluoro group Chemical group F* 0.000 claims 5
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 claims 4
- 238000007334 copolymerization reaction Methods 0.000 claims 4
- 229920001296 polysiloxane Polymers 0.000 claims 4
- 230000036571 hydration Effects 0.000 claims 3
- 238000006703 hydration reaction Methods 0.000 claims 3
- 238000002513 implantation Methods 0.000 claims 3
- INQDDHNZXOAFFD-UHFFFAOYSA-N 2-[2-(2-prop-2-enoyloxyethoxy)ethoxy]ethyl prop-2-enoate Chemical compound C=CC(=O)OCCOCCOCCOC(=O)C=C INQDDHNZXOAFFD-UHFFFAOYSA-N 0.000 claims 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 2
- 210000004087 cornea Anatomy 0.000 claims 2
- 239000003431 cross linking reagent Substances 0.000 claims 2
- 238000003754 machining Methods 0.000 claims 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims 1
- ZXHDVRATSGZISC-UHFFFAOYSA-N 1,2-bis(ethenoxy)ethane Chemical compound C=COCCOC=C ZXHDVRATSGZISC-UHFFFAOYSA-N 0.000 claims 1
- QRIMLDXJAPZHJE-UHFFFAOYSA-N 2,3-dihydroxypropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCC(O)CO QRIMLDXJAPZHJE-UHFFFAOYSA-N 0.000 claims 1
- BJELTSYBAHKXRW-UHFFFAOYSA-N 2,4,6-triallyloxy-1,3,5-triazine Chemical compound C=CCOC1=NC(OCC=C)=NC(OCC=C)=N1 BJELTSYBAHKXRW-UHFFFAOYSA-N 0.000 claims 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- 229920000536 2-Acrylamido-2-methylpropane sulfonic acid Polymers 0.000 claims 1
- XHZPRMZZQOIPDS-UHFFFAOYSA-N 2-Methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid Chemical compound OS(=O)(=O)CC(C)(C)NC(=O)C=C XHZPRMZZQOIPDS-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- HWSSEYVMGDIFMH-UHFFFAOYSA-N 2-[2-[2-(2-methylprop-2-enoyloxy)ethoxy]ethoxy]ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCOCCOC(=O)C(C)=C HWSSEYVMGDIFMH-UHFFFAOYSA-N 0.000 claims 1
- AGBXYHCHUYARJY-UHFFFAOYSA-N 2-phenylethenesulfonic acid Chemical compound OS(=O)(=O)C=CC1=CC=CC=C1 AGBXYHCHUYARJY-UHFFFAOYSA-N 0.000 claims 1
- GQTFHSAAODFMHB-UHFFFAOYSA-N 2-prop-2-enoyloxyethanesulfonic acid Chemical compound OS(=O)(=O)CCOC(=O)C=C GQTFHSAAODFMHB-UHFFFAOYSA-N 0.000 claims 1
- NYUTUWAFOUJLKI-UHFFFAOYSA-N 3-prop-2-enoyloxypropane-1-sulfonic acid Chemical compound OS(=O)(=O)CCCOC(=O)C=C NYUTUWAFOUJLKI-UHFFFAOYSA-N 0.000 claims 1
- PENDLXYAEYGSTB-UHFFFAOYSA-N 5-(dimethylamino)pent-1-en-3-one Chemical compound CN(C)CCC(=O)C=C PENDLXYAEYGSTB-UHFFFAOYSA-N 0.000 claims 1
- 239000004641 Diallyl-phthalate Substances 0.000 claims 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- DAKWPKUUDNSNPN-UHFFFAOYSA-N Trimethylolpropane triacrylate Chemical compound C=CC(=O)OCC(CC)(COC(=O)C=C)COC(=O)C=C DAKWPKUUDNSNPN-UHFFFAOYSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- QUDWYFHPNIMBFC-UHFFFAOYSA-N bis(prop-2-enyl) benzene-1,2-dicarboxylate Chemical compound C=CCOC(=O)C1=CC=CC=C1C(=O)OCC=C QUDWYFHPNIMBFC-UHFFFAOYSA-N 0.000 claims 1
- 238000005266 casting Methods 0.000 claims 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N cinnamic acid Chemical compound OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 claims 1
- -1 cycloalkyl acrylates Chemical class 0.000 claims 1
- 230000010339 dilation Effects 0.000 claims 1
- AFOSIXZFDONLBT-UHFFFAOYSA-N divinyl sulfone Chemical compound C=CS(=O)(=O)C=C AFOSIXZFDONLBT-UHFFFAOYSA-N 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- XXMIOPMDWAUFGU-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO XXMIOPMDWAUFGU-UHFFFAOYSA-N 0.000 claims 1
- 239000003999 initiator Substances 0.000 claims 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 1
- 150000002734 metacrylic acid derivatives Chemical class 0.000 claims 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims 1
- WAUMXMQJIMQTJK-UHFFFAOYSA-N n,n'-dihydroxyocta-2,6-dienediamide Chemical compound ONC(=O)C=CCCC=CC(=O)NO WAUMXMQJIMQTJK-UHFFFAOYSA-N 0.000 claims 1
- 229940088644 n,n-dimethylacrylamide Drugs 0.000 claims 1
- YLGYACDQVQQZSW-UHFFFAOYSA-N n,n-dimethylprop-2-enamide Chemical compound CN(C)C(=O)C=C YLGYACDQVQQZSW-UHFFFAOYSA-N 0.000 claims 1
- OMNKZBIFPJNNIO-UHFFFAOYSA-N n-(2-methyl-4-oxopentan-2-yl)prop-2-enamide Chemical compound CC(=O)CC(C)(C)NC(=O)C=C OMNKZBIFPJNNIO-UHFFFAOYSA-N 0.000 claims 1
- ADTJPOBHAXXXFS-UHFFFAOYSA-N n-[3-(dimethylamino)propyl]prop-2-enamide Chemical compound CN(C)CCCNC(=O)C=C ADTJPOBHAXXXFS-UHFFFAOYSA-N 0.000 claims 1
- SLCVBVWXLSEKPL-UHFFFAOYSA-N neopentyl glycol Chemical compound OCC(C)(C)CO SLCVBVWXLSEKPL-UHFFFAOYSA-N 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000012744 reinforcing agent Substances 0.000 claims 1
- YODZTKMDCQEPHD-UHFFFAOYSA-N thiodiglycol Chemical compound OCCSCCO YODZTKMDCQEPHD-UHFFFAOYSA-N 0.000 claims 1
- 239000012745 toughening agent Substances 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
- LVLANIHJQRZTPY-UHFFFAOYSA-N vinyl carbamate Chemical compound NC(=O)OC=C LVLANIHJQRZTPY-UHFFFAOYSA-N 0.000 claims 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/246,242 US20040054026A1 (en) | 2002-09-18 | 2002-09-18 | Elastomeric, expandable hydrogel compositions |
| PCT/US2003/028442 WO2004026928A1 (en) | 2002-09-18 | 2003-09-10 | Elastomeric, expandable hydrogel compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005539128A JP2005539128A (ja) | 2005-12-22 |
| JP2005539128A5 true JP2005539128A5 (enExample) | 2006-08-24 |
Family
ID=31992288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004537764A Pending JP2005539128A (ja) | 2002-09-18 | 2003-09-10 | エラストマー系拡張可能ヒドロゲル組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040054026A1 (enExample) |
| EP (1) | EP1546225A1 (enExample) |
| JP (1) | JP2005539128A (enExample) |
| KR (1) | KR20050057384A (enExample) |
| CN (1) | CN1681862A (enExample) |
| AR (1) | AR041294A1 (enExample) |
| AU (1) | AU2003266026A1 (enExample) |
| CA (1) | CA2499504A1 (enExample) |
| TW (1) | TWI258488B (enExample) |
| WO (1) | WO2004026928A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060004165A1 (en) * | 2004-06-30 | 2006-01-05 | Phelan John C | Silicone hydrogels with lathability at room temperature |
| US9248614B2 (en) | 2004-06-30 | 2016-02-02 | Novartis Ag | Method for lathing silicone hydrogel lenses |
| KR20070114130A (ko) | 2005-02-14 | 2007-11-29 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | 착용감이 편안한 안용 장치 및 이의 제조방법 |
| CA2618035A1 (en) * | 2005-08-10 | 2007-02-15 | Novartis Ag | Silicone hydrogels |
| JP4496434B2 (ja) * | 2005-11-24 | 2010-07-07 | 信越化学工業株式会社 | 多官能（メタ）アクリレート化合物、光硬化性樹脂組成物及び物品 |
| JP5068765B2 (ja) * | 2005-12-14 | 2012-11-07 | ノバルティス アーゲー | シリコーンヒドロゲルの製造方法 |
| CA2651715C (en) | 2006-05-03 | 2015-03-24 | Vision Crc Limited | Ocular replacement material production method and the use thereof |
| AU2007247846A1 (en) * | 2006-05-03 | 2007-11-15 | Vision Crc Limited | Biological polysiloxanes |
| US20080076898A1 (en) * | 2006-09-27 | 2008-03-27 | Salamone Joseph C | Water soluble silicone macromonomers for ophthalmic materials |
| US7625598B2 (en) * | 2006-12-15 | 2009-12-01 | Bausch & Lomb Incorporated | Silicone contact lenses with wrinkled surface |
| US8329097B1 (en) * | 2009-01-22 | 2012-12-11 | Bausch & Lomb Incorporated | Sterilization of intraocular lenses |
| CN102115515B (zh) * | 2010-01-05 | 2014-06-18 | 远东新世纪股份有限公司 | 增进硅酮水胶润湿性的共聚物、包含其的硅酮水胶组合物及由此制得的眼用物品 |
| JP5720103B2 (ja) * | 2010-03-18 | 2015-05-20 | 東レ株式会社 | シリコーンハイドロゲル、眼用レンズおよびコンタクトレンズ |
| MX353647B (es) * | 2011-02-28 | 2018-01-15 | Coopervision Int Holding Co Lp | Lentes de contacto de hidrogel de silicona. |
| US9188702B2 (en) * | 2011-09-30 | 2015-11-17 | Johnson & Johnson Vision Care, Inc. | Silicone hydrogels having improved curing speed and other properties |
| CN103183830B (zh) * | 2011-12-29 | 2015-06-10 | 晶硕光学股份有限公司 | 亲水有机硅高聚物的制造方法 |
| TWI434865B (zh) | 2011-12-29 | 2014-04-21 | Pegavision Corp | 親水有機矽高聚物之製造方法 |
| US8940812B2 (en) * | 2012-01-17 | 2015-01-27 | Johnson & Johnson Vision Care, Inc. | Silicone polymers comprising sulfonic acid groups |
| ES2688532T3 (es) | 2013-01-18 | 2018-11-05 | Basf Se | Composiciones de recubrimiento a base de dispersión acrílica |
| JP6037453B2 (ja) * | 2013-11-14 | 2016-12-07 | 信越化学工業株式会社 | 眼科デバイス製造用モノマー |
| CN103955072A (zh) * | 2014-05-20 | 2014-07-30 | 丹阳市精通眼镜技术创新服务中心有限公司 | 一种使用遇水膨胀材料制作的防脱落眼镜 |
| CN106999628A (zh) * | 2014-12-16 | 2017-08-01 | 诺华股份有限公司 | 用于眼科装置的疏水性丙烯酸酯‑丙烯酰胺共聚物 |
| CN105061674B (zh) * | 2015-08-10 | 2018-04-13 | 爱生华(苏州)光学有限公司 | 一种新型含氟硅氧烷的硅水凝胶隐形眼镜的配方选择和新工艺 |
| KR101987303B1 (ko) * | 2016-11-23 | 2019-06-11 | 주식회사 인터로조 | 실록산 단량체, 이를 포함하는 중합조성물 및 이를 이용하여 제조된 실리콘 하이드로겔 렌즈 |
| EP3415117A1 (en) | 2017-06-15 | 2018-12-19 | Laser Vista AG | Intraocular lens implant |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3996189A (en) * | 1975-04-29 | 1976-12-07 | American Optical Corporation | Optically clear filled silicone elastomers |
| US3996187A (en) * | 1975-04-29 | 1976-12-07 | American Optical Corporation | Optically clear filled silicone elastomers |
| US4418165A (en) * | 1980-06-03 | 1983-11-29 | Dow Corning Corporation | Optically clear silicone compositions curable to elastomers |
| US4647282A (en) * | 1985-08-27 | 1987-03-03 | Moskovsky Nauchno-Issledovatelsky Institut Mikrokhirurgii Glaza | Material for ocular prosthetics |
| US4868251A (en) * | 1986-12-24 | 1989-09-19 | Allergan, Inc. | Ultraviolet light absorbing silicone compositions |
| US5512609A (en) * | 1992-04-14 | 1996-04-30 | Allergan, Inc. | Reinforced compositions and lens bodies made from same |
| JPH0632904A (ja) * | 1992-07-21 | 1994-02-08 | Asahi Chem Ind Co Ltd | 含フッ素シロキサン化合物 |
| US5321108A (en) * | 1993-02-12 | 1994-06-14 | Bausch & Lomb Incorporated | Fluorosilicone hydrogels |
| BR9612119A (pt) * | 1995-12-07 | 1999-02-17 | Bausch & Lomb | Unidade monomérica composição de hidrogel lente de contato e método para produzir uma composição de hidrogel |
| US6326448B1 (en) * | 1997-08-20 | 2001-12-04 | Menicon Co., Ltd. | Soft intraocular lens material |
| US6891010B2 (en) * | 2001-10-29 | 2005-05-10 | Bausch & Lomb Incorporated | Silicone hydrogels based on vinyl carbonate endcapped fluorinated side chain polysiloxanes |
-
2002
- 2002-09-18 US US10/246,242 patent/US20040054026A1/en not_active Abandoned
-
2003
- 2003-09-10 EP EP03797898A patent/EP1546225A1/en not_active Withdrawn
- 2003-09-10 CA CA002499504A patent/CA2499504A1/en not_active Abandoned
- 2003-09-10 JP JP2004537764A patent/JP2005539128A/ja active Pending
- 2003-09-10 AU AU2003266026A patent/AU2003266026A1/en not_active Abandoned
- 2003-09-10 CN CNA038221853A patent/CN1681862A/zh active Pending
- 2003-09-10 WO PCT/US2003/028442 patent/WO2004026928A1/en not_active Ceased
- 2003-09-17 TW TW092125635A patent/TWI258488B/zh not_active IP Right Cessation
- 2003-09-18 AR ARP030103379A patent/AR041294A1/es not_active Application Discontinuation
-
2005
- 2005-03-17 KR KR1020057004547A patent/KR20050057384A/ko not_active Withdrawn
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