|
ATE538794T1
(de)
|
1999-01-13 |
2012-01-15 |
Bayer Healthcare Llc |
Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
|
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
MXPA04007832A
(es)
|
2002-02-11 |
2005-09-08 |
Bayer Pharmaceuticals Corp |
Aril-ureas con actividad inhibitoria de angiogenesis.
|
|
US7557129B2
(en)
|
2003-02-28 |
2009-07-07 |
Bayer Healthcare Llc |
Cyanopyridine derivatives useful in the treatment of cancer and other disorders
|
|
CA2520009A1
(en)
*
|
2003-03-24 |
2004-10-07 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
Oxamide derivatives useful as raf-kinase inhibitors
|
|
WO2004113274A2
(en)
|
2003-05-20 |
2004-12-29 |
Bayer Pharmaceuticals Corporation |
Diaryl ureas with kinase inhibiting activity
|
|
WO2005002673A1
(en)
*
|
2003-07-03 |
2005-01-13 |
Astex Therapeutics Limited |
Raf kinase inhibitors
|
|
JPWO2005105743A1
(ja)
*
|
2004-04-28 |
2008-03-13 |
小野薬品工業株式会社 |
含窒素複素環化合物およびその医薬用途
|
|
CN101010315A
(zh)
|
2004-04-30 |
2007-08-01 |
拜耳制药公司 |
用于治疗癌症的取代的吡唑基脲衍生物
|
|
PL1778686T3
(pl)
|
2004-08-12 |
2009-04-30 |
Pfizer |
Pochodne triazolopirydynylosulfanylowe jako inhibitory kinazy MAP P38
|
|
ME01309B
(me)
*
|
2004-08-26 |
2013-12-20 |
Pfizer |
Pirazolom supstituirani heteroarilni spojevi kao inhibitori proteinskih kinaza
|
|
BR122020017756B1
(pt)
*
|
2004-08-26 |
2022-02-15 |
Pfizer Inc |
Uso de compostos de aminoeteroarila enantiomericamente puros na preparação de um medicamento para o tratamento de crescimento celular anormal em um mamífero
|
|
DOP2006000233A
(es)
*
|
2005-10-28 |
2007-06-15 |
Lilly Co Eli |
Inhibidores de cinasa
|
|
JP2007217322A
(ja)
*
|
2006-02-15 |
2007-08-30 |
Ube Ind Ltd |
慢性閉塞性肺疾患の治療又は予防のための医薬組成物
|
|
TWI417095B
(zh)
|
2006-03-15 |
2013-12-01 |
Janssen Pharmaceuticals Inc |
１，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途
|
|
UA93548C2
(uk)
|
2006-05-05 |
2011-02-25 |
Айерем Елелсі |
Сполуки та композиції як модулятори хеджхогівського сигнального шляху
|
|
DK2848610T3
(da)
*
|
2006-11-15 |
2017-11-06 |
Ym Biosciences Australia Pty |
Hæmmere af kinaseaktivitet
|
|
TW200845978A
(en)
|
2007-03-07 |
2008-12-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
|
|
TW200900065A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
|
|
KR20100014811A
(ko)
|
2007-04-20 |
2010-02-11 |
데시페라 파마슈티칼스, 엘엘씨. |
골수증식성 질환 및 기타 증식성 질환의 치료에 유용한 키나제 억제제
|
|
US8722894B2
(en)
|
2007-09-14 |
2014-05-13 |
Janssen Pharmaceuticals, Inc. |
1,3-disubstituted-4-phenyl-1H-pyridin-2-ones
|
|
US8252937B2
(en)
|
2007-09-14 |
2012-08-28 |
Janssen Pharmaceuticals, Inc. |
1,3-disubstituted 4-(aryl-X-phenyl)-1H-pyridin-2-ones
|
|
PL2203439T3
(pl)
|
2007-09-14 |
2011-06-30 |
Addex Pharmaceuticals Sa |
1',3'-dipodstawione-4-fenylo-3,4,5,6-tetrahydro-2H, 1'H-[1, 4']bipirydynylo-2'-ketony
|
|
RU2492170C9
(ru)
|
2007-11-14 |
2013-12-27 |
Орто-Макнейл-Янссен Фармасьютикалз, Инк. |
Имидазо[1,2-а]пиридиновые производные и их применение в качестве положительных аллостерических модуляторов рецепторов mglur2
|
|
JP5547194B2
(ja)
|
2008-09-02 |
2014-07-09 |
ジャンセン ファーマシューティカルズ， インコーポレイテッド． |
代謝型グルタミン酸受容体の調節因子としての３−アザビシクロ［３．１．０］ヘキシル誘導体
|
|
MY159230A
(en)
*
|
2008-10-02 |
2016-12-30 |
Respivert Ltd |
P38 map kinase inhibitors
|
|
RU2517181C2
(ru)
|
2008-10-16 |
2014-05-27 |
Орто-Макнейл-Янссен Фармасьютикалз, Инк. |
Производные индола и бензоморфолина в качестве модулятора метаботропных глутаматных рецепторов
|
|
WO2010060589A1
(en)
|
2008-11-28 |
2010-06-03 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc. |
Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
|
|
JP5670912B2
(ja)
*
|
2008-12-11 |
2015-02-18 |
レスピバート・リミテツド |
ｐ３８ＭＡＰキナーゼ阻害剤
|
|
WO2010073011A2
(en)
|
2008-12-23 |
2010-07-01 |
Betagenon Ab |
Compounds useful as medicaments
|
|
GB0905955D0
(en)
|
2009-04-06 |
2009-05-20 |
Respivert Ltd |
Novel compounds
|
|
CN102439008B
(zh)
|
2009-05-12 |
2015-04-29 |
杨森制药有限公司 |
1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途
|
|
MY153912A
(en)
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
1, 2, 4,-triazolo[4,3-a[pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
|
MY153913A
(en)
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
|
EP2264010A1
(de)
|
2009-06-03 |
2010-12-22 |
Bayer CropScience AG |
Hetarylamidine
|
|
EP2661435B1
(en)
|
2010-11-08 |
2015-08-19 |
Janssen Pharmaceuticals, Inc. |
1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS
|
|
PL2649069T3
(pl)
|
2010-11-08 |
2016-01-29 |
Janssen Pharmaceuticals Inc |
Pochodne 1,2,4-triazolo[4,3-a]pirydyny i ich zastosowanie jako dodatnich allosterycznych modulatorów receptorów mGluR2
|
|
CN103261195B
(zh)
|
2010-11-08 |
2015-09-02 |
杨森制药公司 |
1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
|
|
KR101415742B1
(ko)
*
|
2011-12-21 |
2014-07-04 |
영남대학교 산학협력단 |
6―아미노피리딘―3―올 유도체 또는 이의 약제학적 허용가능한 염 및 이를 유효성분으로 함유하는 혈관신생으로 인한 질환의 예방 또는 치료용 약학조성물
|
|
US9889139B2
(en)
|
2011-12-21 |
2018-02-13 |
Research Cooperation Foundation Of Yeungnam University |
Method of treating inflammatory bowel disease comprising administering a pharmaceutical composition comprising a 6-aminopyridin-3-ol compound or a pharmaceutically acceptable salt thereof as an active ingredient to a subject
|
|
US8461179B1
(en)
|
2012-06-07 |
2013-06-11 |
Deciphera Pharmaceuticals, Llc |
Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
|
|
EP3007689B1
(en)
|
2013-01-10 |
2018-03-07 |
Pulmokine, Inc. |
Non-selective kinase inhibitors
|
|
JO3368B1
(ar)
|
2013-06-04 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
|
|
JO3367B1
(ar)
|
2013-09-06 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
|
|
US9925184B2
(en)
|
2013-10-11 |
2018-03-27 |
Pulmokine, Inc. |
Spray-dry formulations
|
|
KR20220049612A
(ko)
|
2014-01-21 |
2022-04-21 |
얀센 파마슈티카 엔.브이. |
대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
|
|
HUE053734T2
(hu)
|
2014-01-21 |
2021-07-28 |
Janssen Pharmaceutica Nv |
2-es altípusú metabotróp glutamáterg receptor pozitív allosztérikus modulátorait tartalmazó kombinációk és alkalmazásuk
|
|
KR20180011843A
(ko)
|
2015-06-11 |
2018-02-02 |
바실리어 파마슈티카 인터내셔널 리미티드 |
유출-펌프 억제제 및 이의 치료적 용도
|
|
RU2763525C2
(ru)
|
2016-10-27 |
2021-12-30 |
Пульмокин, Инк. |
Комбинированная терапия для лечения легочной гипертензии
|
|
CN106866627B
(zh)
*
|
2017-01-24 |
2021-09-14 |
南方医科大学 |
3-(1-(氨基吡啶氧基)乙基)苯甲酰胺衍生物及其合成方法和应用
|
|
WO2019148005A1
(en)
*
|
2018-01-26 |
2019-08-01 |
Nurix Therapeutics, Inc. |
Inhibitors of cbl-b and methods of use thereof
|
|
IL276398B2
(en)
|
2018-01-31 |
2026-03-01 |
Deciphera Pharmaceuticals Llc |
Combination therapy for mastocytosis
|
|
KR102708177B1
(ko)
|
2018-01-31 |
2024-09-23 |
데시페라 파마슈티칼스, 엘엘씨. |
위장관 기질 종양의 치료를 위한 병용 요법
|
|
JP7034512B2
(ja)
*
|
2018-03-15 |
2022-03-14 |
フーチェン ハイシィ ファーマシューティカルズ シーオー．，エルティーディー |
キナーゼ阻害剤としてのヘテロアリール化合物
|
|
KR102234399B1
(ko)
*
|
2018-05-23 |
2021-04-05 |
아주대학교산학협력단 |
톨-유사 수용체 3/7/8/9 억제 기능이 있는 길항성 소분자 화합물 tac5 시리즈
|
|
WO2019225920A1
(ko)
*
|
2018-05-23 |
2019-11-28 |
아주대학교산학협력단 |
톨-유사 수용체 3/7/8/9 억제 기능이 있는 길항성 소분자 화합물 tac5 시리즈
|
|
EP3938363A1
(en)
|
2019-03-11 |
2022-01-19 |
Teva Pharmaceuticals International GmbH |
Solid state forms of ripretinib
|
|
EP3953346A1
(en)
|
2019-04-09 |
2022-02-16 |
Nurix Therapeutics, Inc. |
3-substituted piperidine compounds for cbl-b inhibition, and use of a cbl-b inhibitor in combination with a cancer vaccine and/or oncolytic virus
|
|
LT4013412T
(lt)
|
2019-08-12 |
2026-03-25 |
Deciphera Pharmaceuticals, Llc |
Ripretinibas, skirtas virškinamojo trakto stromos navikų gydymui
|
|
PT4013412T
(pt)
|
2019-08-12 |
2026-03-18 |
Deciphera Pharmaceuticals Llc |
Ripretinib para o tratamento de tumores estromais gastrointestinais
|
|
WO2021054804A1
(ko)
*
|
2019-09-20 |
2021-03-25 |
주식회사 오토텍바이오 |
신규한 p62 리간드 화합물, 이를 포함하는 단백질이상질환의 예방, 개선 또는 치료용 조성물
|
|
HRP20231699T1
(hr)
|
2019-12-30 |
2024-05-10 |
Deciphera Pharmaceuticals, Llc |
Formulacije inhibitora amorfne kinaze i postupci njihove primjene
|
|
CN115243681B
(zh)
|
2019-12-30 |
2024-08-16 |
德西费拉制药有限责任公司 |
1-(4-溴-5-(1-乙基-7-(甲氨基)-2-侧氧基-1,2-二氢-1,6-萘啶-3-基)-2-氟苯基)-3-苯基脲的组合物
|
|
KR20220130980A
(ko)
|
2021-03-19 |
2022-09-27 |
주식회사 오토텍바이오 |
벤질옥시 피리딘 유도체 및 그 용도
|
|
US11779572B1
(en)
|
2022-09-02 |
2023-10-10 |
Deciphera Pharmaceuticals, Llc |
Methods of treating gastrointestinal stromal tumors
|