JP2005538690A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005538690A5 JP2005538690A5 JP2003571309A JP2003571309A JP2005538690A5 JP 2005538690 A5 JP2005538690 A5 JP 2005538690A5 JP 2003571309 A JP2003571309 A JP 2003571309A JP 2003571309 A JP2003571309 A JP 2003571309A JP 2005538690 A5 JP2005538690 A5 JP 2005538690A5
- Authority
- JP
- Japan
- Prior art keywords
- ptx3
- seq
- derivative
- tumor
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004881 tumor cell Anatomy 0.000 claims 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 101100192405 Mus musculus Ptx3 gene Proteins 0.000 claims 5
- 229960005486 vaccine Drugs 0.000 claims 5
- 101001082142 Homo sapiens Pentraxin-related protein PTX3 Proteins 0.000 claims 4
- BFHAYPLBUQVNNJ-UHFFFAOYSA-N Pectenotoxin 3 Natural products OC1C(C)CCOC1(O)C1OC2C=CC(C)=CC(C)CC(C)(O3)CCC3C(O3)(O4)CCC3(C=O)CC4C(O3)C(=O)CC3(C)C(O)C(O3)CCC3(O3)CCCC3C(C)C(=O)OC2C1 BFHAYPLBUQVNNJ-UHFFFAOYSA-N 0.000 claims 4
- 102100027351 Pentraxin-related protein PTX3 Human genes 0.000 claims 4
- 208000024200 hematopoietic and lymphoid system neoplasm Diseases 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- 101100352284 Homo sapiens PITX3 gene Proteins 0.000 claims 3
- 101100031710 Homo sapiens PTX3 gene Proteins 0.000 claims 3
- 108700025763 PTX3 Proteins 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 2
- 239000002299 complementary DNA Substances 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000002062 proliferating effect Effects 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 108090001008 Avidin Proteins 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 229960002685 biotin Drugs 0.000 claims 1
- 235000020958 biotin Nutrition 0.000 claims 1
- 239000011616 biotin Substances 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000002738 chelating agent Substances 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 239000002502 liposome Substances 0.000 claims 1
- 210000001165 lymph node Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002RM000109A ITRM20020109A1 (it) | 2002-02-28 | 2002-02-28 | Derivati funzionali della pentraxina lunga ptx3 per preparare un vaccino autologo per la cura dei tumori. |
| PCT/IT2003/000104 WO2003072603A2 (en) | 2002-02-28 | 2003-02-25 | Long pentraxin ptx3 functional derivatives for preparing an autologous vaccine for the treatment of tumours |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005538690A JP2005538690A (ja) | 2005-12-22 |
| JP2005538690A5 true JP2005538690A5 (https=) | 2006-04-06 |
Family
ID=11456119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003571309A Pending JP2005538690A (ja) | 2002-02-28 | 2003-02-25 | 腫瘍の治療用の自己ワクチンの調製のための長いペントラキシンｐｔｘ３機能性誘導体 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090110666A1 (https=) |
| EP (1) | EP1478661A2 (https=) |
| JP (1) | JP2005538690A (https=) |
| KR (1) | KR20040099291A (https=) |
| AR (1) | AR038854A1 (https=) |
| AU (1) | AU2003214645A1 (https=) |
| CA (1) | CA2475526A1 (https=) |
| IT (1) | ITRM20020109A1 (https=) |
| MX (1) | MXPA04008217A (https=) |
| PL (1) | PL372719A1 (https=) |
| TW (1) | TWI293958B (https=) |
| WO (1) | WO2003072603A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20040858A1 (it) | 2004-04-29 | 2004-07-29 | Farma Dev S R L | Anticorpi monoclonali ibridomi metodo migliorato per determinare la proteina ptx3 e kit per detta determinazione |
| ITRM20040489A1 (it) * | 2004-10-08 | 2005-01-08 | Sigma Tau Ind Farmaceuti | Pentraxina lunga ptx3 deglicosilata o desialidata. |
| JP5427415B2 (ja) * | 2006-01-24 | 2014-02-26 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | Ｆｇｆ２結合性ペプチドおよびそれらの使用 |
| US9226960B2 (en) | 2010-04-16 | 2016-01-05 | Andrew B. Bush | FGF modulation of in vivo antibody production and humoral immunity |
| US8435525B1 (en) * | 2010-04-16 | 2013-05-07 | Andrew B. Bush | FGF modulation of in vivo antibody production and humoral immunity |
| TWI531375B (zh) | 2015-05-29 | 2016-05-01 | 國立成功大學 | 抑制癌細胞活性之短肽治療劑及含此之醫藥組成物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5849478A (en) * | 1986-08-14 | 1998-12-15 | Cashman; Daniel P. | Blocked-polymerase polynucleotide immunoassay method and kit |
| US5290551A (en) * | 1990-05-08 | 1994-03-01 | Thomas Jefferson University | Treatment of melanoma with a vaccine comprising irradiated autologous melanoma tumor cells conjugated to a hapten |
| IT1298487B1 (it) * | 1997-12-19 | 2000-01-10 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale, |
| IT1317927B1 (it) * | 2000-11-03 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni. |
| IT1317930B1 (it) * | 2000-11-08 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patalogie associate ad una alterata attivazione |
| US20020122820A1 (en) * | 2001-01-16 | 2002-09-05 | Hildebrand William H. | Soluble MHC artificial antigen presenting cells |
| US20040198655A1 (en) * | 2001-08-03 | 2004-10-07 | Alberto Mantovani | Use of long pentraxin ptx3 for treating female infertility |
| US7041648B2 (en) * | 2001-08-03 | 2006-05-09 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Compositions and methods for treating female fertility |
| ITRM20020191A1 (it) * | 2002-04-08 | 2003-10-08 | Sigma Tau Ind Farmaceuti | Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie tumorali associate ad una alterata att |
| US20040137544A1 (en) * | 2002-10-31 | 2004-07-15 | Roberto Latini | PTX3 as an early prognostic indicator of cardiovascular and cerebrovascular pathologies |
| ITRM20030596A1 (it) * | 2003-12-23 | 2005-06-24 | Sigma Tau Ind Farmaceuti | Uso di inibitori della pentraxina lunga ptx3, per la preparazione di un medicamento per la prevenzione e cura di patologie che rispondono all'inibizione dell'attivita' biologica di detta ptx3. |
| US20070023879A1 (en) * | 2005-07-29 | 2007-02-01 | Vinayak Pandey | Single unit heat sink, voltage regulator, and package solution for an integrated circuit |
-
2002
- 2002-02-28 IT IT2002RM000109A patent/ITRM20020109A1/it unknown
-
2003
- 2003-02-20 TW TW092103564A patent/TWI293958B/zh active
- 2003-02-25 AU AU2003214645A patent/AU2003214645A1/en not_active Abandoned
- 2003-02-25 WO PCT/IT2003/000104 patent/WO2003072603A2/en not_active Ceased
- 2003-02-25 JP JP2003571309A patent/JP2005538690A/ja active Pending
- 2003-02-25 CA CA002475526A patent/CA2475526A1/en not_active Abandoned
- 2003-02-25 EP EP03710225A patent/EP1478661A2/en not_active Withdrawn
- 2003-02-25 MX MXPA04008217A patent/MXPA04008217A/es unknown
- 2003-02-25 PL PL03372719A patent/PL372719A1/xx unknown
- 2003-02-25 US US10/506,046 patent/US20090110666A1/en not_active Abandoned
- 2003-02-25 KR KR10-2004-7013464A patent/KR20040099291A/ko not_active Ceased
- 2003-02-27 AR ARP030100642A patent/AR038854A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7328187B2 (ja) | がん及び感染症の治療方法並びに治療用組成物 | |
| JP5971945B2 (ja) | カチオン性脂質の鏡像異性体による免疫応答の刺激 | |
| ES2283070T3 (es) | Utilizacion de oligonucleotidos inmunoestimulantes para la prevencion o tratamiento del asma. | |
| JP2004515202A5 (https=) | ||
| US20090285901A1 (en) | Polyamino acid for use as adjuvant | |
| JP2003502283A5 (https=) | ||
| JP2006020648A5 (https=) | ||
| HU227944B1 (en) | Vaccines containing a saponin and a sterol | |
| PT662000E (pt) | Microparticulas transportando antigenes e a sua utilizacao para a inducao de respostas humorais ou celulares | |
| JPH01279842A (ja) | Ａ型及びｂ型肝炎混合アジュバントワクチン | |
| JP2024036364A (ja) | Ｉ型インターフェロン遺伝子を刺激するための方法及びカチオン性脂質を含む組成物 | |
| JP2002531521A5 (https=) | ||
| JP2005538690A5 (https=) | ||
| KR20250140108A (ko) | 호흡기 세포융합 바이러스 mRNA 백신 | |
| EP1758615A2 (en) | Combination treatment of cancer with elicitor of gene product expression and gene-product targeting agent | |
| CN108210510B (zh) | 一种小干扰核酸药物组合物及其用途 | |
| JP2008308440A (ja) | 癌治療用薬剤送達ビヒクルおよびその製造方法ならびにそれを用いた製剤 | |
| JP2002526380A (ja) | 癌関連ｍｕｃ−１ムチン誘発免疫抑制の治療におけるｍｕｃ−１誘導体とその使用法 | |
| TWI293958B (en) | Functional derivatives of the long pentraxin ptx3 for the preparation of an autologous vaccine for the treatment of tumours | |
| JP2003503042A5 (https=) | ||
| US8883989B2 (en) | Fractalkine binding polynucleotides and methods of use | |
| BR112019011262A2 (pt) | composição farmacêutica, métodos para induzir ou promover ativação de células t, para induzir ou promover uma resposta imune, para tratar câncer e para tratar uma infecção. | |
| JP2004519452A5 (https=) | ||
| CN112089833A (zh) | 一种普适性的CpG ODN纳米颗粒佐剂及其制备方法和应用 | |
| CN117797085B (zh) | 一种自组装hbv多肽纳米颗粒凝胶疫苗及其应用 |