JP2005538102A - 低下された架橋を示すゼラチンカプセル - Google Patents
低下された架橋を示すゼラチンカプセル Download PDFInfo
- Publication number
- JP2005538102A JP2005538102A JP2004524263A JP2004524263A JP2005538102A JP 2005538102 A JP2005538102 A JP 2005538102A JP 2004524263 A JP2004524263 A JP 2004524263A JP 2004524263 A JP2004524263 A JP 2004524263A JP 2005538102 A JP2005538102 A JP 2005538102A
- Authority
- JP
- Japan
- Prior art keywords
- composition
- dosage form
- capsule
- gelatin
- capsule shell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 239000007903 gelatin capsule Substances 0.000 title claims abstract description 36
- 230000002829 reductive effect Effects 0.000 title abstract description 7
- 239000000203 mixture Substances 0.000 claims abstract description 132
- 238000004519 manufacturing process Methods 0.000 claims abstract description 18
- 239000002775 capsule Substances 0.000 claims description 102
- -1 sulfite compound Chemical class 0.000 claims description 92
- 239000003814 drug Substances 0.000 claims description 80
- 229940079593 drug Drugs 0.000 claims description 77
- 108010010803 Gelatin Proteins 0.000 claims description 50
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- 239000008273 gelatin Substances 0.000 claims description 50
- 235000019322 gelatine Nutrition 0.000 claims description 50
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 26
- 238000010828 elution Methods 0.000 claims description 23
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- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 4
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- XNTLXAUHLBBEKP-UHFFFAOYSA-N 2-(3,4-difluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-(4-methylsulfonylphenyl)pyridazin-3-one Chemical compound O=C1C(OCCC(C)(O)C)=C(C=2C=CC(=CC=2)S(C)(=O)=O)C=NN1C1=CC=C(F)C(F)=C1 XNTLXAUHLBBEKP-UHFFFAOYSA-N 0.000 claims description 2
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Landscapes
- Health & Medical Sciences (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39986202P | 2002-07-31 | 2002-07-31 | |
| US39986302P | 2002-07-31 | 2002-07-31 | |
| US39977602P | 2002-07-31 | 2002-07-31 | |
| US39980802P | 2002-07-31 | 2002-07-31 | |
| PCT/US2003/024045 WO2004010974A2 (en) | 2002-07-31 | 2003-07-31 | Gelatin capsule exhibiting reduced cross-linking |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2005538102A true JP2005538102A (ja) | 2005-12-15 |
Family
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Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004524263A Abandoned JP2005538102A (ja) | 2002-07-31 | 2003-07-31 | 低下された架橋を示すゼラチンカプセル |
| JP2004524262A Withdrawn JP2005538994A (ja) | 2002-07-31 | 2003-07-31 | 貯蔵における安定な溶出プロファイルを維持可能な医薬剤型 |
| JP2004534259A Withdrawn JP2006500389A (ja) | 2002-07-31 | 2003-07-31 | 亜硫酸塩化合物を含有する医薬剤形 |
| JP2004524261A Withdrawn JP2005538993A (ja) | 2002-07-31 | 2003-07-31 | 薄膜を形成しにくいゼラチンカプセル |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004524262A Withdrawn JP2005538994A (ja) | 2002-07-31 | 2003-07-31 | 貯蔵における安定な溶出プロファイルを維持可能な医薬剤型 |
| JP2004534259A Withdrawn JP2006500389A (ja) | 2002-07-31 | 2003-07-31 | 亜硫酸塩化合物を含有する医薬剤形 |
| JP2004524261A Withdrawn JP2005538993A (ja) | 2002-07-31 | 2003-07-31 | 薄膜を形成しにくいゼラチンカプセル |
Country Status (7)
| Country | Link |
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| EP (4) | EP1526846A2 (enExample) |
| JP (4) | JP2005538102A (enExample) |
| AU (4) | AU2003257102A1 (enExample) |
| BR (4) | BR0313150A (enExample) |
| CA (4) | CA2493980A1 (enExample) |
| MX (4) | MXPA05000862A (enExample) |
| WO (4) | WO2004010972A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011084521A (ja) * | 2009-10-16 | 2011-04-28 | Toyo Capsule Kk | アゼラスチン塩酸塩含有カプセル剤 |
| WO2020009142A1 (ja) | 2018-07-04 | 2020-01-09 | キャプシュゲル・ベルジウム・エヌ・ヴィ | 白色化剤として界面活性剤又は界面活性剤と塩を含有する皮膜形成性組成物 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003103582A2 (en) | 2002-06-05 | 2003-12-18 | Ivax Corporation | Reduction of gelatin cross-linking |
| CN101142198B (zh) | 2005-02-17 | 2012-10-31 | 辛塔制药公司 | 用于治疗疾病的异*唑坎布雷它斯丁衍生物 |
| US7485323B2 (en) | 2005-05-31 | 2009-02-03 | Gelita Ag | Process for making a low molecular weight gelatine hydrolysate and gelatine hydrolysate compositions |
| ATE485033T1 (de) * | 2005-07-26 | 2010-11-15 | Nicox Sa | Pharmazeutische formulierung von nitrooxy- derivaten von nsar |
| US11364478B2 (en) * | 2019-05-22 | 2022-06-21 | Mezzimatic, LLC | Method of manufacturing throwable paintballs and paintballs made therefrom |
| KR20220077091A (ko) * | 2020-12-01 | 2022-06-08 | 주식회사 엘지화학 | 1-(3-시아노-1-아이소프로필-인돌-5-일)피라졸-4-카르복실산을 포함하는 안정한 경구용 제제 |
| CN113230241A (zh) * | 2021-06-11 | 2021-08-10 | 北京畅盛医药科技有限公司 | 三羟甲基氨基甲烷盐在治疗心脑血管病的药物中的应用 |
Family Cites Families (10)
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| JPS5115094B2 (enExample) * | 1972-11-01 | 1976-05-14 | ||
| US4349529A (en) * | 1980-04-14 | 1982-09-14 | E. R. Squibb & Sons, Inc. | Diagnostic and therapeutic capsules and method of producing |
| US4590183A (en) * | 1985-04-22 | 1986-05-20 | Sterling Drug Inc. | Gastric cytoprotection with sodium thiosulfate in oral administration of aspirin |
| FR2617047B1 (fr) * | 1987-06-23 | 1991-05-10 | Sanofi Sa | Composition de gelatine resistant au tannage, capsules a base de cette composition et leur application pharmaceutique, notamment au fenofibrate |
| JP2790659B2 (ja) * | 1989-06-30 | 1998-08-27 | 帝国臓器製薬株式会社 | ゼラチンカプセル剤 |
| KR100338851B1 (ko) * | 1994-03-15 | 2002-10-12 | 센주 세이야꾸 가부시키가이샤 | 프라노프로펜의안정화방법및안정한프라노프로펜약제 |
| IT1269583B (it) * | 1994-04-26 | 1997-04-08 | Bayer Italia Spa | Preparazioni farmaceutiche a base di una soluzione di ketoprofene in capsule di gelatina molle e metodo per la loro produzione |
| DK0695544T3 (da) * | 1994-08-05 | 2001-01-02 | Shionogi & Co | Hårde gelatinekapsler, der kan modstå denaturering, og fremgangsmåde til fremstilling heraf |
| US5620704A (en) * | 1994-11-07 | 1997-04-15 | Warner-Lambert Company | Process for stabilizing gelatin products |
| US7115565B2 (en) * | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
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2003
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- 2003-07-31 EP EP03772161A patent/EP1526846A2/en not_active Withdrawn
- 2003-07-31 JP JP2004524263A patent/JP2005538102A/ja not_active Abandoned
- 2003-07-31 EP EP03772160A patent/EP1526845A2/en not_active Withdrawn
- 2003-07-31 MX MXPA05000862A patent/MXPA05000862A/es not_active Application Discontinuation
- 2003-07-31 JP JP2004524262A patent/JP2005538994A/ja not_active Withdrawn
- 2003-07-31 MX MXPA05001272A patent/MXPA05001272A/es unknown
- 2003-07-31 CA CA002493980A patent/CA2493980A1/en not_active Abandoned
- 2003-07-31 MX MXPA05001167A patent/MXPA05001167A/es unknown
- 2003-07-31 JP JP2004534259A patent/JP2006500389A/ja not_active Withdrawn
- 2003-07-31 AU AU2003257102A patent/AU2003257102A1/en not_active Abandoned
- 2003-07-31 WO PCT/US2003/024042 patent/WO2004010972A2/en not_active Ceased
- 2003-07-31 CA CA002493974A patent/CA2493974A1/en not_active Abandoned
- 2003-07-31 JP JP2004524261A patent/JP2005538993A/ja not_active Withdrawn
- 2003-07-31 CA CA002494069A patent/CA2494069A1/en not_active Abandoned
- 2003-07-31 WO PCT/US2003/024045 patent/WO2004010974A2/en not_active Ceased
- 2003-07-31 EP EP03794452A patent/EP1526847A2/en not_active Withdrawn
- 2003-07-31 WO PCT/US2003/024043 patent/WO2004010973A2/en not_active Ceased
- 2003-07-31 AU AU2003257982A patent/AU2003257982A1/en not_active Abandoned
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- 2003-07-31 AU AU2003257103A patent/AU2003257103A1/en not_active Abandoned
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011084521A (ja) * | 2009-10-16 | 2011-04-28 | Toyo Capsule Kk | アゼラスチン塩酸塩含有カプセル剤 |
| WO2020009142A1 (ja) | 2018-07-04 | 2020-01-09 | キャプシュゲル・ベルジウム・エヌ・ヴィ | 白色化剤として界面活性剤又は界面活性剤と塩を含有する皮膜形成性組成物 |
| US11801205B2 (en) | 2018-07-04 | 2023-10-31 | Capsugel Belgium Nv | Film-forming composition containing surfactant or surfactant and salt as whitening agent |
| US12303575B2 (en) | 2018-07-04 | 2025-05-20 | Capsugel Belgium Nv | Film-forming composition containing surfactant or surfactant and salt as whitening agent |
| US12419812B2 (en) | 2018-07-04 | 2025-09-23 | Capsugel Belgium Nv | Film-forming composition containing surfactant or surfactant and salt as whitening agent |
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