JP2005537283A - 胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア - Google Patents

胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア Download PDF

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Publication number
JP2005537283A
JP2005537283A JP2004524029A JP2004524029A JP2005537283A JP 2005537283 A JP2005537283 A JP 2005537283A JP 2004524029 A JP2004524029 A JP 2004524029A JP 2004524029 A JP2004524029 A JP 2004524029A JP 2005537283 A JP2005537283 A JP 2005537283A
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JP
Japan
Prior art keywords
aspiration
microspheres
gastroesophageal reflux
microns
diameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004524029A
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English (en)
Japanese (ja)
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JP2005537283A5 (enExample
Inventor
スプリンガー、チェイム
アヴィタル、アブラハム
スターン、テオドール
ベニータ、シモン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hadasit Medical Research Services and Development Co
Original Assignee
Hadasit Medical Research Services and Development Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Hadasit Medical Research Services and Development Co filed Critical Hadasit Medical Research Services and Development Co
Publication of JP2005537283A publication Critical patent/JP2005537283A/ja
Publication of JP2005537283A5 publication Critical patent/JP2005537283A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2004524029A 2002-07-25 2003-07-03 胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア Pending JP2005537283A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15090602A IL150906A0 (en) 2002-07-25 2002-07-25 Diagnostic microspheres
PCT/IL2003/000552 WO2004011035A2 (en) 2002-07-25 2003-07-03 Bio-degradable microspheres for diagnosing gastroesophagal reflux

Publications (2)

Publication Number Publication Date
JP2005537283A true JP2005537283A (ja) 2005-12-08
JP2005537283A5 JP2005537283A5 (enExample) 2006-08-24

Family

ID=29596364

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004524029A Pending JP2005537283A (ja) 2002-07-25 2003-07-03 胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア

Country Status (6)

Country Link
US (1) US8231860B2 (enExample)
EP (1) EP1575620B1 (enExample)
JP (1) JP2005537283A (enExample)
AU (1) AU2003242957A1 (enExample)
IL (1) IL150906A0 (enExample)
WO (1) WO2004011035A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020037100A (ja) * 2018-08-31 2020-03-12 ポール・コーポレーションPall Corporation 耐塩性アニオン交換媒体

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050283096A1 (en) 2004-06-17 2005-12-22 Bloorview Macmillan Children's Centre, A Corp. Registered Under The Ontario Corporations Act Apparatus and method for detecting swallowing activity
US9138171B2 (en) 2004-06-17 2015-09-22 Holland Bloorview Kids Rehabilitation Hospital System and method for detecting swallowing activity
EP2046397A2 (en) * 2006-07-19 2009-04-15 SmithKline Beecham Corporation Method for radiolabeling formulations for gamma scintigraphy assesment
US8992446B2 (en) 2009-06-21 2015-03-31 Holland Bloorview Kids Rehabilitation Hospital Procedure for denoising dual-axis swallowing accelerometry signals

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06504274A (ja) * 1991-01-07 1994-05-19 シンジェニックス・リミテッド 微細粒子
JPH06506254A (ja) * 1991-04-05 1994-07-14 イマアーレクス・フアーマシユーチカル・コーポレーシヨン 低密度の微細球およびコンピューター断層撮影用コントラスト剤としてのそれらの使用
JPH10273447A (ja) * 1997-01-29 1998-10-13 Takeda Chem Ind Ltd 徐放性マイクロスフィア、その製造法および用途
JP2002507976A (ja) * 1997-06-27 2002-03-12 ビーボウアールエックス ファーマスーティカルズ,インコーポレイテッド 薬理薬物の新規製剤、その製造法及びその使用法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2659554B1 (fr) 1990-03-16 1994-09-30 Oreal Composition pour le traitement cosmetique et/ou pharmaceutique des couches superieures de l'epiderme par application topique sur la peau et procede de preparation correspondant.
US5665383A (en) 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of immunostimulating agents for in vivo delivery
CA2263765C (en) 1996-08-19 2010-03-30 Vivorx Pharmaceuticals, Inc. Methods for the production of protein particles useful for delivery of pharmacological agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06504274A (ja) * 1991-01-07 1994-05-19 シンジェニックス・リミテッド 微細粒子
JPH06506254A (ja) * 1991-04-05 1994-07-14 イマアーレクス・フアーマシユーチカル・コーポレーシヨン 低密度の微細球およびコンピューター断層撮影用コントラスト剤としてのそれらの使用
JPH10273447A (ja) * 1997-01-29 1998-10-13 Takeda Chem Ind Ltd 徐放性マイクロスフィア、その製造法および用途
JP2002507976A (ja) * 1997-06-27 2002-03-12 ビーボウアールエックス ファーマスーティカルズ,インコーポレイテッド 薬理薬物の新規製剤、その製造法及びその使用法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
AVITAL,A. ET AL: "Charcoal is a sensitive, specific, and stable marker for the diagnosis of aspiration in hamsters", PEDIATR RES, vol. 51, no. 3, JPN6009043166, 2002, pages 397 - 401, XP002263602, ISSN: 0001401850 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020037100A (ja) * 2018-08-31 2020-03-12 ポール・コーポレーションPall Corporation 耐塩性アニオン交換媒体
JP7027673B2 (ja) 2018-08-31 2022-03-02 ポール・コーポレーション 耐塩性アニオン交換媒体

Also Published As

Publication number Publication date
AU2003242957A8 (en) 2004-02-16
WO2004011035A2 (en) 2004-02-05
WO2004011035B1 (en) 2004-04-29
AU2003242957A1 (en) 2004-02-16
US8231860B2 (en) 2012-07-31
US20050214216A1 (en) 2005-09-29
EP1575620B1 (en) 2012-09-26
EP1575620A2 (en) 2005-09-21
WO2004011035A3 (en) 2004-03-18
IL150906A0 (en) 2003-02-12

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