JP2005537283A - 胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア - Google Patents

胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア Download PDF

Info

Publication number
JP2005537283A
JP2005537283A JP2004524029A JP2004524029A JP2005537283A JP 2005537283 A JP2005537283 A JP 2005537283A JP 2004524029 A JP2004524029 A JP 2004524029A JP 2004524029 A JP2004524029 A JP 2004524029A JP 2005537283 A JP2005537283 A JP 2005537283A
Authority
JP
Japan
Prior art keywords
aspiration
microspheres
gastroesophageal reflux
microns
diameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004524029A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005537283A5 (enExample
Inventor
スプリンガー、チェイム
アヴィタル、アブラハム
スターン、テオドール
ベニータ、シモン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hadasit Medical Research Services and Development Co
Original Assignee
Hadasit Medical Research Services and Development Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Medical Research Services and Development Co filed Critical Hadasit Medical Research Services and Development Co
Publication of JP2005537283A publication Critical patent/JP2005537283A/ja
Publication of JP2005537283A5 publication Critical patent/JP2005537283A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2004524029A 2002-07-25 2003-07-03 胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア Pending JP2005537283A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15090602A IL150906A0 (en) 2002-07-25 2002-07-25 Diagnostic microspheres
PCT/IL2003/000552 WO2004011035A2 (en) 2002-07-25 2003-07-03 Bio-degradable microspheres for diagnosing gastroesophagal reflux

Publications (2)

Publication Number Publication Date
JP2005537283A true JP2005537283A (ja) 2005-12-08
JP2005537283A5 JP2005537283A5 (enExample) 2006-08-24

Family

ID=29596364

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004524029A Pending JP2005537283A (ja) 2002-07-25 2003-07-03 胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア

Country Status (6)

Country Link
US (1) US8231860B2 (enExample)
EP (1) EP1575620B1 (enExample)
JP (1) JP2005537283A (enExample)
AU (1) AU2003242957A1 (enExample)
IL (1) IL150906A0 (enExample)
WO (1) WO2004011035A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020037100A (ja) * 2018-08-31 2020-03-12 ポール・コーポレーションPall Corporation 耐塩性アニオン交換媒体

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050283096A1 (en) * 2004-06-17 2005-12-22 Bloorview Macmillan Children's Centre, A Corp. Registered Under The Ontario Corporations Act Apparatus and method for detecting swallowing activity
US9138171B2 (en) 2004-06-17 2015-09-22 Holland Bloorview Kids Rehabilitation Hospital System and method for detecting swallowing activity
JP2009543886A (ja) * 2006-07-19 2009-12-10 スミスクライン・ビーチャム・コーポレイション ガンマシンチグラフィー評価のために処方物を放射性標識する方法
US8992446B2 (en) 2009-06-21 2015-03-31 Holland Bloorview Kids Rehabilitation Hospital Procedure for denoising dual-axis swallowing accelerometry signals

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06504274A (ja) * 1991-01-07 1994-05-19 シンジェニックス・リミテッド 微細粒子
JPH06506254A (ja) * 1991-04-05 1994-07-14 イマアーレクス・フアーマシユーチカル・コーポレーシヨン 低密度の微細球およびコンピューター断層撮影用コントラスト剤としてのそれらの使用
JPH10273447A (ja) * 1997-01-29 1998-10-13 Takeda Chem Ind Ltd 徐放性マイクロスフィア、その製造法および用途
JP2002507976A (ja) * 1997-06-27 2002-03-12 ビーボウアールエックス ファーマスーティカルズ,インコーポレイテッド 薬理薬物の新規製剤、その製造法及びその使用法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2659554B1 (fr) * 1990-03-16 1994-09-30 Oreal Composition pour le traitement cosmetique et/ou pharmaceutique des couches superieures de l'epiderme par application topique sur la peau et procede de preparation correspondant.
US5665383A (en) 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of immunostimulating agents for in vivo delivery
EP0938299A4 (en) 1996-08-19 2001-01-17 Vivorx Pharmaceuticals Inc METHODS OF PRODUCING PROTEIN PARTICLES USEFUL IN THE DELIVERY OF PHARMACOLOGICAL AGENTS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06504274A (ja) * 1991-01-07 1994-05-19 シンジェニックス・リミテッド 微細粒子
JPH06506254A (ja) * 1991-04-05 1994-07-14 イマアーレクス・フアーマシユーチカル・コーポレーシヨン 低密度の微細球およびコンピューター断層撮影用コントラスト剤としてのそれらの使用
JPH10273447A (ja) * 1997-01-29 1998-10-13 Takeda Chem Ind Ltd 徐放性マイクロスフィア、その製造法および用途
JP2002507976A (ja) * 1997-06-27 2002-03-12 ビーボウアールエックス ファーマスーティカルズ,インコーポレイテッド 薬理薬物の新規製剤、その製造法及びその使用法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
AVITAL,A. ET AL: "Charcoal is a sensitive, specific, and stable marker for the diagnosis of aspiration in hamsters", PEDIATR RES, vol. 51, no. 3, JPN6009043166, 2002, pages 397 - 401, XP002263602, ISSN: 0001401850 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020037100A (ja) * 2018-08-31 2020-03-12 ポール・コーポレーションPall Corporation 耐塩性アニオン交換媒体
JP7027673B2 (ja) 2018-08-31 2022-03-02 ポール・コーポレーション 耐塩性アニオン交換媒体

Also Published As

Publication number Publication date
AU2003242957A8 (en) 2004-02-16
AU2003242957A1 (en) 2004-02-16
US20050214216A1 (en) 2005-09-29
EP1575620B1 (en) 2012-09-26
IL150906A0 (en) 2003-02-12
US8231860B2 (en) 2012-07-31
WO2004011035A3 (en) 2004-03-18
EP1575620A2 (en) 2005-09-21
WO2004011035A2 (en) 2004-02-05
WO2004011035B1 (en) 2004-04-29

Similar Documents

Publication Publication Date Title
AU608250B2 (en) Sustained-release particulate preparation and process for preparing the same
JP3381930B2 (ja) 超音波造影剤
US5238714A (en) Efficient microcapsule preparation and method of use
US20050019270A1 (en) Formulation of powder containing nanoparticles for aerosol delivery to the lungs
JP2011506077A (ja) 親水性活性化合物の送達のための中空多重層微小球
ES2527286T3 (es) Microesferas de liberación sostenida y métodos de fabricación y uso de las mismas
US9539334B2 (en) Orally dissolving thin films containing allergens and methods of making and use
CA2071867A1 (en) Method for producing protein microspheres
JP2004538347A (ja) 生分解性ポリマー組成物、及びその使用方法
PT785776E (pt) Preparacao de microesferas peliculas e revestimentos proteicos
CA2669745A1 (en) Method of producing microcapsules
WO2011088688A1 (zh) 以氨基酸为稳定剂的聚合物胶束载药系统
Jawahar et al. Nanoparticles: A novel pulmonary drug delivery system for tuberculosis
PT2140882E (pt) Agente para tratamento de doença pulmonar
Ali et al. Development and clinical trial of nano-atropine sulfate dry powder inhaler as a novel organophosphorous poisoning antidote
JP2008518007A (ja) 肺感染症の処置のための粒子
JP2005537283A (ja) 胃食道逆流(gastroesophagalreflux)診断用生分解性マイクロスフェア
CN109152842A (zh) 用于活性药物成分的基于蛋白质的赋形剂
JP2022104967A (ja) ポリマー肺サーファクタント
US8815294B2 (en) Pharmaceutical compositions of dextran polymer derivatives and a carrier material
CN109395093A (zh) 一种用于阿尔茨海默病的诊疗一体化制剂及其制备方法
JP4092587B2 (ja) 二軸混練機を用いた乾式コーティング
JP4707937B2 (ja) 薬物含有複合粒子の製造方法および経肺製剤
US20200261547A1 (en) Controlled release system for pulmonary delivery of surfactant protein d
BR112017000175B1 (pt) Método de preparação de uma insulina inalável adequada para a liberação pulmonar e partículas de insulina micronizadas

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060703

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060703

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090825

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091125

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091202

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091217

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100119