JP2005531601A5 - - Google Patents
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- Publication number
- JP2005531601A5 JP2005531601A5 JP2004509677A JP2004509677A JP2005531601A5 JP 2005531601 A5 JP2005531601 A5 JP 2005531601A5 JP 2004509677 A JP2004509677 A JP 2004509677A JP 2004509677 A JP2004509677 A JP 2004509677A JP 2005531601 A5 JP2005531601 A5 JP 2005531601A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally
- formula
- compound
- buten
- addition salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 8
- 239000002253 acid Substances 0.000 claims 7
- 150000003839 salts Chemical class 0.000 claims 6
- -1 1-buten-1-yl Chemical group 0.000 claims 5
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 239000007858 starting material Substances 0.000 claims 3
- 150000002148 esters Chemical class 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000001272 (C1-C4)-alkylene-phenyl group Chemical group 0.000 claims 1
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 claims 1
- 125000006017 1-propenyl group Chemical group 0.000 claims 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 1
- LERNTVKEWCAPOY-VOGVJGKGSA-N C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 Chemical compound C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 LERNTVKEWCAPOY-VOGVJGKGSA-N 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 230000000911 decarboxylating effect Effects 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 229960001361 ipratropium bromide Drugs 0.000 claims 1
- KEWHKYJURDBRMN-ZEODDXGYSA-M ipratropium bromide hydrate Chemical compound O.[Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 KEWHKYJURDBRMN-ZEODDXGYSA-M 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 229960000257 tiotropium bromide Drugs 0.000 claims 1
- 0 CN(C(CC(C1)OC(*)=O)C2O)C1C2O Chemical compound CN(C(CC(C1)OC(*)=O)C2O)C1C2O 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10224091A DE10224091A1 (de) | 2002-05-31 | 2002-05-31 | Technisches Verfahren zur Herstellung von Tropenol |
| PCT/EP2003/005158 WO2003101986A1 (de) | 2002-05-31 | 2003-05-16 | Technisches verfahren zur herstellung von tropenol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005531601A JP2005531601A (ja) | 2005-10-20 |
| JP2005531601A5 true JP2005531601A5 (https=) | 2006-07-13 |
| JP4610333B2 JP4610333B2 (ja) | 2011-01-12 |
Family
ID=29432472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004509677A Expired - Lifetime JP4610333B2 (ja) | 2002-05-31 | 2003-05-16 | トロペノールの工業的製法 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1513838B1 (https=) |
| JP (1) | JP4610333B2 (https=) |
| AT (1) | ATE334127T1 (https=) |
| AU (1) | AU2003224159A1 (https=) |
| CA (2) | CA2725704C (https=) |
| DE (2) | DE10224091A1 (https=) |
| DK (1) | DK1513838T3 (https=) |
| ES (1) | ES2268351T3 (https=) |
| WO (1) | WO2003101986A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2604742B1 (de) | 2011-12-13 | 2017-01-25 | Miele & Cie. KG | Bedienelement für ein Haushaltsgerät, Bedieneinheit für ein solches Haushaltsgerät mit einem solchen Bedienelement und Haushaltsgerät mit einer solchen Bedieneinheit und/ oder einem solchen Bedienelement |
| CN111269226B (zh) * | 2020-04-13 | 2021-09-21 | 石家庄四药有限公司 | 异丙托溴铵的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3931041C2 (de) * | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| DE4108393A1 (de) * | 1991-03-15 | 1992-09-17 | Boehringer Ingelheim Kg | Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln |
| DE10050994A1 (de) * | 2000-10-14 | 2002-04-18 | Boehringer Ingelheim Pharma | Neue als Arneimittel einsetzbare Anticholinergika sowie Verfahren zu deren Herstellung |
-
2002
- 2002-05-31 DE DE10224091A patent/DE10224091A1/de not_active Withdrawn
-
2003
- 2003-05-16 ES ES03720568T patent/ES2268351T3/es not_active Expired - Lifetime
- 2003-05-16 EP EP03720568A patent/EP1513838B1/de not_active Expired - Lifetime
- 2003-05-16 CA CA2725704A patent/CA2725704C/en not_active Expired - Fee Related
- 2003-05-16 DK DK03720568T patent/DK1513838T3/da active
- 2003-05-16 DE DE50304371T patent/DE50304371D1/de not_active Expired - Lifetime
- 2003-05-16 AT AT03720568T patent/ATE334127T1/de active
- 2003-05-16 AU AU2003224159A patent/AU2003224159A1/en not_active Abandoned
- 2003-05-16 WO PCT/EP2003/005158 patent/WO2003101986A1/de not_active Ceased
- 2003-05-16 JP JP2004509677A patent/JP4610333B2/ja not_active Expired - Lifetime
- 2003-05-16 CA CA2487672A patent/CA2487672C/en not_active Expired - Fee Related