JP2005530777A - 完全に線状の短鎖アルファー‐グルカン類の医薬用賦形剤としての使用 - Google Patents
完全に線状の短鎖アルファー‐グルカン類の医薬用賦形剤としての使用 Download PDFInfo
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- 239000011630 iodine Substances 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- TWNIBLMWSKIRAT-VFUOTHLCSA-N levoglucosan Chemical group O[C@@H]1[C@@H](O)[C@H](O)[C@H]2CO[C@@H]1O2 TWNIBLMWSKIRAT-VFUOTHLCSA-N 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 229960000907 methylthioninium chloride Drugs 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 150000004682 monohydrates Chemical class 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 235000019645 odor Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 230000004526 pharmaceutical effect Effects 0.000 description 1
- 230000026731 phosphorylation Effects 0.000 description 1
- 238000006366 phosphorylation reaction Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 description 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 description 1
- LJCNRYVRMXRIQR-OLXYHTOASA-L potassium sodium L-tartrate Chemical compound [Na+].[K+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O LJCNRYVRMXRIQR-OLXYHTOASA-L 0.000 description 1
- 229940074439 potassium sodium tartrate Drugs 0.000 description 1
- VZOPRCCTKLAGPN-ZFJVMAEJSA-L potassium;sodium;(2r,3r)-2,3-dihydroxybutanedioate;tetrahydrate Chemical compound O.O.O.O.[Na+].[K+].[O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O VZOPRCCTKLAGPN-ZFJVMAEJSA-L 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 238000000425 proton nuclear magnetic resonance spectrum Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000005204 segregation Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- OIIWPAYIXDCDNL-UHFFFAOYSA-M sodium 3-(trimethylsilyl)propionate Chemical compound [Na+].C[Si](C)(C)CCC([O-])=O OIIWPAYIXDCDNL-UHFFFAOYSA-M 0.000 description 1
- 229940047047 sodium arsenate Drugs 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 235000010344 sodium nitrate Nutrition 0.000 description 1
- 239000004317 sodium nitrate Substances 0.000 description 1
- 235000011006 sodium potassium tartrate Nutrition 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 229940045902 sodium stearyl fumarate Drugs 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 239000007916 tablet composition Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 238000003221 volumetric titration Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38050802P | 2002-05-14 | 2002-05-14 | |
| US10/298,813 US20030215499A1 (en) | 2002-05-14 | 2002-11-18 | Use of completely linear short chain alpha-glucans as a pharmaceutical excipient |
| PCT/US2003/014944 WO2003097017A1 (en) | 2002-05-14 | 2003-05-13 | Use of completely linear short chain alpha-glucans as a pharmaceutical excipient |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005530777A true JP2005530777A (ja) | 2005-10-13 |
| JP2005530777A5 JP2005530777A5 (https=) | 2006-06-29 |
Family
ID=29423266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004505016A Pending JP2005530777A (ja) | 2002-05-14 | 2003-05-13 | 完全に線状の短鎖アルファー‐グルカン類の医薬用賦形剤としての使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20030215499A1 (https=) |
| EP (1) | EP1503738A1 (https=) |
| JP (1) | JP2005530777A (https=) |
| AU (1) | AU2003234416A1 (https=) |
| WO (1) | WO2003097017A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008027904A (ja) * | 2006-06-26 | 2008-02-07 | Commissariat A L'energie Atomique | リチウム蓄電池電極用のデンプンならびにリチウムおよびチタン混合酸化物ベースを有する水性分散体 |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200507882A (en) * | 2003-07-17 | 2005-03-01 | Kyowa Hakko Kogyo Kk | Solid formulations |
| US7189288B2 (en) * | 2004-10-08 | 2007-03-13 | Tate & Lyle Ingredients Americas, Inc. | Enzyme-resistant starch and method for its production |
| US8318230B2 (en) * | 2005-05-02 | 2012-11-27 | Henkel Ag & Co. Kgaa | Use of debranched starch in extrusion-spheronization pharmaceutical pellets |
| US7276126B2 (en) * | 2005-06-03 | 2007-10-02 | Tate And Lyle Ingredients Americas, Inc. | Production of enzyme-resistant starch by extrusion |
| US7674897B2 (en) * | 2005-09-09 | 2010-03-09 | Tate & Lyle Ingredients Americas, Inc. | Production of crystalline short chain amylose |
| US7608436B2 (en) * | 2006-01-25 | 2009-10-27 | Tate & Lyle Ingredients Americas, Inc. | Process for producing saccharide oligomers |
| US8993039B2 (en) | 2006-01-25 | 2015-03-31 | Tate & Lyle Ingredients Americas Llc | Fiber-containing carbohydrate composition |
| US8057840B2 (en) * | 2006-01-25 | 2011-11-15 | Tate & Lyle Ingredients Americas Llc | Food products comprising a slowly digestible or digestion resistant carbohydrate composition |
| TWI727188B (zh) * | 2018-07-19 | 2021-05-11 | 大豐膠囊工業股份有限公司 | 解支酶改質澱粉，其製備方法及其於硬空膠囊製造上的應用 |
| US11540549B2 (en) | 2019-11-28 | 2023-01-03 | Tate & Lyle Solutions Usa Llc | High-fiber, low-sugar soluble dietary fibers, products including them and methods for using them |
| US12133918B2 (en) * | 2021-10-01 | 2024-11-05 | Griffin Gamma, Llc | Partially pre-gelatinized cassava starch as pharmaceutical excipient |
| CN115356291A (zh) * | 2022-09-13 | 2022-11-18 | 安徽皖维高新材料股份有限公司 | 一种采用阿贝折射仪快速测定四水合酒石酸钾钠纯度的方法 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04230637A (ja) * | 1990-12-27 | 1992-08-19 | Natl Starch & Chem Investment Holding Corp | タブレット賦形剤としての酵素的に枝切りされたデンプン |
| EP0499648A1 (en) * | 1990-12-17 | 1992-08-26 | National Starch and Chemical Investment Holding Corporation | Enzymatically debranched starches as tablet excipients |
| JPH08500490A (ja) * | 1992-08-28 | 1996-01-23 | エー．イー．ステーリー、マニュファクチュアリング、カンパニー | 低脂肪食品の製造方法 |
| JPH0856690A (ja) * | 1994-04-15 | 1996-03-05 | Cerestar Holding Bv | デンプン生成物の製造方法 |
| JPH08502888A (ja) * | 1992-10-30 | 1996-04-02 | エー、イー、ステーリー、マニュファクチュアリング、カンパニー | 脂肪が低下された食品の製造法 |
| WO1999009066A1 (en) * | 1997-08-14 | 1999-02-25 | 9068-3293 Quebec Inc. | Preparation of pregelatinized high amylose starch and debranched starch useful as an excipient for controlled release of active agents |
| JP2000517351A (ja) * | 1996-08-06 | 2000-12-26 | コオペラチイヴェ・ヴェルコオプ―エン・プロダクチイヴェレニギング―ヴァン―アアルダペルメエル・エン・デリヴァテン・アヴェベ・ビー．エイ． | プログラム遊離系のためのマトリックス形成剤としてのアミロース生成物、このアミロース生成物を調製するための方法、及びプログラム遊離系を作る方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3490742A (en) * | 1966-01-14 | 1970-01-20 | Staley Mfg Co A E | Compressed tablets |
| US3730840A (en) * | 1968-04-01 | 1973-05-01 | Hayashibara Co | Process for preparing low molecular weight amyloses |
| US3881991A (en) * | 1969-01-24 | 1975-05-06 | Hayashibara Co | Process for producing amylose powders having a mean degree of polymerization between 20{14 30 |
| US3622677A (en) * | 1969-07-07 | 1971-11-23 | Staley Mfg Co A E | Compressed tablets containing compacted starch as binder-disintegrant ingredient |
| US4072535A (en) * | 1970-12-28 | 1978-02-07 | A. E. Staley Manufacturing Company | Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules |
| US4384005A (en) * | 1980-09-26 | 1983-05-17 | General Foods Corporation | Non-friable, readily-soluble, compressed tablets and process for preparing same |
| US4551177A (en) * | 1984-04-23 | 1985-11-05 | National Starch And Chemical Corporation | Compressible starches as binders for tablets or capsules |
| US5089171A (en) * | 1988-10-14 | 1992-02-18 | National Starch And Chemical Investment Holding Corporation | Partially debranched starch clouds |
| US5194284A (en) * | 1988-10-14 | 1993-03-16 | National Starch And Chemical Investment Holding Corporation | Foods opacified with debranched starch |
| US4971723A (en) * | 1988-10-14 | 1990-11-20 | National Starch And Chemical Investment Holding Corporation | Partially debranched starches and enzymatic process for preparing the starches |
| US5468286A (en) * | 1989-10-25 | 1995-11-21 | National Starch And Chemical Investment Holding Corporation | Enzymatically debranched starches as tablet excipients |
| US5051271A (en) * | 1989-11-22 | 1991-09-24 | Opta Food Ingredients, Inc. | Starch-derived, food-grade, insoluble bulking agent |
| DE19911001C2 (de) * | 1999-03-12 | 2002-06-20 | Aventis Cropscience Gmbh | Verfahren zur Herstellung resistenter Stärke, resistente Stärke und deren Verwendung |
-
2002
- 2002-11-18 US US10/298,813 patent/US20030215499A1/en not_active Abandoned
-
2003
- 2003-05-13 EP EP03728856A patent/EP1503738A1/en not_active Withdrawn
- 2003-05-13 JP JP2004505016A patent/JP2005530777A/ja active Pending
- 2003-05-13 AU AU2003234416A patent/AU2003234416A1/en not_active Abandoned
- 2003-05-13 WO PCT/US2003/014944 patent/WO2003097017A1/en not_active Ceased
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0499648A1 (en) * | 1990-12-17 | 1992-08-26 | National Starch and Chemical Investment Holding Corporation | Enzymatically debranched starches as tablet excipients |
| JPH04230637A (ja) * | 1990-12-27 | 1992-08-19 | Natl Starch & Chem Investment Holding Corp | タブレット賦形剤としての酵素的に枝切りされたデンプン |
| JPH08500490A (ja) * | 1992-08-28 | 1996-01-23 | エー．イー．ステーリー、マニュファクチュアリング、カンパニー | 低脂肪食品の製造方法 |
| JPH08502888A (ja) * | 1992-10-30 | 1996-04-02 | エー、イー、ステーリー、マニュファクチュアリング、カンパニー | 脂肪が低下された食品の製造法 |
| JPH0856690A (ja) * | 1994-04-15 | 1996-03-05 | Cerestar Holding Bv | デンプン生成物の製造方法 |
| JP2000517351A (ja) * | 1996-08-06 | 2000-12-26 | コオペラチイヴェ・ヴェルコオプ―エン・プロダクチイヴェレニギング―ヴァン―アアルダペルメエル・エン・デリヴァテン・アヴェベ・ビー．エイ． | プログラム遊離系のためのマトリックス形成剤としてのアミロース生成物、このアミロース生成物を調製するための方法、及びプログラム遊離系を作る方法 |
| WO1999009066A1 (en) * | 1997-08-14 | 1999-02-25 | 9068-3293 Quebec Inc. | Preparation of pregelatinized high amylose starch and debranched starch useful as an excipient for controlled release of active agents |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008027904A (ja) * | 2006-06-26 | 2008-02-07 | Commissariat A L'energie Atomique | リチウム蓄電池電極用のデンプンならびにリチウムおよびチタン混合酸化物ベースを有する水性分散体 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1503738A1 (en) | 2005-02-09 |
| AU2003234416A1 (en) | 2003-12-02 |
| US20030215499A1 (en) | 2003-11-20 |
| WO2003097017A1 (en) | 2003-11-27 |
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