JP2005530736A5 - - Google Patents
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- Publication number
- JP2005530736A5 JP2005530736A5 JP2003585730A JP2003585730A JP2005530736A5 JP 2005530736 A5 JP2005530736 A5 JP 2005530736A5 JP 2003585730 A JP2003585730 A JP 2003585730A JP 2003585730 A JP2003585730 A JP 2003585730A JP 2005530736 A5 JP2005530736 A5 JP 2005530736A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- optionally substituted
- amount
- beta blocker
- esmolol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 *c1c2nc[n](C([C@@]3O)O[C@@](CO)[C@@]3O)c2ncn1 Chemical compound *c1c2nc[n](C([C@@]3O)O[C@@](CO)[C@@]3O)c2ncn1 0.000 description 3
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37376602P | 2002-04-18 | 2002-04-18 | |
| PCT/US2003/012043 WO2003088978A1 (en) | 2002-04-18 | 2003-04-18 | Method of treating arrhythmias comprising administration of an a1 adenosine agonist with a beta blocker, calcium channel blocker or a cardiac glycoside |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005530736A JP2005530736A (ja) | 2005-10-13 |
| JP2005530736A5 true JP2005530736A5 (https=) | 2006-06-01 |
Family
ID=29251078
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003585730A Pending JP2005530736A (ja) | 2002-04-18 | 2003-04-18 | ベーターブロッカー、カルシウムチャネルブロッカー、または心臓のグリコシドと共にａ１アデノシンアゴニストを投与することを含む不整脈の処置方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US7005425B2 (https=) |
| EP (1) | EP1494685B1 (https=) |
| JP (1) | JP2005530736A (https=) |
| KR (1) | KR20040106354A (https=) |
| CN (2) | CN101385738A (https=) |
| AT (1) | ATE418991T1 (https=) |
| AU (1) | AU2003235466C1 (https=) |
| CA (1) | CA2482928A1 (https=) |
| DE (1) | DE60325572D1 (https=) |
| ES (1) | ES2318129T3 (https=) |
| IL (1) | IL164652A0 (https=) |
| MX (1) | MXPA04010285A (https=) |
| NO (1) | NO20045005L (https=) |
| NZ (1) | NZ536001A (https=) |
| RU (1) | RU2332220C2 (https=) |
| WO (1) | WO2003088978A1 (https=) |
| ZA (1) | ZA200408411B (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1168912B1 (en) | 1999-03-23 | 2007-05-09 | Hibernation Therapeutics Limited | Organ arrest, protection and preservation |
| US6403567B1 (en) | 1999-06-22 | 2002-06-11 | Cv Therapeutics, Inc. | N-pyrazole A2A adenosine receptor agonists |
| USRE47351E1 (en) | 1999-06-22 | 2019-04-16 | Gilead Sciences, Inc. | 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists |
| CA2671940A1 (en) | 2000-02-23 | 2001-08-30 | Cv Therapeutics, Inc. | Identification of partial agonists of the a2a adenosine receptor |
| US7713946B2 (en) * | 2002-07-11 | 2010-05-11 | Cv Therapeutics, Inc. | Partial and full agonists A1 adenosine receptors |
| US7157440B2 (en) * | 2001-07-13 | 2007-01-02 | Cv Therapeutics, Inc. | Partial and full agonists of A1 adenosine receptors |
| CN101385738A (zh) * | 2002-04-18 | 2009-03-18 | Cv医药有限公司 | 包括给予A1腺苷激动剂以及β受体阻滞剂、钙通道阻滞剂、或强心苷的治疗心律失常的方法 |
| US8470801B2 (en) | 2002-07-29 | 2013-06-25 | Gilead Sciences, Inc. | Myocardial perfusion imaging methods and compositions |
| GB2436255B (en) * | 2002-12-23 | 2007-11-28 | Global Cardiac Solutions Pty L | Organ preconditioning, arrest, protection, preservation and recovery |
| CA2573682A1 (en) * | 2004-07-12 | 2006-02-16 | Cv Therapeutics, Inc. | Process for the preparation of a1 adenosine receptor agonists |
| US20060019954A1 (en) * | 2004-07-20 | 2006-01-26 | Cedars-Sinai Medical Center | Method for reducing the likelihood of the occurrence of cardiac arrhythmias |
| US7300923B2 (en) * | 2004-08-30 | 2007-11-27 | Cv Therapeutics, Inc. | Partial and full agonists of A1 adenosine receptors |
| CA2581086C (en) | 2004-09-14 | 2023-11-07 | The Regents Of The University Of Colorado, A Body Corporate | Method for treatment with bucindolol based on genetic targeting |
| US7822474B2 (en) * | 2005-11-30 | 2010-10-26 | Cedars-Sinai Medical Center | Methods for the prediction of arrhythmias and prevention of sudden cardiac death |
| US7732595B2 (en) | 2006-02-03 | 2010-06-08 | Gilead Palo Alto, Inc. | Process for preparing an A2A-adenosine receptor agonist and its polymorphs |
| JP2009538834A (ja) | 2006-05-29 | 2009-11-12 | ハイバーネイション セラピューティクス リミテッド | 組織維持の改善 |
| ES2539762T3 (es) | 2006-07-25 | 2015-07-03 | Hibernation Therapeutics, A Kf Llc | Tratamiento de traumatismos |
| WO2008106724A1 (en) | 2007-03-02 | 2008-09-12 | Hibernation Therapeutics Limited | Transplants |
| US20100311738A1 (en) | 2007-12-21 | 2010-12-09 | Aop Orphan Pharmaceuticals Ag | Pharmaceutical Composition For The Parenteral Administration Of Ultrashort-Effective Beta-Adrenoreceptor Antagonists |
| AU2009296235A1 (en) * | 2008-09-29 | 2010-04-01 | Gilead Sciences, Inc. | Combinations of a rate control agent and an A-2-alpha receptor antagonist for use in multidetector computed tomography methods |
| GB0903299D0 (en) * | 2009-02-26 | 2009-04-08 | Guys And St Thomas Nhs Foundat | Composition and methods |
| EP3552602B1 (en) * | 2009-03-18 | 2025-03-05 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| WO2011019752A2 (en) | 2009-08-14 | 2011-02-17 | Gilead Palo Alto, Inc. | A1 adenosine receptor agonist polymorphs |
| SG182285A1 (en) | 2010-01-11 | 2012-08-30 | Inotek Pharmaceuticals Corp | Combination, kit and method of reducing intraocular pressure |
| ES2613255T3 (es) * | 2010-03-19 | 2017-05-23 | Inotek Pharmaceuticals Corporation | Composiciones combinadas de agonistas de adenosina A1 y bloqueadores de receptores ß-adrenérgicos no selectivos para reducir la presión intraocular |
| EA201290958A1 (ru) | 2010-03-26 | 2013-04-30 | Инотек Фармасьютикалз Корпорейшн | Способ снижения внутриглазного давления у людей с применением n6-циклопентиладенозина (cpa), производных cpa или их пролекарств |
| US20120005128A1 (en) * | 2010-06-29 | 2012-01-05 | Sanofi | Methods for reducing the risk of an adverse dronedarone / calcium channel blockers interaction in a patient suffering from atrial fibrilation |
| BR112014018413A8 (pt) | 2012-01-26 | 2017-07-11 | Inotek Pharmaceuticals Corp | Polimorfos anidros de nitrato de metila [(2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-diidroxitetraidrofuran-2-il)] e processos de preparação do mesmo |
| CA2903114A1 (en) | 2013-03-15 | 2014-09-25 | Inotek Pharmaceuticals Corporation | Ophthalmic formulations |
| WO2015006831A1 (en) | 2013-07-17 | 2015-01-22 | Hts Therapeutics Pty Ltd | A method for reducing, inflammation, coagulation and adhesions |
| WO2015089494A1 (en) * | 2013-12-13 | 2015-06-18 | Ankenman Ralph | Compositions and methods for treating dysregulated systems |
| CN109069495A (zh) | 2016-02-01 | 2018-12-21 | 英凯达治疗公司 | 电子监测联合吸入药理学疗法管理包括心房颤动在内的心律失常 |
| CN106370754B (zh) * | 2016-11-07 | 2019-03-08 | 西安科技大学 | 基于手性高效液相色谱-质谱/质谱技术定量检测布新洛尔光学异构体含量的方法 |
| AU2018266199A1 (en) | 2017-05-10 | 2019-11-07 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| US10744087B2 (en) | 2018-03-22 | 2020-08-18 | Incarda Therapeutics, Inc. | Method to slow ventricular rate |
| US10799138B2 (en) | 2018-04-05 | 2020-10-13 | University Of Maryland, Baltimore | Method of administering sotalol IV/switch |
| US10512620B1 (en) | 2018-08-14 | 2019-12-24 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US11610660B1 (en) | 2021-08-20 | 2023-03-21 | AltaThera Pharmaceuticals LLC | Antiarrhythmic drug dosing methods, medical devices, and systems |
| US12396970B2 (en) | 2021-08-20 | 2025-08-26 | AltaThera Pharmaceuticals LLC | Anti-arrhythmic compositions and methods |
| US11344518B2 (en) | 2018-08-14 | 2022-05-31 | AltaThera Pharmaceuticals LLC | Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame |
| US11696902B2 (en) | 2018-08-14 | 2023-07-11 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| JP7156154B2 (ja) * | 2019-04-18 | 2022-10-19 | 株式会社島津製作所 | 培地処理システム及び培地処理方法 |
| AU2020323594B2 (en) | 2019-08-01 | 2022-02-03 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
| US11007185B2 (en) | 2019-08-01 | 2021-05-18 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5108363A (en) * | 1988-02-19 | 1992-04-28 | Gensia Pharmaceuticals, Inc. | Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist |
| US5736528A (en) * | 1993-10-28 | 1998-04-07 | University Of Florida Research Foundation, Inc. | N6 -(epoxynorborn-2-yl) adenosines as A1 adenosine receptor agonists |
| AU722110B2 (en) * | 1996-06-28 | 2000-07-20 | Merck & Co., Inc. | Pharmaceutical preparation |
| US5789416B1 (en) * | 1996-08-27 | 1999-10-05 | Cv Therapeutics Inc | N6 mono heterocyclic substituted adenosine derivatives |
| JP2001509808A (ja) * | 1997-01-31 | 2001-07-24 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 多機能性カルシウム／カルモジュリン−依存性プロテインキナーゼの阻害による不整脈の処置 |
| CO5180581A1 (es) * | 1999-09-30 | 2002-07-30 | Pfizer Prod Inc | Compuestos para el tratamiento de la isquemia ciones farmaceuticas que los contienen para el tratamiento de la isquemia |
| WO2001040799A2 (en) | 1999-12-03 | 2001-06-07 | Cv Therapeutics, Inc. | Method of identifying partial adenosine a1 receptor agonists and their use in the treatment of arrhythmias |
| US6605597B1 (en) * | 1999-12-03 | 2003-08-12 | Cv Therapeutics, Inc. | Partial or full A1agonists-N-6 heterocyclic 5′-thio substituted adenosine derivatives |
| AU9259101A (en) * | 2000-09-08 | 2002-03-22 | Cv Therapeutics Inc | Purine ribosides as antiarrhythmics |
| US6946449B2 (en) | 2001-07-13 | 2005-09-20 | Cv Therapeutics, Inc. | Partial and full agonists of A1 adenosine receptors |
| CN101385738A (zh) * | 2002-04-18 | 2009-03-18 | Cv医药有限公司 | 包括给予A1腺苷激动剂以及β受体阻滞剂、钙通道阻滞剂、或强心苷的治疗心律失常的方法 |
-
2003
- 2003-04-18 CN CNA2008101711378A patent/CN101385738A/zh active Pending
- 2003-04-18 ES ES03724098T patent/ES2318129T3/es not_active Expired - Lifetime
- 2003-04-18 RU RU2004130826/14A patent/RU2332220C2/ru not_active IP Right Cessation
- 2003-04-18 CN CNA038086999A patent/CN1646142A/zh active Pending
- 2003-04-18 NZ NZ536001A patent/NZ536001A/en not_active IP Right Cessation
- 2003-04-18 WO PCT/US2003/012043 patent/WO2003088978A1/en not_active Ceased
- 2003-04-18 KR KR10-2004-7016764A patent/KR20040106354A/ko not_active Abandoned
- 2003-04-18 DE DE60325572T patent/DE60325572D1/de not_active Expired - Lifetime
- 2003-04-18 US US10/418,654 patent/US7005425B2/en not_active Expired - Fee Related
- 2003-04-18 MX MXPA04010285A patent/MXPA04010285A/es active IP Right Grant
- 2003-04-18 AT AT03724098T patent/ATE418991T1/de not_active IP Right Cessation
- 2003-04-18 EP EP03724098A patent/EP1494685B1/en not_active Expired - Lifetime
- 2003-04-18 CA CA002482928A patent/CA2482928A1/en not_active Abandoned
- 2003-04-18 JP JP2003585730A patent/JP2005530736A/ja active Pending
- 2003-04-18 AU AU2003235466A patent/AU2003235466C1/en not_active Ceased
-
2004
- 2004-10-18 ZA ZA200408411A patent/ZA200408411B/en unknown
- 2004-10-18 IL IL16465204A patent/IL164652A0/xx unknown
- 2004-11-17 NO NO20045005A patent/NO20045005L/no not_active Application Discontinuation
-
2005
- 2005-10-28 US US11/262,025 patent/US7479485B2/en not_active Expired - Fee Related
-
2009
- 2009-01-09 US US12/351,731 patent/US20090118221A1/en not_active Abandoned
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