JP2005529079A - 細胞増殖性疾患を処置する化合物および方法 - Google Patents

細胞増殖性疾患を処置する化合物および方法 Download PDF

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Publication number
JP2005529079A
JP2005529079A JP2003572976A JP2003572976A JP2005529079A JP 2005529079 A JP2005529079 A JP 2005529079A JP 2003572976 A JP2003572976 A JP 2003572976A JP 2003572976 A JP2003572976 A JP 2003572976A JP 2005529079 A JP2005529079 A JP 2005529079A
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Japan
Prior art keywords
pyran
group
pentyloxy
tetrahydro
indol
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Pending
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JP2003572976A
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English (en)
Japanese (ja)
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JP2005529079A5 (enExample
Inventor
ルブラン，ベロニク
ルブロン，ベルトラン
メル−ミロヴァノビッチ，ドミニク
ロペス・ロドリゲス，マリア・ルース
ヴィソ・ベロンダ，アルマ
ボウソレイユ，エリク
ピカール，ヴィルジニー
ピナール・ピネド，マリア・デル・カルメン
タヴェルネ，ティエリー
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ExonHit Therapeutics SA
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ExonHit Therapeutics SA
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Publication date
Application filed by ExonHit Therapeutics SA filed Critical ExonHit Therapeutics SA
Publication of JP2005529079A publication Critical patent/JP2005529079A/ja
Publication of JP2005529079A5 publication Critical patent/JP2005529079A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
JP2003572976A 2002-03-01 2003-02-28 細胞増殖性疾患を処置する化合物および方法 Pending JP2005529079A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/085,141 US6552073B1 (en) 2002-03-01 2002-03-01 Compounds and methods of treating cell proliferative diseases
PCT/IB2003/001050 WO2003074508A1 (en) 2002-03-01 2003-02-28 Compounds and methods of treating cell proliferative diseases

Publications (2)

Publication Number Publication Date
JP2005529079A true JP2005529079A (ja) 2005-09-29
JP2005529079A5 JP2005529079A5 (enExample) 2006-04-06

Family

ID=22189708

Family Applications (1)

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JP2003572976A Pending JP2005529079A (ja) 2002-03-01 2003-02-28 細胞増殖性疾患を処置する化合物および方法

Country Status (6)

Country Link
US (2) US6552073B1 (enExample)
EP (1) EP1480966A1 (enExample)
JP (1) JP2005529079A (enExample)
AU (1) AU2003209924A1 (enExample)
CA (1) CA2477003A1 (enExample)
WO (1) WO2003074508A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006519221A (ja) * 2003-02-28 2006-08-24 エグゾニ・テラピューティック・ソシエテ・アノニム 化合物並びに細胞増殖性疾患、網膜症及び関節炎を処置する方法
JP2019524797A (ja) * 2016-08-23 2019-09-05 ニューリム・ファーマシューティカルズ・リミテッドＮｅｕｒｉｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ． 掻痒症および／または痒みの治療方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6552073B1 (en) * 2002-03-01 2003-04-22 Exonhit Therapeutics Sa Compounds and methods of treating cell proliferative diseases
WO2005110399A2 (en) * 2004-04-29 2005-11-24 The Regents Of The University Of California Zinc-binding groups for metalloprotein inhibitors
EP1755586A2 (en) * 2004-04-29 2007-02-28 The Regents of the University of California Hydroxypyridinone, hydroxypyridinethione, pyrone, and thiopyrone metalloprotein inhibitors
DE102007002260A1 (de) 2007-01-16 2008-07-31 Sanofi-Aventis Verwendung von substituierten Pyranonsäurederivaten zur Herstellung von Medikamenten zur Behandlung des Metabolischen Syndroms

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644071A (en) * 1984-07-11 1987-02-17 G. D. Searle & Co. Aralkoxy and aryloxyalkoxy kojic acid derivatives
US4705871A (en) * 1984-07-11 1987-11-10 G. D. Searle & Co. Aralkoxy and aryloxyalkoxy kojic acid derivatives
US4812584A (en) * 1984-07-11 1989-03-14 G. D. Searle & Co. Aralkoxy and aryloxyalkoxy kojic acid derivatives
PH22520A (en) * 1984-11-12 1988-10-17 Yamanouchi Pharma Co Ltd Heterocyclic compounds having 4-lover alkyl-3-hydroxy-2-lower alkyl phenoxy-lower alkylene-y-group, and process of producing them
US6552073B1 (en) * 2002-03-01 2003-04-22 Exonhit Therapeutics Sa Compounds and methods of treating cell proliferative diseases

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006519221A (ja) * 2003-02-28 2006-08-24 エグゾニ・テラピューティック・ソシエテ・アノニム 化合物並びに細胞増殖性疾患、網膜症及び関節炎を処置する方法
JP2019524797A (ja) * 2016-08-23 2019-09-05 ニューリム・ファーマシューティカルズ・リミテッドＮｅｕｒｉｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ． 掻痒症および／または痒みの治療方法

Also Published As

Publication number Publication date
US20050054629A1 (en) 2005-03-10
AU2003209924A1 (en) 2003-09-16
CA2477003A1 (en) 2003-09-12
US6552073B1 (en) 2003-04-22
WO2003074508A1 (en) 2003-09-12
WO2003074508B1 (en) 2003-11-27
EP1480966A1 (en) 2004-12-01

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