JP2005528319A5 - - Google Patents
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- Publication number
- JP2005528319A5 JP2005528319A5 JP2003512448A JP2003512448A JP2005528319A5 JP 2005528319 A5 JP2005528319 A5 JP 2005528319A5 JP 2003512448 A JP2003512448 A JP 2003512448A JP 2003512448 A JP2003512448 A JP 2003512448A JP 2005528319 A5 JP2005528319 A5 JP 2005528319A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- transduced
- rrz2
- lnl6
- marking
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30428301P | 2001-07-10 | 2001-07-10 | |
| US30412701P | 2001-07-10 | 2001-07-10 | |
| US60/304,127 | 2001-07-10 | ||
| US60/304,283 | 2001-07-10 | ||
| US34348401P | 2001-12-21 | 2001-12-21 | |
| US60/343,484 | 2001-12-21 | ||
| US38606302P | 2002-06-04 | 2002-06-04 | |
| US60/386,063 | 2002-06-04 | ||
| PCT/US2002/021907 WO2003006691A1 (en) | 2001-07-10 | 2002-07-10 | Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009211662A Division JP2010077125A (ja) | 2001-07-10 | 2009-09-14 | 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005528319A JP2005528319A (ja) | 2005-09-22 |
| JP2005528319A5 true JP2005528319A5 (https=) | 2012-09-27 |
| JP5179697B2 JP5179697B2 (ja) | 2013-04-10 |
Family
ID=27501852
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003512448A Expired - Fee Related JP5179697B2 (ja) | 2001-07-10 | 2002-07-10 | 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用 |
| JP2009211662A Pending JP2010077125A (ja) | 2001-07-10 | 2009-09-14 | 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009211662A Pending JP2010077125A (ja) | 2001-07-10 | 2009-09-14 | 造血前駆細胞を遺伝的に改変する方法及び改変された細胞の使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US7345025B2 (https=) |
| EP (2) | EP2322618A1 (https=) |
| JP (2) | JP5179697B2 (https=) |
| KR (1) | KR101015913B1 (https=) |
| CN (2) | CN101926824A (https=) |
| AT (1) | ATE490322T1 (https=) |
| AU (1) | AU2002316640C1 (https=) |
| BR (1) | BR0211079A (https=) |
| CA (1) | CA2453531A1 (https=) |
| DE (1) | DE60238486D1 (https=) |
| DK (1) | DK1414996T3 (https=) |
| IL (2) | IL159637A0 (https=) |
| MX (1) | MXPA04000268A (https=) |
| NZ (1) | NZ530624A (https=) |
| WO (1) | WO2003006691A1 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020058636A1 (en) * | 1994-09-21 | 2002-05-16 | Geoffrey P. Symonds | Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
| CA2279673A1 (en) * | 1995-12-15 | 1997-06-16 | Enzo Therapeutics, Inc. | Property effecting and/or property exhibiting constructs for the expression of non-native nucleic acids for therapeutic and diagnostic uses |
| US6627442B1 (en) * | 2000-08-31 | 2003-09-30 | Virxsys Corporation | Methods for stable transduction of cells with hiv-derived viral vectors |
| ES2358187T3 (es) | 2001-07-10 | 2011-05-06 | JOHNSON & JOHNSON RESEARCH PTY LIMITED | Procedimientos para la modificación genética de las células progenitoras hematopoyéticas y utilizaciones de las células modificadas. |
| US7345025B2 (en) | 2001-07-10 | 2008-03-18 | Johnson & Johnson Research Pty. Limited | Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells |
| CA2453187A1 (en) * | 2001-07-10 | 2003-01-23 | J & J Research Pty Ltd | Production of transduced hematopoietic progenitor cells |
| AU2002326906C1 (en) | 2001-09-13 | 2009-01-29 | California Institute Of Technology | Method for expression of small antiviral RNA molecules within a cell |
| US7737124B2 (en) * | 2001-09-13 | 2010-06-15 | California Institute Of Technology | Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell |
| DE10212892A1 (de) * | 2002-03-20 | 2003-10-09 | Basf Plant Science Gmbh | Konstrukte und Verfahren zur Regulation der Genexpression |
| DE10224750A1 (de) | 2002-06-04 | 2003-12-24 | Fresenius Medical Care De Gmbh | Vorrichtung zur Behandlung einer medizinischen Flüssigkeit |
| WO2004071418A2 (en) * | 2003-02-06 | 2004-08-26 | Walter Reed Army Institute Of Research | Compounds for the treatment of systemic lupus erythematosus |
| AU2004227205B2 (en) * | 2003-04-08 | 2010-06-10 | Yeda Research And Development Co. Ltd | Stem cells having increased sensitivity to a chemoattractant and methods of generating and using same |
| GB0410130D0 (en) * | 2004-05-06 | 2004-06-09 | Molmed Spa | Cell preparation |
| US7935074B2 (en) * | 2005-02-28 | 2011-05-03 | Fresenius Medical Care Holdings, Inc. | Cassette system for peritoneal dialysis machine |
| US8197231B2 (en) | 2005-07-13 | 2012-06-12 | Purity Solutions Llc | Diaphragm pump and related methods |
| JP4268209B2 (ja) * | 2005-07-20 | 2009-05-27 | ソウル ナショナル ユニバーシティ インダストリー ファウンデーション | 子宮内膜細胞を用いた造血幹細胞または前駆細胞の培養及び増殖方法 |
| EP2032691A2 (en) * | 2006-06-15 | 2009-03-11 | Neostem, Inc | Processing procedure for peripheral blood stem cells |
| JP2011160661A (ja) * | 2008-06-02 | 2011-08-25 | Kyowa Hakko Kirin Co Ltd | 血球細胞の初期化法 |
| US8112365B2 (en) * | 2008-12-19 | 2012-02-07 | Foster Scott C | System and method for online employment recruiting and evaluation |
| US20100210989A1 (en) | 2008-12-23 | 2010-08-19 | Janet Lesley Macpherson | Processing blood |
| US8192401B2 (en) * | 2009-03-20 | 2012-06-05 | Fresenius Medical Care Holdings, Inc. | Medical fluid pump systems and related components and methods |
| US20120034197A1 (en) * | 2009-04-09 | 2012-02-09 | Stemcyte Inc. | Hiv-resistant stem cells and uses thereof |
| CN102497895A (zh) | 2009-07-15 | 2012-06-13 | 弗雷塞尼斯医疗保健控股公司 | 医疗流体盒及相关系统和方法 |
| US8720913B2 (en) | 2009-08-11 | 2014-05-13 | Fresenius Medical Care Holdings, Inc. | Portable peritoneal dialysis carts and related systems |
| JP5946775B2 (ja) * | 2010-12-01 | 2016-07-06 | 日産化学工業株式会社 | ピラゾール化合物による造血幹細胞の製造方法 |
| DE102010053973A1 (de) | 2010-12-09 | 2012-06-14 | Fresenius Medical Care Deutschland Gmbh | Medizinisches Gerät mit einer Heizung |
| EP2654825B1 (en) | 2010-12-20 | 2017-08-02 | Fresenius Medical Care Holdings, Inc. | Medical fluid cassettes and related systems and methods |
| US9624915B2 (en) | 2011-03-09 | 2017-04-18 | Fresenius Medical Care Holdings, Inc. | Medical fluid delivery sets and related systems and methods |
| CN103648540B (zh) | 2011-04-21 | 2016-06-01 | 弗雷塞尼斯医疗保健控股公司 | 医疗流体泵送系统及相关装置和方法 |
| US9186449B2 (en) | 2011-11-01 | 2015-11-17 | Fresenius Medical Care Holdings, Inc. | Dialysis machine support assemblies and related systems and methods |
| US9610392B2 (en) | 2012-06-08 | 2017-04-04 | Fresenius Medical Care Holdings, Inc. | Medical fluid cassettes and related systems and methods |
| US9500188B2 (en) | 2012-06-11 | 2016-11-22 | Fresenius Medical Care Holdings, Inc. | Medical fluid cassettes and related systems and methods |
| IN2015DN02032A (https=) * | 2012-09-07 | 2015-08-14 | Univ Yale | |
| CA2887706C (en) * | 2012-11-05 | 2022-08-02 | Regeneron Pharmaceuticals | Genetically modified non-human animals and methods of use thereof |
| CN105102612B (zh) * | 2012-12-06 | 2020-11-17 | 恩立夫克治疗有限责任公司 | 治疗性凋亡细胞制剂、其制备方法以及其用途 |
| US9561323B2 (en) | 2013-03-14 | 2017-02-07 | Fresenius Medical Care Holdings, Inc. | Medical fluid cassette leak detection methods and devices |
| US10117985B2 (en) | 2013-08-21 | 2018-11-06 | Fresenius Medical Care Holdings, Inc. | Determining a volume of medical fluid pumped into or out of a medical fluid cassette |
| CN103471896A (zh) * | 2013-09-09 | 2013-12-25 | 上海兰卫临床检验有限公司 | 革兰染色液质控品制备方法 |
| US20200199534A1 (en) * | 2017-04-27 | 2020-06-25 | Fred Hutchinson Cancer Research Center | Therapeutic formulations containing cd34+ stem cells derived from negative selection |
| MX2020004811A (es) * | 2017-11-15 | 2020-10-07 | Weird Science Llc | Métodos y composiciones de reconstrucción no mieloablativa de médula ósea. |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE115999T1 (de) | 1987-12-15 | 1995-01-15 | Gene Shears Pty Ltd | Ribozyme. |
| US5254678A (en) | 1987-12-15 | 1993-10-19 | Gene Shears Pty. Limited | Ribozymes |
| US5866701A (en) | 1988-09-20 | 1999-02-02 | The Board Of Regents For Northern Illinois University Of Dekalb | HIV targeted hairpin ribozymes |
| US4978514A (en) | 1989-09-12 | 1990-12-18 | Fuel Tech, Inc. | Combined catalytic/non-catalytic process for nitrogen oxides reduction |
| US5225337A (en) | 1989-09-25 | 1993-07-06 | Innovir Laboratories, Inc. | Ribozyme compositions and methods for use |
| US5500357A (en) * | 1990-11-02 | 1996-03-19 | Agency Of Industrial Science & Technology, Ministry Of International Trade & Industry | RNA transcription system using novel ribozyme |
| WO1992017211A1 (en) | 1991-04-05 | 1992-10-15 | Edison Animal Biotechnology Center, Ohio University | Retrovirus inhibition with antisense nucleic acids complementary to packaging sequences |
| US5525468A (en) * | 1992-05-14 | 1996-06-11 | Ribozyme Pharmaceuticals, Inc. | Assay for Ribozyme target site |
| US5693535A (en) * | 1992-05-14 | 1997-12-02 | Ribozyme Pharmaceuticals, Inc. | HIV targeted ribozymes |
| US5911983A (en) | 1992-06-26 | 1999-06-15 | University Of Pittsburgh | Gene therapy for Gaucher disease using retroviral vectors |
| PT652705E (pt) | 1992-06-29 | 2006-05-31 | Gene Shears Pty Ltd | Acidos nucleicos e metodos para a sua utilizacao para combater patogenios virais |
| EP0681482B1 (en) | 1993-01-22 | 2005-12-07 | University Research Corporation | Localization of therapeutic agents |
| IL108719A0 (en) | 1993-02-25 | 1994-08-26 | Ortho Pharma Corp | Expression constructs containing hiv inhibitory antisense and other nucleotide sequences, retroviralvectors and recombinant retroviruses containing them |
| WO1995004818A1 (en) | 1993-08-06 | 1995-02-16 | Ribozyme Pharmaceuticals, Inc. | Method and reagent for inhibiting human immunodeficiency virus replication |
| US5624803A (en) * | 1993-10-14 | 1997-04-29 | The Regents Of The University Of California | In vivo oligonucleotide generator, and methods of testing the binding affinity of triplex forming oligonucleotides derived therefrom |
| US5712384A (en) * | 1994-01-05 | 1998-01-27 | Gene Shears Pty Ltd. | Ribozymes targeting retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
| CA2180358A1 (en) | 1994-01-05 | 1995-07-13 | Geoffrey P. Symonds | Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
| US20020058636A1 (en) | 1994-09-21 | 2002-05-16 | Geoffrey P. Symonds | Ribozymes targeting the retroviral packaging sequence expression constructs and recombinant retroviruses containing such constructs |
| AU5557196A (en) | 1995-04-20 | 1996-11-07 | Chiron Corporation | High efficiency ex vivo transduction of hematopoietic stem cells by recombinant retroviral preparations |
| US5741706A (en) | 1996-06-13 | 1998-04-21 | Immusol, Incorporated | Anti-HIV ribozymes |
| TWI239352B (en) * | 1997-07-23 | 2005-09-11 | Takara Bio Inc | Gene transfer method with the use of serum-free medium |
| US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| US6060317A (en) * | 1998-08-11 | 2000-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Method of transducing mammalian cells, and products related thereto |
| AU2036700A (en) | 1998-12-04 | 2000-06-26 | City Of Hope | A method of genetically modifying very primitive quiescent human hematopoietic stem cells |
| WO2000075291A2 (en) * | 1999-06-08 | 2000-12-14 | Novartis Ag | Cells with enforced expression of bcl-xl |
| WO2002022611A2 (en) | 2000-09-13 | 2002-03-21 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| JP2004532616A (ja) | 2000-12-28 | 2004-10-28 | ジョンソン・アンド・ジョンソン・リサーチ・ピー・ティー・ワイ・リミテッド | 二本鎖rna仲介遺伝子抑制 |
| CA2453187A1 (en) * | 2001-07-10 | 2003-01-23 | J & J Research Pty Ltd | Production of transduced hematopoietic progenitor cells |
| ES2358187T3 (es) | 2001-07-10 | 2011-05-06 | JOHNSON & JOHNSON RESEARCH PTY LIMITED | Procedimientos para la modificación genética de las células progenitoras hematopoyéticas y utilizaciones de las células modificadas. |
| US7345025B2 (en) | 2001-07-10 | 2008-03-18 | Johnson & Johnson Research Pty. Limited | Methods for genetic modification of hematopoietic progenitor cells and uses of the modified cells |
| KR100646702B1 (ko) * | 2001-08-16 | 2006-11-17 | 에스케이씨 주식회사 | 홀 및/또는 그루브로 형성된 화학적 기계적 연마패드 |
-
2002
- 2002-07-10 US US10/192,980 patent/US7345025B2/en not_active Expired - Fee Related
- 2002-07-10 AU AU2002316640A patent/AU2002316640C1/en not_active Ceased
- 2002-07-10 EP EP10183035A patent/EP2322618A1/en not_active Withdrawn
- 2002-07-10 DK DK02746963.4T patent/DK1414996T3/da active
- 2002-07-10 CA CA002453531A patent/CA2453531A1/en not_active Abandoned
- 2002-07-10 AT AT02746963T patent/ATE490322T1/de not_active IP Right Cessation
- 2002-07-10 MX MXPA04000268A patent/MXPA04000268A/es active IP Right Grant
- 2002-07-10 JP JP2003512448A patent/JP5179697B2/ja not_active Expired - Fee Related
- 2002-07-10 DE DE60238486T patent/DE60238486D1/de not_active Expired - Lifetime
- 2002-07-10 NZ NZ530624A patent/NZ530624A/en not_active IP Right Cessation
- 2002-07-10 IL IL15963702A patent/IL159637A0/xx unknown
- 2002-07-10 CN CN2010102736257A patent/CN101926824A/zh active Pending
- 2002-07-10 EP EP02746963A patent/EP1414996B1/en not_active Expired - Lifetime
- 2002-07-10 KR KR1020047000421A patent/KR101015913B1/ko not_active Expired - Fee Related
- 2002-07-10 WO PCT/US2002/021907 patent/WO2003006691A1/en not_active Ceased
- 2002-07-10 BR BR0211079-2A patent/BR0211079A/pt not_active IP Right Cessation
- 2002-07-10 CN CNA028177428A patent/CN1553963A/zh active Pending
-
2003
- 2003-12-29 IL IL159637A patent/IL159637A/en not_active IP Right Cessation
-
2006
- 2006-08-18 US US11/506,722 patent/US7776595B2/en not_active Expired - Fee Related
-
2009
- 2009-09-14 JP JP2009211662A patent/JP2010077125A/ja active Pending
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