JP2005527581A5 - - Google Patents
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- Publication number
- JP2005527581A5 JP2005527581A5 JP2003583342A JP2003583342A JP2005527581A5 JP 2005527581 A5 JP2005527581 A5 JP 2005527581A5 JP 2003583342 A JP2003583342 A JP 2003583342A JP 2003583342 A JP2003583342 A JP 2003583342A JP 2005527581 A5 JP2005527581 A5 JP 2005527581A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- subject
- inflammation
- inflammatory response
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 77
- 206010061218 Inflammation Diseases 0.000 claims 20
- 230000004054 inflammatory process Effects 0.000 claims 19
- 230000028709 inflammatory response Effects 0.000 claims 18
- 102000004169 proteins and genes Human genes 0.000 claims 14
- 108090000623 proteins and genes Proteins 0.000 claims 14
- 230000005779 cell damage Effects 0.000 claims 13
- 208000037887 cell injury Diseases 0.000 claims 13
- 230000000451 tissue damage Effects 0.000 claims 13
- 210000004988 splenocyte Anatomy 0.000 claims 10
- 210000001519 tissue Anatomy 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 8
- 231100000827 tissue damage Toxicity 0.000 claims 8
- 230000004069 differentiation Effects 0.000 claims 6
- 239000002552 dosage form Substances 0.000 claims 6
- 208000026278 immune system disease Diseases 0.000 claims 5
- 210000004698 lymphocyte Anatomy 0.000 claims 5
- 230000001404 mediated effect Effects 0.000 claims 5
- 230000006907 apoptotic process Effects 0.000 claims 4
- 230000003013 cytotoxicity Effects 0.000 claims 4
- 231100000135 cytotoxicity Toxicity 0.000 claims 4
- 230000002401 inhibitory effect Effects 0.000 claims 4
- 210000000056 organ Anatomy 0.000 claims 4
- 230000035755 proliferation Effects 0.000 claims 4
- 210000004989 spleen cell Anatomy 0.000 claims 4
- 230000004083 survival effect Effects 0.000 claims 4
- 230000001154 acute effect Effects 0.000 claims 3
- 230000016784 immunoglobulin production Effects 0.000 claims 3
- 230000005764 inhibitory process Effects 0.000 claims 3
- 210000000822 natural killer cell Anatomy 0.000 claims 3
- 230000004936 stimulating effect Effects 0.000 claims 3
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 201000004624 Dermatitis Diseases 0.000 claims 2
- 201000011152 Pemphigus Diseases 0.000 claims 2
- 206010041660 Splenomegaly Diseases 0.000 claims 2
- 230000010398 acute inflammatory response Effects 0.000 claims 2
- 210000003423 ankle Anatomy 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 230000001363 autoimmune Effects 0.000 claims 2
- 201000003710 autoimmune thrombocytopenic purpura Diseases 0.000 claims 2
- 230000005784 autoimmunity Effects 0.000 claims 2
- 230000001684 chronic effect Effects 0.000 claims 2
- 230000012085 chronic inflammatory response Effects 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 238000002513 implantation Methods 0.000 claims 2
- 210000003734 kidney Anatomy 0.000 claims 2
- 210000003127 knee Anatomy 0.000 claims 2
- 210000004185 liver Anatomy 0.000 claims 2
- 201000001976 pemphigus vulgaris Diseases 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 210000003491 skin Anatomy 0.000 claims 2
- 210000000952 spleen Anatomy 0.000 claims 2
- 208000011580 syndromic disease Diseases 0.000 claims 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 2
- 210000001541 thymus gland Anatomy 0.000 claims 2
- 210000000707 wrist Anatomy 0.000 claims 2
- 208000026872 Addison Disease Diseases 0.000 claims 1
- 201000004384 Alopecia Diseases 0.000 claims 1
- 208000003343 Antiphospholipid Syndrome Diseases 0.000 claims 1
- 208000032467 Aplastic anaemia Diseases 0.000 claims 1
- 208000032116 Autoimmune Experimental Encephalomyelitis Diseases 0.000 claims 1
- 208000023328 Basedow disease Diseases 0.000 claims 1
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 claims 1
- 208000033222 Biliary cirrhosis primary Diseases 0.000 claims 1
- 208000014644 Brain disease Diseases 0.000 claims 1
- 241000282693 Cercopithecidae Species 0.000 claims 1
- 208000002691 Choroiditis Diseases 0.000 claims 1
- 206010008909 Chronic Hepatitis Diseases 0.000 claims 1
- 208000015943 Coeliac disease Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010010741 Conjunctivitis Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010011891 Deafness neurosensory Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 208000032274 Encephalopathy Diseases 0.000 claims 1
- 206010016717 Fistula Diseases 0.000 claims 1
- 208000024869 Goodpasture syndrome Diseases 0.000 claims 1
- 206010072579 Granulomatosis with polyangiitis Diseases 0.000 claims 1
- 208000015023 Graves' disease Diseases 0.000 claims 1
- 208000030836 Hashimoto thyroiditis Diseases 0.000 claims 1
- 206010019233 Headaches Diseases 0.000 claims 1
- 208000035186 Hemolytic Autoimmune Anemia Diseases 0.000 claims 1
- 206010019755 Hepatitis chronic active Diseases 0.000 claims 1
- 208000007514 Herpes zoster Diseases 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 206010021245 Idiopathic thrombocytopenic purpura Diseases 0.000 claims 1
- 206010022491 Insulin resistant diabetes Diseases 0.000 claims 1
- 208000029523 Interstitial Lung disease Diseases 0.000 claims 1
- 206010023230 Joint stiffness Diseases 0.000 claims 1
- 208000003456 Juvenile Arthritis Diseases 0.000 claims 1
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 claims 1
- 206010028813 Nausea Diseases 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 208000031845 Pernicious anaemia Diseases 0.000 claims 1
- 206010065159 Polychondritis Diseases 0.000 claims 1
- 208000003971 Posterior uveitis Diseases 0.000 claims 1
- 208000012654 Primary biliary cholangitis Diseases 0.000 claims 1
- 206010036774 Proctitis Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 206010037660 Pyrexia Diseases 0.000 claims 1
- 206010039710 Scleroderma Diseases 0.000 claims 1
- 208000009966 Sensorineural Hearing Loss Diseases 0.000 claims 1
- 208000021386 Sjogren Syndrome Diseases 0.000 claims 1
- 206010042033 Stevens-Johnson syndrome Diseases 0.000 claims 1
- 231100000168 Stevens-Johnson syndrome Toxicity 0.000 claims 1
- 206010072148 Stiff-Person syndrome Diseases 0.000 claims 1
- 206010042674 Swelling Diseases 0.000 claims 1
- 206010042742 Sympathetic ophthalmia Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 208000031981 Thrombocytopenic Idiopathic Purpura Diseases 0.000 claims 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 206010070517 Type 2 lepra reaction Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 206010046914 Vaginal infection Diseases 0.000 claims 1
- 201000008100 Vaginitis Diseases 0.000 claims 1
- 206010047124 Vasculitis necrotising Diseases 0.000 claims 1
- 206010047642 Vitiligo Diseases 0.000 claims 1
- 201000009961 allergic asthma Diseases 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 230000007815 allergy Effects 0.000 claims 1
- 231100000360 alopecia Toxicity 0.000 claims 1
- 208000002399 aphthous stomatitis Diseases 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 201000000448 autoimmune hemolytic anemia Diseases 0.000 claims 1
- 201000004982 autoimmune uveitis Diseases 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 230000002146 bilateral effect Effects 0.000 claims 1
- 208000020670 canker sore Diseases 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 230000007969 cellular immunity Effects 0.000 claims 1
- 208000019069 chronic childhood arthritis Diseases 0.000 claims 1
- 208000025302 chronic primary adrenal insufficiency Diseases 0.000 claims 1
- 208000004921 cutaneous lupus erythematosus Diseases 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 201000002491 encephalomyelitis Diseases 0.000 claims 1
- 230000002449 erythroblastic effect Effects 0.000 claims 1
- 230000003890 fistula Effects 0.000 claims 1
- 231100000869 headache Toxicity 0.000 claims 1
- 230000002008 hemorrhagic effect Effects 0.000 claims 1
- 230000004957 immunoregulator effect Effects 0.000 claims 1
- 230000036512 infertility Effects 0.000 claims 1
- 208000000509 infertility Diseases 0.000 claims 1
- 231100000535 infertility Toxicity 0.000 claims 1
- 230000006749 inflammatory damage Effects 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 201000004614 iritis Diseases 0.000 claims 1
- 201000002215 juvenile rheumatoid arthritis Diseases 0.000 claims 1
- 206010023332 keratitis Diseases 0.000 claims 1
- 201000010666 keratoconjunctivitis Diseases 0.000 claims 1
- 201000011486 lichen planus Diseases 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 206010028417 myasthenia gravis Diseases 0.000 claims 1
- 230000008693 nausea Effects 0.000 claims 1
- 230000002956 necrotizing effect Effects 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000000750 progressive effect Effects 0.000 claims 1
- 201000003068 rheumatic fever Diseases 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 231100000879 sensorineural hearing loss Toxicity 0.000 claims 1
- 208000023573 sensorineural hearing loss disease Diseases 0.000 claims 1
- 230000008961 swelling Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 206010043778 thyroiditis Diseases 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/121,481 US7211258B2 (en) | 2002-04-10 | 2002-04-10 | Protein A compositions and methods of use |
| PCT/US2003/007019 WO2003086317A2 (en) | 2002-04-10 | 2003-03-06 | Protein a compositions and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009256593A Division JP5523796B2 (ja) | 2002-04-10 | 2009-11-09 | プロテインａ組成物および使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005527581A JP2005527581A (ja) | 2005-09-15 |
| JP2005527581A5 true JP2005527581A5 (enExample) | 2006-04-13 |
| JP4598404B2 JP4598404B2 (ja) | 2010-12-15 |
Family
ID=29248302
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003583342A Expired - Fee Related JP4598404B2 (ja) | 2002-04-10 | 2003-03-06 | プロテインａ組成物および使用方法 |
| JP2009256593A Expired - Lifetime JP5523796B2 (ja) | 2002-04-10 | 2009-11-09 | プロテインａ組成物および使用方法 |
| JP2013227980A Withdrawn JP2014024865A (ja) | 2002-04-10 | 2013-11-01 | プロテインａ組成物および使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009256593A Expired - Lifetime JP5523796B2 (ja) | 2002-04-10 | 2009-11-09 | プロテインａ組成物および使用方法 |
| JP2013227980A Withdrawn JP2014024865A (ja) | 2002-04-10 | 2013-11-01 | プロテインａ組成物および使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US7211258B2 (enExample) |
| EP (2) | EP2570136B1 (enExample) |
| JP (3) | JP4598404B2 (enExample) |
| AU (1) | AU2003220085A1 (enExample) |
| CA (2) | CA2894098C (enExample) |
| ES (2) | ES2629687T3 (enExample) |
| WO (1) | WO2003086317A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7425331B2 (en) * | 2002-04-10 | 2008-09-16 | Protalex, Inc. | Protein A methods of use |
| US7211258B2 (en) * | 2002-04-10 | 2007-05-01 | Protalex, Inc. | Protein A compositions and methods of use |
| WO2004093907A2 (en) * | 2003-04-23 | 2004-11-04 | Tomoaki Hoshino | Therapeutic agents for treating dermatitis, alopecia and itching and transgenic animals for evaluating such therapeutic agents |
| US7691608B2 (en) * | 2006-12-06 | 2010-04-06 | Repligen Corporation | Nucleic acids encoding recombinant protein A |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2853453A1 (de) * | 1978-12-11 | 1980-06-19 | Behringwerke Ag | Mittel zur therapie von immunkomplexerkrankungen |
| US4315028A (en) * | 1978-12-22 | 1982-02-09 | Scheinberg Israel H | Method of treatment of rheumatoid arthritis |
| US5189014A (en) * | 1979-12-03 | 1993-02-23 | Cowan Jr Fred M | Method of treating cellular Fc receptor mediated hypersensitivity immune disorders |
| US4355029A (en) * | 1981-06-01 | 1982-10-19 | Eli Lilly And Company | Combination therapy for rheumatoid arthritis |
| US5091091A (en) | 1981-11-06 | 1992-02-25 | Terman David S | Protein A perfusion and post perfusion drug infusion |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| US4402965A (en) * | 1982-08-05 | 1983-09-06 | John R. A. Simoons | Treatment of rheumatoid arthritis and related diseases |
| US4699783A (en) * | 1983-03-11 | 1987-10-13 | Terman David S | Products and methods for treatment of cancer |
| US4617266A (en) | 1983-04-28 | 1986-10-14 | Genex Corporation | Production of Protein A |
| FR2556219B1 (fr) * | 1983-12-07 | 1987-06-26 | Merieux Inst | Nouveau medicament immunomodulateur, a base de fragments fc d'igg humaines |
| US4681870A (en) * | 1985-01-11 | 1987-07-21 | Imre Corporation | Protein A-silica immunoadsorbent and process for its production |
| US4628052A (en) * | 1985-05-28 | 1986-12-09 | Peat Raymond F | Pharmaceutical compositions containing dehydroepiandrosterone and other anesthetic steroids in the treatment of arthritis and other joint disabilities |
| DK528285D0 (da) * | 1985-11-15 | 1985-11-15 | Novo Industri As | Peptider samt praeparater indeholdende disse |
| US5985599A (en) * | 1986-05-29 | 1999-11-16 | The Austin Research Institute | FC receptor for immunoglobulin |
| US5362490A (en) * | 1986-07-25 | 1994-11-08 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Human myelomonocyte interferon-gamma, and process for preparation and use thereof |
| US5782792A (en) * | 1986-11-21 | 1998-07-21 | Cypress Bioscience, Inc. | Method for treatment of rheumatoid arthritis |
| US4863869A (en) * | 1986-11-21 | 1989-09-05 | Imre Cororation | Anti-human IGM immunoadsorbent and process for producing said immunoadsorbent |
| US5122112A (en) * | 1986-11-21 | 1992-06-16 | Imre Corporation | Antigen-specific removal of circulating immune complexes |
| US5084559A (en) * | 1987-03-27 | 1992-01-28 | Repligen Corporation | Protein a domain mutants |
| US4925920A (en) * | 1987-05-29 | 1990-05-15 | Brigham And Women's Hospital | Immunosuppressive polypeptides |
| US5084398A (en) * | 1987-11-20 | 1992-01-28 | Creative Biomolecules | Selective removal of immune complexes |
| JPH0211523A (ja) * | 1988-06-30 | 1990-01-16 | Sekisui Chem Co Ltd | 悪性腫瘍等の治療用免疫吸着剤およびそれを用いた治療方法 |
| US5240601A (en) * | 1988-11-09 | 1993-08-31 | Chembiomed, Ltd. | Affinity supports for hemoperfusion |
| US5077284A (en) * | 1988-12-30 | 1991-12-31 | Loria Roger M | Use of dehydroepiandrosterone to improve immune response |
| US6042837A (en) * | 1989-09-20 | 2000-03-28 | Kalland; Terje | Methods of staphylococcal enterotoxin directed cell-mediated cytotoxicity (SDCC) |
| US5728388A (en) * | 1989-10-03 | 1998-03-17 | Terman; David S. | Method of cancer treatment |
| US6126945A (en) * | 1989-10-03 | 2000-10-03 | Pharmacia Ab | Tumor killing effects of enterotoxins, superantigens, and related compounds |
| GB9013872D0 (en) | 1990-06-21 | 1990-08-15 | Inst Tecnologico Y Cientifico | Use of protein a and polypeptide components thereof in the treatment of tumours |
| US5230887A (en) * | 1990-07-11 | 1993-07-27 | Immune Network Research Ltd. | Immune system stabilizers for prevention and therapy of disorders associated with immune system disfunction |
| GB9022648D0 (en) * | 1990-10-18 | 1990-11-28 | Charing Cross Sunley Research | Polypeptide and its use |
| US5476929A (en) | 1991-02-15 | 1995-12-19 | Uab Research Foundation | Structural gene of pneumococcal protein |
| WO1992019240A1 (en) * | 1991-05-01 | 1992-11-12 | University Of New Mexico | Treatment of aberrant cellular states with biomodulators |
| US5422427A (en) | 1991-09-17 | 1995-06-06 | The United States Of America As Represented By The United States Department Of Health And Human Services | Pneumococcal fimbrial protein A |
| US6312944B1 (en) | 1991-11-14 | 2001-11-06 | The United States Of America As Represented By The Department Of Health And Human Services | Pneumococcal fimbrial protein A |
| US5277701A (en) * | 1991-11-15 | 1994-01-11 | Regents Of The University Of Minnesota | Treatment of aluimmunization and refractoriness to platelet transfusion by protein A column therapy |
| US5304529A (en) * | 1992-03-30 | 1994-04-19 | Tropicana Products, Inc. | Synergistic mixture of bioregulator compounds and method of their use |
| JP3714683B2 (ja) * | 1992-07-30 | 2005-11-09 | 生化学工業株式会社 | 抗リウマチ剤 |
| CA2105629A1 (en) * | 1992-09-14 | 1994-03-15 | Robert S. Becker | Potentiation of immunogenic response |
| AU5152293A (en) * | 1992-10-08 | 1994-05-09 | Kennedy Institute Of Rheumatology, The | Treatment of autoimmune and inflammatory disorders |
| US5753227A (en) * | 1993-07-23 | 1998-05-19 | Strahilevitz; Meir | Extracorporeal affinity adsorption methods for the treatment of atherosclerosis, cancer, degenerative and autoimmune diseases |
| US5858981A (en) * | 1993-09-30 | 1999-01-12 | University Of Pennsylvania | Method of inhibiting phagocytosis |
| GB9320820D0 (en) * | 1993-10-08 | 1993-12-01 | Biokine Tech Ltd | Compounds for medicinal use |
| CA2176948C (en) * | 1993-11-30 | 2007-05-15 | Halle Morton | Chaperonin 10 |
| JP3574471B2 (ja) * | 1994-05-18 | 2004-10-06 | 株式会社クラレ | 抗表皮細胞間抗体結合性ペプチドおよび吸着剤 |
| CN1136016C (zh) * | 1995-07-10 | 2004-01-28 | 旭医学株式会社 | 用于治疗炎性疾病的体外循环血液处理系统 |
| US6447777B1 (en) * | 1996-03-29 | 2002-09-10 | David S. Terman | Polymerized staphylococcal protein a for treatment of diseases |
| US6013763A (en) * | 1996-06-04 | 2000-01-11 | Genentech, Inc. | Peptide variants of protein A |
| US6245340B1 (en) * | 1996-12-03 | 2001-06-12 | Parvin Youssefyeh | Method of improving the immune response and compositions therefor |
| US6555661B1 (en) * | 1997-08-25 | 2003-04-29 | Anthony R. Torres | Simple, environmentally benign, method for purifying protein A |
| WO2000069457A1 (en) | 1999-05-15 | 2000-11-23 | University Of California, San Diego | Protein a based binding domains with desirable activities |
| US7163686B1 (en) * | 1999-05-15 | 2007-01-16 | The Regents Of The University Of California | Protein A based binding domains with desirable activities |
| US7211258B2 (en) | 2002-04-10 | 2007-05-01 | Protalex, Inc. | Protein A compositions and methods of use |
| US7425331B2 (en) | 2002-04-10 | 2008-09-16 | Protalex, Inc. | Protein A methods of use |
-
2002
- 2002-04-10 US US10/121,481 patent/US7211258B2/en not_active Expired - Lifetime
-
2003
- 2003-03-06 ES ES03716375.5T patent/ES2629687T3/es not_active Expired - Lifetime
- 2003-03-06 CA CA2894098A patent/CA2894098C/en not_active Expired - Fee Related
- 2003-03-06 JP JP2003583342A patent/JP4598404B2/ja not_active Expired - Fee Related
- 2003-03-06 EP EP12177657.9A patent/EP2570136B1/en not_active Expired - Lifetime
- 2003-03-06 AU AU2003220085A patent/AU2003220085A1/en not_active Abandoned
- 2003-03-06 ES ES12177657.9T patent/ES2586120T3/es not_active Expired - Lifetime
- 2003-03-06 EP EP03716375.5A patent/EP1499345B1/en not_active Expired - Lifetime
- 2003-03-06 CA CA2481282A patent/CA2481282C/en not_active Expired - Fee Related
- 2003-03-06 WO PCT/US2003/007019 patent/WO2003086317A2/en not_active Ceased
-
2006
- 2006-11-14 US US11/559,713 patent/US7807170B2/en not_active Expired - Fee Related
-
2009
- 2009-11-09 JP JP2009256593A patent/JP5523796B2/ja not_active Expired - Lifetime
-
2010
- 2010-09-14 US US12/882,057 patent/US8168189B2/en not_active Expired - Fee Related
-
2012
- 2012-04-23 US US13/453,788 patent/US8603486B2/en not_active Expired - Fee Related
-
2013
- 2013-11-01 JP JP2013227980A patent/JP2014024865A/ja not_active Withdrawn
- 2013-12-05 US US14/098,146 patent/US9370552B2/en not_active Expired - Fee Related
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