JP2005527209A - 疼痛管理のためのプロテインキナーゼＣγのペプチドインヒビター - Google Patents
疼痛管理のためのプロテインキナーゼＣγのペプチドインヒビター Download PDFInfo
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- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US37453002P | 2002-04-22 | 2002-04-22 | |
| PCT/US2003/012542 WO2003089457A2 (en) | 2002-04-22 | 2003-04-22 | Peptide inhibitors of protein kinase c ϝ for pain management |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2009010402A Division JP2009091372A (ja) | 2002-04-22 | 2009-01-20 | 疼痛管理のためのプロテインキナーゼＣγのペプチドインヒビター |
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| JP2005527209A true JP2005527209A (ja) | 2005-09-15 |
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| JP2003586176A Withdrawn JP2005523326A (ja) | 2002-04-22 | 2003-04-22 | プロテインキナーゼｃのペプチドインヒビター |
| JP2009010402A Pending JP2009091372A (ja) | 2002-04-22 | 2009-01-20 | 疼痛管理のためのプロテインキナーゼＣγのペプチドインヒビター |
| JP2009011456A Pending JP2009102392A (ja) | 2002-04-22 | 2009-01-21 | プロテインキナーゼｃのペプチドインヒビター |
| JP2012128849A Pending JP2012176978A (ja) | 2002-04-22 | 2012-06-06 | プロテインキナーゼｃのペプチドインヒビター |
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| JP2009010402A Pending JP2009091372A (ja) | 2002-04-22 | 2009-01-20 | 疼痛管理のためのプロテインキナーゼＣγのペプチドインヒビター |
| JP2009011456A Pending JP2009102392A (ja) | 2002-04-22 | 2009-01-21 | プロテインキナーゼｃのペプチドインヒビター |
| JP2012128849A Pending JP2012176978A (ja) | 2002-04-22 | 2012-06-06 | プロテインキナーゼｃのペプチドインヒビター |
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| US (8) | US7459424B2 (https=) |
| EP (3) | EP1501533A4 (https=) |
| JP (5) | JP2005527209A (https=) |
| AU (4) | AU2003234185C1 (https=) |
| CA (3) | CA2482598C (https=) |
| WO (2) | WO2003089456A2 (https=) |
Cited By (4)
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| JP2006525948A (ja) * | 2003-05-16 | 2006-11-16 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 離脱症状における使用のためのプロテインキナーゼｃペプチド |
| JP2010516707A (ja) * | 2007-01-19 | 2010-05-20 | カイ ファーマシューティカルズ インコーポレーティッド | ペプチド組成物の安定性および送達効率を上昇させるための修飾方法 |
| JP2010516709A (ja) * | 2007-01-19 | 2010-05-20 | カイ ファーマシューティカルズ インコーポレーティッド | 疼痛減弱のためのイプシロン阻害化合物の使用方法 |
| JP2010523598A (ja) * | 2007-04-06 | 2010-07-15 | カイ・ファーマシューティカルズ・インコーポレイテッド | 痛みの軽減のためのガンマ阻害剤化合物の使用方法 |
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| JP2005527209A (ja) * | 2002-04-22 | 2005-09-15 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 疼痛管理のためのプロテインキナーゼＣγのペプチドインヒビター |
| US6933275B2 (en) * | 2002-05-01 | 2005-08-23 | The Board Of Trustees Of The Leland Stanford Junior University | Protein kinase C peptides for use in withdrawal |
| WO2004084889A1 (en) * | 2003-03-28 | 2004-10-07 | Pfizer Inc. | Use of protein kinase c inhibitor for suppressing sustained slow postsynaptic excitation (sspe) of enteric neurons |
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| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
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| CA2543257C (en) | 2003-10-24 | 2013-12-31 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
| US20090123468A1 (en) | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| CA2549052A1 (en) * | 2003-12-11 | 2005-06-30 | The Board Of Trustees Of The Leland Stanford Junior University | Isozyme-specific antagonists of protein kinase c |
| US7265092B2 (en) | 2004-09-30 | 2007-09-04 | Kai Pharmaceuticals, Inc. | Pharmaceutical formulation |
| US20060148700A1 (en) * | 2004-11-10 | 2006-07-06 | Daria Mochly-Rosen | Methods and compositions for reducing injury to a transplanted organ |
| US20060160062A1 (en) * | 2005-01-14 | 2006-07-20 | Young Lindon H | Perfusion and/or preservation solution for organs |
| EP1877424A4 (en) * | 2005-04-11 | 2010-09-29 | Pharmagap Inc | INHIBITORS OF PROTEIN KINASES AND USES THEREOF |
| EP2298792A3 (en) | 2005-08-05 | 2011-10-19 | Pharmagap Inc. | Peptides targeted to protein kinase C isoforms and uses thereof |
| JP5276982B2 (ja) | 2005-08-26 | 2013-08-28 | ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | オキシトシンの投与による頭痛の処置のための方法 |
| CA2644089A1 (en) * | 2005-09-19 | 2007-03-29 | Kai Pharmaceuticals, Inc. | Protein kinase c peptide modulators of angiogenesis |
| JP2009531335A (ja) * | 2006-03-30 | 2009-09-03 | サルペップ バイオテクノロジー インコーポレイテッド | 神経障害性疼痛の抑制および治療 |
| US7741290B2 (en) * | 2006-06-01 | 2010-06-22 | The Board of Trustee of The Leland Stanford Juinior University | Method of preventing progression of hypertension-induced heart failure with PKC peptides |
| US20090062208A1 (en) * | 2007-02-06 | 2009-03-05 | Mochly-Rosen Daria D | Methods for maintaining blood-brain barrier integrity in hypertensive subjects using a delta-PKC inhibitor |
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| US8975237B2 (en) | 2007-12-21 | 2015-03-10 | Coda Therapeutics, Inc. | Treatment of fibrotic conditions |
| US20090318351A1 (en) * | 2008-03-12 | 2009-12-24 | Kevin Grimes | Method of treating acute st-elevation myocardial infarction with a delta pkc antagonist |
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| WO2010019965A1 (en) * | 2008-08-15 | 2010-02-18 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for modulating epsilon protein kinase c-mediated cytoprotection |
| WO2010096746A1 (en) | 2009-02-20 | 2010-08-26 | Cellular Dynamics International, Inc. | Methods and compositions for the differentiation of stem cells |
| KR101720961B1 (ko) | 2009-02-27 | 2017-03-29 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 다능성 세포의 분화 |
| JP2012519710A (ja) * | 2009-03-06 | 2012-08-30 | アングストロム プハルマセウトイカルス インコーポレイテッド | 細胞遊走を調整するための組成物、及び方法 |
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| EP2482837A4 (en) | 2009-09-29 | 2013-05-22 | Joslin Diabetes Center Inc | USE OF PROTEIN KINASE C-DELTA (PKCD) INHIBITORS FOR THE TREATMENT OF DIABETES, ADIPOSITAS AND LIVER VARIATION |
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| US8785648B1 (en) | 2010-08-10 | 2014-07-22 | The Regents Of The University Of California | PKC-epsilon inhibitors |
| EP2742057B1 (en) | 2011-08-12 | 2016-04-20 | The Board of Trustees of The Leland Stanford Junior University | Compositions and methods for specific regulation of pyruvate dehydrogenase kinase |
| WO2013163171A1 (en) | 2012-04-24 | 2013-10-31 | Kaufman Dan S | Method for developing natural killer cells from stem cells |
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| CA2958704A1 (en) | 2014-08-25 | 2016-03-03 | University Of Canberra | Compositions for modulating cancer stem cells and uses therefor |
| SG11201705591PA (en) | 2015-01-07 | 2017-08-30 | Trigemina Inc | Magnesium-containing oxytocin formulations and methods of use |
| JP7093559B2 (ja) | 2016-04-12 | 2022-06-30 | トライジェミナ， インコーポレイテッド | マグネシウム含有オキシトシン製剤および使用の方法 |
| US12410143B2 (en) | 2017-01-17 | 2025-09-09 | Michael David FORREST | Therapeutic inhibitors of the reverse mode of ATP synthase |
| BR112019028172A2 (pt) | 2017-07-13 | 2020-10-06 | Michael David Forrest | moduladores terapêuticos do modo reverso da atp sintase |
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2003
- 2003-04-22 JP JP2003586177A patent/JP2005527209A/ja active Pending
- 2003-04-22 CA CA2482598A patent/CA2482598C/en not_active Expired - Fee Related
- 2003-04-22 AU AU2003234185A patent/AU2003234185C1/en not_active Ceased
- 2003-04-22 EP EP03728495A patent/EP1501533A4/en not_active Withdrawn
- 2003-04-22 US US10/421,548 patent/US7459424B2/en not_active Expired - Fee Related
- 2003-04-22 JP JP2003586176A patent/JP2005523326A/ja not_active Withdrawn
- 2003-04-22 US US10/421,503 patent/US7507711B2/en not_active Expired - Fee Related
- 2003-04-22 CA CA2785889A patent/CA2785889A1/en not_active Abandoned
- 2003-04-22 CA CA2481512A patent/CA2481512C/en not_active Expired - Fee Related
- 2003-04-22 AU AU2003234186A patent/AU2003234186B2/en not_active Ceased
- 2003-04-22 WO PCT/US2003/012541 patent/WO2003089456A2/en not_active Ceased
- 2003-04-22 US US10/513,003 patent/US7393835B2/en not_active Expired - Fee Related
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- 2003-04-22 WO PCT/US2003/012542 patent/WO2003089457A2/en not_active Ceased
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2007
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2008
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2009
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2011
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2012
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2014
- 2014-02-21 US US14/187,070 patent/US9365837B2/en not_active Expired - Fee Related
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| WO2000004914A1 (en) * | 1998-07-21 | 2000-02-03 | Cytovia, Inc. | Novel fluorescence dyes and their applications for whole cell fluorescence screening assays for caspases, peptidases, proteases and other enzymes and the use thereof |
| JP2005523326A (ja) * | 2002-04-22 | 2005-08-04 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | プロテインキナーゼｃのペプチドインヒビター |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006525948A (ja) * | 2003-05-16 | 2006-11-16 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 離脱症状における使用のためのプロテインキナーゼｃペプチド |
| JP2010516707A (ja) * | 2007-01-19 | 2010-05-20 | カイ ファーマシューティカルズ インコーポレーティッド | ペプチド組成物の安定性および送達効率を上昇させるための修飾方法 |
| JP2010516709A (ja) * | 2007-01-19 | 2010-05-20 | カイ ファーマシューティカルズ インコーポレーティッド | 疼痛減弱のためのイプシロン阻害化合物の使用方法 |
| JP2014224126A (ja) * | 2007-01-19 | 2014-12-04 | カイ ファーマシューティカルズ インコーポレーティッド | ペプチド組成物の安定性および送達効率を上昇させるための修飾方法 |
| KR101775929B1 (ko) * | 2007-01-19 | 2017-09-07 | 카이 파마슈티컬즈 | 안정성 및 전달 효율을 증가시키기 위한 펩타이드 조성물의 변형 |
| JP2018111717A (ja) * | 2007-01-19 | 2018-07-19 | カイ ファーマシューティカルズ インコーポレーティッド | ペプチド組成物の安定性および送達効率を上昇させるための修飾方法 |
| KR20190140111A (ko) * | 2007-01-19 | 2019-12-18 | 카이 파마슈티컬즈 | 안정성 및 전달 효율을 증가시키기 위한 펩타이드 조성물의 변형 |
| JP2021098725A (ja) * | 2007-01-19 | 2021-07-01 | カイ ファーマシューティカルズ インコーポレーティッド | ペプチド組成物の安定性および送達効率を上昇させるための修飾方法 |
| KR102274003B1 (ko) | 2007-01-19 | 2021-07-08 | 카이 파마슈티컬즈 | 안정성 및 전달 효율을 증가시키기 위한 펩타이드 조성물의 변형 |
| JP2023078424A (ja) * | 2007-01-19 | 2023-06-06 | カイ ファーマシューティカルズ インコーポレーティッド | ペプチド組成物の安定性および送達効率を上昇させるための修飾方法 |
| JP2010523598A (ja) * | 2007-04-06 | 2010-07-15 | カイ・ファーマシューティカルズ・インコーポレイテッド | 痛みの軽減のためのガンマ阻害剤化合物の使用方法 |
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