JP2005526857A5 - - Google Patents
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- JP2005526857A5 JP2005526857A5 JP2004507431A JP2004507431A JP2005526857A5 JP 2005526857 A5 JP2005526857 A5 JP 2005526857A5 JP 2004507431 A JP2004507431 A JP 2004507431A JP 2004507431 A JP2004507431 A JP 2004507431A JP 2005526857 A5 JP2005526857 A5 JP 2005526857A5
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- Prior art keywords
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- 239000008194 pharmaceutical composition Substances 0.000 claims 29
- 125000001931 aliphatic group Chemical group 0.000 claims 28
- 150000001875 compounds Chemical class 0.000 claims 22
- 150000003839 salts Chemical class 0.000 claims 21
- 239000011780 sodium chloride Substances 0.000 claims 21
- 239000012453 solvate Substances 0.000 claims 21
- 125000005843 halogen group Chemical group 0.000 claims 16
- 125000001188 haloalkyl group Chemical group 0.000 claims 15
- 125000003118 aryl group Chemical group 0.000 claims 12
- 125000001072 heteroaryl group Chemical group 0.000 claims 9
- 125000001424 substituent group Chemical group 0.000 claims 9
- 125000004429 atoms Chemical group 0.000 claims 8
- 125000004438 haloalkoxy group Chemical group 0.000 claims 8
- 125000005842 heteroatoms Chemical group 0.000 claims 8
- -1 aliphatic ester Chemical class 0.000 claims 6
- 230000002401 inhibitory effect Effects 0.000 claims 6
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 5
- 200000000018 inflammatory disease Diseases 0.000 claims 5
- 210000000265 Leukocytes Anatomy 0.000 claims 4
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000005083 alkoxyalkoxy group Chemical group 0.000 claims 4
- 125000004414 alkyl thio group Chemical group 0.000 claims 4
- 125000003710 aryl alkyl group Chemical group 0.000 claims 4
- 125000002102 aryl alkyloxo group Chemical group 0.000 claims 4
- 125000004104 aryloxy group Chemical group 0.000 claims 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 4
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 4
- 125000006575 electron-withdrawing group Chemical group 0.000 claims 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 4
- 101700040666 ACKR2 Proteins 0.000 claims 3
- 102100008149 CCR9 Human genes 0.000 claims 3
- 101700076302 CCR9 Proteins 0.000 claims 3
- 125000005093 alkyl carbonyl alkyl group Chemical group 0.000 claims 3
- 230000027455 binding Effects 0.000 claims 3
- 125000000623 heterocyclic group Chemical group 0.000 claims 3
- 125000004971 nitroalkyl group Chemical group 0.000 claims 3
- 125000004385 trihaloalkyl group Chemical group 0.000 claims 3
- 102000004900 CC chemokine receptor 9 Human genes 0.000 claims 2
- 108090001026 CC chemokine receptor 9 Proteins 0.000 claims 2
- 206010011401 Crohn's disease Diseases 0.000 claims 2
- 210000004400 Mucous Membrane Anatomy 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 230000001404 mediated Effects 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 206010009839 Coeliac disease Diseases 0.000 claims 1
- 201000008260 Crohn's colitis Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000001624 naphthyl group Chemical group 0.000 claims 1
- 125000003373 pyrazinyl group Chemical group 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 125000000714 pyrimidinyl group Chemical group 0.000 claims 1
- 125000001544 thienyl group Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38357302P | 2002-05-24 | 2002-05-24 | |
| US60/383,573 | 2002-05-24 | ||
| PCT/US2003/016090 WO2003099773A1 (en) | 2002-05-24 | 2003-05-21 | Ccr9 inhibitors and methods of use thereof |
Related Child Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006124437A Division JP4818798B2 (ja) | 2002-05-24 | 2006-04-27 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2009235795A Division JP2010047584A (ja) | 2002-05-24 | 2009-10-09 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2010265823A Division JP5544283B2 (ja) | 2002-05-24 | 2010-11-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2011167759A Division JP5432221B2 (ja) | 2002-05-24 | 2011-07-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2011167760A Division JP5548169B2 (ja) | 2002-05-24 | 2011-07-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005526857A JP2005526857A (ja) | 2005-09-08 |
| JP2005526857A5 true JP2005526857A5 (US07794700-20100914-C00152.png) | 2006-06-22 |
| JP4828822B2 JP4828822B2 (ja) | 2011-11-30 |
Family
ID=29584585
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004507431A Expired - Lifetime JP4828822B2 (ja) | 2002-05-24 | 2003-05-21 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2006124437A Expired - Fee Related JP4818798B2 (ja) | 2002-05-24 | 2006-04-27 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2009235795A Pending JP2010047584A (ja) | 2002-05-24 | 2009-10-09 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2010265823A Expired - Fee Related JP5544283B2 (ja) | 2002-05-24 | 2010-11-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2011167759A Expired - Fee Related JP5432221B2 (ja) | 2002-05-24 | 2011-07-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2011167760A Expired - Fee Related JP5548169B2 (ja) | 2002-05-24 | 2011-07-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2014036198A Pending JP2014132018A (ja) | 2002-05-24 | 2014-02-27 | Ｃｃｒ９インヒビターおよびその使用方法 |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006124437A Expired - Fee Related JP4818798B2 (ja) | 2002-05-24 | 2006-04-27 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2009235795A Pending JP2010047584A (ja) | 2002-05-24 | 2009-10-09 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2010265823A Expired - Fee Related JP5544283B2 (ja) | 2002-05-24 | 2010-11-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2011167759A Expired - Fee Related JP5432221B2 (ja) | 2002-05-24 | 2011-07-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2011167760A Expired - Fee Related JP5548169B2 (ja) | 2002-05-24 | 2011-07-29 | Ｃｃｒ９インヒビターおよびその使用方法 |
| JP2014036198A Pending JP2014132018A (ja) | 2002-05-24 | 2014-02-27 | Ｃｃｒ９インヒビターおよびその使用方法 |
Country Status (9)
Families Citing this family (89)
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- 2003-05-21 EP EP11172254A patent/EP2402310A1/en not_active Withdrawn
- 2003-05-21 JP JP2004507431A patent/JP4828822B2/ja not_active Expired - Lifetime
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2004
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2006
- 2006-03-28 US US11/391,633 patent/US7282502B2/en not_active Expired - Lifetime
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2007
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2008
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2009
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- 2009-12-03 US US12/630,040 patent/US8030517B2/en not_active Expired - Fee Related
- 2009-12-17 US US12/640,439 patent/US7999109B2/en not_active Expired - Fee Related
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2010
- 2010-03-19 AU AU2010201073A patent/AU2010201073B2/en not_active Ceased
- 2010-08-26 US US12/869,070 patent/US20100324093A1/en not_active Abandoned
- 2010-11-29 JP JP2010265823A patent/JP5544283B2/ja not_active Expired - Fee Related
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2011
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2013
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2014
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2015
- 2015-04-15 US US14/687,303 patent/US20160068479A1/en not_active Abandoned
