HUE038700T2 - Benzofuran-2-szulfonamid származékok, mint kemokinreceptor-modulációk - Google Patents

Benzofuran-2-szulfonamid származékok, mint kemokinreceptor-modulációk

Info

Publication number
HUE038700T2
HUE038700T2 HUE13711995A HUE13711995A HUE038700T2 HU E038700 T2 HUE038700 T2 HU E038700T2 HU E13711995 A HUE13711995 A HU E13711995A HU E13711995 A HUE13711995 A HU E13711995A HU E038700 T2 HUE038700 T2 HU E038700T2
Authority
HU
Hungary
Prior art keywords
benzofuran
chemokine receptor
receptor modulators
sulfonamide derivatives
sulfonamide
Prior art date
Application number
HUE13711995A
Other languages
English (en)
Inventor
Haiqing Yuan
Richard L Beard
Xiaoxia Liu
John E Donello
Veena Viswanath
Michael E Garst
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of HUE038700T2 publication Critical patent/HUE038700T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HUE13711995A 2012-03-01 2013-03-01 Benzofuran-2-szulfonamid származékok, mint kemokinreceptor-modulációk HUE038700T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261605300P 2012-03-01 2012-03-01

Publications (1)

Publication Number Publication Date
HUE038700T2 true HUE038700T2 (hu) 2018-11-28

Family

ID=47902352

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE18156011A HUE049728T2 (hu) 2012-03-01 2013-03-01 Benzofurán-2-szulfonamid származékok, mint kemokin receptor modulátorok
HUE13711995A HUE038700T2 (hu) 2012-03-01 2013-03-01 Benzofuran-2-szulfonamid származékok, mint kemokinreceptor-modulációk

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE18156011A HUE049728T2 (hu) 2012-03-01 2013-03-01 Benzofurán-2-szulfonamid származékok, mint kemokin receptor modulátorok

Country Status (12)

Country Link
US (4) US8815915B2 (hu)
EP (2) EP2820010B1 (hu)
AU (2) AU2013225815B2 (hu)
CA (1) CA2866078C (hu)
CY (1) CY1120528T1 (hu)
DK (2) DK2820010T3 (hu)
ES (2) ES2791534T3 (hu)
HU (2) HUE049728T2 (hu)
PL (2) PL2820010T3 (hu)
PT (2) PT3345899T (hu)
SI (1) SI2820010T1 (hu)
WO (2) WO2013130958A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE049728T2 (hu) 2012-03-01 2020-10-28 Allergan Inc Benzofurán-2-szulfonamid származékok, mint kemokin receptor modulátorok
ES2708563T3 (es) * 2013-03-12 2019-04-10 Allergan Inc Derivados de sulfonamida como moduladores de receptores de quimiocinas
AR098583A1 (es) * 2013-12-02 2016-06-01 Allergan Inc Compuesto de sulfonamida de benzotiofeno, composición farmacéutica que lo comprende y su uso para la preparación de dicha composición

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003099773A1 (en) 2002-05-24 2003-12-04 Millennium Pharmaceuticals, Inc. Ccr9 inhibitors and methods of use thereof
US7420055B2 (en) 2002-11-18 2008-09-02 Chemocentryx, Inc. Aryl sulfonamides
US20070021466A1 (en) * 2002-11-18 2007-01-25 Solomon Ungashe CCR2 inhibitors and methods of use thereof
WO2005004810A2 (en) 2003-07-02 2005-01-20 Merck & Co., Inc. Arylsulfonamide derivatives
PT1651621E (pt) * 2003-08-08 2008-09-30 Janssen Pharmaceutica Nv Compostos de 2-(quinoxalin-5-ilsulfonilamino)-benzamida como moduladores de cck2
US7622583B2 (en) * 2005-01-14 2009-11-24 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2
US7931909B2 (en) 2005-05-10 2011-04-26 Allergan, Inc. Ocular therapy using alpha-2 adrenergic receptor compounds having enhanced anterior clearance rates
GB0524786D0 (en) * 2005-12-05 2006-01-11 Glaxo Group Ltd Compounds
NZ574759A (en) 2006-07-14 2010-10-29 Chemocentryx Inc Triazolyl phenyl benzenesulfonamides
WO2008008374A2 (en) 2006-07-14 2008-01-17 Chemocentryx, Inc. Ccr2 inhibitors and methods of use thereof
US8519135B2 (en) 2006-07-14 2013-08-27 Chemocentryx, Inc. Heteroaryl sulfonamides and CCR2/CCR9
EP2175859B1 (en) 2007-07-12 2012-03-07 ChemoCentryx, Inc. Fused heteroaryl pyridyl and phenyl benzenesulfonamides as ccr2 modulators for the treament of inflammation
TWI440638B (zh) 2007-10-30 2014-06-11 Otsuka Pharma Co Ltd 雜環化合物及其藥學組成物
CN108383828A (zh) * 2010-12-16 2018-08-10 阿勒根公司 作为趋化因子受体调节剂的新的1,2-双-磺酰胺衍生物
BR112013015234B1 (pt) * 2010-12-16 2020-04-22 Allergan Inc composto e composição farmacêutica
CA2859024C (en) * 2011-12-12 2016-11-08 Allergan, Inc. Benzisothiazol-3(1h)-one-5-sulfonyl derivatives as chemokine receptor modulators
HUE049728T2 (hu) * 2012-03-01 2020-10-28 Allergan Inc Benzofurán-2-szulfonamid származékok, mint kemokin receptor modulátorok
ES2708563T3 (es) * 2013-03-12 2019-04-10 Allergan Inc Derivados de sulfonamida como moduladores de receptores de quimiocinas

Also Published As

Publication number Publication date
US8927544B2 (en) 2015-01-06
WO2013130962A1 (en) 2013-09-06
WO2013130958A1 (en) 2013-09-06
US9416120B2 (en) 2016-08-16
DK2820010T3 (en) 2018-08-06
EP2820010A1 (en) 2015-01-07
SI2820010T1 (sl) 2018-11-30
AU2018200226A1 (en) 2018-01-25
CA2866078C (en) 2018-01-02
CY1120528T1 (el) 2019-07-10
DK3345899T3 (da) 2020-05-11
US8815915B2 (en) 2014-08-26
PT3345899T (pt) 2020-05-20
US20130231339A1 (en) 2013-09-05
CA2866078A1 (en) 2013-09-06
US9550746B2 (en) 2017-01-24
EP3345899B1 (en) 2020-02-19
US20140329813A1 (en) 2014-11-06
US20150218119A1 (en) 2015-08-06
PL2820010T3 (pl) 2018-11-30
PL3345899T3 (pl) 2020-07-27
US20130231338A1 (en) 2013-09-05
EP2820010B1 (en) 2018-05-09
HUE049728T2 (hu) 2020-10-28
AU2013225815B2 (en) 2017-10-12
EP3345899A1 (en) 2018-07-11
PT2820010T (pt) 2018-10-01
AU2013225815A1 (en) 2014-09-25
ES2791534T3 (es) 2020-11-04
AU2018200226B2 (en) 2019-09-19
ES2683046T3 (es) 2018-09-24

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