JP2005522287A - 血液成分の分離方法および装置 - Google Patents
血液成分の分離方法および装置 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/15003—Source of blood for venous or arterial blood
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150038—Source of blood for blood from umbilical cord
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- A—HUMAN NECESSITIES
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- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150045—Source of blood for blood from vagina, placenta, colon or mouth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150366—Blood collection bags, e.g. connected to the patient by a catheter comprising means for removing a small sample of collected blood from the bag
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150503—Single-ended needles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0231—Multiple bag systems for separating or storing blood components with gas separating means, e.g. air outlet through microporous membrane or gas bag
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/029—Separating blood components present in distinct layers in a container, not otherwise provided for
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/34—Controlling the feed distribution; Controlling the liquid level ; Control of process parameters
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- B04B5/0428—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles with flexible receptacles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0462—Placental blood, umbilical cord blood
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
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Abstract
Description
Claims (7)
- 第一および第二のバッグにつながった遠心分離バッグと、
血液を前記遠心分離バッグに入れる入口と、
前記遠心分離バッグから前記赤血球バッグと白血球バッグとにつながった導管と、
血液画分を前記第一および第二のバッグに入れるための機械制御で作動するバルブ手段とを組み合わせて有してなる、バッグセット。 - 前記遠心分離バッグと前記赤血球バッグおよび白血球バッグを納める前記バッグセット用ホルダであって、前記バッグセットの前記バルブ手段が前記ホルダと連通しており、かつ前記ホルダに配置されたモータに作動可能に結合されたホルダと、
前記ホルダに設けられたセンサであって、前記センサが赤血球から白血球への遷移を検出して、前記モータによって前記バルブ手段を前記赤血球バッグから前記白血球バッグに切り替えるセンサとをさらに含む、請求項1記載のバッグセット。 - 血球を分離するためのシステムであって、
遠心分離器と、
複数の互いに連絡するバッグを有するバッグセットと、
前記遠心分離器に受け入れられる形状を有するバッグセットコンテナであって、前記コンテナは前記バッグセット内の各バッグ間の連絡を選択的に提供する手段を含むコンテナとを組み合わせて有してなる、血球を分離するためのシステム。 - 前記バッグセットが第一、第二、および第三のバッグを含み、前記第二および第三のバッグは選択的に前記第一のバッグと連通し、
検知手段が、前記第一のバッグと、前記検知手段に応答して前記第二のバッグと第三のバッグに流れを指向させる手段とを監視する、請求項3記載のシステム。 - 前記検知手段は、前記遠心分離器に納まるような寸法を有するバッグセットホルダ内に配置され、
前記指向手段は、前記ホルダに設けられた駆動モータ、および前記バッグセットの通路に配されたバルブを含む、請求項4記載のシステム。 - 血球を分離するための方法であって、
血球の混合物を遠心分離して層別化を起こさせ、前記層別化により第一の血球層と第二の血球層とが生じさせるステップと、
第一の血球バッグにつながった導管を開くステップと、
遠心分離によって第一の血球層を第一の血球バッグに入れるステップと、
第一の血球バッグにつながった導管を閉じるステップと、
第二の血球バッグにつながった導管を開くステップと、
遠心分離によって第二の血球層を第二の血球バッグに入れるステップとを含む、方法。 - 層別化を検知するステップと、
第一の血球層を第一の血球バッグに入れる遠心分離の完了に基づいて、モータに指示してバルブを前記第一のバッグから前記第二のバッグに切り替えるステップとをさらに含む、請求項6記載の方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/118,291 US7241281B2 (en) | 2002-04-08 | 2002-04-08 | Blood component separation method and apparatus |
PCT/US2003/008830 WO2003086574A1 (en) | 2002-04-08 | 2003-04-08 | Blood component separation method and apparatus |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2005522287A true JP2005522287A (ja) | 2005-07-28 |
JP4514456B2 JP4514456B2 (ja) | 2010-07-28 |
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ID=28674395
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003583581A Expired - Lifetime JP4514456B2 (ja) | 2002-04-08 | 2003-04-08 | 血液成分の分離方法および装置 |
Country Status (6)
Country | Link |
---|---|
US (3) | US7241281B2 (ja) |
EP (1) | EP1492605B1 (ja) |
JP (1) | JP4514456B2 (ja) |
CN (1) | CN1658941A (ja) |
AU (1) | AU2003222039A1 (ja) |
WO (1) | WO2003086574A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JPWO2020184020A1 (ja) * | 2019-03-14 | 2021-03-18 | テルモ株式会社 | 血液バッグシステム |
JP2021525876A (ja) * | 2018-06-01 | 2021-09-27 | カナディアン ブラッド サービシーズ | 血液製剤を品質評価するための非破壊サンプリングシステムおよび方法、ならびにそのためのサンプリングシステム |
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JPWO2020184020A1 (ja) * | 2019-03-14 | 2021-03-18 | テルモ株式会社 | 血液バッグシステム |
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AU2003222039A1 (en) | 2003-10-27 |
EP1492605A1 (en) | 2005-01-05 |
JP4514456B2 (ja) | 2010-07-28 |
US20070269887A1 (en) | 2007-11-22 |
US20120171762A1 (en) | 2012-07-05 |
US9050422B2 (en) | 2015-06-09 |
US20030191005A1 (en) | 2003-10-09 |
CN1658941A (zh) | 2005-08-24 |
EP1492605B1 (en) | 2015-06-17 |
US8167139B2 (en) | 2012-05-01 |
WO2003086574A1 (en) | 2003-10-23 |
US7241281B2 (en) | 2007-07-10 |
EP1492605A4 (en) | 2011-10-05 |
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