JPS55116259A
(en)
|
1979-03-01 |
1980-09-06 |
Fuji Photo Film Co Ltd |
Microimmunoassay method
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
DE3170135D1
(en)
|
1980-09-02 |
1985-05-30 |
Fuji Photo Film Co Ltd |
Method for immunochemical measurement of trace components
|
US4355153A
(en)
|
1980-11-19 |
1982-10-19 |
Societa' Italiana Resine S.I.R. S.P.A. |
Process for the polymerization of formaldehyde
|
CA1253129A
(en)
*
|
1984-02-09 |
1989-04-25 |
Thomas R. Jones |
Porous inorganic materials
|
US4957858A
(en)
*
|
1986-04-16 |
1990-09-18 |
The Salk Instute For Biological Studies |
Replicative RNA reporter systems
|
US5288641A
(en)
|
1984-06-04 |
1994-02-22 |
Arch Development Corporation |
Herpes Simplex virus as a vector
|
US4818681A
(en)
*
|
1985-02-22 |
1989-04-04 |
Molecular Diagnostics, Inc. |
Fast and specific immobilization of nucleic acids to solid supports
|
US4683195A
(en)
|
1986-01-30 |
1987-07-28 |
Cetus Corporation |
Process for amplifying, detecting, and/or-cloning nucleic acid sequences
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
US5641630A
(en)
*
|
1985-06-13 |
1997-06-24 |
Amgen Inc. |
Method and kit for performing nucleic acid hybridization assays
|
US4806631A
(en)
*
|
1985-09-30 |
1989-02-21 |
Miles Inc. |
Immobilization of nucleic acids on solvolyzed nylon supports
|
US4652613A
(en)
|
1985-12-16 |
1987-03-24 |
Celanese Corporation |
Novel elastomer/oxymethylene polymer blends containing polymeric compatibilizing agents
|
US5721098A
(en)
*
|
1986-01-16 |
1998-02-24 |
The Regents Of The University Of California |
Comparative genomic hybridization
|
US4937188A
(en)
*
|
1986-04-15 |
1990-06-26 |
Northeastern University |
Enzyme activity amplification method for increasing assay sensitivity
|
US5190864A
(en)
*
|
1986-04-15 |
1993-03-02 |
Northeastern University |
Enzyme amplification by using free enzyme to release enzyme from an immobilized enzyme material
|
US5268486A
(en)
|
1986-04-18 |
1993-12-07 |
Carnegie-Mellon Unversity |
Method for labeling and detecting materials employing arylsulfonate cyanine dyes
|
US6048982A
(en)
|
1986-04-18 |
2000-04-11 |
Carnegie Mellon University |
Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
|
US5151507A
(en)
|
1986-07-02 |
1992-09-29 |
E. I. Du Pont De Nemours And Company |
Alkynylamino-nucleotides
|
US5047519A
(en)
|
1986-07-02 |
1991-09-10 |
E. I. Du Pont De Nemours And Company |
Alkynylamino-nucleotides
|
US5135717A
(en)
|
1986-12-24 |
1992-08-04 |
British Technology Group Usa Inc. |
Tetrabenztriazaporphyrin reagents and kits containing the same
|
US4774339A
(en)
|
1987-08-10 |
1988-09-27 |
Molecular Probes, Inc. |
Chemically reactive dipyrrometheneboron difluoride dyes
|
DE3880273T2
(de)
*
|
1987-11-27 |
1993-07-29 |
Ecc Int Ltd |
Poroese anorganische materialien.
|
GB8803413D0
(en)
*
|
1988-02-15 |
1988-03-16 |
Ecc Int Ltd |
Biological support
|
US5700637A
(en)
|
1988-05-03 |
1997-12-23 |
Isis Innovation Limited |
Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
|
US6054270A
(en)
*
|
1988-05-03 |
2000-04-25 |
Oxford Gene Technology Limited |
Analying polynucleotide sequences
|
US5024933A
(en)
*
|
1988-05-10 |
1991-06-18 |
Enzo Biochem, Inc. |
Method and kit for sample adherence to test substrate
|
US5602244A
(en)
|
1988-05-26 |
1997-02-11 |
Competitive Technologies, Inc. |
Polynucleotide phosphorodithioate compounds
|
WO1990009441A1
(en)
|
1989-02-01 |
1990-08-23 |
The General Hospital Corporation |
Herpes simplex virus type i expression vector
|
US5925525A
(en)
*
|
1989-06-07 |
1999-07-20 |
Affymetrix, Inc. |
Method of identifying nucleotide differences
|
US6379895B1
(en)
*
|
1989-06-07 |
2002-04-30 |
Affymetrix, Inc. |
Photolithographic and other means for manufacturing arrays
|
US5527681A
(en)
|
1989-06-07 |
1996-06-18 |
Affymax Technologies N.V. |
Immobilized molecular synthesis of systematically substituted compounds
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
US6040138A
(en)
*
|
1995-09-15 |
2000-03-21 |
Affymetrix, Inc. |
Expression monitoring by hybridization to high density oligonucleotide arrays
|
US5800992A
(en)
*
|
1989-06-07 |
1998-09-01 |
Fodor; Stephen P.A. |
Method of detecting nucleic acids
|
US6309822B1
(en)
*
|
1989-06-07 |
2001-10-30 |
Affymetrix, Inc. |
Method for comparing copy number of nucleic acid sequences
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
DE3929150A1
(de)
|
1989-09-02 |
1991-03-07 |
Akzo Gmbh |
Cellulosische membranen
|
US5188934A
(en)
|
1989-11-14 |
1993-02-23 |
Applied Biosystems, Inc. |
4,7-dichlorofluorescein dyes as molecular probes
|
US5215882A
(en)
*
|
1989-11-30 |
1993-06-01 |
Ortho Diagnostic Systems, Inc. |
Method of immobilizing nucleic acid on a solid surface for use in nucleic acid hybridization assays
|
FR2659349B1
(fr)
|
1990-03-12 |
1993-12-24 |
Rhone Merieux |
Virus herpes recombinants notamment pour la realisation de vaccins, leur procede de preparation, les plasmides realises au cours de ce procede et les vaccins obtenus.
|
US5274113A
(en)
|
1991-11-01 |
1993-12-28 |
Molecular Probes, Inc. |
Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates
|
US5433896A
(en)
|
1994-05-20 |
1995-07-18 |
Molecular Probes, Inc. |
Dibenzopyrrometheneboron difluoride dyes
|
US5227487A
(en)
|
1990-04-16 |
1993-07-13 |
Molecular Probes, Inc. |
Certain tricyclic and pentacyclic-hetero nitrogen rhodol dyes
|
DE69032425T2
(de)
*
|
1990-05-11 |
1998-11-26 |
Microprobe Corp., Bothell, Wash. |
Teststreifen zum Eintauchen für Nukleinsäure-Hybridisierungsassays und Verfahren zur kovalenten Immobilisierung von Oligonucleotiden
|
US5248782A
(en)
|
1990-12-18 |
1993-09-28 |
Molecular Probes, Inc. |
Long wavelength heteroaryl-substituted dipyrrometheneboron difluoride dyes
|
US5187288A
(en)
|
1991-05-22 |
1993-02-16 |
Molecular Probes, Inc. |
Ethenyl-substituted dipyrrometheneboron difluoride dyes and their synthesis
|
US5300687A
(en)
|
1991-07-18 |
1994-04-05 |
Ortho Pharmaceutical Corporation |
Trifluoromethylbenzylphosphonates useful in treating osteoporosis
|
US5288625A
(en)
|
1991-09-13 |
1994-02-22 |
Biologic Research Center Of The Hungarian Academy Of Sciences |
Mammalian artificial chromosomes
|
US5632957A
(en)
|
1993-11-01 |
1997-05-27 |
Nanogen |
Molecular biological diagnostic systems including electrodes
|
US5846708A
(en)
|
1991-11-19 |
1998-12-08 |
Massachusetts Institiute Of Technology |
Optical and electrical methods and apparatus for molecule detection
|
US5324633A
(en)
|
1991-11-22 |
1994-06-28 |
Affymax Technologies N.V. |
Method and apparatus for measuring binding affinity
|
US5652099A
(en)
|
1992-02-12 |
1997-07-29 |
Conrad; Michael J. |
Probes comprising fluorescent nucleosides and uses thereof
|
JPH05236997A
(ja)
|
1992-02-28 |
1993-09-17 |
Hitachi Ltd |
ポリヌクレオチド捕捉用チップ
|
WO1993018186A1
(en)
*
|
1992-03-04 |
1993-09-16 |
The Regents Of The University Of California |
Comparative genomic hybridization (cgh)
|
US5976790A
(en)
*
|
1992-03-04 |
1999-11-02 |
The Regents Of The University Of California |
Comparative Genomic Hybridization (CGH)
|
US5981175A
(en)
|
1993-01-07 |
1999-11-09 |
Genpharm Internation, Inc. |
Methods for producing recombinant mammalian cells harboring a yeast artificial chromosome
|
EP0767361B1
(en)
|
1993-07-22 |
2000-02-23 |
Applied Spectral Imaging Ltd. |
Method and apparatus for spectral imaging
|
WO1995003400A1
(en)
|
1993-07-23 |
1995-02-02 |
Johns Hopkins University School Of Medicine |
Recombinationally targeted cloning in yeast artificial chromosomes
|
US6001982A
(en)
|
1993-07-29 |
1999-12-14 |
Isis Pharmaceuticals, Inc. |
Synthesis of oligonucleotides
|
US5637687A
(en)
*
|
1993-08-31 |
1997-06-10 |
Wiggins; James C. |
Methods and compositions for isolating nucleic acids
|
US5472842A
(en)
*
|
1993-10-06 |
1995-12-05 |
The Regents Of The University Of California |
Detection of amplified or deleted chromosomal regions
|
US6045996A
(en)
|
1993-10-26 |
2000-04-04 |
Affymetrix, Inc. |
Hybridization assays on oligonucleotide arrays
|
ATE214633T1
(de)
|
1993-10-28 |
2002-04-15 |
Houston Advanced Res Ct |
Mikrofabriziertes poröses durchflussgerät
|
US5965452A
(en)
|
1996-07-09 |
1999-10-12 |
Nanogen, Inc. |
Multiplexed active biologic array
|
US5610287A
(en)
*
|
1993-12-06 |
1997-03-11 |
Molecular Tool, Inc. |
Method for immobilizing nucleic acid molecules
|
US6028190A
(en)
|
1994-02-01 |
2000-02-22 |
The Regents Of The University Of California |
Probes labeled with energy transfer coupled dyes
|
US5578832A
(en)
|
1994-09-02 |
1996-11-26 |
Affymetrix, Inc. |
Method and apparatus for imaging a sample on a device
|
US5807522A
(en)
|
1994-06-17 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for fabricating microarrays of biological samples
|
US5554744A
(en)
*
|
1994-09-23 |
1996-09-10 |
Hybridon, Inc. |
Method for loading solid supports for nucleic acid synthesis
|
US5556752A
(en)
|
1994-10-24 |
1996-09-17 |
Affymetrix, Inc. |
Surface-bound, unimolecular, double-stranded DNA
|
US5830645A
(en)
*
|
1994-12-09 |
1998-11-03 |
The Regents Of The University Of California |
Comparative fluorescence hybridization to nucleic acid arrays
|
US5601982A
(en)
*
|
1995-02-07 |
1997-02-11 |
Sargent; Jeannine P. |
Method and apparatus for determining the sequence of polynucleotides
|
US5959098A
(en)
|
1996-04-17 |
1999-09-28 |
Affymetrix, Inc. |
Substrate preparation process
|
US5635351A
(en)
|
1995-03-14 |
1997-06-03 |
The Regents Of The University Of California |
Genetic gain and loss in gliomas
|
US5863504A
(en)
|
1995-03-16 |
1999-01-26 |
Bio-Rad Laboratories, Inc. |
Fluorescence imaging instrument utilizing fish
|
US5962674A
(en)
|
1995-06-01 |
1999-10-05 |
Hybridon, Inc. |
Synthesis of oligonucleotides containing alkylphosphonate internucleoside linkages
|
US5614386A
(en)
|
1995-06-23 |
1997-03-25 |
Baylor College Of Medicine |
Alternative dye-labeled primers for automated DNA sequencing
|
US5856174A
(en)
|
1995-06-29 |
1999-01-05 |
Affymetrix, Inc. |
Integrated nucleic acid diagnostic device
|
FR2736342B1
(fr)
|
1995-07-07 |
1999-01-29 |
Univ Claude Bernard Lyon |
Procede pour la fabrication d'aerogels de silice monolithiques et aerogels de silice ainsi obtenus
|
US5630932A
(en)
*
|
1995-09-06 |
1997-05-20 |
Molecular Imaging Corporation |
Tip etching system and method for etching platinum-containing wire
|
US5734041A
(en)
|
1995-10-20 |
1998-03-31 |
Mcgill University |
Preparation of chiral phosphorothioate oligomers
|
US5721118A
(en)
|
1995-10-31 |
1998-02-24 |
The Regents Of The University Of California, San Diego |
Mammalian artificial chromosomes and methods of using same
|
US6022963A
(en)
|
1995-12-15 |
2000-02-08 |
Affymetrix, Inc. |
Synthesis of oligonucleotide arrays using photocleavable protecting groups
|
US5714386A
(en)
|
1996-01-11 |
1998-02-03 |
Board Of Trustees Of The Leland Stanford Junior University |
Cy7-allophycocyanin conjugates for use in multiplex fluorescence detection assays
|
EP0880598A4
(en)
*
|
1996-01-23 |
2005-02-23 |
Affymetrix Inc |
RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
|
US6013440A
(en)
|
1996-03-11 |
2000-01-11 |
Affymetrix, Inc. |
Nucleic acid affinity columns
|
US6025155A
(en)
|
1996-04-10 |
2000-02-15 |
Chromos Molecular Systems, Inc. |
Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
|
US5880473A
(en)
|
1997-07-28 |
1999-03-09 |
Applied Imaging, Inc. |
Multifluor-fluorescence in-situ hybridization (M-FISH) imaging techniques using multiple multiband filters with image registration
|
US6027709A
(en)
|
1997-01-10 |
2000-02-22 |
Li-Cor Inc. |
Fluorescent cyanine dyes
|
US5790727A
(en)
|
1997-02-05 |
1998-08-04 |
Brookhaven Science Associates Llc |
Laser illumination of multiple capillaries that form a waveguide
|
US6048457A
(en)
|
1997-02-26 |
2000-04-11 |
Millipore Corporation |
Cast membrane structures for sample preparation
|
US5919626A
(en)
*
|
1997-06-06 |
1999-07-06 |
Orchid Bio Computer, Inc. |
Attachment of unmodified nucleic acids to silanized solid phase surfaces
|
US5939261A
(en)
|
1997-06-24 |
1999-08-17 |
Sarnoff Corporation |
Method for capturing a nucleic acid
|
US5914039A
(en)
|
1997-07-01 |
1999-06-22 |
Zenon Environmental Inc. |
Filtration membrane with calcined α-alumina particles therein
|
US5943129A
(en)
|
1997-08-07 |
1999-08-24 |
Cambridge Research & Instrumentation Inc. |
Fluorescence imaging system
|
US6049380A
(en)
|
1997-11-12 |
2000-04-11 |
Regents Of The University Of California |
Single molecule identification using selected fluorescence characteristics
|
US5922617A
(en)
|
1997-11-12 |
1999-07-13 |
Functional Genetics, Inc. |
Rapid screening assay methods and devices
|
US5874259A
(en)
|
1997-11-21 |
1999-02-23 |
Wisconsin Alumni Research Foundation |
Conditionally amplifiable BAC vector
|
US6077673A
(en)
*
|
1998-03-31 |
2000-06-20 |
Clontech Laboratories, Inc. |
Mouse arrays and kits comprising the same
|
US6048695A
(en)
|
1998-05-04 |
2000-04-11 |
Baylor College Of Medicine |
Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
|
US6251601B1
(en)
*
|
1999-02-02 |
2001-06-26 |
Vysis, Inc. |
Simultaneous measurement of gene expression and genomic abnormalities using nucleic acid microarrays
|
DK1132739T3
(da)
*
|
2000-05-16 |
2002-01-28 |
Biochip Technologies Gmbh |
Linkersystem til aktivering af overflader til biokonjugation og fremgangsmåder til anvendelse deraf
|
JP4502167B2
(ja)
*
|
2001-07-06 |
2010-07-14 |
大日本印刷株式会社 |
マイクロアレイチップ
|