JP2005518367A5 - - Google Patents
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- JP2005518367A5 JP2005518367A5 JP2003548873A JP2003548873A JP2005518367A5 JP 2005518367 A5 JP2005518367 A5 JP 2005518367A5 JP 2003548873 A JP2003548873 A JP 2003548873A JP 2003548873 A JP2003548873 A JP 2003548873A JP 2005518367 A5 JP2005518367 A5 JP 2005518367A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- polypeptide antigen
- individual
- composition
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 105
- 239000000427 antigen Substances 0.000 claims 99
- 102000036639 antigens Human genes 0.000 claims 98
- 108091007433 antigens Proteins 0.000 claims 98
- 102000004196 processed proteins & peptides Human genes 0.000 claims 82
- 229920001184 polypeptide Polymers 0.000 claims 77
- 239000000203 mixture Substances 0.000 claims 56
- 210000001744 T-lymphocyte Anatomy 0.000 claims 28
- 239000003814 drug Substances 0.000 claims 25
- 239000003795 chemical substances by application Substances 0.000 claims 23
- 229940079593 drug Drugs 0.000 claims 15
- 239000013566 allergen Substances 0.000 claims 12
- 230000001225 therapeutic effect Effects 0.000 claims 5
- 239000002243 precursor Substances 0.000 claims 4
- 238000011260 co-administration Methods 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 241000255789 Bombyx mori Species 0.000 claims 2
- 241000282472 Canis lupus familiaris Species 0.000 claims 2
- -1 Der p 9 Proteins 0.000 claims 2
- 241000282326 Felis catus Species 0.000 claims 2
- 241000233866 Fungi Species 0.000 claims 2
- 108091022930 Glutamate decarboxylase Proteins 0.000 claims 2
- 102000008214 Glutamate decarboxylase Human genes 0.000 claims 2
- 102000002812 Heat-Shock Proteins Human genes 0.000 claims 2
- 108010004889 Heat-Shock Proteins Proteins 0.000 claims 2
- 102000002233 Myelin-Oligodendrocyte Glycoprotein Human genes 0.000 claims 2
- 108010000123 Myelin-Oligodendrocyte Glycoprotein Proteins 0.000 claims 2
- 241001494479 Pecora Species 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- KISWVXRQTGLFGD-UHFFFAOYSA-N 2-[[2-[[6-amino-2-[[2-[[2-[[5-amino-2-[[2-[[1-[2-[[6-amino-2-[(2,5-diamino-5-oxopentanoyl)amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)p Chemical compound C1CCN(C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(N)CCC(N)=O)C1C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(CCCN=C(N)N)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CC(C)C)C(O)=O)CC1=CC=C(O)C=C1 KISWVXRQTGLFGD-UHFFFAOYSA-N 0.000 claims 1
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 241000238876 Acari Species 0.000 claims 1
- 244000036975 Ambrosia artemisiifolia Species 0.000 claims 1
- 235000003129 Ambrosia artemisiifolia var elatior Nutrition 0.000 claims 1
- 241000256837 Apidae Species 0.000 claims 1
- 241000239290 Araneae Species 0.000 claims 1
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 208000009137 Behcet syndrome Diseases 0.000 claims 1
- 241000283690 Bos taurus Species 0.000 claims 1
- 241000257161 Calliphoridae Species 0.000 claims 1
- 244000025254 Cannabis sativa Species 0.000 claims 1
- 241000700198 Cavia Species 0.000 claims 1
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 claims 1
- 108010009685 Cholinergic Receptors Proteins 0.000 claims 1
- 208000015943 Coeliac disease Diseases 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 108010055622 Dermatophagoides farinae antigen f 1 Proteins 0.000 claims 1
- 108010082995 Dermatophagoides farinae antigen f 2 Proteins 0.000 claims 1
- 108010082996 Dermatophagoides farinae antigen f 4 Proteins 0.000 claims 1
- 108010082990 Dermatophagoides farinae antigen f 7 Proteins 0.000 claims 1
- 108010061629 Dermatophagoides pteronyssinus antigen p 1 Proteins 0.000 claims 1
- 108010061608 Dermatophagoides pteronyssinus antigen p 2 Proteins 0.000 claims 1
- 108010061612 Dermatophagoides pteronyssinus antigen p 3 Proteins 0.000 claims 1
- 108010061569 Dermatophagoides pteronyssinus antigen p 4 Proteins 0.000 claims 1
- 108010061573 Dermatophagoides pteronyssinus antigen p 5 Proteins 0.000 claims 1
- 108010061636 Dermatophagoides pteronyssinus antigen p 6 Proteins 0.000 claims 1
- 108010061638 Dermatophagoides pteronyssinus antigen p 7 Proteins 0.000 claims 1
- 241000255925 Diptera Species 0.000 claims 1
- 241000196324 Embryophyta Species 0.000 claims 1
- 241000283086 Equidae Species 0.000 claims 1
- 241000282324 Felis Species 0.000 claims 1
- 241000699694 Gerbillinae Species 0.000 claims 1
- 108010061711 Gliadin Proteins 0.000 claims 1
- 108010014597 HLA-B44 Antigen Proteins 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 102100039869 Histone H2B type F-S Human genes 0.000 claims 1
- 101001035372 Homo sapiens Histone H2B type F-S Proteins 0.000 claims 1
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 claims 1
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 claims 1
- 102000004877 Insulin Human genes 0.000 claims 1
- 108090001061 Insulin Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 241000699670 Mus sp. Species 0.000 claims 1
- 241000257226 Muscidae Species 0.000 claims 1
- 101000944608 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) Chaperonin GroEL 2 Proteins 0.000 claims 1
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 241000209504 Poaceae Species 0.000 claims 1
- 102000001708 Protein Isoforms Human genes 0.000 claims 1
- 108010029485 Protein Isoforms Proteins 0.000 claims 1
- 102000016202 Proteolipids Human genes 0.000 claims 1
- 108010010974 Proteolipids Proteins 0.000 claims 1
- 241000700159 Rattus Species 0.000 claims 1
- 108010003581 Ribulose-bisphosphate carboxylase Proteins 0.000 claims 1
- 102000007562 Serum Albumin Human genes 0.000 claims 1
- 108010071390 Serum Albumin Proteins 0.000 claims 1
- 241000282887 Suidae Species 0.000 claims 1
- 101710137302 Surface antigen S Proteins 0.000 claims 1
- 241000255588 Tephritidae Species 0.000 claims 1
- 102000009843 Thyroglobulin Human genes 0.000 claims 1
- 108010034949 Thyroglobulin Proteins 0.000 claims 1
- 241000256856 Vespidae Species 0.000 claims 1
- 102000034337 acetylcholine receptors Human genes 0.000 claims 1
- 230000000172 allergic effect Effects 0.000 claims 1
- 235000003484 annual ragweed Nutrition 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 235000006263 bur ragweed Nutrition 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 235000003488 common ragweed Nutrition 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 239000000428 dust Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 239000013568 food allergen Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 229940125396 insulin Drugs 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007913 intrathecal administration Methods 0.000 claims 1
- 238000010253 intravenous injection Methods 0.000 claims 1
- 239000004816 latex Substances 0.000 claims 1
- 229920000126 latex Polymers 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 206010028417 myasthenia gravis Diseases 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000013573 pollen allergen Substances 0.000 claims 1
- 235000009736 ragweed Nutrition 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
- 229960002175 thyroglobulin Drugs 0.000 claims 1
- 206010043778 thyroiditis Diseases 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33838501P | 2001-12-05 | 2001-12-05 | |
| US60/338,385 | 2001-12-05 | ||
| PCT/GB2002/005548 WO2003047618A2 (en) | 2001-12-05 | 2002-12-05 | Immunotherapeutic methods and systems |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009215825A Division JP2009292838A (ja) | 2001-12-05 | 2009-09-17 | 免疫療法および系 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005518367A JP2005518367A (ja) | 2005-06-23 |
| JP2005518367A5 true JP2005518367A5 (cg-RX-API-DMAC7.html) | 2006-02-02 |
| JP4874522B2 JP4874522B2 (ja) | 2012-02-15 |
Family
ID=23324613
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003548873A Expired - Fee Related JP4874522B2 (ja) | 2001-12-05 | 2002-12-05 | 免疫療法および系 |
| JP2009215825A Pending JP2009292838A (ja) | 2001-12-05 | 2009-09-17 | 免疫療法および系 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009215825A Pending JP2009292838A (ja) | 2001-12-05 | 2009-09-17 | 免疫療法および系 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20060024334A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1453539B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP4874522B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE414534T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002347369A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2469078A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60229979D1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2316632T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003047618A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60229979D1 (cg-RX-API-DMAC7.html) * | 2001-12-05 | 2009-01-02 | Circassia Ltd | |
| US7279295B2 (en) * | 2002-03-27 | 2007-10-09 | Phadia Ab | Allergen |
| CA2486112A1 (en) * | 2002-05-16 | 2003-11-27 | Alk Abello A/S | Allergen mutants |
| GB0307989D0 (en) * | 2003-04-07 | 2003-05-14 | Mcewen Lab Ltd | Therapeutic composition |
| CN1852701A (zh) * | 2003-09-17 | 2006-10-25 | 婴儿保健公司 | 防止过敏的方法及装置 |
| DE10351471A1 (de) * | 2003-11-04 | 2005-06-09 | Ursula Prof. Dr. Wiedermann-Schmidt | Polyvalente Allergievakzine |
| US20050287068A1 (en) * | 2004-06-17 | 2005-12-29 | Bot Adrian I | Efficacy of active immunotherapy by integrating diagnostic with therapeutic methods |
| CN100374152C (zh) | 2005-12-23 | 2008-03-12 | 中国农业大学 | 一种过敏性反应抑制剂 |
| JP2007189920A (ja) * | 2006-01-17 | 2007-08-02 | Osaka Prefecture Univ | イヌアレルギーに対する予防又は治療作用を有するポリペプチド |
| JP2007189919A (ja) * | 2006-01-17 | 2007-08-02 | Osaka Prefecture Univ | イヌアレルギーに対する予防又は治療作用を有するポリペプチド |
| BRPI0807133A2 (pt) * | 2007-01-30 | 2014-04-15 | Alk Abello As | Uso de um primeiro alérgeno do grupo 2 de ácaro da poeira domiciliar para tratar alergia a um segundo alérgeno do grupo 2 de ácaro da poeira domiciliar |
| EP2450372B1 (en) | 2007-01-30 | 2015-04-22 | Epivax, Inc. | Regulatory T cell epitopes, compositions and uses thereof |
| GB0710529D0 (en) * | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| AU2013202871B2 (en) * | 2007-06-01 | 2015-10-22 | Circassia Limited | Vaccine peptide combinations against cat allergy |
| WO2009022155A2 (en) | 2007-08-15 | 2009-02-19 | Circassia Limited | Peptide with reduced dimer formation |
| US8821887B2 (en) * | 2008-08-15 | 2014-09-02 | Circassia Limited | T-cell antigen peptide from allergen for stimulation of IL-10 production |
| DK2153841T4 (en) | 2008-08-15 | 2016-02-15 | Circassia Ltd | Vaccine comprising Amb a 1 peptides for use in the treatment of ambrosieallergi |
| GB0821806D0 (en) * | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
| CN102438643B (zh) | 2008-11-30 | 2015-07-01 | 免疫桑特公司 | 用于治疗乳糜泻的组合物和方法 |
| BRPI1008802A2 (pt) | 2009-02-05 | 2016-03-08 | Circassia Ltd | composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição |
| GB201002559D0 (en) | 2010-02-15 | 2010-03-31 | Circassia Ltd | Birch peptides for vaccine |
| WO2011106645A1 (en) * | 2010-02-26 | 2011-09-01 | Benaroya Research Institute | Direct analysis of antigen-specific immune response |
| WO2011112788A1 (en) * | 2010-03-12 | 2011-09-15 | Antigen Laboratories, Inc. | Methods of treating allergies with substantially phenol-free carriers |
| EP3524259B1 (en) * | 2010-04-30 | 2021-10-13 | Allovate, LLC | Oral strip for allergic desensitization via the vestibular mucosal surface |
| EP2681555B1 (en) | 2011-02-25 | 2020-04-08 | Benaroya Research Institute | Detection of an allergic disorder |
| CA2777431A1 (en) * | 2011-05-20 | 2012-11-20 | Nitto Denko Corporation | Pharmaceutical composition and method for producing the same |
| US11421006B2 (en) | 2012-05-03 | 2022-08-23 | La Jolla Institute For Allergy And Immunology | T cell epitopes from Cockroach and methods of making and using same |
| GB201208293D0 (en) * | 2012-05-11 | 2012-06-20 | Circassia Ltd | Hydrochlorice salt of peptide |
| DK2914286T3 (da) | 2012-10-30 | 2021-11-08 | Aravax Pty Ltd | Hidtil ukendte immunterapeutiske molekyler og anvendelser deraf |
| JP2014028820A (ja) * | 2013-08-30 | 2014-02-13 | China Agricultural Univ | アレルギー抑制剤の組成物及びキットならびにその使用方法 |
| EP3043812A1 (en) | 2013-09-10 | 2016-07-20 | Immusant Inc. | Dosage of a gluten peptide composition |
| JP2016537299A (ja) | 2013-09-19 | 2016-12-01 | アロヴェイト・エルエルシー | 口腔粘膜にアレルゲンを供給するための練り歯磨き |
| JP7007534B2 (ja) | 2013-09-25 | 2022-01-24 | アラヴァックス ピーティーワイ リミテッド | 新規免疫療法組成物およびその使用 |
| EA034620B1 (ru) * | 2014-03-18 | 2020-02-27 | Апептико Форшунг Унд Энтвиклунг Гмбх | Пептидный медикамент в виде сухого порошка |
| US10872313B2 (en) | 2015-06-02 | 2020-12-22 | ROCA Medical Ltd. | Method for repurposing NDC codes in a pharmaceutical database for venom derived allergens involved in venom immunotherapy |
| AU2015323979A1 (en) | 2014-09-29 | 2017-05-18 | Immusant, Inc. | Use of HLA genetic status to assess or select treatment of celiac disease |
| US10548974B2 (en) | 2015-06-02 | 2020-02-04 | ROCA Medical Ltd. | Therapeutic treatment kit for allergies based on DNA profiles |
| US20160362205A1 (en) * | 2015-06-02 | 2016-12-15 | ROCA Medical Ltd. | Use of autoinjector for distributing antigens to the public |
| US10369215B2 (en) | 2015-06-02 | 2019-08-06 | ROCA Medical Ltd. | Predilution sets for distributing antigens |
| US20170021010A1 (en) * | 2015-07-21 | 2017-01-26 | David Phillip ERSTEIN | Allergy preventing dosage controlled food packets |
| KR102797285B1 (ko) * | 2016-03-03 | 2025-04-18 | 호유 가부시키가이샤 | 대두 알레르기의 항원 |
| CN108265059B (zh) * | 2016-12-31 | 2021-01-05 | 江苏众红生物工程创药研究院有限公司 | 一种重组粉尘螨2类变应原蛋白及其制备方法与应用 |
| CN108265057B (zh) * | 2016-12-31 | 2019-10-18 | 江苏众红生物工程创药研究院有限公司 | 一种重组户尘螨2类变应原蛋白及其制备方法和应用 |
| JP7555788B2 (ja) * | 2020-10-30 | 2024-09-25 | アサヒグループホールディングス株式会社 | タンパク質の起源種判別方法 |
| CN113336862B (zh) * | 2021-07-05 | 2022-03-01 | 广东省科学院动物研究所 | 一种抗多发性硬化的重组蛋白及其制备方法和用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5358710A (en) * | 1989-12-01 | 1994-10-25 | Alec Sehon | Method for the suppression of an immune response |
| WO1994024281A1 (en) * | 1993-04-14 | 1994-10-27 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| AU2238395A (en) * | 1994-04-01 | 1995-10-23 | Immulogic Pharmaceutical Corporation | Haptenated peptides and uses thereof |
| EP1044019A1 (en) * | 1998-01-09 | 2000-10-18 | Circassia Limited | Methods and compositions for desensitisation |
| DE60229979D1 (cg-RX-API-DMAC7.html) * | 2001-12-05 | 2009-01-02 | Circassia Ltd |
-
2002
- 2002-12-05 DE DE60229979T patent/DE60229979D1/de not_active Expired - Lifetime
- 2002-12-05 EP EP02783303A patent/EP1453539B1/en not_active Revoked
- 2002-12-05 JP JP2003548873A patent/JP4874522B2/ja not_active Expired - Fee Related
- 2002-12-05 AT AT02783303T patent/ATE414534T1/de not_active IP Right Cessation
- 2002-12-05 WO PCT/GB2002/005548 patent/WO2003047618A2/en not_active Ceased
- 2002-12-05 CA CA002469078A patent/CA2469078A1/en not_active Abandoned
- 2002-12-05 ES ES02783303T patent/ES2316632T3/es not_active Expired - Lifetime
- 2002-12-05 AU AU2002347369A patent/AU2002347369A1/en not_active Abandoned
- 2002-12-05 US US10/498,026 patent/US20060024334A1/en not_active Abandoned
-
2009
- 2009-09-17 JP JP2009215825A patent/JP2009292838A/ja active Pending
-
2010
- 2010-08-20 US US12/860,216 patent/US20110142867A1/en not_active Abandoned
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| Lin | Subcutaneous Immunotherapy for Allergic Rhinitis and Asthma | |
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