JP2005517899A5 - - Google Patents
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- Publication number
- JP2005517899A5 JP2005517899A5 JP2003546110A JP2003546110A JP2005517899A5 JP 2005517899 A5 JP2005517899 A5 JP 2005517899A5 JP 2003546110 A JP2003546110 A JP 2003546110A JP 2003546110 A JP2003546110 A JP 2003546110A JP 2005517899 A5 JP2005517899 A5 JP 2005517899A5
- Authority
- JP
- Japan
- Prior art keywords
- ligand
- biotin
- compound
- electin
- hapten
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000027455 binding Effects 0.000 claims 4
- 239000003446 ligand Substances 0.000 claims 3
- 229960002685 biotin Drugs 0.000 claims 2
- 235000020958 biotin Nutrition 0.000 claims 2
- 239000011616 biotin Substances 0.000 claims 2
- 229920000160 (ribonucleotides)n+m Polymers 0.000 claims 1
- 108090001008 Avidin Proteins 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 229940088597 Hormone Drugs 0.000 claims 1
- 102000004895 Lipoproteins Human genes 0.000 claims 1
- 108090001030 Lipoproteins Proteins 0.000 claims 1
- 108010090804 Streptavidin Proteins 0.000 claims 1
- 102000004965 antibodies Human genes 0.000 claims 1
- 108090001123 antibodies Proteins 0.000 claims 1
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 1
- -1 biotin compound Chemical class 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 235000014633 carbohydrates Nutrition 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 229920003013 deoxyribonucleic acid Polymers 0.000 claims 1
- 150000002016 disaccharides Chemical class 0.000 claims 1
- 150000004676 glycans Polymers 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 239000006249 magnetic particle Substances 0.000 claims 1
- 239000002207 metabolite Substances 0.000 claims 1
- 150000002772 monosaccharides Chemical class 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229920001542 oligosaccharide Polymers 0.000 claims 1
- 150000002482 oligosaccharides Polymers 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 150000004804 polysaccharides Polymers 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
Claims (4)
- コロイド状磁気粒子におけるサイズが5と10,000nmとの間、そしてより好ましくは100と500nmとの間であることを特徴とする請求項1乃至3のいずれか1項記載の方法。
- そのリガンドは、(ポリ)カルボハイドレイト/エレクチン、ビオチン又はビオチン化合物/アビジン又はストレプトアビジン、タンパク質受容体及びその特定リガンド、及びハプテン/抗体などの結合対の双方の一方から選択されることを特徴とする請求項6記載の方法。
- 固定されたリガンドが、ペプチド、糖タンパク質、リポタンパク質及び他の類似物を遊離又は複合形状で含むタンパク質、DNA又はRNA及びこれらの相同体などの核酸、単糖又は2糖、オリゴ糖、および多糖などの糖類、脂質、ホルモン、受容体、代謝産物又は他の生物的な物質から選択された化合物であることを特徴とする請求項1乃至7のいずれか1項記載の方法。
- 本標識が、視覚化し、光学的に機械的又は電気的に特徴付けできることを特徴とする請求項14記載の方法。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0115011A FR2832507B1 (fr) | 2001-11-20 | 2001-11-20 | Methode de detection d'analyte(s) a l'aide de particules magnetiques colloidales |
| PCT/FR2002/003974 WO2003044532A1 (fr) | 2001-11-20 | 2002-11-20 | Methode de detection d'analyte(s) a l'aide de particules magnetiques colloidales |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005517899A JP2005517899A (ja) | 2005-06-16 |
| JP2005517899A5 true JP2005517899A5 (ja) | 2006-01-05 |
Family
ID=8869592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003546110A Pending JP2005517899A (ja) | 2001-11-20 | 2002-11-20 | コロイド状磁気粒子を使用した分析物の検出方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7332353B2 (ja) |
| EP (1) | EP1446666B1 (ja) |
| JP (1) | JP2005517899A (ja) |
| KR (1) | KR20050044559A (ja) |
| CN (1) | CN100501403C (ja) |
| AT (1) | ATE431553T1 (ja) |
| AU (1) | AU2002361324A1 (ja) |
| BR (1) | BR0214233A (ja) |
| CA (1) | CA2467050A1 (ja) |
| DE (1) | DE60232353D1 (ja) |
| ES (1) | ES2325917T3 (ja) |
| FR (1) | FR2832507B1 (ja) |
| HU (1) | HU225636B1 (ja) |
| MX (1) | MXPA04004679A (ja) |
| NO (1) | NO20042579L (ja) |
| PL (1) | PL368690A1 (ja) |
| RU (1) | RU2004118490A (ja) |
| WO (1) | WO2003044532A1 (ja) |
| ZA (1) | ZA200403903B (ja) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2878960A1 (fr) * | 2004-12-08 | 2006-06-09 | Centre Nat Rech Scient | Procede pour mettre en oeuvre un test d'agglutination dans un microcanal |
| US9733315B2 (en) * | 2005-07-27 | 2017-08-15 | University Of Houston | Nanomagnetic detector array for biomolecular recognition |
| CA2620861C (en) | 2005-08-31 | 2016-07-05 | T2 Biosystems, Inc. | Nmr device for detection of analytes |
| US8586389B2 (en) * | 2005-09-28 | 2013-11-19 | Kent State University | Ligand concentrating, liquid crystal biosensor system |
| US8084270B2 (en) | 2006-01-25 | 2011-12-27 | Koninklijke Philips Electronics N.V. | Device for analyzing fluids |
| KR100738496B1 (ko) * | 2006-07-27 | 2007-07-11 | 한양대학교 산학협력단 | 자성 미세입자 및 배향성 고정화 리간드를 이용한 항체단백질 분리방법 |
| EP2084550A1 (en) * | 2006-11-08 | 2009-08-05 | T2 Biosystems, Inc. | Nmr systems for in vivo detection of analytes |
| KR100823684B1 (ko) | 2006-12-06 | 2008-04-21 | 한국전자통신연구원 | 바코드 ｄｎａ를 이용한 생물학적 표적 물질의 검출 방법 |
| FR2919390B1 (fr) | 2007-07-27 | 2009-10-30 | Bertin Technologies Soc Par Ac | Procede de dosage d'un analyte dans un milieu liquide |
| CA2704674A1 (en) | 2007-11-06 | 2009-05-14 | T2 Biosystems, Inc. | Small magnet and rf coil for magnetic resonance relaxometry |
| EP2246702B1 (en) * | 2007-12-03 | 2015-10-07 | Tamagawa Seiki Co., Ltd. | Biosensing method using coated magnetic microparticles and biosensing device to be used in the method |
| FR2928656B1 (fr) * | 2008-03-14 | 2011-08-26 | Biomerieux Sa | Procede de detection en temps reel de microorganismes dans un milieu de culture liquide par agglutination. |
| US9157974B2 (en) | 2008-10-29 | 2015-10-13 | T2 Biosystems, Inc. | NMR detection of coagulation time |
| EP2492665A1 (en) * | 2009-10-19 | 2012-08-29 | Tokyo Institute of Technology | Biosensor using magnetic microparticles |
| US9023607B2 (en) * | 2010-04-26 | 2015-05-05 | Intellectual Discovery Co., Ltd. | Method for early diagnosis of alzheimer'S disease using phototransistor |
| FR2959820B1 (fr) * | 2010-05-10 | 2013-03-15 | Bertin Technologies Sa | Procede de dosage d'un analyte dans un milieu liquide |
| WO2012054638A2 (en) | 2010-10-22 | 2012-04-26 | T2 Biosystems, Inc. | Nmr systems and methods for the detection of analytes |
| US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| US8409807B2 (en) | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| EP2541250A1 (en) | 2011-06-30 | 2013-01-02 | Koninklijke Philips Electronics N.V. | Molecular architecture on magnetic particles for affinity assays with low non-specific binding |
| EP2732046B1 (en) | 2011-07-13 | 2017-09-06 | T2 Biosystems, Inc. | Nmr methods for monitoring blood clot formation |
| EP2748651B1 (en) | 2011-09-21 | 2017-08-30 | T2 Biosystems, Inc. | Nmr methods for endotoxin analysis |
| DE102011089798B4 (de) | 2011-12-23 | 2021-06-10 | Biophysical Tools GmbH | Massiv paralleler Test molekularer Wechselwirkungen basierend auf magnetischen Nano- und Mikropartikeln |
| FR2986617B1 (fr) * | 2012-02-02 | 2015-03-27 | Horiba Abx Sas | Dispositif et procede pour effectuer des mesures hematologiques et biochimiques a partir d'un echantillon biologique |
| US9562271B2 (en) | 2012-04-20 | 2017-02-07 | T2 Biosystems, Inc. | Compositions and methods for detection of Candida species |
| EP2929047A4 (en) | 2012-12-07 | 2016-08-03 | T2 Biosystems Inc | METHOD FOR MONITORING THE FORMING OF SEALED GERINNSELN |
| CN108697141A (zh) * | 2015-12-29 | 2018-10-23 | N·V·努特里奇亚 | 含有不可消化寡糖和非复制型产乳酸细菌的营养配方物 |
| AU2017210033B2 (en) | 2016-01-21 | 2022-09-29 | T2 Biosystems, Inc. | NMR methods and systems for the rapid detection of bacteria |
| US11585882B2 (en) * | 2018-04-11 | 2023-02-21 | Mars Sciences Limited | Superparamagnetic particle imaging and its applications in quantitative multiplex stationary phase diagnostic assays |
| ES2827176T3 (es) * | 2018-05-30 | 2021-05-20 | Pragmatic Diagnostics S L | Procedimiento optomagnetoforético de detección de sustancias biológicas y químicas |
| AU2019306640B2 (en) * | 2018-07-19 | 2022-09-22 | Beckman Coulter, Inc. | Magnetic particles |
| WO2022189819A1 (en) | 2021-03-09 | 2022-09-15 | Etablissement Francais Du Sang | Detection of infectious agent based on recombinase polymerase amplification combined with a magnetic field-enhanced agglutination |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK140815B (da) * | 1975-06-10 | 1979-11-19 | Weeke Bengt | Fremgangsmåde til påvisning eller bestemmelse af antistoffer i legemsvæsker ved hjælp af kendte antigener eller til bestemmelse af antigener ved hjælp af kendte antistoffer fra legemsvæsker samt et middel til anvendelse ved udøvelse af fremgangsmåden. |
| US4554088A (en) * | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
| US4622298A (en) * | 1984-08-09 | 1986-11-11 | Becton, Dickinson And Company | Detection and quantitation of microorganisms, leukocytes and squamous epithelial cells in urine |
| US5512332A (en) * | 1985-10-04 | 1996-04-30 | Immunivest Corporation | Process of making resuspendable coated magnetic particles |
| US5639620A (en) * | 1990-10-31 | 1997-06-17 | Coulter Corporation | Polymeric particles having a biodegradable gelatin or aminodextran coating and process for making same |
| US5637469A (en) * | 1992-05-01 | 1997-06-10 | Trustees Of The University Of Pennsylvania | Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems |
| WO1994009368A1 (en) * | 1992-10-15 | 1994-04-28 | Coulter Corporation | Particles having gelatin-aminodextran coatings of and processes for making same |
| US5298741A (en) * | 1993-01-13 | 1994-03-29 | Trustees Of Tufts College | Thin film fiber optic sensor array and apparatus for concurrent viewing and chemical sensing of a sample |
| GB9524393D0 (en) * | 1995-11-29 | 1996-01-31 | Mini Agriculture & Fisheries | Extraction and labelling of materials |
| US5817458A (en) * | 1996-10-15 | 1998-10-06 | The Avriel Group, Amcas Division Inc. | Reagent system for detecting HIV-infected peripheral blood lymphocytes in whole blood |
| WO1998016101A1 (en) * | 1996-10-15 | 1998-04-23 | Bio-Tech Imaging, Inc. | Reagent system and kit for detecting hiv infected cells |
| WO1998051435A1 (en) * | 1997-05-14 | 1998-11-19 | Weixin Tang | Fully-coated, uniform-sized metallic particles |
| DE19822123C2 (de) * | 1997-11-21 | 2003-02-06 | Meinhard Knoll | Verfahren und Vorrichtung zum Nachweis von Analyten |
| CA2312102C (en) * | 1997-12-24 | 2007-09-04 | Cepheid | Integrated fluid manipulation cartridge |
| DE69907630T2 (de) * | 1998-01-22 | 2004-02-26 | Luminex Corp., Austin | Mikropartikel mit multiplen fluoreszenz-signalen |
-
2001
- 2001-11-20 FR FR0115011A patent/FR2832507B1/fr not_active Expired - Fee Related
-
2002
- 2002-11-20 KR KR1020047007733A patent/KR20050044559A/ko not_active Application Discontinuation
- 2002-11-20 BR BR0214233-3A patent/BR0214233A/pt not_active IP Right Cessation
- 2002-11-20 PL PL02368690A patent/PL368690A1/xx not_active Application Discontinuation
- 2002-11-20 CN CNB028230337A patent/CN100501403C/zh not_active Expired - Fee Related
- 2002-11-20 AU AU2002361324A patent/AU2002361324A1/en not_active Abandoned
- 2002-11-20 US US10/496,114 patent/US7332353B2/en not_active Expired - Fee Related
- 2002-11-20 WO PCT/FR2002/003974 patent/WO2003044532A1/fr active Application Filing
- 2002-11-20 JP JP2003546110A patent/JP2005517899A/ja active Pending
- 2002-11-20 CA CA002467050A patent/CA2467050A1/fr not_active Abandoned
- 2002-11-20 AT AT02796851T patent/ATE431553T1/de not_active IP Right Cessation
- 2002-11-20 RU RU2004118490/15A patent/RU2004118490A/ru not_active Application Discontinuation
- 2002-11-20 HU HU0402276A patent/HU225636B1/hu not_active IP Right Cessation
- 2002-11-20 ES ES02796851T patent/ES2325917T3/es not_active Expired - Lifetime
- 2002-11-20 EP EP02796851A patent/EP1446666B1/fr not_active Expired - Lifetime
- 2002-11-20 MX MXPA04004679A patent/MXPA04004679A/es not_active Application Discontinuation
- 2002-11-20 DE DE60232353T patent/DE60232353D1/de not_active Expired - Lifetime
-
2004
- 2004-05-20 ZA ZA200403903A patent/ZA200403903B/en unknown
- 2004-06-18 NO NO20042579A patent/NO20042579L/no not_active Application Discontinuation
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