JP2005512979A5 - - Google Patents
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- Publication number
- JP2005512979A5 JP2005512979A5 JP2003538188A JP2003538188A JP2005512979A5 JP 2005512979 A5 JP2005512979 A5 JP 2005512979A5 JP 2003538188 A JP2003538188 A JP 2003538188A JP 2003538188 A JP2003538188 A JP 2003538188A JP 2005512979 A5 JP2005512979 A5 JP 2005512979A5
- Authority
- JP
- Japan
- Prior art keywords
- kdi
- tripeptide
- pharmaceutical composition
- spinal cord
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 208000008513 Spinal Cord Injury Diseases 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 206010022114 Injury Diseases 0.000 claims 1
- 206010011302 Peripheral nerve injury Diseases 0.000 claims 1
- 210000000278 Spinal Cord Anatomy 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
Claims (12)
- 薬剤用のトリペプチド配列ＫＤＩ（リジン−アスパラギン酸−イソロイシン）。
- 損傷または変性した神経の修復用のトリペプチド配列ＫＤＩ。
- 中枢神経または末梢神経の損傷の治療用のトリペプチド配列ＫＤＩ。
- 脊髄損傷の治療用のトリペプチド配列ＫＤＩ。
- 脊髄損傷の治療用の、トリペプチドモチーフＫＤＩ（リジン−アスパラギン酸−イソロイシン）を包含する生物学的活性ペプチド。
- トリペプチドモチーフＫＤＩを包含する生物学的活性ペプチドを用いた、脊髄損傷治療剤の製造方法。
- トリペプチドモチーフＫＤＩを用いた、脊髄損傷治療剤の製造方法。
- 有効成分としてトリペプチドモチーフＫＤＩを包含し、医薬的に許容可能な担体および希釈剤からなる群より選ばれる少なくとも一種をさらに包含する医薬組成物。
- 注射可能な液体であることを特徴とする、請求項８に記載の医薬組成物。
- 有効成分であるペプチドの濃度が０．０１〜１００μｇ／ｍｌであることを特徴とする、請求項８または９に記載の医薬組成物。
- ミニポンプ システムを用いて脊髄の外傷領域に直接投与するための、請求項８〜１０のいずれかに記載の医薬組成物。
- 硬膜外腔注射によって投与するための、請求項８〜１０のいずれかに記載の医薬組成物。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20012082A FI20012082A0 (fi) | 2001-10-26 | 2001-10-26 | Biologisesti aktiiviset peptidit hermovauroiden korjaamiseksi |
| PCT/FI2002/000831 WO2003035675A1 (en) | 2001-10-26 | 2002-10-25 | Biologically active peptides and their use for repairing injured nerves |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005512979A JP2005512979A (ja) | 2005-05-12 |
| JP2005512979A5 true JP2005512979A5 (ja) | 2006-01-05 |
| JP4312054B2 JP4312054B2 (ja) | 2009-08-12 |
Family
ID=8562134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003538188A Expired - Fee Related JP4312054B2 (ja) | 2001-10-26 | 2002-10-25 | 生物学的活性ペプチドおよびそれを用いた損傷神経の修復 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20040266991A1 (ja) |
| EP (1) | EP1438329B1 (ja) |
| JP (1) | JP4312054B2 (ja) |
| AT (1) | ATE490972T1 (ja) |
| AU (1) | AU2002336124B2 (ja) |
| CA (1) | CA2465245C (ja) |
| DE (1) | DE60238551D1 (ja) |
| DK (1) | DK1438329T3 (ja) |
| FI (1) | FI20012082A0 (ja) |
| WO (1) | WO2003035675A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005029468A1 (de) * | 2005-06-24 | 2006-12-28 | Plt Patent & Licence Trading Ltd. | Verwendung von Inhibitoren der N-Methyltransferasen in der Therapie des Parkinson-Syndroms |
| RU2301678C1 (ru) | 2006-05-30 | 2007-06-27 | Общество С Ограниченной Ответственностью "Сиа Пептайдс" | Пептид, стимулирующий регенерацию нейронов центральной нервной системы, фармацевтическая композиция на его основе и способ ее применения |
| CA2692926A1 (en) * | 2007-05-31 | 2008-12-11 | The Hertz Corporation | System and method for automatically generating an airplane boarding pass for a traveler returning a rental car |
| US8008253B2 (en) | 2007-07-03 | 2011-08-30 | Andrew Tasker | Treatment for anxiety |
| US20090247466A1 (en) * | 2008-03-10 | 2009-10-01 | University Of Louisville Research Foundation | Neuroprotective integrin-binding peptide and angiopoietin-1 treatments |
| GB201700529D0 (en) * | 2017-01-12 | 2017-03-01 | Rogers April | Laminin receptor peptide |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT276041B (de) * | 1968-08-16 | 1969-11-10 | Dragoco Gerberding Co Gmbh | Verfahren zur Herstellung eines konzentrierten, praktisch sterilen Rohzwiebelaromas |
| US3590722A (en) * | 1969-06-09 | 1971-07-06 | Samuel Leptrone | Flavor injector device |
| HU185263B (en) | 1981-06-12 | 1984-12-28 | Richter Gedeon Vegyeszet | Process for producing peptides effective on the immuncontroll analogous with the tp5 |
| FI922517A (fi) * | 1992-05-29 | 1993-11-30 | Paeivi Liesi | Nervrepareringsmedel och dess anvaendning |
| GB9217316D0 (en) | 1992-08-14 | 1992-09-30 | Ludwig Inst Cancer Res | Schwann cell mitogenic factor,its preparation and use |
| GB9324473D0 (en) | 1993-11-29 | 1994-01-12 | Oxford Res Support Co Ltd | Isolation of streptokinase by affinity chromatography |
| CA2200209A1 (fr) * | 1995-07-26 | 1997-02-13 | Eric Frerot | Produits aromatises et procede pour leur preparation |
| US5721256A (en) * | 1997-02-12 | 1998-02-24 | Gpi Nil Holdings, Inc. | Method of using neurotrophic sulfonamide compounds |
| WO1998043686A1 (en) | 1997-04-03 | 1998-10-08 | California Institute Of Technology | Enzyme-mediated modification of fibrin for tissue engineering |
| US20020168718A1 (en) * | 1997-04-03 | 2002-11-14 | California Institute Of Technology | Enzyme-mediated modification of fibrin for tissue engineering |
| US6075119A (en) * | 1997-04-07 | 2000-06-13 | The Rockefeller University | Peptides useful for reducing symptoms of toxic shock syndrome |
| IL121191A0 (en) * | 1997-06-29 | 1997-11-20 | Yeda Res & Dev | Synthetic peptides and pharmaceutical compositions comprising them |
| JP2003525916A (ja) | 1999-04-22 | 2003-09-02 | エイドゲントシッシュ テクニーシェ ホッシュール チューリッヒ | モディファイドタンパク質マトリクス |
| DE20010297U1 (de) | 2000-06-08 | 2000-08-31 | Eth Zuerich Zuerich | Enzymvermittelte Modifizierung von Fibrin zur Gewebemanipulation: Fibrin-Formulierungen mit Peptiden |
-
2001
- 2001-10-26 FI FI20012082A patent/FI20012082A0/fi unknown
-
2002
- 2002-10-25 EP EP02770017A patent/EP1438329B1/en not_active Expired - Lifetime
- 2002-10-25 AU AU2002336124A patent/AU2002336124B2/en not_active Ceased
- 2002-10-25 JP JP2003538188A patent/JP4312054B2/ja not_active Expired - Fee Related
- 2002-10-25 US US10/492,850 patent/US20040266991A1/en not_active Abandoned
- 2002-10-25 DE DE60238551T patent/DE60238551D1/de not_active Expired - Lifetime
- 2002-10-25 WO PCT/FI2002/000831 patent/WO2003035675A1/en active Application Filing
- 2002-10-25 DK DK02770017.8T patent/DK1438329T3/da active
- 2002-10-25 AT AT02770017T patent/ATE490972T1/de not_active IP Right Cessation
- 2002-10-25 CA CA2465245A patent/CA2465245C/en not_active Expired - Fee Related
-
2005
- 2005-05-12 US US11/127,206 patent/US7659255B2/en not_active Expired - Fee Related
-
2008
- 2008-06-18 US US12/141,129 patent/US7741436B2/en not_active Expired - Fee Related
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