JP2005511722A - Birb796bsの投与方法 - Google Patents

Birb796bsの投与方法 Download PDF

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JP2005511722A
JP2005511722A JP2003550791A JP2003550791A JP2005511722A JP 2005511722 A JP2005511722 A JP 2005511722A JP 2003550791 A JP2003550791 A JP 2003550791A JP 2003550791 A JP2003550791 A JP 2003550791A JP 2005511722 A JP2005511722 A JP 2005511722A
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disease
dose
birb
active ingredient
crohn
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JP2005511722A5 (enExample
JP2005511722A6 (ja
Inventor
ピーター エム グロブ
ジェフリー ビー マドウェッド
クリストファー パーゲリス
チャン ロイ ヨン
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ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド
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Publication of JP2005511722A publication Critical patent/JP2005511722A/ja
Publication of JP2005511722A6 publication Critical patent/JP2005511722A6/ja
Publication of JP2005511722A5 publication Critical patent/JP2005511722A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
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    • A61P37/02Immunomodulators
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2003550791A 2001-12-11 2002-12-06 Birb796bsの投与方法 Pending JP2005511722A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33924901P 2001-12-11 2001-12-11
US60/339,249 2001-12-11
PCT/US2002/039289 WO2003049742A1 (en) 2001-12-11 2002-12-06 Method for administering birb 796 bs

Publications (3)

Publication Number Publication Date
JP2005511722A true JP2005511722A (ja) 2005-04-28
JP2005511722A6 JP2005511722A6 (ja) 2005-08-04
JP2005511722A5 JP2005511722A5 (enExample) 2006-02-02

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Family Applications (1)

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JP2003550791A Pending JP2005511722A (ja) 2001-12-11 2002-12-06 Birb796bsの投与方法

Country Status (6)

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US (2) US20030118575A1 (enExample)
EP (1) EP1455791A1 (enExample)
JP (1) JP2005511722A (enExample)
AU (1) AU2002366644A1 (enExample)
CA (1) CA2465759A1 (enExample)
WO (1) WO2003049742A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040110755A1 (en) * 2002-08-13 2004-06-10 Boehringer Ingelheim Pharmaceuticals, Inc. Combination therapy with p38 MAP kinase inhibitors and their pharmaceutical compositions
FR2846328B1 (fr) * 2002-10-23 2004-12-10 Servier Lab Nouveaux derives de l'imidazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
EP1658060A2 (en) * 2003-08-22 2006-05-24 Boehringer Ingelheim Pharmaceuticals Inc. Methods of treating copd and pulmonary hypertension
WO2005023761A2 (en) 2003-09-11 2005-03-17 Kemia, Inc. Cytokine inhibitors
JP2008523071A (ja) 2004-12-07 2008-07-03 ルーカス ファーマシューティカルズ, インコーポレイテッド Mapキナーゼの尿素インヒビター
JP2008523072A (ja) 2004-12-07 2008-07-03 ルーカス ファーマシューティカルズ, インコーポレイテッド タンパク質キナーゼの阻害剤
US20060190282A1 (en) * 2005-02-04 2006-08-24 Jung Edward K Providing risk mitigation in a virtual world
US7774275B2 (en) * 2005-02-28 2010-08-10 Searete Llc Payment options for virtual credit
US8473382B2 (en) * 2006-02-28 2013-06-25 The Invention Science Fund I, Llc Virtual collateral for real-world obligations
US20070156509A1 (en) * 2005-02-04 2007-07-05 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Real-world incentives offered to virtual world participants
US8556723B2 (en) * 2005-02-04 2013-10-15 The Invention Science Fund I. LLC Third party control over virtual world characters
US20080270165A1 (en) * 2005-02-04 2008-10-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Virtual world property disposition after real-world occurrence
US7937314B2 (en) * 2005-10-21 2011-05-03 The Invention Science Fund I Disposition of component virtual property rights
US8060829B2 (en) 2005-04-15 2011-11-15 The Invention Science Fund I, Llc Participation profiles of virtual world players
US20080103951A1 (en) * 2005-02-04 2008-05-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Virtual credit in simulated environments
US8457991B2 (en) * 2005-02-04 2013-06-04 The Invention Science Fund I, Llc Virtual credit in simulated environments
US20090144148A1 (en) * 2005-02-04 2009-06-04 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Attribute enhancement in virtual world environments
US7890419B2 (en) * 2005-02-04 2011-02-15 The Invention Science Fund I, Llc Virtual credit in simulated environments
US20070198305A1 (en) * 2005-03-30 2007-08-23 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Virtual credit with transferability
US7720687B2 (en) 2005-10-03 2010-05-18 The Invention Science Fund I, Llc Virtual world property disposition after real-world occurrence
US20080215434A1 (en) * 2005-02-04 2008-09-04 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Real world interaction with virtual world privileges
US7958047B2 (en) 2005-02-04 2011-06-07 The Invention Science Fund I Virtual credit in simulated environments
US20090099930A1 (en) * 2005-02-04 2009-04-16 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Participation profiles of virtual world players
US20080092065A1 (en) * 2005-02-04 2008-04-17 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Third party control over virtual world characters
US20070013691A1 (en) * 2005-07-18 2007-01-18 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Supervisory authority in virtual world environment
US20070118420A1 (en) * 2005-02-04 2007-05-24 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Context determinants in virtual world environment
US8566111B2 (en) * 2005-02-04 2013-10-22 The Invention Science Fund I, Llc Disposition of component virtual property rights
US8512143B2 (en) * 2005-07-18 2013-08-20 The Invention Science Fund I, Llc Third party control over virtual world characters
US8271365B2 (en) * 2005-02-04 2012-09-18 The Invention Science Fund I, Llc Real-world profile data for making virtual world contacts
US20070168214A1 (en) * 2005-03-30 2007-07-19 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Virtual credit with transferability
US20090043683A1 (en) * 2005-02-04 2009-02-12 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Virtual world reversion rights
US20090138333A1 (en) * 2005-02-04 2009-05-28 Searete Llc, A Limited Liablity Of The State Of Delaware Follow-up contacts with virtual world participants
US20070078737A1 (en) * 2005-02-28 2007-04-05 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Financial ventures based on virtual credit
WO2008079629A2 (en) * 2006-12-21 2008-07-03 Boehringer Ingelheim International Gmbh Formulations with improved bioavailability
EP3257862A1 (en) 2016-06-16 2017-12-20 ETH Zürich Fibronectin-binding peptides for use in tumor or fibrosis diagnosis and therapy
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
PT3691620T (pt) 2017-10-05 2022-10-06 Fulcrum Therapeutics Inc Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105766A (en) * 1977-08-19 1978-08-08 Sterling Drug Inc. 4,5-Dihydro-5-oxopyrazolo[1,5-a]quinazoline-3-carboxylic acid derivatives
HU185294B (en) * 1980-12-29 1984-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing substituted urea derivatives
US5162360A (en) * 1991-06-24 1992-11-10 Warner-Lambert Company 2-heteroatom containing urea and thiourea ACAT inhibitors
IL104369A0 (en) * 1992-01-13 1993-05-13 Smithkline Beecham Corp Novel compounds and compositions
EP0724588B1 (en) * 1993-09-17 1999-11-10 Smithkline Beecham Corporation Drug binding protein
US5869043A (en) * 1993-09-17 1999-02-09 Smithkline Beecham Corporation Drug binding protein
US5783664A (en) * 1993-09-17 1998-07-21 Smithkline Beecham Corporation Cytokine suppressive anit-inflammatory drug binding proteins
US5739143A (en) * 1995-06-07 1998-04-14 Smithkline Beecham Corporation Imidazole compounds and compositions
US5948885A (en) * 1996-05-20 1999-09-07 Signal Pharmaceuticals, Inc. Mitogen-activated protein kinase p38-2 and methods of use therefor
ES2239357T3 (es) * 1996-06-10 2005-09-16 MERCK & CO., INC. Imidazoles sustituidos que tienen actividad inhibidora de citoquinas.
US5851812A (en) * 1997-07-01 1998-12-22 Tularik Inc. IKK-β proteins, nucleic acids and methods
UA73492C2 (en) * 1999-01-19 2005-08-15 Aromatic heterocyclic compounds as antiinflammatory agents
WO2000050425A1 (en) * 1999-02-22 2000-08-31 Boehringer Ingelheim Pharmaceuticals, Inc. Polycyclo heterocyclic derivatives as antiinflammatory agents
US6565880B2 (en) * 2000-07-24 2003-05-20 Boehringer Ingelheim Pharmaceuticals, Inc. Oral dosage formulations of 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea
WO2003015828A1 (en) * 2001-08-20 2003-02-27 Boehringer Ingelheim Pharmaceuticals, Inc. Parenteral formulations of 1-(5-tert-butyl-2-p-tolyl-2h-pryrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea and a cyclodextrin
JP2005506350A (ja) * 2001-10-18 2005-03-03 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド サイトカイン阻害薬としての1,4−二置換ベンゾ−縮合尿素化合物

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AU2002366644A1 (en) 2003-06-23
US20070203141A1 (en) 2007-08-30
WO2003049742A1 (en) 2003-06-19
US20030118575A1 (en) 2003-06-26
CA2465759A1 (en) 2003-06-19
EP1455791A1 (en) 2004-09-15

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