JP2005511667A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005511667A5 JP2005511667A5 JP2003549274A JP2003549274A JP2005511667A5 JP 2005511667 A5 JP2005511667 A5 JP 2005511667A5 JP 2003549274 A JP2003549274 A JP 2003549274A JP 2003549274 A JP2003549274 A JP 2003549274A JP 2005511667 A5 JP2005511667 A5 JP 2005511667A5
- Authority
- JP
- Japan
- Prior art keywords
- olefin
- aryl
- sulfonate
- bromine
- iodine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims 2
- 150000001336 alkenes Chemical class 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 claims 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- 150000001491 aromatic compounds Chemical class 0.000 claims 1
- -1 aryl olefins Chemical class 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 239000003054 catalyst Substances 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 239000011630 iodine Substances 0.000 claims 1
- 229910052740 iodine Inorganic materials 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052763 palladium Inorganic materials 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10159270A DE10159270A1 (de) | 2001-12-03 | 2001-12-03 | Verfahren zur Arylierung von Olefinen |
| PCT/EP2002/012993 WO2003048079A2 (de) | 2001-12-03 | 2002-11-20 | Verfahren zur arylierung von olefinen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005511667A JP2005511667A (ja) | 2005-04-28 |
| JP2005511667A5 true JP2005511667A5 (enExample) | 2006-01-05 |
| JP4386729B2 JP4386729B2 (ja) | 2009-12-16 |
Family
ID=7707839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003549274A Expired - Fee Related JP4386729B2 (ja) | 2001-12-03 | 2002-11-20 | オレフィンのアリール化法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7102046B2 (enExample) |
| EP (1) | EP1453774B1 (enExample) |
| JP (1) | JP4386729B2 (enExample) |
| AT (1) | ATE421491T1 (enExample) |
| AU (1) | AU2002356692A1 (enExample) |
| DE (2) | DE10159270A1 (enExample) |
| ES (1) | ES2318065T3 (enExample) |
| IL (2) | IL162237A0 (enExample) |
| WO (1) | WO2003048079A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2240451T3 (da) | 2008-01-04 | 2017-11-20 | Intellikine Llc | Isoquinolinonderivater substitueret med en purin, der er anvendelig som pi3k-inhibitorer |
| US8193182B2 (en) | 2008-01-04 | 2012-06-05 | Intellikine, Inc. | Substituted isoquinolin-1(2H)-ones, and methods of use thereof |
| DK2663309T3 (en) | 2011-01-10 | 2017-06-19 | Infinity Pharmaceuticals Inc | METHODS FOR PRODUCING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES |
| US8828998B2 (en) | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| KR102229478B1 (ko) | 2012-11-01 | 2021-03-18 | 인피니티 파마슈티칼스, 인코포레이티드 | Pi3 키나아제 동형단백질 조절인자를 사용하는 암의 치료 |
| FR2997696B1 (fr) * | 2012-11-08 | 2014-12-05 | Servier Lab | Nouveau procede de synthese du (2e)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
| US20150320755A1 (en) | 2014-04-16 | 2015-11-12 | Infinity Pharmaceuticals, Inc. | Combination therapies |
| IL263680B2 (en) | 2016-06-24 | 2025-10-01 | Infinity Pharmaceuticals Inc | PI3K inhibitors for use in combination with a second therapeutic agent for the treatment, management or prevention of cancer |
| EP3945105A1 (en) | 2020-07-30 | 2022-02-02 | Basf Se | Process for preparing a hydroxy group functionalized thioether |
-
2001
- 2001-12-03 DE DE10159270A patent/DE10159270A1/de not_active Withdrawn
-
2002
- 2002-11-20 EP EP02804186A patent/EP1453774B1/de not_active Expired - Lifetime
- 2002-11-20 IL IL16223702A patent/IL162237A0/xx unknown
- 2002-11-20 DE DE50213245T patent/DE50213245D1/de not_active Expired - Lifetime
- 2002-11-20 ES ES02804186T patent/ES2318065T3/es not_active Expired - Lifetime
- 2002-11-20 WO PCT/EP2002/012993 patent/WO2003048079A2/de not_active Ceased
- 2002-11-20 AT AT02804186T patent/ATE421491T1/de not_active IP Right Cessation
- 2002-11-20 AU AU2002356692A patent/AU2002356692A1/en not_active Abandoned
- 2002-11-20 JP JP2003549274A patent/JP4386729B2/ja not_active Expired - Fee Related
- 2002-11-27 US US10/305,880 patent/US7102046B2/en not_active Expired - Fee Related
-
2004
- 2004-05-31 IL IL162237A patent/IL162237A/en not_active IP Right Cessation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE464312T1 (de) | Organometallische übergangsmetallverbindung, biscyclopentadienylligandensystem, katalysatorsystem und herstellung von polyolefinen | |
| JP2005511667A5 (enExample) | ||
| JP2003506494A5 (enExample) | ||
| JP2004538039A5 (enExample) | ||
| IL175024A0 (en) | Method for producing 2-dihaloacyl-3-amino-acrylic acid esters and 3-dihalomethyl-pyrazole-4-carboxylic acid esters | |
| JP2006509054A5 (enExample) | ||
| CA2447644A1 (en) | Preparation of olefin polymerisation catalyst component | |
| Qiao et al. | 5-Amidinobenzo [b] thiophenes as dual inhibitors of factors IXa and Xa | |
| JP2005511682A5 (enExample) | ||
| BR9910750B1 (pt) | catalisador para a produção de acetato de vinila por reação de etileno, oxigênio e ácido acético. | |
| JP2009503079A5 (enExample) | ||
| JPH0912621A5 (enExample) | ||
| BRPI0518647A2 (pt) | processo para a produÇço de um composto, e, composto | |
| EP1671937A4 (en) | METHOD FOR PRODUCING A NITRILE COMPOUND, CARBOXYLIC COMPOUND OR CARBOXYLATE COMPOUND | |
| JP2004520293A5 (enExample) | ||
| JP2004149545A5 (enExample) | ||
| JP2005537219A5 (enExample) | ||
| CA2447803A1 (en) | Synthesis of 4-phenylbutyric acid | |
| WO1999067232A3 (en) | Process for the preparation of 3-aryl-benzofuranones | |
| AU2002354100A1 (en) | Process for preparation of diphosphine compounds and intermediates for the process | |
| JP2005523934A5 (enExample) | ||
| JP2006188509A5 (enExample) | ||
| WO2003048079A3 (de) | Verfahren zur arylierung von olefinen | |
| MXPA05013604A (es) | Procedimiento para preparar acilsulfamoilbenzamidas. | |
| EP1571144A4 (en) | HYDROXYALKYLATED CYCLIC DEDIAMINE COMPOUND |