JP2005508352A - 新規ベンゾチアジン誘導体、その製造方法及びその使用方法 - Google Patents

新規ベンゾチアジン誘導体、その製造方法及びその使用方法 Download PDF

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Publication number
JP2005508352A
JP2005508352A JP2003534405A JP2003534405A JP2005508352A JP 2005508352 A JP2005508352 A JP 2005508352A JP 2003534405 A JP2003534405 A JP 2003534405A JP 2003534405 A JP2003534405 A JP 2003534405A JP 2005508352 A JP2005508352 A JP 2005508352A
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JP
Japan
Prior art keywords
alkyl
cycloalkyl
sulfonyl
benzo
thiazine
Prior art date
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Withdrawn
Application number
JP2003534405A
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English (en)
Japanese (ja)
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JP2005508352A5 (https=
Inventor
ゴウリエフ・アレックス・ハール
ラルセン・モーゲンス
ヴァルミング・トーマス
マチーセン・クラウス
ヨハンセン・チナ・ホルム
ニールセン・カリン・サンダガー
ハルツ・バルバラ
シェール−クリューガー・イェルゲン
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NTG Nordic Transport Group AS
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Neurosearch AS
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Publication date
Application filed by Neurosearch AS filed Critical Neurosearch AS
Publication of JP2005508352A publication Critical patent/JP2005508352A/ja
Publication of JP2005508352A5 publication Critical patent/JP2005508352A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2003534405A 2001-10-10 2002-10-02 新規ベンゾチアジン誘導体、その製造方法及びその使用方法 Withdrawn JP2005508352A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101498 2001-10-10
PCT/DK2002/000654 WO2003031422A1 (en) 2001-10-10 2002-10-02 Novel benzothiazine derivatives, their preparation and use

Publications (2)

Publication Number Publication Date
JP2005508352A true JP2005508352A (ja) 2005-03-31
JP2005508352A5 JP2005508352A5 (https=) 2006-01-05

Family

ID=8160760

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003534405A Withdrawn JP2005508352A (ja) 2001-10-10 2002-10-02 新規ベンゾチアジン誘導体、その製造方法及びその使用方法

Country Status (8)

Country Link
US (1) US7199118B2 (https=)
EP (1) EP1436270A1 (https=)
JP (1) JP2005508352A (https=)
CN (1) CN1275951C (https=)
CA (1) CA2458388A1 (https=)
MX (1) MXPA04003297A (https=)
NZ (1) NZ531511A (https=)
WO (1) WO2003031422A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3547859B2 (ja) * 1995-07-14 2004-07-28 愛知機械工業株式会社 ２方向差動クラッチ
FR2856064B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2933698A1 (fr) 2008-07-09 2010-01-15 Servier Lab Nouveaux derives de benzothiadiazines cycloalkylees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2955107B1 (fr) * 2010-01-08 2012-03-02 Servier Lab Nouveaux derives thiochromanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US9150591B2 (en) 2010-08-10 2015-10-06 Takeda Pharmaceutical Company Limited Heterocyclic compound and use thereof
CR20220160A (es) 2019-09-16 2022-06-16 Takeda Pharmaceuticals Co Derivados de piridazin-3(2h)-ona fusionados con azol
CN111393385B (zh) * 2020-04-15 2022-01-18 华南理工大学 一种苯并噻嗪甲醛衍生物的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3113075A (en) * 1960-10-17 1963-12-03 Merck & Co Inc Heterocyclic compounds
DE1302858B (https=) * 1962-09-21 1972-05-04
FR1552763A (https=) * 1963-11-08 1969-01-10
FR3136M (fr) * 1963-11-08 1965-02-15 Merck & Co Inc Nouveaux médicaments diurétiques.
CN1293665A (zh) * 1998-02-18 2001-05-02 神经研究公司 新化合物及其用作阳性ampa受体调节剂
DE10004572A1 (de) * 2000-02-02 2001-08-09 Boehringer Ingelheim Pharma Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel

Also Published As

Publication number Publication date
WO2003031422A1 (en) 2003-04-17
EP1436270A1 (en) 2004-07-14
CA2458388A1 (en) 2003-04-17
CN1564817A (zh) 2005-01-12
CN1275951C (zh) 2006-09-20
MXPA04003297A (es) 2004-07-23
US20040242571A1 (en) 2004-12-02
US7199118B2 (en) 2007-04-03
NZ531511A (en) 2006-01-27

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